Published in Regul Pept on September 19, 2007
Interleukin-1beta promotes gastric atrophy through suppression of Sonic Hedgehog. Gastroenterology (2009) 1.58
Loss of parietal cell expression of Sonic hedgehog induces hypergastrinemia and hyperproliferation of surface mucous cells. Gastroenterology (2009) 1.55
Gastric Sonic Hedgehog acts as a macrophage chemoattractant during the immune response to Helicobacter pylori. Gastroenterology (2012) 1.26
Intracellular calcium release and protein kinase C activation stimulate sonic hedgehog gene expression during gastric acid secretion. Gastroenterology (2010) 1.24
Hedgehog signaling and gastrointestinal cancer. Biochim Biophys Acta (2010) 1.07
Sonic hedgehog is associated with H+-K+-ATPase-containing membranes in gastric parietal cells and secreted with histamine stimulation. Am J Physiol Gastrointest Liver Physiol (2008) 1.05
The role of sonic hedgehog reemergence during gastric cancer. Dig Dis Sci (2010) 0.90
Helicobacter pylori-induced Sonic Hedgehog expression is regulated by NFκB pathway activation: the use of a novel in vitro model to study epithelial response to infection. Helicobacter (2014) 0.87
Sonic hedgehog in gastric physiology and neoplastic transformation: friend or foe? Curr Opin Endocrinol Diabetes Obes (2009) 0.85
The role of Sonic Hedgehog as a regulator of gastric function and differentiation. Vitam Horm (2012) 0.77
Regulatory Mechanisms of the Ihh/PTHrP Signaling Pathway in Fibrochondrocytes in Entheses of Pig Achilles Tendon. Stem Cells Int (2016) 0.75
Tumor-infiltrating CD8+ lymphocytes predict clinical outcome in breast cancer. J Clin Oncol (2011) 6.13
Biologic and clinical characteristics of breast cancer with single hormone receptor positive phenotype. J Clin Oncol (2007) 3.55
Triple-negative breast cancer: distinguishing between basal and nonbasal subtypes. Clin Cancer Res (2009) 2.91
Evolutionary conservation of a coding function for D4Z4, the tandem DNA repeat mutated in facioscapulohumeral muscular dystrophy. Am J Hum Genet (2007) 2.06
High frequency of coexistence of columnar cell lesions, lobular neoplasia, and low grade ductal carcinoma in situ with invasive tubular carcinoma and invasive lobular carcinoma. Am J Surg Pathol (2007) 2.00
The biological, clinical and prognostic implications of p53 transcriptional pathways in breast cancers. J Pathol (2010) 1.79
Invasive lobular carcinoma of the breast: response to hormonal therapy and outcomes. Eur J Cancer (2007) 1.46
Morphologic and molecular evolutionary pathways of low nuclear grade invasive breast cancers and their putative precursor lesions: further evidence to support the concept of low nuclear grade breast neoplasia family. Am J Surg Pathol (2008) 1.41
Differential expression of SOX4 and SOX11 in medulloblastoma. J Neurooncol (2002) 1.36
The developmental dismantling of pluripotency is reversed by ectopic Oct4 expression. Development (2012) 1.33
An evaluation of the clinical significance of FOXP3+ infiltrating cells in human breast cancer. Breast Cancer Res Treat (2010) 1.31
CIC, a member of a novel subfamily of the HMG-box superfamily, is transiently expressed in developing granule neurons. Brain Res Mol Brain Res (2002) 1.29
The prognostic significance of PELP1 expression in invasive breast cancer with emphasis on the ER-positive luminal-like subtype. Breast Cancer Res Treat (2009) 1.27
Forkhead-box A1 (FOXA1) expression in breast cancer and its prognostic significance. Eur J Cancer (2008) 1.24
Stem cell marker expression in the Bergmann glia population of the adult mouse brain. Brain Res (2006) 1.23
MIB1/Ki-67 labelling index can classify grade 2 breast cancer into two clinically distinct subgroups. Breast Cancer Res Treat (2010) 1.12
Transferrin receptor (CD71) is a marker of poor prognosis in breast cancer and can predict response to tamoxifen. Breast Cancer Res Treat (2009) 1.08
Local allergic rhinitis: concept, pathophysiology, and management. J Allergy Clin Immunol (2012) 1.08
Loss of expression of chromosome 16q genes DPEP1 and CTCF in lobular carcinoma in situ of the breast. Breast Cancer Res Treat (2008) 1.07
CTEN (C-terminal tensin-like), a novel oncogene overexpressed in invasive breast carcinoma of poor prognosis. Breast Cancer Res Treat (2011) 1.07
Epibranchial and otic placodes are induced by a common Fgf signal, but their subsequent development is independent. Dev Biol (2006) 1.06
