Published in Ann Rheum Dis on October 29, 2007
Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis. Arthritis Rheum (2013) 2.17
ANCA-associated vasculitides--advances in pathogenesis and treatment. Nat Rev Rheumatol (2010) 1.67
The contribution of genetic variation and infection to the pathogenesis of ANCA-associated systemic vasculitis. Arthritis Res Ther (2010) 1.20
Confirmation of the genetic association of CTLA4 and PTPN22 with ANCA-associated vasculitis. BMC Med Genet (2009) 0.90
Meta-analysis of genetic polymorphisms in granulomatosis with polyangiitis (Wegener's) reveals shared susceptibility loci with rheumatoid arthritis. Arthritis Rheum (2012) 0.85
The immunopathology of ANCA-associated vasculitis. Semin Immunopathol (2014) 0.83
Association of HLA genes with clinical outcomes of ANCA-associated vasculitis. Clin J Am Soc Nephrol (2012) 0.83
Genetically determined severity of anti-myeloperoxidase glomerulonephritis. Am J Pathol (2013) 0.83
Familial granulomatosis with polyangiitis: three cases of this rare disorder in one Indoasian family carrying an identical HLA DPB1 allele. BMJ Case Rep (2012) 0.81
[Update on granulomatosis with polyangitis (GPA, Wegener's granulomatosis)]. Z Rheumatol (2012) 0.81
Protective Role of HLA-DRB1*13:02 against Microscopic Polyangiitis and MPO-ANCA-Positive Vasculitides in a Japanese Population: A Case-Control Study. PLoS One (2016) 0.76
Genetic variability of RXRB, PPARA, and PPARG in Wegener's granulomatosis. PPAR Res (2009) 0.75
Genetic Susceptibility to ANCA-Associated Vasculitis: State of the Art. Front Immunol (2014) 0.75
[First genomewide association study of ANCA-associated vasculitis]. Z Rheumatol (2013) 0.75
Pathogenesis of ANCA-associated vasculitis. Rheum Dis Clin North Am (2010) 0.75
[The genetics of vasculitides]. Z Rheumatol (2011) 0.75
Nomenclature of systemic vasculitides. Proposal of an international consensus conference. Arthritis Rheum (1994) 14.16
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. Nat Genet (1998) 12.92
2012 revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides. Arthritis Rheum (2013) 11.18
EULAR recommendations for the management of primary small and medium vessel vasculitis. Ann Rheum Dis (2008) 4.88
Multiple Sclerosis Severity Score: using disability and disease duration to rate disease severity. Neurology (2005) 3.45
DNA finger printing by oligonucleotide probes specific for simple repeats. Hum Genet (1986) 3.41
Anti-neutrophil cytoplasm antibodies in Wegener's granulomatosis recognize an elastinolytic enzyme. J Exp Med (1990) 3.37
Anticytoplasmic autoantibodies: their immunodiagnostic value in Wegener granulomatosis. Ann Intern Med (1989) 3.33
An interdisciplinary approach to the care of patients with Wegener's granulomatosis: long-term outcome in 155 patients. Arthritis Rheum (2000) 3.06
Genetic and population study of a Y-linked tetranucleotide repeat DNA polymorphism with a simple non-isotopic technique. Hum Genet (1993) 2.70
Standardized neurologic evaluations of 128 patients with Wegener granulomatosis. Arch Neurol (2001) 2.69
The risk of tuberculosis related to tumour necrosis factor antagonist therapies: a TBNET consensus statement. Eur Respir J (2010) 2.56
Submicroscopic duplication in Xq28 causes increased expression of the MECP2 gene in a boy with severe mental retardation and features of Rett syndrome. J Med Genet (2005) 2.35
EULAR recommendations for the management of large vessel vasculitis. Ann Rheum Dis (2008) 2.25
DNA fingerprinting with the oligonucleotide probe (CAC)5/(GTG)5: somatic stability and germline mutations. Hum Genet (1989) 2.22
Anticytoplasmic antibodies in Wegener's granulomatosis. Lancet (1986) 2.12
Autoantibodies against cytoplasmic structures of neutrophil granulocytes in Wegener's granulomatosis. Clin Exp Immunol (1987) 2.09
Improved PCR conditions for the stretch of (CAG)n repeats causing Huntington's disease. Hum Mol Genet (1993) 2.02
Outcomes from studies of antineutrophil cytoplasm antibody associated vasculitis: a systematic review by the European League Against Rheumatism systemic vasculitis task force. Ann Rheum Dis (2007) 2.01
Improved differentiation between Churg-Strauss syndrome and Wegener's granulomatosis by an artificial neural network. Arthritis Rheum (2001) 2.00
Effectiveness of TNF-alpha blockade with infliximab in refractory Wegener's granulomatosis. Rheumatology (Oxford) (2002) 1.98
