Published in Circ Res on October 25, 2007
Smad-independent transforming growth factor-beta regulation of early growth response-1 and sustained expression in fibrosis: implications for scleroderma. Am J Pathol (2008) 1.30
Egr-1: new conductor for the tissue repair orchestra directs harmony (regeneration) or cacophony (fibrosis). J Pathol (2012) 1.21
Hemolysis-induced lethality involves inflammasome activation by heme. Proc Natl Acad Sci U S A (2014) 1.20
Early growth response transcription factors: key mediators of fibrosis and novel targets for anti-fibrotic therapy. Matrix Biol (2011) 1.10
Xanthine oxidase-derived ROS upregulate Egr-1 via ERK1/2 in PA smooth muscle cells; model to test impact of extracellular ROS in chronic hypoxia. PLoS One (2011) 1.09
Disease progression mediated by egr-1 associated signaling in response to oxidative stress. Int J Mol Sci (2012) 1.03
Heme oxygenase, inflammation, and fibrosis: the good, the bad, and the ugly? Front Pharmacol (2012) 0.97
Direct recruitment of ERK cascade components to inducible genes is regulated by heterogeneous nuclear ribonucleoprotein (hnRNP) K. J Biol Chem (2011) 0.96
Aldose reductase drives hyperacetylation of Egr-1 in hyperglycemia and consequent upregulation of proinflammatory and prothrombotic signals. Diabetes (2013) 0.89
Sequential activation of Elk-1/Egr-1/GADD45α by arsenic. Oncotarget (2014) 0.83
Butyric acid retention in gingival tissue induces oxidative stress in jugular blood mitochondria. Cell Stress Chaperones (2013) 0.82
The Role of Heme and Reactive Oxygen Species in Proliferation and Survival of Trypanosoma cruzi. J Parasitol Res (2011) 0.81
Cellular MicroRNA Let-7a Suppresses KSHV Replication through Targeting MAP4K4 Signaling Pathways. PLoS One (2015) 0.79
Atherogenic ω-6 Lipids Modulate PPAR- EGR-1 Crosstalk in Vascular Cells. PPAR Res (2011) 0.79
High ambient glucose augments angiotensin II-induced proinflammatory gene mRNA expression in human mesangial cells: effects of valsartan and simvastatin. Am J Nephrol (2009) 0.79
Heme Egr-1: new partners in atherosclerotic progression? Circ Res (2008) 0.78
Inhalation of carbon monoxide reduces skeletal muscle injury after hind limb ischemia-reperfusion injury in mice. Am J Surg (2012) 0.78
Iron deficiency upregulates Egr1 expression. Genes Nutr (2015) 0.78
Combination of two rare mutations causes β-thalassaemia in a Bangladeshi patient. Genet Mol Biol (2011) 0.78
Hyperglycemia: GDNF-EGR1 pathway target renal epithelial cell migration and apoptosis in diabetic renal embryopathy. PLoS One (2013) 0.77
Transcription factors involved in prostate gland adaptation to androgen deprivation. PLoS One (2014) 0.77
Increased Expression of EGR-1 in Diabetic Human Adipose Tissue-Derived Mesenchymal Stem Cells Reduces Their Wound Healing Capacity. Stem Cells Dev (2016) 0.77
Activation of Egr-1 in human lung epithelial cells exposed to silica through MAPKs signaling pathways. PLoS One (2013) 0.77
High butyric acid amounts induce oxidative stress, alter calcium homeostasis, and cause neurite retraction in nerve growth factor-treated PC12 cells. Cell Stress Chaperones (2015) 0.77
Transcription Mapping of Embryonic Rat Brain Reveals EGR-1 Induction in SOX2 Neural Progenitor Cells. Front Mol Neurosci (2011) 0.77
C2238/αANP modulates apolipoprotein E through Egr-1/miR199a in vascular smooth muscle cells in vitro. Cell Death Dis (2015) 0.77
Time course analysis of gene expression identifies multiple genes with differential expression in patients with in-stent restenosis. BMC Med Genomics (2011) 0.77
PDGF induces SphK1 expression via Egr-1 to promote pulmonary artery smooth muscle cell proliferation. Am J Physiol Cell Physiol (2016) 0.76
