Published in Molecules on October 10, 2007
Structural and thermodynamic studies of the interaction of distamycin A with the parallel quadruplex structure [d(TGGGGT)]4. J Am Chem Soc (2007) 1.05
Pyrazolo[3,4-d]pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylation. J Med Chem (2006) 1.05
The G-triplex DNA. Angew Chem Int Ed Engl (2013) 1.04
Antioxidant and free radical scavenging activity of flavonol glycosides from different Aconitum species. J Ethnopharmacol (2003) 0.97
Increasing the X-ray diffraction power of protein crystals by dehydration: the case of bovine serum albumin and a survey of literature data. Int J Mol Sci (2012) 0.97
Applications of isothermal titration calorimetry in biophysical studies of G-quadruplexes. Int J Mol Sci (2009) 0.97
The enhancement of antiproliferative and proapoptotic activity of HDAC inhibitors by curcumin is mediated by Hsp90 inhibition. Cell Mol Life Sci (2009) 0.96
Targeting G-quadruplex structure in the human c-Kit promoter with short PNA sequences. Bioconjug Chem (2011) 0.95
Synthesis and 3D QSAR of new pyrazolo[3,4-b]pyridines: potent and selective inhibitors of A1 adenosine receptors. J Med Chem (2005) 0.95
Antimicrobial diterpenes from the seeds of Cephalotaxus harringtonia var. drupacea. Planta Med (2003) 0.95
Shedding light on the interaction between TMPyP4 and human telomeric quadruplexes. J Phys Chem B (2009) 0.95
Structural and conformational requisites in DNA quadruplex groove binding: another piece to the puzzle. J Am Chem Soc (2010) 0.95
The identification of a novel natural activator of p300 histone acetyltranferase provides new insights into the modulation mechanism of this enzyme. Chembiochem (2010) 0.94
Structure-based optimization of pyrazolo[3,4-d]pyrimidines as Abl inhibitors and antiproliferative agents toward human leukemia cell lines. J Med Chem (2008) 0.93
Pyrazolo[3,4-d]pyrimidines endowed with antiproliferative activity on ductal infiltrating carcinoma cells. J Med Chem (2004) 0.92
Salvinorin A exerts opposite presynaptic controls on neurotransmitter exocytosis from mouse brain nerve terminals. Neuropharmacology (2009) 0.91
Study of flavonoids of Sechium edule (Jacq) Swartz (Cucurbitaceae) different edible organs by liquid chromatography photodiode array mass spectrometry. J Agric Food Chem (2004) 0.90
Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis. Nucleic Acids Res (2013) 0.90
Thermodynamics and kinetics of PNA-DNA quadruplex-forming chimeras. J Am Chem Soc (2005) 0.89
Natural and semisynthetic azaphilones as a new scaffold for Hsp90 inhibitors. Bioorg Med Chem (2010) 0.89
Antimicrobial activity of the ornamental species Salvia corrugata, a potential new crop for extractive purposes. J Agric Food Chem (2008) 0.88
Chemical biology of histone acetyltransferase natural compounds modulators. Mol Divers (2011) 0.88
Pregnane glycosides from Leptadenia pyrotechnica. J Nat Prod (2006) 0.87
Identification of a novel pyrazolo[3,4-d]pyrimidine able to inhibit cell proliferation of a human osteogenic sarcoma in vitro and in a xenograft model in mice. J Med Chem (2007) 0.87
Antioxidant and free-radical scavenging activity of constituents of the leaves of Tachigalia paniculata. J Nat Prod (2002) 0.86
Sesterterpenes as tubulin tyrosine ligase inhibitors. First insight of structure-activity relationships and discovery of new lead. J Med Chem (2009) 0.86
Synthesis, biological evaluation and docking studies of 4-amino substituted 1H-pyrazolo[3,4-d]pyrimidines. Eur J Med Chem (2008) 0.86
Chemical proteomics reveals HSP70 1A as a target for the anticancer diterpene oridonin in Jurkat cells. J Proteomics (2013) 0.85
Shooting for selective druglike G-quadruplex binders: evidence for telomeric DNA damage and tumor cell death. J Med Chem (2012) 0.85
New 1,3,4-thiadiazole derivatives endowed with analgesic and anti-inflammatory activities. Bioorg Med Chem (2005) 0.85
Studying the effect of crowding and dehydration on DNA G-quadruplexes. Methods (2012) 0.85
