Published in Circ Res on November 08, 2007
Hydrogen sulfide as a gasotransmitter. J Neurochem (2010) 2.30
Cellular stress responses, the hormesis paradigm, and vitagenes: novel targets for therapeutic intervention in neurodegenerative disorders. Antioxid Redox Signal (2010) 1.77
Carbon monoxide as an endogenous vascular modulator. Am J Physiol Heart Circ Physiol (2011) 1.23
Regulation of haeme oxygenase-1 for treatment of neuroinflammation and brain disorders. Br J Pharmacol (2008) 1.14
Potassium channels and neurovascular coupling. Circ J (2010) 1.04
The locus coeruleus-norepinephrine network optimizes coupling of cerebral blood volume with oxygen demand. J Cereb Blood Flow Metab (2012) 1.03
Vasodilator signals from perivascular adipose tissue. Br J Pharmacol (2012) 1.03
Multifunctional role of astrocytes as gatekeepers of neuronal energy supply. Front Cell Neurosci (2013) 1.00
Hydrogen sulfide activates Ca²⁺ sparks to induce cerebral arteriole dilatation. J Physiol (2012) 1.00
Carbon monoxide: an emerging regulator of ion channels. J Physiol (2011) 0.91
Glutamate-induced calcium signals stimulate CO production in piglet astrocytes. Am J Physiol Heart Circ Physiol (2011) 0.88
Epoxyeicosatrienoic acid-dependent cerebral vasodilation evoked by metabotropic glutamate receptor activation in vivo. Am J Physiol Heart Circ Physiol (2011) 0.87
Neurovascular signaling in the brain and the pathological consequences of hypertension. Am J Physiol Heart Circ Physiol (2013) 0.86
Activation of astroglial calcium signaling by endogenous metabolites succinate and gamma-hydroxybutyrate in the nucleus accumbens. Front Neuroenergetics (2011) 0.84
Role of heme oxygenase-2 in pial arteriolar response to acetylcholine in mice with and without transfusion of cell-free hemoglobin polymers. Am J Physiol Regul Integr Comp Physiol (2008) 0.84
Glutamate regulates Ca2+ signals in smooth muscle cells of newborn piglet brain slice arterioles through astrocyte- and heme oxygenase-dependent mechanisms. Am J Physiol Heart Circ Physiol (2009) 0.83
Roles of glia limitans astrocytes and carbon monoxide in adenosine diphosphate-induced pial arteriolar dilation in newborn pigs. Stroke (2009) 0.83
Bidirectional neuro-glial signaling modalities in the hypothalamus: role in neurohumoral regulation. Auton Neurosci (2013) 0.81
Cell-to-cell communication and vascular dementia. Microcirculation (2012) 0.77
Cerebral artery signal transduction mechanisms: developmental changes in dynamics and Ca2+ sensitivity. Curr Vasc Pharmacol (2013) 0.77
Custom astrocyte-mediated vasomotor responses to neuronal energy demand. Genome Biol (2009) 0.77
Arachidonic acid- and prostaglandin E2-induced cerebral vasodilation is mediated by carbon monoxide, independent of reactive oxygen species in piglets. Am J Physiol Heart Circ Physiol (2011) 0.75
Potassium Channels in Regulation of Vascular Smooth Muscle Contraction and Growth. Adv Pharmacol (2016) 0.75
Neurovascular regulation in the normal brain and in Alzheimer's disease. Nat Rev Neurosci (2004) 9.29
Neuron-to-astrocyte signaling is central to the dynamic control of brain microcirculation. Nat Neurosci (2003) 8.23
The heme oxygenase system: a regulator of second messenger gases. Annu Rev Pharmacol Toxicol (1997) 7.50
Astrocyte-mediated control of cerebral blood flow. Nat Neurosci (2005) 6.90
Astrocytic purinergic signaling coordinates synaptic networks. Science (2005) 6.55
Astrocyte control of synaptic transmission and neurovascular coupling. Physiol Rev (2006) 5.46
GLIA: listening and talking to the synapse. Nat Rev Neurosci (2001) 4.67
Prostaglandins stimulate calcium-dependent glutamate release in astrocytes. Nature (1998) 4.03
Local potassium signaling couples neuronal activity to vasodilation in the brain. Nat Neurosci (2006) 3.27
