Paul A Slesinger

Author PubWeight™ 43.45‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Cytoplasmic domain structures of Kir2.1 and Kir3.1 show sites for modulating gating and rectification. Nat Neurosci 2005 3.22
2 Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease. Nat Rev Neurosci 2010 2.69
3 Bi-directional effects of GABA(B) receptor agonists on the mesolimbic dopamine system. Nat Neurosci 2004 2.30
4 Genetically encoding unnatural amino acids for cellular and neuronal studies. Nat Neurosci 2007 1.76
5 Basal GABA regulates GABA(B)R conformation and release probability at single hippocampal synapses. Neuron 2010 1.64
6 A unique sorting nexin regulates trafficking of potassium channels via a PDZ domain interaction. Nat Neurosci 2007 1.63
7 RGS2 modulates coupling between GABAB receptors and GIRK channels in dopamine neurons of the ventral tegmental area. Nat Neurosci 2007 1.58
8 A discrete alcohol pocket involved in GIRK channel activation. Nat Neurosci 2009 1.49
9 Evidence for association of GABA(B) receptors with Kir3 channels and regulators of G protein signalling (RGS4) proteins. J Physiol 2006 1.45
10 Andersen's syndrome mutation effects on the structure and assembly of the cytoplasmic domains of Kir2.1. Biochemistry 2006 1.30
11 Mechanism underlying selective regulation of G protein-gated inwardly rectifying potassium channels by the psychostimulant-sensitive sorting nexin 27. Proc Natl Acad Sci U S A 2011 1.28
12 Evidence for a centrally located gate in the pore of a serotonin-gated ion channel. J Neurosci 2002 1.26
13 GABAB receptor coupling to G-proteins and ion channels. Adv Pharmacol 2010 1.22
14 betaL-betaM loop in the C-terminal domain of G protein-activated inwardly rectifying K(+) channels is important for G(betagamma) subunit activation. J Physiol 2004 1.18
15 Pertussis-toxin-sensitive Galpha subunits selectively bind to C-terminal domain of neuronal GIRK channels: evidence for a heterotrimeric G-protein-channel complex. Mol Cell Neurosci 2005 1.16
16 Facile backbone structure determination of human membrane proteins by NMR spectroscopy. Nat Methods 2012 1.16
17 Methamphetamine-evoked depression of GABA(B) receptor signaling in GABA neurons of the VTA. Neuron 2012 1.01
18 The role of the cytoplasmic pore in inward rectification of Kir2.1 channels. J Gen Physiol 2007 0.99
19 In vivo expression of a light-activatable potassium channel using unnatural amino acids. Neuron 2013 0.99
20 Alcohol-binding sites in distinct brain proteins: the quest for atomic level resolution. Alcohol Clin Exp Res 2011 0.99
21 Compartmentalization of the GABAB receptor signaling complex is required for presynaptic inhibition at hippocampal synapses. J Neurosci 2011 0.95
22 Regulation of Kir2.1 channels by the Rho-GTPase, Rac1. J Cell Physiol 2009 0.93
23 Endogenous RGS proteins enhance acute desensitization of GABA(B) receptor-activated GIRK currents in HEK-293T cells. Pflugers Arch 2004 0.91
24 Direct interaction of GABAB receptors with M2 muscarinic receptors enhances muscarinic signaling. J Neurosci 2009 0.90
25 Addictive drugs modulate GIRK-channel signaling by regulating RGS proteins. Trends Pharmacol Sci 2008 0.89
26 Morphine- and CaMKII-dependent enhancement of GIRK channel signaling in hippocampal neurons. J Neurosci 2010 0.88
27 Ras-association domain of sorting Nexin 27 is critical for regulating expression of GIRK potassium channels. PLoS One 2013 0.86
28 NMR studies of interactions between C-terminal tail of Kir2.1 channel and PDZ1,2 domains of PSD95. Biochemistry 2007 0.86
29 Coregulation of natively expressed pertussis toxin-sensitive muscarinic receptors with G-protein-activated potassium channels. J Neurosci 2007 0.85
30 Minimal structural rearrangement of the cytoplasmic pore during activation of the 5-HT3A receptor. J Biol Chem 2004 0.85
31 Molecular mechanism underlying ethanol activation of G-protein-gated inwardly rectifying potassium channels. Proc Natl Acad Sci U S A 2013 0.83
32 Subunit-specific regulation of Kir3 channels by sorting nexin 27. Channels (Austin) 2007 0.83
33 Firing modes of dopamine neurons drive bidirectional GIRK channel plasticity. J Neurosci 2014 0.82
34 Mutagenesis and functional analysis of ion channels heterologously expressed in mammalian cells. J Vis Exp 2010 0.81
35 Organotypic cerebellar cultures: apoptotic challenges and detection. J Vis Exp 2011 0.80
36 Probing novel GPCR interactions using a combination of FRET and TIRF. Commun Integr Biol 2010 0.77
37 Preface. Int Rev Neurobiol 2015 0.75