Published in Nat Rev Neurosci on December 01, 2007
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Interactions of alkali cations with glutamate transporters. Philos Trans R Soc Lond B Biol Sci (2009) 1.22
Thinking outside the cleft to understand synaptic activity: contribution of the cystine-glutamate antiporter (System xc-) to normal and pathological glutamatergic signaling. Pharmacol Rev (2012) 1.21
Proteomic snapshot of the EGF-induced ubiquitin network. Mol Syst Biol (2011) 1.19
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Ionic storm in hypoxic/ischemic stress: can opioid receptors subside it? Prog Neurobiol (2009) 1.18
Increased extracellular glutamate in the nucleus accumbens promotes excessive ethanol drinking in ethanol dependent mice. Neuropsychopharmacology (2013) 1.17
Increased susceptibility to cortical spreading depression in the mouse model of familial hemiplegic migraine type 2. PLoS Genet (2011) 1.16
Neuronal hyperactivity recruits microglial processes via neuronal NMDA receptors and microglial P2Y12 receptors after status epilepticus. J Neurosci (2014) 1.15
Glutamate transporters and the excitotoxic path to motor neuron degeneration in amyotrophic lateral sclerosis. Antioxid Redox Signal (2009) 1.14
Review. The molecular logic of sodium-coupled neurotransmitter transporters. Philos Trans R Soc Lond B Biol Sci (2009) 1.13
Abnormal glycosylation of EAAT1 and EAAT2 in prefrontal cortex of elderly patients with schizophrenia. Schizophr Res (2009) 1.12
Glial cells in neuronal network function. Philos Trans R Soc Lond B Biol Sci (2010) 1.09
Protein kinase C (PKC)-promoted endocytosis of glutamate transporter GLT-1 requires ubiquitin ligase Nedd4-2-dependent ubiquitination but not phosphorylation. J Biol Chem (2012) 1.06
GABA and Glutamate Transporters in Brain. Front Endocrinol (Lausanne) (2013) 1.06
Loss of glial glutamate and aspartate transporter (excitatory amino acid transporter 1) causes locomotor hyperactivity and exaggerated responses to psychotomimetics: rescue by haloperidol and metabotropic glutamate 2/3 agonist. Biol Psychiatry (2008) 1.04
Aquaporin-4 deficiency impairs synaptic plasticity and associative fear memory in the lateral amygdala: involvement of downregulation of glutamate transporter-1 expression. Neuropsychopharmacology (2012) 1.02
The relative roles of diffusion and uptake in clearing synaptically released glutamate change during early postnatal development. J Neurosci (2011) 1.02
Synaptic activity and bioenergy homeostasis: implications in brain trauma and neurodegenerative diseases. Front Neurol (2013) 1.02
Alcohol drinking and deprivation alter basal extracellular glutamate concentrations and clearance in the mesolimbic system of alcohol-preferring (P) rats. Addict Biol (2012) 1.02
Neuronal activity regulates glutamate transporter dynamics in developing astrocytes. Glia (2011) 1.01
A glial variant of the vesicular monoamine transporter is required to store histamine in the Drosophila visual system. PLoS Genet (2008) 1.01
Development of glutamatergic synaptic transmission in binaural auditory neurons. J Neurophysiol (2010) 1.01
Increased coupling and altered glutamate transport currents in astrocytes following kainic-acid-induced status epilepticus. Neurobiol Dis (2010) 1.00
Astroglial FMRP-dependent translational down-regulation of mGluR5 underlies glutamate transporter GLT1 dysregulation in the fragile X mouse. Hum Mol Genet (2013) 0.99
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How do astrocytes shape synaptic transmission? Insights from electrophysiology. Front Cell Neurosci (2013) 0.98
Glutamate as a neurotransmitter in the healthy brain. J Neural Transm (Vienna) (2014) 0.97
Impact of synaptic neurotransmitter concentration time course on the kinetics and pharmacological modulation of inhibitory synaptic currents. Front Cell Neurosci (2011) 0.96
Synaptically induced sodium signals in hippocampal astrocytes in situ. J Physiol (2009) 0.96
Plasticity in glutamatergic NTS neurotransmission. Respir Physiol Neurobiol (2008) 0.95