Glial cells dilate and constrict blood vessels: a mechanism of neurovascular coupling. J Neurosci (2006) 3.23
Signaling at the gliovascular interface. J Neurosci (2003) 3.16
Presynaptic Ca2+-activated K+ channels in glutamatergic hippocampal terminals and their role in spike repolarization and regulation of transmitter release. J Neurosci (2001) 2.48
Functional coupling of ryanodine receptors to KCa channels in smooth muscle cells from rat cerebral arteries. J Gen Physiol (1999) 2.42
Calcium dynamics in cortical astrocytes and arterioles during neurovascular coupling. Circ Res (2004) 2.17
Intercellular calcium signaling mediated by point-source burst release of ATP. Proc Natl Acad Sci U S A (2002) 2.08
Micromolar Ca(2+) from sparks activates Ca(2+)-sensitive K(+) channels in rat cerebral artery smooth muscle. Am J Physiol Cell Physiol (2001) 2.04
Intravascular pressure regulates local and global Ca(2+) signaling in cerebral artery smooth muscle cells. Am J Physiol Cell Physiol (2001) 1.85
Haem can bind to and inhibit mammalian calcium-dependent Slo1 BK channels. Nature (2003) 1.84
Role of astrocytes in cerebrovascular regulation. J Appl Physiol (1985) (2006) 1.82
Does the release of potassium from astrocyte endfeet regulate cerebral blood flow? Science (1987) 1.81
Heme is a carbon monoxide receptor for large-conductance Ca2+-activated K+ channels. Circ Res (2005) 1.80
Vesicular transmitter release from astrocytes. Glia (2006) 1.71
NMDA receptors mediate neuron-to-glia signaling in mouse cortical astrocytes. J Neurosci (2006) 1.69
Functional hyperemia in the brain: hypothesis for astrocyte-derived vasodilator metabolites. Stroke (1998) 1.58
Heme oxygenase-2 is activated by calcium-calmodulin. J Biol Chem (2004) 1.41
Carbon monoxide dilates cerebral arterioles by enhancing the coupling of Ca2+ sparks to Ca2+-activated K+ channels. Circ Res (2002) 1.38
Carbon monoxide activates KCa channels in newborn arteriole smooth muscle cells by increasing apparent Ca2+ sensitivity of alpha-subunits. Am J Physiol Heart Circ Physiol (2003) 1.32
Contributions of astrocytes and CO to pial arteriolar dilation to glutamate in newborn pigs. Am J Physiol Heart Circ Physiol (2006) 1.19
Sarcoplasmic reticulum calcium load regulates rat arterial smooth muscle calcium sparks and transient K(Ca) currents. J Physiol (2002) 1.16
Carbon monoxide from heme oxygenase-2 Is a tonic regulator against NO-dependent vasodilatation in the adult rat cerebral microcirculation. Circ Res (2005) 1.16
Dynamic inositol trisphosphate-mediated calcium signals within astrocytic endfeet underlie vasodilation of cerebral arterioles. J Gen Physiol (2006) 1.16
Carbon monoxide and cerebral microvascular tone in newborn pigs. Am J Physiol (1999) 1.15
Dual regulation of the cerebral microvasculature by epoxyeicosatrienoic acids. Trends Cardiovasc Med (2001) 1.12
Neurovascular coupling is not mediated by potassium siphoning from glial cells. J Neurosci (2007) 1.12
Gene expression profiles of heme oxygenase isoforms in the rat brain. Brain Res (2002) 1.09
Different mechanisms underlying the stimulation of K(Ca) channels by nitric oxide and carbon monoxide. J Clin Invest (2002) 1.06
Ca2+ sparks and their function in human cerebral arteries. Stroke (2002) 1.06
Nitric oxide increases carbon monoxide production by piglet cerebral microvessels. Am J Physiol Heart Circ Physiol (2005) 1.05
Effects of carbon monoxide and heme oxygenase inhibitors in cerebral vessels of rats and mice. Am J Physiol Heart Circ Physiol (2006) 1.00
The permissive role of endothelial NO in CO-induced cerebrovascular dilation. Am J Physiol Heart Circ Physiol (2004) 0.99
Carbon monoxide produced by isolated arterioles attenuates pressure-induced vasoconstriction. Am J Physiol Heart Circ Physiol (2001) 0.99