Pitavastatin suppresses mitogen activated protein kinase-mediated Erg-1 induction in human vascular smooth muscle cells. Eur J Pharmacol (2009) 0.76
SARS coronavirus papain-like protease induces Egr-1-dependent up-regulation of TGF-β1 via ROS/p38 MAPK/STAT3 pathway. Sci Rep (2016) 0.75
In Support of a Patient-Driven Initiative and Petition to Lower the High Price of Cancer Drugs. Mayo Clin Proc (2015) 4.70
Hyperhomocysteinemia decreases circulating high-density lipoprotein by inhibiting apolipoprotein A-I Protein synthesis and enhancing HDL cholesterol clearance. Circ Res (2006) 1.95
Hyperhomocysteinemia impairs endothelium-derived hyperpolarizing factor-mediated vasorelaxation in transgenic cystathionine beta synthase-deficient mice. Blood (2011) 1.77
Hyperhomocysteinemia accelerates atherosclerosis in cystathionine beta-synthase and apolipoprotein E double knock-out mice with and without dietary perturbation. Blood (2002) 1.59
Hyperhomocystinemia impairs endothelial function and eNOS activity via PKC activation. Arterioscler Thromb Vasc Biol (2005) 1.52
Heme oxygenase-1-derived carbon monoxide is an autocrine inhibitor of vascular smooth muscle cell growth. Blood (2002) 1.39
Homocysteine inhibits endothelial cell growth via DNA hypomethylation of the cyclin A gene. Blood (2007) 1.31
Hyperhomocysteinemia promotes inflammatory monocyte generation and accelerates atherosclerosis in transgenic cystathionine beta-synthase-deficient mice. Circulation (2009) 1.30
Cyclin A transcriptional suppression is the major mechanism mediating homocysteine-induced endothelial cell growth inhibition. Blood (2002) 1.29
Carbon monoxide inhibits apoptosis in vascular smooth muscle cells. Cardiovasc Res (2002) 1.27
In vivo two-photon excited fluorescence microscopy reveals cardiac- and respiration-dependent pulsatile blood flow in cortical blood vessels in mice. Am J Physiol Heart Circ Physiol (2012) 1.23
Platelet-derived growth factor stimulates LAT1 gene expression in vascular smooth muscle: role in cell growth. FASEB J (2004) 1.20
Endoplasmic reticulum stress stimulates heme oxygenase-1 gene expression in vascular smooth muscle. Role in cell survival. J Biol Chem (2004) 1.17
Regulation of homocysteine metabolism and methylation in human and mouse tissues. FASEB J (2010) 1.10
YC-1-mediated vascular protection through inhibition of smooth muscle cell proliferation and platelet function. Biochem Biophys Res Commun (2002) 1.02
Physiologic cyclic stretch inhibits apoptosis in vascular endothelium. FEBS Lett (2003) 0.98
Differential regulation of homocysteine transport in vascular endothelial and smooth muscle cells. Arterioscler Thromb Vasc Biol (2007) 0.91
Genetic and acquired determinants of individual variability of response to antiplatelet drugs. Circulation (2003) 0.86
Antiapoptotic action of carbon monoxide on cultured vascular smooth muscle cells. Exp Biol Med (Maywood) (2003) 0.83
The cyclic GMP modulators YC-1 and zaprinast reduce vessel remodeling through antiproliferative and proapoptotic effects. J Cardiovasc Pharmacol Ther (2009) 0.80
Translating basic discoveries into better health care: the APM's recommendations for improving translational research. Am J Med (2004) 0.78
Cyclic strain stimulates L-proline transport in vascular smooth muscle cells. Am J Hypertens (2004) 0.78
Optimizing initial therapy of acute venous thromboembolism. Thromb Haemost (2003) 0.75
Warfarin for venous thromboembolism - walking the dosing tightrope. N Engl J Med (2003) 0.75
The research community now and in the future: APM's recommendations for NIH priorities. Am J Med (2003) 0.75
Inhibition of plasminogen activator inhibitor-1 expression in vascular smooth muscle cells by protoporphyrins through a heme oxygenase-independent mechanism. Mol Cell Biochem (2008) 0.75