Neuroinflammation in the normal aging hippocampus. Neuroscience (2015) 0.95
The trinity of Ca2+ sources for the exocytotic glutamate release from astrocytes. Neurochem Int (2009) 0.94
Conditional deletion of the glutamate transporter GLT-1 reveals that astrocytic GLT-1 protects against fatal epilepsy while neuronal GLT-1 contributes significantly to glutamate uptake into synaptosomes. J Neurosci (2015) 0.93
Dynamic functions of GABA signaling during granule cell maturation. Front Neural Circuits (2013) 0.92
Glutamate transporters EAAT4 and EAAT5 are expressed in vestibular hair cells and calyx endings. PLoS One (2012) 0.92
Enhanced antinociceptive response to intracerebroventricular kyotorphin in Pept2 null mice. J Neurochem (2009) 0.92
Update on the neurobiology of schizophrenia: a role for extracellular microdomains. Minerva Psichiatr (2012) 0.91
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GLT-1 loss accelerates cognitive deficit onset in an Alzheimer's disease animal model. J Alzheimers Dis (2011) 0.91
Accelerated experience-dependent pruning of cortical synapses in ephrin-A2 knockout mice. Neuron (2013) 0.90
The computational power of astrocyte mediated synaptic plasticity. Front Comput Neurosci (2012) 0.89
Systematic regional variations in Purkinje cell spiking patterns. PLoS One (2014) 0.89
Corticostriatal circuit dysfunction in Huntington's disease: intersection of glutamate, dopamine and calcium. Future Neurol (2010) 0.89
Peripheral nerve injury produces a sustained shift in the balance between glutamate release and uptake in the dorsal horn of the spinal cord. Pain (2012) 0.89
Antagonistic interaction between adenosine A2A receptors and Na+/K+-ATPase-α2 controlling glutamate uptake in astrocytes. J Neurosci (2013) 0.89
VGluT1+ neuronal glutamatergic signaling regulates postnatal developmental maturation of cortical protoplasmic astroglia. J Neurosci (2014) 0.88
Glutamate signaling in healthy and diseased bone. Front Endocrinol (Lausanne) (2012) 0.88
Motor neuron impairment mediated by a sumoylated fragment of the glial glutamate transporter EAAT2. Glia (2011) 0.88
Relationship between increase in astrocytic GLT-1 glutamate transport and late-LTP. Learn Mem (2012) 0.86
Synaptic homeostasis in a zebrafish glial glycine transporter mutant. J Neurophysiol (2008) 0.86
Astroglial glutamate transporters coordinate excitatory signaling and brain energetics. Neurochem Int (2016) 0.86
Abnormal expression of glutamate transporters in temporal lobe areas in elderly patients with schizophrenia. Schizophr Res (2013) 0.86
Abnormal partitioning of hexokinase 1 suggests disruption of a glutamate transport protein complex in schizophrenia. Schizophr Res (2014) 0.86
Impaired glutamate recycling and GluN2B-mediated neuronal calcium overload in mice lacking TGF-β1 in the CNS. Glia (2013) 0.85
Extrasynaptic targeting of NMDA receptors following D1 dopamine receptor activation and cocaine self-administration. J Neurosci (2013) 0.85
Astroglial connexin 43 sustains glutamatergic synaptic efficacy. Philos Trans R Soc Lond B Biol Sci (2014) 0.85
Reduction of EEG theta power and changes in motor activity in rats treated with ceftriaxone. PLoS One (2012) 0.85
GLT-1 Promoter Activity in Astrocytes and Neurons of Mouse Hippocampus and Somatic Sensory Cortex. Front Neuroanat (2010) 0.85
Contributions of astrocytes to epileptogenesis following status epilepticus: opportunities for preventive therapy? Neurochem Int (2012) 0.85
Hyperactivation of the habenula as a link between depression and sleep disturbance. Front Hum Neurosci (2013) 0.85
Morphological plasticity of astroglia: Understanding synaptic microenvironment. Glia (2015) 0.84
Neuronal glutamate transporters regulate glial excitatory transmission. J Neurosci (2012) 0.84
Age-related severity of focal ischemia in female rats is associated with impaired astrocyte function. Neurobiol Aging (2011) 0.84
Activation of extrasynaptic NMDARs at individual parallel fiber-molecular layer interneuron synapses in cerebellum. J Neurosci (2013) 0.84