Influence of the glia limitans on pial arteriolar relaxation in the rat. Am J Physiol Heart Circ Physiol (2004) 0.98
Role of carbon monoxide in glutamate receptor-induced dilation of newborn pig pial arterioles. Am J Physiol Heart Circ Physiol (2002) 0.98
P-450 epoxygenase and NO synthase inhibitors reduce cerebral blood flow response to N-methyl-D-aspartate. Am J Physiol Heart Circ Physiol (2000) 0.98
Age and species dependence of pial arteriolar responses to topical carbon monoxide in vivo. Exp Biol Med (Maywood) (2007) 0.98
Regulation of CO production in cerebral microvessels of newborn pigs. Am J Physiol Heart Circ Physiol (2003) 0.97
Calcium release from intracellular stores in rodent astrocytes and neurons in situ. Cell Calcium (2004) 0.97
Effect of carbon monoxide on rabbit cerebral arteries. Stroke (1994) 0.93
Heme oxygenase-mediated vasodilation involves vascular smooth muscle cell hyperpolarization. Am J Physiol Heart Circ Physiol (2003) 0.93
Mechanism of glutamate stimulation of CO production in cerebral microvessels. Am J Physiol Heart Circ Physiol (2003) 0.93
The role of the glia limitans in ADP-induced pial arteriolar relaxation in intact and ovariectomized female rats. Am J Physiol Heart Circ Physiol (2004) 0.92
Carbon monoxide contributes to hypotension-induced cerebrovascular vasodilation in piglets. Am J Physiol Heart Circ Physiol (2006) 0.91
Ionic mechanisms mediating the myogenic response in newborn porcine cerebral arteries. Am J Physiol Heart Circ Physiol (2004) 0.88
The vasorelaxation of cerebral arteries by carbon monoxide. Exp Biol Med (Maywood) (2001) 0.88
Contribution of the heme oxygenase pathway to the maintenance of the hypothalamic blood flow during diminished nitric oxide synthesis. J Cereb Blood Flow Metab (2003) 0.86
KCa channel insensitivity to Ca2+ sparks underlies fractional uncoupling in newborn cerebral artery smooth muscle cells. Am J Physiol Heart Circ Physiol (2006) 0.81
Carbon monoxide and dilation of blood vessels. Science (1993) 0.80
In vivo role of heme oxygenase in ischemic coronary vasodilation. Am J Physiol Heart Circ Physiol (2004) 0.78
Mitochondria-derived reactive oxygen species dilate cerebral arteries by activating Ca2+ sparks. Circ Res (2005) 2.29
Androgen-mediated induction of the kidney arachidonate hydroxylases is associated with the development of hypertension. Am J Physiol Regul Integr Comp Physiol (2003) 1.81
Heme is a carbon monoxide receptor for large-conductance Ca2+-activated K+ channels. Circ Res (2005) 1.80
Expression of human heme oxygenase-1 in the thick ascending limb attenuates angiotensin II-mediated increase in oxidative injury. Kidney Int (2004) 1.78
A newly discovered mycobacterial pathogen isolated from laboratory colonies of Xenopus species with lethal infections produces a novel form of mycolactone, the Mycobacterium ulcerans macrolide toxin. Infect Immun (2005) 1.73
Type 1 IP3 receptors activate BKCa channels via local molecular coupling in arterial smooth muscle cells. J Gen Physiol (2010) 1.71
TNF-alpha dilates cerebral arteries via NAD(P)H oxidase-dependent Ca2+ spark activation. Am J Physiol Cell Physiol (2005) 1.70
Nox4 NADPH oxidase mediates oxidative stress and apoptosis caused by TNF-alpha in cerebral vascular endothelial cells. Am J Physiol Cell Physiol (2008) 1.53
Epoxyeicosatrienoic acid agonist rescues the metabolic syndrome phenotype of HO-2-null mice. J Pharmacol Exp Ther (2009) 1.51
Carbon monoxide and hydrogen sulfide: gaseous messengers in cerebrovascular circulation. J Appl Physiol (1985) (2006) 1.49
Increase in heme oxygenase-1 levels ameliorates renovascular hypertension. Kidney Int (2005) 1.48