Elevated relapse rate under oral methotrexate versus leflunomide for maintenance of remission in Wegener's granulomatosis. Rheumatology (Oxford) (2007) 1.95
Simple repeat sequences on the human Y chromosome are equally polymorphic as their autosomal counterparts. Hum Genet (1992) 1.94
Optimized oligonucleotide probes for DNA fingerprinting. Electrophoresis (1988) 1.94
Myelin autoreactivity in multiple sclerosis: recognition of myelin basic protein in the context of HLA-DR2 products by T lymphocytes of multiple-sclerosis patients and healthy donors. Proc Natl Acad Sci U S A (1990) 1.93
Ataxia with oculomotor apraxia type 2: clinical, biological and genotype/phenotype correlation study of a cohort of 90 patients. Brain (2009) 1.91
Worldwide ethnic distribution of the G protein beta3 subunit 825T allele and its association with obesity in Caucasian, Chinese, and Black African individuals. J Am Soc Nephrol (1999) 1.76
Anti-neutrophil cytoplasmic antibodies engage and activate human neutrophils via Fc gamma RIIa. J Immunol (1994) 1.76
Increased susceptibility to sporadic Parkinson's disease by a certain combined alpha-synuclein/apolipoprotein E genotype. Ann Neurol (1999) 1.74
Expansion of a novel CAG trinucleotide repeat in the 5' region of PPP2R2B is associated with SCA12. Nat Genet (1999) 1.74
Suppression of experimentally induced autoimmune encephalomyelitis by cytolytic T-T cell interactions. Nature (1988) 1.71
Differentiation of species and strains among filamentous fungi by DNA fingerprinting. Curr Genet (1991) 1.65
Dominance of one T-cell receptor in the H-2Kb/TNP response. Nature (1987) 1.63
Activated neutrophils express proteinase 3 on their plasma membrane in vitro and in vivo. Clin Exp Immunol (1994) 1.61
Cyclosporin for acute dermatomyositis. Lancet (1984) 1.61
A new type of perinuclear anti-neutrophil cytoplasmic antibody (p-ANCA) in active ulcerative colitis but not in Crohn's disease. Immunobiology (1990) 1.60
Cytokine profiles in Wegener's granulomatosis: predominance of type 1 (Th1) in the granulomatous inflammation. Arthritis Rheum (1999) 1.59
Subacute bacterial endocarditis with positive cytoplasmic antineutrophil cytoplasmic antibodies and anti-proteinase 3 antibodies. Arthritis Rheum (2000) 1.57
Ultrastructural localization of proteinase 3, the target antigen of anti-cytoplasmic antibodies circulating in Wegener's granulomatosis. Am J Pathol (1990) 1.57
Association of inflammatory bowel disease risk loci with sarcoidosis, and its acute and chronic subphenotypes. Eur Respir J (2010) 1.55
Geographic differences in the allele frequencies of the human Y-linked tetranucleotide polymorphism DYS19. Hum Genet (1996) 1.52
Giant cell arteritis is more prevalent in urban than in rural populations: results of an epidemiological study of primary systemic vasculitides in Germany. Rheumatology (Oxford) (2000) 1.52
Development and validation of a disease extent index for Wegener's granulomatosis. Clin Nephrol (2001) 1.51
Influence of disease manifestation and antineutrophil cytoplasmic antibody titer on the response to pulse cyclophosphamide therapy in patients with Wegener's granulomatosis. Arthritis Rheum (1994) 1.51
DNA fingerprinting using non-radioactive oligonucleotide probes specific for simple repeats. Nucleic Acids Res (1988) 1.47
Base sequence of a cloned snake W-chromosome DNA fragment and identification of a male-specific putative mRNA in the mouse. Proc Natl Acad Sci U S A (1982) 1.46
Elevated serum levels of soluble interleukin-2 receptor in patients with Wegener's granulomatosis. Association with disease activity. Arthritis Rheum (1992) 1.44
(CAC)5, a very informative oligonucleotide probe for DNA fingerprinting. Nucleic Acids Res (1988) 1.43
Wegener's granulomatosis associated with renal cell carcinoma. Arthritis Rheum (1999) 1.42
Head and neck manifestations of Wegener's granulomatosis. Rhinology (2006) 1.41
Detection of somatic changes in human renal cell carcinomas with oligonucleotide probes specific for simple repeat motifs. Genes Chromosomes Cancer (1993) 1.40
Costimulatory molecules in Wegener's granulomatosis (WG): lack of expression of CD28 and preferential up-regulation of its ligands B7-1 (CD80) and B7-2 (CD86) on T cells. Clin Exp Immunol (1998) 1.39
Exonic polymorphism vs intronic simple repeat hypervariability in MHC-DRB genes. Immunogenetics (1992) 1.39
[The risk profile of low-dose methotrexate in the therapy of chronic polyarthritis]. Dtsch Med Wochenschr (1992) 1.39
