PubRank

Reinhard Sedlmeier

Author PubWeight™ 15.87‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Random mutagenesis in the mouse as a tool in drug discovery. Drug Discov Today 2002 2.23
2 TRESK two-pore-domain K+ channels constitute a significant component of background potassium currents in murine dorsal root ganglion neurones. J Physiol 2007 1.51
3 Mast cells increase vascular permeability by heparin-initiated bradykinin formation in vivo. Immunity 2011 1.46
4 Heterozygous R1101K mutation of the DCTN1 gene in a family with ALS and FTD. Ann Neurol 2005 1.42
5 Selective hippocampal neurodegeneration in transgenic mice expressing small amounts of truncated Aβ is induced by pyroglutamate-Aβ formation. J Neurosci 2011 1.08
6 The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions. EMBO Mol Med 2011 0.96
7 Use of an exon-trapping vector for the evaluation of splice-site mutations. Mamm Genome 2007 0.94
8 Negative-strand RNA viral vectors: intravenous application of Sendai virus vectors for the systemic delivery of therapeutic genes. Mol Ther 2003 0.87
9 Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in plasma enzyme activities as novel organ-specific disease models. Exp Physiol 2009 0.85
10 N-ethyl-N-nitrosourea-based generation of mouse models for mutant G protein-coupled receptors. Physiol Genomics 2006 0.83
11 Glutaminyl cyclase knock-out mice exhibit slight hypothyroidism but no hypogonadism: implications for enzyme function and drug development. J Biol Chem 2011 0.81
12 Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in hematological parameters. Mamm Genome 2011 0.81
13 Glutaminyl cyclase-mediated toxicity of pyroglutamate-beta amyloid induces striatal neurodegeneration. BMC Neurosci 2013 0.79
14 Dual function of the UNC-45b chaperone with myosin and GATA4 in cardiac development. J Cell Sci 2012 0.78
15 IsoQC (QPCTL) knock-out mice suggest differential substrate conversion by glutaminyl cyclase isoenzymes. Biol Chem 2016 0.76
16 Screen for alterations of iron related parameters in N-ethyl-N-nitrosourea-treated mice identified mutant lines with increased plasma ferritin levels. Biometals 2015 0.75