Glutamate induces oxidative stress and apoptosis in cerebral vascular endothelial cells: contributions of HO-1 and HO-2 to cytoprotection. Am J Physiol Cell Physiol (2005) 1.38
Lanthanum chloride impairs spatial learning and memory and downregulates NF-κB signalling pathway in rats. Arch Toxicol (2013) 1.38
Carbon monoxide dilates cerebral arterioles by enhancing the coupling of Ca2+ sparks to Ca2+-activated K+ channels. Circ Res (2002) 1.38
IP3 constricts cerebral arteries via IP3 receptor-mediated TRPC3 channel activation and independently of sarcoplasmic reticulum Ca2+ release. Circ Res (2008) 1.34
Carbon monoxide activates KCa channels in newborn arteriole smooth muscle cells by increasing apparent Ca2+ sensitivity of alpha-subunits. Am J Physiol Heart Circ Physiol (2003) 1.32
TMEM16A channels generate Ca²⁺-activated Cl⁻ currents in cerebral artery smooth muscle cells. Am J Physiol Heart Circ Physiol (2011) 1.29
Essential role for smooth muscle BK channels in alcohol-induced cerebrovascular constriction. Proc Natl Acad Sci U S A (2004) 1.29
HO-2 provides endogenous protection against oxidative stress and apoptosis caused by TNF-alpha in cerebral vascular endothelial cells. Am J Physiol Cell Physiol (2006) 1.25
Mitochondrial modulation of Ca2+ sparks and transient KCa currents in smooth muscle cells of rat cerebral arteries. J Physiol (2004) 1.25
Parathyroid hormone activates TRPV5 via PKA-dependent phosphorylation. J Am Soc Nephrol (2009) 1.24
Carbon monoxide as an endogenous vascular modulator. Am J Physiol Heart Circ Physiol (2011) 1.23
TMEM16A/ANO1 channels contribute to the myogenic response in cerebral arteries. Circ Res (2012) 1.23
Up-regulation of heme oxygenase provides vascular protection in an animal model of diabetes through its antioxidant and antiapoptotic effects. J Pharmacol Exp Ther (2006) 1.22
Smooth muscle cell alpha2delta-1 subunits are essential for vasoregulation by CaV1.2 channels. Circ Res (2009) 1.21
Photolysis of intracellular caged sphingosine-1-phosphate causes Ca2+ mobilization independently of G-protein-coupled receptors. FEBS Lett (2003) 1.21
Type 1 inositol 1,4,5-trisphosphate receptors mediate UTP-induced cation currents, Ca2+ signals, and vasoconstriction in cerebral arteries. Am J Physiol Cell Physiol (2008) 1.20
Isoform-selective physical coupling of TRPC3 channels to IP3 receptors in smooth muscle cells regulates arterial contractility. Circ Res (2010) 1.19
A novel Ca(V)1.2 N terminus expressed in smooth muscle cells of resistance size arteries modifies channel regulation by auxiliary subunits. J Biol Chem (2007) 1.17
Heme oxygenase-2 is a critical determinant for execution of an acute inflammatory and reparative response. Am J Pathol (2006) 1.17
Sarcoplasmic reticulum calcium load regulates rat arterial smooth muscle calcium sparks and transient K(Ca) currents. J Physiol (2002) 1.16
Heme oxygenase gene targeting to adipocytes attenuates adiposity and vascular dysfunction in mice fed a high-fat diet. Hypertension (2012) 1.14
Assessment of cerebrovascular autoregulation: changes of highest modal frequency of cerebrovascular pressure transmission with cerebral perfusion pressure. Stroke (2004) 1.13
Heme oxygenase-2 deficiency contributes to diabetes-mediated increase in superoxide anion and renal dysfunction. J Am Soc Nephrol (2006) 1.13
Sulfonylurea receptor-dependent and -independent pathways mediate vasodilation induced by ATP-sensitive K+ channel openers. Mol Pharmacol (2008) 1.13
Cytochrome P450-dependent eicosapentaenoic acid metabolites are novel BK channel activators. Hypertension (2002) 1.11
Hydrogen sulfide and cerebral microvascular tone in newborn pigs. Am J Physiol Heart Circ Physiol (2010) 1.10