Polymorphic simple GATA/GACA repeats in plant genomes. Nucleic Acids Res (1989) 1.38
Mutation analysis of the spastin gene (SPG4) in patients in Germany with autosomal dominant hereditary spastic paraplegia. Hum Mutat (2002) 1.38
Lack of association between antiphospholipid antibodies and thrombocytopenia in patients with Wegener's granulomatosis. Semin Arthritis Rheum (2001) 1.38
Treatment of Wegener's granulomatosis: the view from two non-nephrologists. Nephrol Dial Transplant (1994) 1.38
The leucotriene receptor antagonist montelukast and the risk of Churg-Strauss syndrome: a case-crossover study. Thorax (2008) 1.35
TAP deficiency syndrome. Clin Exp Immunol (2000) 1.35
Association of multiple sclerosis with ILT6 deficiency. Genes Immun (2005) 1.34
Lack of efficacy of rituximab in Wegener's granulomatosis with refractory granulomatous manifestations. Ann Rheum Dis (2005) 1.33
Detection and quantitation of anti-neutrophil cytoplasm antibodies in Wegener's granulomatosis by ELISA using affinity-purified antigen. J Immunol Methods (1988) 1.33
The registry of the German Network for Systemic Scleroderma: frequency of disease subsets and patterns of organ involvement. Rheumatology (Oxford) (2008) 1.32
Cryoglobulinemic vasculitis. Arthritis Rheum (1999) 1.31
[Antineutrophilic cytoplasmic antibodies (ANCA) in inflammatory rheumatic diseases: immunodiagnostic and immunopathogenetic aspects]. Z Rheumatol (1995) 1.31
Wegener's autoantigen decoded. Nature (1990) 1.31
Genetic association studies of bronchial asthma--a need for Bonferroni correction? Hum Genet (2000) 1.31
Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn's disease. Gut (2005) 1.30
Autosomal dominant cerebellar ataxia: phenotypic differences in genetically defined subtypes? Ann Neurol (1997) 1.29
A polymorphism in the CD14 gene is associated with Crohn disease. Scand J Gastroenterol (2002) 1.28
CD28 negative T cells are enriched in granulomatous lesions of the respiratory tract in Wegener's granulomatosis. Thorax (2001) 1.24
Cytomegalovirus infection in systemic necrotizing vasculitis: causative agent or opportunistic infection? Rheumatol Int (2000) 1.24
Differential stability of the (GAA)n tract in the Friedreich ataxia (STM7) gene. Hum Genet (1997) 1.22
The organization of the evolutionarily conserved GATA/GACA repeats in the mouse genome. Chromosoma (1986) 1.20
Friedreich's ataxia. Revision of the phenotype according to molecular genetics. Brain (1997) 1.19
Trinucleotide expansion within the MJD1 gene presents clinically as spinocerebellar ataxia and occurs most frequently in German SCA patients. Hum Mol Genet (1995) 1.19
Blount disease (tibia vara): another skeletal disorder associated with childhood obesity. J Pediatr (1982) 1.19
The primitive code and repeats of base oligomers as the primordial protein-encoding sequence. Proc Natl Acad Sci U S A (1983) 1.19
Correlation between HRCT findings, pulmonary function tests and bronchoalveolar lavage cytology in interstitial lung disease associated with rheumatoid arthritis. Eur Radiol (2003) 1.19
Transforming growth factor-beta and suppression of humoral immune responses in HIV infection. J Clin Invest (1991) 1.18
Human endothelial cells express proteinase 3, the target antigen of anticytoplasmic antibodies in Wegener's granulomatosis. Blood (1993) 1.18
Refined mapping of the epilepsy susceptibility locus EJM1 on chromosome 6. Neurology (1997) 1.18
Efficacy of transbronchial biopsy in pulmonary vaculitides. Eur Respir J (1997) 1.18
Increased frequency of migraine in narcoleptic patients: a confirmatory study. Cephalalgia (2003) 1.17
An isoform of ataxin-3 accumulates in the nucleus of neuronal cells in affected brain regions of SCA3 patients. Brain Pathol (1998) 1.17
Severe CNS manifestations as the clinical hallmark in generalized Wegener's granulomatosis consistently negative for antineutrophil cytoplasmic antibodies (ANCA). A report of 3 cases and a review of the literature. Clin Exp Rheumatol (2001) 1.17
Expansion of the (CAG)n repeat causing Huntington's disease in 352 patients of German origin. Hum Mol Genet (1993) 1.16
Inhibitors in the NFkappaB cascade comprise prime candidate genes predisposing to multiple sclerosis, especially in selected combinations. Genes Immun (2002) 1.16
Promoter polymorphism rs3087456 in the MHC class II transactivator gene is not associated with susceptibility for selected autoimmune diseases in German patient groups. Int J Immunogenet (2006) 1.16