The prognostic significance of steroid receptor co-regulators in breast cancer: co-repressor NCOR2/SMRT is an independent indicator of poor outcome. Breast Cancer Res Treat (2007) 1.06
Gastrin - active participant or bystander in gastric carcinogenesis? Nat Rev Cancer (2006) 1.05
CIC, a gene involved in cerebellar development and ErbB signaling, is significantly expressed in medulloblastomas. J Neurooncol (2005) 1.03
Role of gastrin peptides in carcinogenesis. Cancer Lett (2007) 1.03
Selection of radiolabeled gastrin analogs for peptide receptor-targeted radionuclide therapy. J Nucl Med (2007) 1.01
FOXO3a nuclear localisation is associated with good prognosis in luminal-like breast cancer. Breast Cancer Res Treat (2011) 1.01
Gastrin enhances the angiogenic potential of endothelial cells via modulation of heparin-binding epidermal-like growth factor. Cancer Res (2006) 1.01
An antiapoptotic role for gastrin and the gastrin/CCK-2 receptor in Barrett's esophagus. Cancer Res (2004) 1.00
PIK3CA expression in invasive breast cancer: a biomarker of poor prognosis. Breast Cancer Res Treat (2009) 1.00
Comparative transcriptional profiling of the limbal epithelial crypt demonstrates its putative stem cell niche characteristics. BMC Genomics (2010) 0.99
Sox3 regulates both neural fate and differentiation in the zebrafish ectoderm. Dev Biol (2008) 0.99
Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: how vanilloids cause non-vanilloid receptor mediated cell death. Biochem Biophys Res Commun (2007) 0.98
Targeting of CCK-2 receptor-expressing tumors using a radiolabeled divalent gastrin peptide. J Nucl Med (2009) 0.98
Luminal and basal-like breast cancer cells show increased migration induced by hypoxia, mediated by an autocrine mechanism. BMC Cancer (2011) 0.97
Evolutionary trends of the first hypervariable region of the hepatitis C virus E2 protein in individuals with differing liver disease severity. J Gen Virol (2002) 0.97
Clinicopathologic and molecular significance of phospho-Akt expression in early invasive breast cancer. Breast Cancer Res Treat (2010) 0.96
SoxB1 transcription factors restrict organizer gene expression by repressing multiple events downstream of Wnt signalling. Development (2010) 0.94
Proposal for a modified grading system based on mitotic index and Bcl2 provides objective determination of clinical outcome for patients with breast cancer. J Pathol (2010) 0.94
Growth fraction as a predictor of response to chemotherapy in node-negative breast cancer. Int J Cancer (2010) 0.92
The biological and therapeutic importance of gastrin gene expression in pancreatic adenocarcinomas. Cancer Res (2004) 0.92
Effect of Z-360, a novel orally active CCK-2/gastrin receptor antagonist on tumor growth in human pancreatic adenocarcinoma cell lines in vivo and mode of action determinations in vitro. Cancer Chemother Pharmacol (2007) 0.91
RERG (Ras-like, oestrogen-regulated, growth-inhibitor) expression in breast cancer: a marker of ER-positive luminal-like subtype. Breast Cancer Res Treat (2010) 0.91
Matrix metalloproteinase expression and activity in human airway smooth muscle cells. Br J Pharmacol (2004) 0.90
Histological grading of breast cancer on needle core biopsy: the role of immunohistochemical assessment of proliferation. Histopathology (2010) 0.90
Understanding the HER family in breast cancer: interaction with ligands, dimerization and treatments. Histopathology (2010) 0.87
Norepinephrine promotes the β1-integrin-mediated adhesion of MDA-MB-231 cells to vascular endothelium by the induction of a GROα release. Mol Cancer Res (2011) 0.86
The oestrogen receptor coactivator CARM1 has an oncogenic effect and is associated with poor prognosis in breast cancer. Breast Cancer Res Treat (2013) 0.85
A change in response to Bmp signalling precedes ectodermal fate choice. Int J Dev Biol (2007) 0.85
EpCAM expression is an indicator of recurrence in basal-like breast cancer. Breast Cancer Res Treat (2011) 0.84
Elevated SP-1 transcription factor expression and activity drives basal and hypoxia-induced vascular endothelial growth factor (VEGF) expression in non-small cell lung cancer. J Biol Chem (2012) 0.84
Human epidermal growth factor receptor (HER-1:HER-3) Fc-mediated heterodimer has broad antiproliferative activity in vitro and in human tumor xenografts. Mol Cancer Ther (2008) 0.84
LEAPT: lectin-directed enzyme-activated prodrug therapy. Proc Natl Acad Sci U S A (2004) 0.84
