Published in Mol Immunol on November 09, 2007
Paths reunited: Initiation of the classical and lectin pathways of complement activation. Immunobiology (2009) 1.50
Structure of the haptoglobin-haemoglobin complex. Nature (2012) 1.40
Structural basis of the C1q/C1s interaction and its central role in assembly of the C1 complex of complement activation. Proc Natl Acad Sci U S A (2013) 1.12
Analogous interactions in initiating complexes of the classical and lectin pathways of complement. J Immunol (2009) 1.06
Mapping surface accessibility of the C1r/C1s tetramer by chemical modification and mass spectrometry provides new insights into assembly of the human C1 complex. J Biol Chem (2010) 0.94
Quantitative characterization of the activation steps of mannan-binding lectin (MBL)-associated serine proteases (MASPs) points to the central role of MASP-1 in the initiation of the complement lectin pathway. J Biol Chem (2013) 0.91
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Structure and activation of C1, the complex initiating the classical pathway of the complement cascade. Proc Natl Acad Sci U S A (2017) 0.89
Initiating protease with modular domains interacts with β-glucan recognition protein to trigger innate immune response in insects. Proc Natl Acad Sci U S A (2015) 0.79
Purification, crystallization and preliminary X-ray analysis of human mannose-binding lectin-associated serine protease-1 (MASP-1) catalytic region. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.79
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Imprinting along the Kcnq1 domain on mouse chromosome 7 involves repressive histone methylation and recruitment of Polycomb group complexes. Nat Genet (2004) 3.33
Mapping the core of the beta(2)-microglobulin amyloid fibril by H/D exchange. Nat Struct Biol (2002) 2.99
The organization of histone H3 modifications as revealed by a panel of specific monoclonal antibodies. Cell Struct Funct (2008) 2.75
Allele-specific histone lysine methylation marks regulatory regions at imprinted mouse genes. EMBO J (2002) 2.40
A toxic monomeric conformer of the polyglutamine protein. Nat Struct Mol Biol (2007) 2.33
Site-specific analysis of histone methylation and acetylation. Methods Mol Biol (2004) 1.97
Direct observation of Abeta amyloid fibril growth and inhibition. J Mol Biol (2004) 1.82
Protein folding by the effects of macromolecular crowding. Protein Sci (2004) 1.71
3D structure of amyloid protofilaments of beta2-microglobulin fragment probed by solid-state NMR. Proc Natl Acad Sci U S A (2006) 1.70
One Argonaute family member, Eif2c2 (Ago2), is essential for development and appears not to be involved in DNA methylation. Genomics (2007) 1.56
Direct observation of amyloid fibril growth monitored by thioflavin T fluorescence. J Biol Chem (2003) 1.52
Natural substrates and inhibitors of mannan-binding lectin-associated serine protease-1 and -2: a study on recombinant catalytic fragments. J Immunol (2003) 1.43
Simultaneous activation of complement and coagulation by MBL-associated serine protease 2. PLoS One (2007) 1.42
AlphaB-crystallin, a small heat-shock protein, prevents the amyloid fibril growth of an amyloid beta-peptide and beta2-microglobulin. Biochem J (2005) 1.41
Low concentrations of sodium dodecyl sulfate induce the extension of beta 2-microglobulin-related amyloid fibrils at a neutral pH. Biochemistry (2004) 1.39
Core and heterogeneity of beta2-microglobulin amyloid fibrils as revealed by H/D exchange. J Mol Biol (2004) 1.35
Critical balance of electrostatic and hydrophobic interactions is required for beta 2-microglobulin amyloid fibril growth and stability. Biochemistry (2005) 1.34
Amyloid fibril formation in the context of full-length protein: effects of proline mutations on the amyloid fibril formation of beta2-microglobulin. J Biol Chem (2003) 1.31
Glycosaminoglycans enhance the trifluoroethanol-induced extension of beta 2-microglobulin-related amyloid fibrils at a neutral pH. J Am Soc Nephrol (2004) 1.29
Ultrasonication-induced amyloid fibril formation of beta2-microglobulin. J Biol Chem (2005) 1.27
