Published in Schizophr Res on October 24, 2007
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Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2. Science (2003) 8.48
Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action. Nat Neurosci (2006) 8.24
Covalent modification of DNA regulates memory formation. Neuron (2007) 6.20
CBP histone acetyltransferase activity is a critical component of memory consolidation. Neuron (2004) 5.40
Chromatin acetylation, memory, and LTP are impaired in CBP+/- mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration. Neuron (2004) 5.35
Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus. J Biol Chem (2006) 3.47
Reelin promoter hypermethylation in schizophrenia. Proc Natl Acad Sci U S A (2005) 3.12
DNA hypomethylation perturbs the function and survival of CNS neurons in postnatal animals. J Neurosci (2001) 2.75
Regulation of the GABA cell phenotype in hippocampus of schizophrenics and bipolars. Proc Natl Acad Sci U S A (2007) 2.72
Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder. Hum Mol Genet (2006) 2.53
Molecular and cellular mechanisms of altered GAD1/GAD67 expression in schizophrenia and related disorders. Brain Res Rev (2006) 2.36
Hypermethylation of the reelin (RELN) promoter in the brain of schizophrenic patients: a preliminary report. Am J Med Genet B Neuropsychiatr Genet (2005) 2.34
DNA methyltransferase inhibitors coordinately induce expression of the human reelin and glutamic acid decarboxylase 67 genes. Mol Pharmacol (2006) 1.95
An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerability. Proc Natl Acad Sci U S A (2002) 1.91
HATs and HDACs in neurodegeneration: a tale of disconcerted acetylation homeostasis. Cell Death Differ (2006) 1.82
Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice. Biol Psychiatry (2005) 1.74
In psychosis, cortical interneurons overexpress DNA-methyltransferase 1. Proc Natl Acad Sci U S A (2005) 1.72
The benzamide MS-275 is a potent, long-lasting brain region-selective inhibitor of histone deacetylases. Proc Natl Acad Sci U S A (2006) 1.71
DNA-methyltransferase 1 mRNA is selectively overexpressed in telencephalic GABAergic interneurons of schizophrenia brains. Proc Natl Acad Sci U S A (2003) 1.71
On the epigenetic regulation of the human reelin promoter. Nucleic Acids Res (2002) 1.69
Reelin and glutamic acid decarboxylase67 promoter remodeling in an epigenetic methionine-induced mouse model of schizophrenia. Proc Natl Acad Sci U S A (2005) 1.56
Selective epigenetic alteration of layer I GABAergic neurons isolated from prefrontal cortex of schizophrenia patients using laser-assisted microdissection. Mol Psychiatry (2007) 1.39
Epigenetic mechanisms expressed in basal ganglia GABAergic neurons differentiate schizophrenia from bipolar disorder. Schizophr Res (2007) 1.34
DNA methyltransferase 1 regulates reelin mRNA expression in mouse primary cortical cultures. Proc Natl Acad Sci U S A (2005) 1.26
Valproic acid and chromatin remodeling in schizophrenia and bipolar disorder: preliminary results from a clinical population. Schizophr Res (2006) 1.18
Chromatin alterations associated with down-regulated metabolic gene expression in the prefrontal cortex of subjects with schizophrenia. Arch Gen Psychiatry (2005) 1.17
S-adenosyl methionine and DNA methyltransferase-1 mRNA overexpression in psychosis. Neuroreport (2007) 1.17
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DNA methyltransferase inhibitors coordinately induce expression of the human reelin and glutamic acid decarboxylase 67 genes. Mol Pharmacol (2006) 1.95
GABAergic dysfunction in schizophrenia: new treatment strategies on the horizon. Psychopharmacology (Berl) (2005) 1.82
Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice. Biol Psychiatry (2005) 1.74
Reviewing the role of DNA (cytosine-5) methyltransferase overexpression in the cortical GABAergic dysfunction associated with psychosis vulnerability. Epigenetics (2007) 1.70
On the epigenetic regulation of the human reelin promoter. Nucleic Acids Res (2002) 1.69
A reelin-integrin receptor interaction regulates Arc mRNA translation in synaptoneurosomes. Proc Natl Acad Sci U S A (2003) 1.38