Androgen-dependent hypertension is mediated by 20-hydroxy-5,8,11,14-eicosatetraenoic acid-induced vascular dysfunction: role of inhibitor of kappaB Kinase. Hypertension (2011) 1.10
Renal vascular cytochrome P450-derived eicosanoids in androgen-induced hypertension. Pharmacol Rep (2008) 1.10
Vasoconstriction resulting from dynamic membrane trafficking of TRPM4 in vascular smooth muscle cells. Am J Physiol Cell Physiol (2010) 1.09
Alternative splicing of Cav1.2 channel exons in smooth muscle cells of resistance-size arteries generates currents with unique electrophysiological properties. Am J Physiol Heart Circ Physiol (2009) 1.08
Cerebroprotective functions of HO-2. Curr Pharm Des (2008) 1.07
Profile of lipid and protein autacoids in diabetic vitreous correlates with the progression of diabetic retinopathy. Diabetes (2010) 1.05
CYP4A2-induced hypertension is 20-hydroxyeicosatetraenoic acid- and angiotensin II-dependent. Hypertension (2010) 1.05
Epidermal growth factor receptor signaling in the kidney: key roles in physiology and disease. Hypertension (2008) 1.05
Crosstalk between EET and HO-1 downregulates Bach1 and adipogenic marker expression in mesenchymal stem cell derived adipocytes. Prostaglandins Other Lipid Mediat (2011) 1.04
Increased heme-oxygenase 1 expression in mesenchymal stem cell-derived adipocytes decreases differentiation and lipid accumulation via upregulation of the canonical Wnt signaling cascade. Stem Cell Res Ther (2013) 1.04
11,12-epoxyeicosatrienoic acid stimulates heme-oxygenase-1 in endothelial cells. Prostaglandins Other Lipid Mediat (2006) 1.03
Role of cGMP in carbon monoxide-induced cerebral vasodilation in piglets. Am J Physiol Heart Circ Physiol (2004) 1.03
Heme oxygenase-1 induction attenuates corneal inflammation and accelerates wound healing after epithelial injury. Invest Ophthalmol Vis Sci (2008) 1.03
Genetic ablation of caveolin-1 modifies Ca2+ spark coupling in murine arterial smooth muscle cells. Am J Physiol Heart Circ Physiol (2006) 1.02
Nox4 NADPH oxidase-derived reactive oxygen species, via endogenous carbon monoxide, promote survival of brain endothelial cells during TNF-α-induced apoptosis. Am J Physiol Cell Physiol (2010) 1.02
20-HETE and blood pressure regulation: clinical implications. Cardiol Rev (2013) 1.02
Epoxyeicosatrienoic acid agonist regulates human mesenchymal stem cell-derived adipocytes through activation of HO-1-pAKT signaling and a decrease in PPARγ. Stem Cells Dev (2010) 1.01
Hydrogen sulfide activates Ca²⁺ sparks to induce cerebral arteriole dilatation. J Physiol (2012) 1.00
Caveolin-1 assembles type 1 inositol 1,4,5-trisphosphate receptors and canonical transient receptor potential 3 channels into a functional signaling complex in arterial smooth muscle cells. J Biol Chem (2010) 0.99
EET agonist prevents adiposity and vascular dysfunction in rats fed a high fat diet via a decrease in Bach 1 and an increase in HO-1 levels. Prostaglandins Other Lipid Mediat (2011) 0.99
The permissive role of endothelial NO in CO-induced cerebrovascular dilation. Am J Physiol Heart Circ Physiol (2004) 0.99
Role of the alpha-kinase domain in transient receptor potential melastatin 6 channel and regulation by intracellular ATP. J Biol Chem (2008) 0.99
Cerebroprotective effects of the CO-releasing molecule CORM-A1 against seizure-induced neonatal vascular injury. Am J Physiol Heart Circ Physiol (2007) 0.99
Role of carbon monoxide in glutamate receptor-induced dilation of newborn pig pial arterioles. Am J Physiol Heart Circ Physiol (2002) 0.98
Role of IFN-alpha/beta signaling in the prevention of genital herpes virus type 2 infection. J Reprod Immunol (2006) 0.98
Age and species dependence of pial arteriolar responses to topical carbon monoxide in vivo. Exp Biol Med (Maywood) (2007) 0.98