Investigation of a peptide responsible for amyloid fibril formation of beta 2-microglobulin by achromobacter protease I. J Biol Chem (2001) 1.27
MASP-1, a promiscuous complement protease: structure of its catalytic region reveals the basis of its broad specificity. J Immunol (2009) 1.25
Nuclear magnetic resonance characterization of the refolding intermediate of beta2-microglobulin trapped by non-native prolyl peptide bond. J Mol Biol (2005) 1.25
A true autoactivating enzyme. Structural insight into mannose-binding lectin-associated serine protease-2 activations. J Biol Chem (2005) 1.23
Branching in amyloid fibril growth. Biophys J (2009) 1.21
Distinguishing crystal-like amyloid fibrils and glass-like amorphous aggregates from their kinetics of formation. Proc Natl Acad Sci U S A (2012) 1.19
Revised mechanism of complement lectin-pathway activation revealing the role of serine protease MASP-1 as the exclusive activator of MASP-2. Proc Natl Acad Sci U S A (2012) 1.17
The structure of MBL-associated serine protease-2 reveals that identical substrate specificities of C1s and MASP-2 are realized through different sets of enzyme-substrate interactions. J Mol Biol (2004) 1.16
Seeding-dependent propagation and maturation of amyloid fibril conformation. J Mol Biol (2005) 1.15
Differential substrate and inhibitor profiles for human MASP-1 and MASP-2. Mol Immunol (2004) 1.15
RAS/RAF/MEK/ERK and PI3K/PTEN/AKT Signaling in Malignant Melanoma Progression and Therapy. Dermatol Res Pract (2011) 1.15
Crystal structure reveals basis for the inhibitor resistance of human brain trypsin. J Mol Biol (2002) 1.14
Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor. Biochem Biophys Res Commun (2008) 1.14
Complement protease MASP-1 activates human endothelial cells: PAR4 activation is a link between complement and endothelial function. J Immunol (2009) 1.13
Structural basis of the C1q/C1s interaction and its central role in assembly of the C1 complex of complement activation. Proc Natl Acad Sci U S A (2013) 1.12
Lipocalin-type prostaglandin D synthase/beta-trace is a major amyloid beta-chaperone in human cerebrospinal fluid. Proc Natl Acad Sci U S A (2007) 1.11
The action of MBL-associated serine protease 1 (MASP1) on factor XIII and fibrinogen. Biochim Biophys Acta (2008) 1.10
Principal component analysis of the pH-dependent conformational transitions of bovine beta-lactoglobulin monitored by heteronuclear NMR. Proc Natl Acad Sci U S A (2007) 1.09
Human fetuin/alpha2HS-glycoprotein level as a novel indicator of liver cell function and short-term mortality in patients with liver cirrhosis and liver cancer. Eur J Gastroenterol Hepatol (2002) 1.08
Structural defects and the diagnosis of amyloidogenic propensity. Proc Natl Acad Sci U S A (2003) 1.08
Structural basis for activation of the complement system by component C4 cleavage. Proc Natl Acad Sci U S A (2012) 1.08
C1 inhibitor serpin domain structure reveals the likely mechanism of heparin potentiation and conformational disease. J Biol Chem (2007) 1.08
A comprehensive model for packing and hydration for amyloid fibrils of beta2-microglobulin. J Biol Chem (2008) 1.07
Development of a technique for the investigation of folding dynamics of single proteins for extended time periods. Proc Natl Acad Sci U S A (2007) 1.07
Ultrasonication-dependent production and breakdown lead to minimum-sized amyloid fibrils. Proc Natl Acad Sci U S A (2009) 1.06
Mechanism by which the amyloid-like fibrils of a beta 2-microglobulin fragment are induced by fluorine-substituted alcohols. J Mol Biol (2006) 1.06
Dissolution of beta2-microglobulin amyloid fibrils by dimethylsulfoxide. J Biochem (2003) 1.06
Active site closure facilitates juxtaposition of reactant atoms for initiation of catalysis by human dUTPase. FEBS Lett (2007) 1.05
Increase in the conformational flexibility of beta 2-microglobulin upon copper binding: a possible role for copper in dialysis-related amyloidosis. Protein Sci (2004) 1.04