Cellular and Synaptic Localization of EAAT2a in Human Cerebral Cortex. Front Neuroanat (2011) 0.84
Glutamate transporter-mediated glutamate secretion in the mammalian pineal gland. J Neurosci (2008) 0.84
The potential therapeutic effect of guanosine after cortical focal ischemia in rats. PLoS One (2014) 0.83
Inhibition of System Xc(-) Transporter Attenuates Autoimmune Inflammatory Demyelination. J Immunol (2015) 0.83
Death Associated Protein Kinase (DAPK) -mediated neurodegenerative mechanisms in nematode excitotoxicity. BMC Neurosci (2015) 0.82
Proteome analysis and conditional deletion of the EAAT2 glutamate transporter provide evidence against a role of EAAT2 in pancreatic insulin secretion in mice. J Biol Chem (2013) 0.82
Expression of EAAT2 in neurons and protoplasmic astrocytes during human cortical development. J Comp Neurol (2012) 0.82
The ubiquitous nature of multivesicular release. Trends Neurosci (2015) 0.82
Physical and functional interaction of NCX1 and EAAC1 transporters leading to glutamate-enhanced ATP production in brain mitochondria. PLoS One (2012) 0.81
Isoforms of the neuronal glutamate transporter gene, SLC1A1/EAAC1, negatively modulate glutamate uptake: relevance to obsessive-compulsive disorder. Transl Psychiatry (2013) 0.81
Engineering the glutamate transporter homologue GltPh using protein semisynthesis. Biochemistry (2015) 0.81
Localization of excitatory amino acid transporters EAAT1 and EAAT2 in human postmortem cortex: a light and electron microscopic study. Neuroscience (2014) 0.81
Low Affinity and Slow Na+ Binding Precedes High Affinity Aspartate Binding in the Secondary-active Transporter GltPh. J Biol Chem (2015) 0.81
Molecular approaches for manipulating astrocytic signaling in vivo. Front Cell Neurosci (2015) 0.81
An association between the reduced levels of SLC1A2 and GAD1 in the dorsolateral prefrontal cortex in major depressive disorder: possible involvement of an attenuated RAF/MEK/ERK signaling pathway. J Neural Transm (Vienna) (2014) 0.80
The mGluR2/3 agonist LY379268 blocks the effects of GLT-1 upregulation on prepulse inhibition of the startle reflex in adult rats. Neuropsychopharmacology (2010) 0.80
Control of cleft glutamate concentration and glutamate spill-out by perisynaptic glia: uptake and diffusion barriers. PLoS One (2013) 0.80
Effects of cocaine and withdrawal on the mouse nucleus accumbens transcriptome. Genes Brain Behav (2012) 0.80
Metabotropic glutamate receptors and glutamate transporters shape transmission at the developing retinogeniculate synapse. J Neurophysiol (2012) 0.80
Estimating the synaptic current in a multiconductance AMPA receptor model. Biophys J (2011) 0.80
Up-regulation of GLT1 reverses the deficit in cortically evoked striatal ascorbate efflux in the R6/2 mouse model of Huntington's disease. J Neurochem (2012) 0.80
Input-specific GABAergic signaling to newborn neurons in adult dentate gyrus. J Neurosci (2009) 1.33
Retroinhibition of presynaptic Ca2+ currents by endocannabinoids released via postsynaptic mGluR activation at a calyx synapse. J Neurosci (2004) 1.15
Ivy/neurogliaform interneurons coordinate activity in the neurogenic niche. Nat Neurosci (2011) 1.08
Distinct determinants of sparse activation during granule cell maturation. J Neurosci (2013) 1.01
GABA depolarization is required for experience-dependent synapse unsilencing in adult-born neurons. J Neurosci (2013) 1.00
Spillover-mediated feedforward inhibition functionally segregates interneuron activity. Neuron (2013) 0.99
Hilar mossy cells provide the first glutamatergic synapses to adult-born dentate granule cells. J Neurosci (2014) 0.94
Desynchronization of multivesicular release enhances Purkinje cell output. Neuron (2011) 0.91
Neuronal glutamate transporters regulate glial excitatory transmission. J Neurosci (2012) 0.84
Long-distance signaling via presynaptic glutamate transporters. Nat Neurosci (2006) 0.75
The contribution of extrasynaptic signaling to cerebellar information processing. Cerebellum (2014) 0.75