Antiproliferative activity of new 1-aryl-4-amino-1H-pyrazolo[3,4-d]pyrimidine derivatives toward the human epidermoid carcinoma A431 cell line. Eur J Med Chem (2004) 0.84
Tritoniopsins A-D, cladiellane-based diterpenes from the South China Sea nudibranch Tritoniopsis elegans and its prey Cladiella krempfi. J Nat Prod (2011) 0.84
Mutants of the tumour suppressor p53 L1 loop as second-site suppressors for restoring DNA binding to oncogenic p53 mutations: structural and biochemical insights. Biochem J (2010) 0.84
Relative stability of quadruplexes containing different number of G-tetrads. Nucleosides Nucleotides Nucleic Acids (2005) 0.84
New selective phosphodiesterase 4D inhibitors differently acting on long, short, and supershort isoforms. J Med Chem (2009) 0.83
Exploring the chemical space of G-quadruplex binders: discovery of a novel chemotype targeting the human telomeric sequence. J Med Chem (2013) 0.83
Antioxidant chalcone glycosides and flavanones from Maclura (Chlorophora) tinctoria. J Nat Prod (2003) 0.83
Further constituents from Caralluma negevensis. Phytochemistry (2003) 0.82
Secondary metabolite profile in induced tetraploids of wild Solanum commersonii Dun. Chem Biodivers (2011) 0.82
Chemical composition and antioxidant activity of phenolic compounds from wild and cultivated Sclerocarya birrea(Anacardiaceae) leaves. J Agric Food Chem (2003) 0.82
New pregnane glycosides from Caralluma dalzielii. Steroids (2005) 0.82
Flavonoid characterization and in vitro antioxidant activity of Aconitum anthora L. (Ranunculaceae). Phytochemistry (2008) 0.81
Phytotoxic clerodane diterpenes from Salvia miniata Fernald (Lamiaceae). Phytochemistry (2010) 0.81
Fluorescence enhancement upon G-quadruplex folding: synthesis, structure, and biophysical characterization of a dansyl/cyclodextrin-tagged thrombin binding aptamer. Bioconjug Chem (2013) 0.81
Oleanane saponins from Stylosanthes erecta. J Nat Prod (2007) 0.81
Bioassay-guided isolation of proanthocyanidins with antiangiogenic activities. J Nat Prod (2012) 0.81
Triterpenoid saponins from Pteleopsis suberosa stem bark. Phytochemistry (2006) 0.81
Phosphodiesterase isoform-specific expression induced by traumatic brain injury. J Neurochem (2012) 0.81
Inhibition of the thioredoxin system is a basis for the antileukemic potential of 13-hydroxy-15-oxo-zoapatlin. Free Radic Biol Med (2008) 0.81
Structure of kaurane-type diterpenes from Parinari sprucei and their potential anticancer activity. Planta Med (2004) 0.81
Application of "magnetic tongue" to the sensory evaluation of extra virgin olive oil. Food Chem (2012) 0.81
Homology modeling, docking studies and molecular dynamic simulations using graphical processing unit architecture to probe the type-11 phosphodiesterase catalytic site: a computational approach for the rational design of selective inhibitors. Chem Biol Drug Des (2013) 0.81
A chemical proteomics approach reveals Hsp27 as a target for proapoptotic clerodane diterpenes. Mol Biosyst (2012) 0.80
Substituted pyrazolo[3,4-b]pyridines as potent A1 adenosine antagonists: synthesis, biological evaluation, and development of an A1 bovine receptor model. ChemMedChem (2008) 0.80
Antiproliferative cardenolides from Periploca graeca. Planta Med (2007) 0.80
Thioredoxin system modulation by plant and fungal secondary metabolites. Curr Med Chem (2010) 0.80
Design, synthesis, biophysical and biological studies of trisubstituted naphthalimides as G-quadruplex ligands. Bioorg Med Chem (2011) 0.80
Competitive ELISA-based screening of plant derivatives for the inhibition of VEGF family members interaction with vascular endothelial growth factor receptor 1. Planta Med (2008) 0.80
The biflavonoid amentoflavone inhibits neovascularization preventing the activity of proangiogenic vascular endothelial growth factors. J Biol Chem (2011) 0.79
A novel mechanism for cyclic adenosine monophosphate-mediated memory formation: Role of amyloid beta. Ann Neurol (2014) 0.79