Structure, folding dynamics, and amyloidogenesis of D76N β2-microglobulin: roles of shear flow, hydrophobic surfaces, and α-crystallin. J Biol Chem (2013) 1.04
The role of disulfide bond in the amyloidogenic state of beta(2)-microglobulin studied by heteronuclear NMR. Protein Sci (2002) 1.04
Clustering of disease-causing mutations on the domain-domain interfaces of ABCC6. Biochem Biophys Res Commun (2009) 1.03
Real-time and single fibril observation of the formation of amyloid beta spherulitic structures. J Biol Chem (2006) 1.03
Biological variations of MASP-3 and MAp44, two splice products of the MASP1 gene involved in regulation of the complement system. J Immunol Methods (2010) 1.03
Visualization and classification of amyloid beta supramolecular assemblies. Biochemistry (2007) 1.02
Flexible segments modulate co-folding of dUTPase and nucleocapsid proteins. Nucleic Acids Res (2006) 1.02
Molecular Network Associated with MITF in Skin Melanoma Development and Progression. J Skin Cancer (2011) 1.01
Direct measurement of the thermodynamic parameters of amyloid formation by isothermal titration calorimetry. J Biol Chem (2004) 1.01
Role of phosphate chain mobility of MgATP in completing the 3-phosphoglycerate kinase catalytic site: binding, kinetic, and crystallographic studies with ATP and MgATP. Biochemistry (2004) 1.00
Unconventional translation initiation of human trypsinogen 4 at a CUG codon with an N-terminal leucine. A possible means to regulate gene expression. FEBS J (2007) 0.99
Early complement proteases: C1r, C1s and MASPs. A structural insight into activation and functions. Mol Immunol (2009) 0.99
Seeding-dependent maturation of beta2-microglobulin amyloid fibrils at neutral pH. J Biol Chem (2005) 0.98
Hierarchic finite level energy landscape model: to describe the refolding kinetics of phosphoglycerate kinase. J Biol Chem (2006) 0.98
Directed evolution reveals the binding motif preference of the LC8/DYNLL hub protein and predicts large numbers of novel binders in the human proteome. PLoS One (2011) 0.98
Protein folding: could hydrophobic collapse be coupled with hydrogen-bond formation? FEBS Lett (2003) 0.98
Amyloid nucleation triggered by agitation of beta2-microglobulin under acidic and neutral pH conditions. Biochemistry (2008) 0.98
Conformation of amyloid fibrils of beta2-microglobulin probed by tryptophan mutagenesis. J Biol Chem (2006) 0.97
Direct observation of amyloid fibril growth, propagation, and adaptation. Acc Chem Res (2006) 0.97
Hexafluoroisopropanol induces amyloid fibrils of islet amyloid polypeptide by enhancing both hydrophobic and electrostatic interactions. J Biol Chem (2011) 0.96
Manipulating monomer-dimer equilibrium of bovine Beta -lactoglobulin by amino acid substitution. J Biol Chem (2002) 0.96
Asymmetric effect of domain interactions on the kinetics of folding in yeast phosphoglycerate kinase. Protein Sci (2005) 0.95
Direct observation of amyloid growth monitored by total internal reflection fluorescence microscopy. Methods Enzymol (2006) 0.95
Altered active site flexibility and a structural metal-binding site in eukaryotic dUTPase: kinetic characterization, folding, and crystallographic studies of the homotrimeric Drosophila enzyme. J Biol Chem (2004) 0.95
C1, MBL-MASPs and C1-inhibitor: novel approaches for targeting complement-mediated inflammation. Trends Mol Med (2008) 0.95
Sunlight exposure-mediated DNA damage in young adults. Cancer Epidemiol Biomarkers Prev (2011) 0.95
Aromatic stacking between nucleobase and enzyme promotes phosphate ester hydrolysis in dUTPase. Nucleic Acids Res (2010) 0.95
Time-resolved small-angle X-ray scattering study of the folding dynamics of barnase. J Mol Biol (2010) 0.95
Metal ion-dependent effects of clioquinol on the fibril growth of an amyloid {beta} peptide. J Biol Chem (2005) 0.94
Localization of the flagellum-specific secretion signal in Salmonella flagellin. Biochem Biophys Res Commun (2006) 0.94
Conformational stability of amyloid fibrils of beta2-microglobulin probed by guanidine-hydrochloride-induced unfolding. FEBS Lett (2004) 0.94