DNA methyltransferase 1 regulates reelin mRNA expression in mouse primary cortical cultures. Proc Natl Acad Sci U S A (2005) 1.26
The reelin and GAD67 promoters are activated by epigenetic drugs that facilitate the disruption of local repressor complexes. Mol Pharmacol (2008) 1.22
Epigenetic modifications of GABAergic interneurons are associated with the schizophrenia-like phenotype induced by prenatal stress in mice. Neuropharmacology (2012) 1.21
Valproate induces DNA demethylation in nuclear extracts from adult mouse brain. Epigenetics (2010) 1.20
Valproic acid and chromatin remodeling in schizophrenia and bipolar disorder: preliminary results from a clinical population. Schizophr Res (2006) 1.18
Characterization of the action of antipsychotic subtypes on valproate-induced chromatin remodeling. Trends Pharmacol Sci (2008) 1.17
S-adenosyl methionine and DNA methyltransferase-1 mRNA overexpression in psychosis. Neuroreport (2007) 1.17
Histone deacetylase inhibitors decrease reelin promoter methylation in vitro. J Neurochem (2005) 1.16
Dimethylated lysine 9 of histone 3 is elevated in schizophrenia and exhibits a divergent response to histone deacetylase inhibitors in lymphocyte cultures. J Psychiatry Neurosci (2009) 0.99
Depolarization induces downregulation of DNMT1 and DNMT3a in primary cortical cultures. Epigenetics (2008) 0.98
Quantitative reverse transcription-polymerase chain reaction of GABA(A) alpha1, beta1 and gamma2S subunits in epileptic rats following photothrombotic infarction of neocortex. Epilepsy Res (2002) 0.96
GABAergic promoter hypermethylation as a model to study the neurochemistry of schizophrenia vulnerability. Expert Rev Neurother (2009) 0.96
Analysis of the GAD1 promoter: trans-acting factors and DNA methylation converge on the 5' untranslated region. Neuropharmacology (2010) 0.95
Epigenetic downregulation of GABAergic function in schizophrenia: potential for pharmacological intervention? Mol Interv (2003) 0.95
GABAergic cortical neuron chromatin as a putative target to treat schizophrenia vulnerability. Crit Rev Neurobiol (2003) 0.94
Expression of GABA A receptor alpha1 subunit mRNA and protein in rat neocortex following photothrombotic infarction. Brain Res (2008) 0.92
Induction of the reelin promoter by retinoic acid is mediated by Sp1. J Neurochem (2007) 0.92
Imidazenil and diazepam increase locomotor activity in mice exposed to protracted social isolation. Proc Natl Acad Sci U S A (2006) 0.91
Chromatin, DNA methylation and neuron gene regulation--the purpose of the package. J Psychiatry Neurosci (2005) 0.91
Reduced baseline acetylated histone 3 levels, and a blunted response to HDAC inhibition in lymphocyte cultures from schizophrenia subjects. Schizophr Res (2008) 0.91
CpG methylation in neurons: message, memory, or mask? Neuropsychopharmacology (2010) 0.89
Prefrontal cortical dysfunction after overexpression of histone deacetylase 1. Biol Psychiatry (2013) 0.89
Histone methylation at H3K9: evidence for a restrictive epigenome in schizophrenia. Schizophr Res (2013) 0.88
DNA methyltransferases1 (DNMT1) and 3a (DNMT3a) colocalize with GAD67-positive neurons in the GAD67-GFP mouse brain. J Comp Neurol (2012) 0.86
DNA methylation/demethylation network expression in psychotic patients with a history of alcohol abuse. Alcohol Clin Exp Res (2012) 0.86
Krüppel-like factor 2 regulated gene expression in mouse embryonic yolk sac erythroid cells. Blood Cells Mol Dis (2011) 0.85
Antipsychotic subtypes can be characterized by differences in their ability to modify GABAergic promoter methylation. Epigenomics (2009) 0.84
Characterization of wild-type (R100R) and mutated (Q100Q) GABAA alpha 6 subunit in Sardinian alcohol non-preferring rats (sNP). Brain Res (2003) 0.82
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Neonatal lesions of the ventral hippocampal formation alter GABA-A receptor subunit mRNA expression in adult rat frontal pole. Biol Psychiatry (2005) 0.79
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Differential effects of prenatal cocaine exposure on selected subunit mRNAs of the GABA(A) receptor in rabbit anterior cingulate cortex. J Chem Neuroanat (2002) 0.75