G-quadruplex on oligo affinity support (G4-OAS): an easy affinity chromatography-based assay for the screening of G-quadruplex ligands. Anal Chem (2014) 0.79
Phenolic compounds from Baseonema acuminatum leaves: isolation and antimicrobial activity. Planta Med (2004) 0.79
Antiproliferative triterpene saponins from Entada africana. J Nat Prod (2006) 0.79
Total phenolic content and antioxidant activity of Salvia spp. exudates. Nat Prod Commun (2012) 0.79
Toward an antitumor form of bovine pancreatic ribonuclease: the crystal structure of three noncovalent dimeric mutants. Biopolymers (2009) 0.79
New flavonoid glycosides from Vernonia ferruginea. Nat Prod Commun (2009) 0.79
A chemical-biological study reveals C9-type iridoids as novel heat shock protein 90 (Hsp90) inhibitors. J Med Chem (2013) 0.79
Thermodynamic signature of secondary nano-emulsion formation by isothermal titration calorimetry. Langmuir (2014) 0.79
Cross-talk between prion protein and quadruplex-forming nucleic acids: a dynamic complex formation. Nucleic Acids Res (2012) 0.78
In silico phosphorylation of the autoinhibited form of p47(phox): insights into the mechanism of activation. Biophys J (2010) 0.78
Synthesis, molecular modeling studies, and pharmacological activity of selective A(1) receptor antagonists. J Med Chem (2002) 0.78
Cytotoxic saponins from Schefflera rotundifolia. Planta Med (2004) 0.78
Natural iminosugar (+)-lentiginosine inhibits ATPase and chaperone activity of hsp90. PLoS One (2012) 0.78
Demethyl fruticulin A (SCO-1) causes apoptosis by inducing reactive oxygen species in mitochondria. J Cell Biochem (2010) 0.78
Pro-apoptotic and cytostatic activity of naturally occurring cardenolides. Cancer Chemother Pharmacol (2009) 0.78
Cytotoxic saponins from Schefflera fagueti. Planta Med (2003) 0.78
Anti-angiogenic activity of Entada africana root. Nat Prod Res (2014) 0.78
Energetics of ligand binding to G-quadruplexes. Top Curr Chem (2013) 0.78
6-amino-4-oxo-1,3-diphenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carbonyl derivatives as a new class of potent inhibitors of Interleukin-8-induced neutrophil chemotaxis. Bioorg Med Chem (2009) 0.78
3D QSAR models built on structure-based alignments of Abl tyrosine kinase inhibitors. ChemMedChem (2009) 0.77
Synthesis of 1-(2-chloro-2-phenylethyl)-6-methylthio-1H-pyrazolo[3,4-d]pyrimidines 4-amino substituted and their biological evaluation. Eur J Med Chem (2004) 0.77
Structure and absolute configuration of new diterpenes from Lavandula multifida. J Nat Prod (2002) 0.77
Docking-based CoMFA and CoMSIA analyses of tetrahydro-β-carboline derivatives as type-5 phosphodiesterase inhibitors. J Enzyme Inhib Med Chem (2011) 0.77
Effects of subacute treatment with benzopyranopyrimidines in hemostasis and experimental thrombosis in mice. Life Sci (2004) 0.77
2-aryl-3-phenylamino-4,5-dihydro-2h-benz[g]indazoles with analgesic activity. Farmaco (2003) 0.77
Triterpene derivatives as inhibitors of protein involved in the inflammatory process: molecules interfering with phospholipase A2, cycloxygenase, and lipoxygenase. Curr Drug Targets (2011) 0.77
The triazatruxene derivative azatrux binds to the parallel form of the human telomeric G-quadruplex under molecular crowding conditions: biophysical and molecular modeling studies. Biochimie (2011) 0.77
Noncanonical DNA secondary structures as drug targets: the prospect of the i-motif. ChemMedChem (2014) 0.77
Medicinal Plants Used in Mali for the Treatment of Malaria and Liver Diseases. Nat Prod Commun (2016) 0.77
Steroids with anti-inflammatory activity from Vernonia nigritiana Oliv. & Hiern. Phytochemistry (2013) 0.76
Conformational stability and DNA binding energetics of the rat thyroid transcription factor 1 homeodomain. Proteins (2008) 0.76
13-Hydroxy-15-oxo-zoapatlin, an ent-kaurane diterpene, induces apoptosis in human leukemia cells, affecting thiol-mediated redox regulation. Free Radic Biol Med (2007) 0.76
Shading the TRF2 recruiting function: a new horizon in drug development. J Am Chem Soc (2014) 0.76