Dynamic regulation of β1 subunit trafficking controls vascular contractility. Proc Natl Acad Sci U S A (2014) 0.98
Endogenous heme oxygenase prevents impairment of cerebral vascular functions caused by seizures. Am J Physiol Heart Circ Physiol (2003) 0.98
Smooth muscle cell transient receptor potential polycystin-2 (TRPP2) channels contribute to the myogenic response in cerebral arteries. J Physiol (2013) 0.97
Mode changes of cerebrovascular pressure transmission induced by cerebral vasodilation. J Neurotrauma (2007) 0.97
Regulation of cyclooxygenase by the heme-heme oxygenase system in microvessel endothelial cells. J Pharmacol Exp Ther (2002) 0.97
Hydrogen sulfide dilates cerebral arterioles by activating smooth muscle cell plasma membrane KATP channels. Am J Physiol Heart Circ Physiol (2011) 0.96
Permissive contributions of NO and prostacyclin in CO-induced cerebrovascular dilation in piglets. Am J Physiol Heart Circ Physiol (2005) 0.96
Ionotropic glutamate receptors in cerebral microvascular endothelium are functionally linked to heme oxygenase. J Cereb Blood Flow Metab (2003) 0.95
Ca(V)1.2 channel N-terminal splice variants modulate functional surface expression in resistance size artery smooth muscle cells. J Biol Chem (2011) 0.95
Carbon monoxide mediates vasodilator effects of glutamate in isolated pressurized cerebral arterioles of newborn pigs. Am J Physiol Heart Circ Physiol (2003) 0.94
Androgen-sensitive hypertension associates with upregulated vascular CYP4A12-20-HETE synthase. J Am Soc Nephrol (2013) 0.94
Mitochondria control functional CaV1.2 expression in smooth muscle cells of cerebral arteries. Circ Res (2010) 0.94
Caveolin-1 abolishment attenuates the myogenic response in murine cerebral arteries. Am J Physiol Heart Circ Physiol (2006) 0.94
Subtype identification and functional characterization of ryanodine receptors in rat cerebral artery myocytes. Am J Physiol Cell Physiol (2010) 0.93
High potassium intake enhances the inhibitory effect of 11,12-EET on ENaC. J Am Soc Nephrol (2010) 0.93
An elevation in physical coupling of type 1 inositol 1,4,5-trisphosphate (IP3) receptors to transient receptor potential 3 (TRPC3) channels constricts mesenteric arteries in genetic hypertension. Hypertension (2012) 0.93
Epileptic seizures cause extended postictal cerebral vascular dysfunction that is prevented by HO-1 overexpression. Am J Physiol Heart Circ Physiol (2005) 0.92
Epileptic seizures increase circulating endothelial cells in peripheral blood as early indicators of cerebral vascular damage. Am J Physiol Heart Circ Physiol (2010) 0.92
Carbon monoxide contributes to hypotension-induced cerebrovascular vasodilation in piglets. Am J Physiol Heart Circ Physiol (2006) 0.91
CaV1.3 channels and intracellular calcium mediate osmotic stress-induced N-terminal c-Jun kinase activation and disruption of tight junctions in Caco-2 CELL MONOLAYERS. J Biol Chem (2011) 0.91
Proteome of monocytes primed with lipopolysaccharide: analysis of the abundant proteins. Proteomics (2003) 0.91
Cl⁻ channels in smooth muscle cells. Pflugers Arch (2014) 0.91
Carbon monoxide and Ca2+-activated K+ channels in cerebral arteriolar responses to glutamate and hypoxia in newborn pigs. Am J Physiol Heart Circ Physiol (2007) 0.90
Cerebrovascular dilation via selective targeting of the cholane steroid-recognition site in the BK channel β1-subunit by a novel nonsteroidal agent. Mol Pharmacol (2013) 0.90
Transcriptional upregulation of α2δ-1 elevates arterial smooth muscle cell voltage-dependent Ca2+ channel surface expression and cerebrovascular constriction in genetic hypertension. Hypertension (2012) 0.90
L-type voltage-dependent Ca2+ channels in cerebral microvascular endothelial cells and ET-1 biosynthesis. Am J Physiol Cell Physiol (2002) 0.90