Multicomponent synthetic polymers with viral-mimetic chemistry for nucleic acid delivery. Mol Pharm (2011) 0.84
Helicobacter pylori can induce heparin-binding epidermal growth factor expression via gastrin and its receptor. Cancer Res (2006) 0.83
The expression of ERalpha, ERbeta and PR in lobular carcinoma in situ of the breast determined using laser microdissection and real-time PCR. Histopathology (2009) 0.83
Sox group E gene expression distinguishes different types and maturational stages of glial cells in developing chick and mouse. Brain Res Dev Brain Res (2005) 0.83
Quantitative RT-PCR analysis of estrogen receptor gene expression in laser microdissected prostate cancer tissue. Prostate (2009) 0.83
Norepinephrine inhibits the migratory activity of pancreatic cancer cells. Exp Cell Res (2013) 0.82
Synthesis and preliminary anticancer activity studies of C4 and C8-modified derivatives of catechin gallate (CG) and epicatechin gallate (ECG). J Org Chem (2006) 0.81
A quantifier-based fuzzy classification system for breast cancer patients. Artif Intell Med (2013) 0.81
Analysis of the oestrogen response in an angiomyolipoma derived xenograft model. Endocr Relat Cancer (2008) 0.81
Novel strategy to study gene expression and function in developing cerebellar granule cells. J Neurosci Methods (2004) 0.81
Zebrafish rgs4 is essential for motility and axonogenesis mediated by Akt signaling. Cell Mol Life Sci (2012) 0.80
Targeting of cholecystokinin B/gastrin receptor in colonic, pancreatic and hepatocellular carcinoma cell lines. Int J Oncol (2006) 0.80
Formulation development and manufacturing of a gastrin/CCK-2 receptor targeting peptide as an intermediate drug product for a clinical imaging study. Eur J Pharm Sci (2007) 0.80
Bioluminescence imaging of human embryonic stem cells transplanted in vivo in murine and chick models. Cloning Stem Cells (2009) 0.80
Dynamic methylation and expression of Oct4 in early neural stem cells. J Anat (2010) 0.80
Heterotrimeric G protein signaling in cancer cells with regard to metastasis formation. Cell Cycle (2011) 0.79
Emerging biological therapies for pancreatic carcinoma. Eur J Surg Oncol (2002) 0.79
Variable methylation of the imprinted gene, SNRPN, supports a relationship between intracranial germ cell tumours and neural stem cells. J Neurooncol (2010) 0.79
Optimised laser microdissection of the human ocular surface epithelial regions for microarray studies. BMC Ophthalmol (2013) 0.79
Stem cell research points the way to the cell of origin for intracranial germ cell tumours. J Pathol (2012) 0.78
Immunoglobulin free light chains are biomarkers of poor prognosis in basal-like breast cancer and are potential targets in tumor-associated inflammation. Oncotarget (2014) 0.77
Akt1 mediates neuronal differentiation in zebrafish via a reciprocal interaction with notch signaling. PLoS One (2013) 0.77
Zebrafish Her8a is activated by Su(H)-dependent Notch signaling and is essential for the inhibition of neurogenesis. PLoS One (2011) 0.77
Gene transfer into intact fetal skeletal muscle grown in vitro. Muscle Nerve (2004) 0.77
Systemic in vivo delivery of siRNA to tumours using combination of polyethyleneimine and transferrin-polyethyleneimine conjugates. Biomater Sci (2015) 0.77
The surface ectoderm of the chick embryo exhibits dynamic variation in its response to neurogenic signals. Int J Dev Biol (2009) 0.77
A review of the biological and clinical characteristics of luminal-like oestrogen receptor-positive breast cancer. Histopathology (2011) 0.77
Foregut endoderm is specified early in avian development through signal(s) emanating from Hensen's node or its derivatives. Mech Dev (2008) 0.77
Reduction of TLR2 gene expression in allergic and nonallergic rhinitis. Ann Allergy Asthma Immunol (2007) 0.76
Formation of the embryonic organizer is restricted by the competitive influences of Fgf signaling and the SoxB1 transcription factors. PLoS One (2013) 0.75
Pre-gut endoderm of chick embryos is regionalized by 1.5 days of development. Dev Dyn (2002) 0.75
In-situ hybridization to sections (nonradioactive). Methods Mol Biol (2008) 0.75
Tagged polymerase chain reaction subtractive hybridization for the enrichment of phage display random peptide libraries. Anal Biochem (2005) 0.75
Idiopathic rhinitis. Curr Opin Otolaryngol Head Neck Surg (2012) 0.75
Strategies to investigate gene expression and function in granule cells. Cerebellum (2005) 0.75
Hypoxia-induced EMAP-II transcription in colorectal cancer. Egypt J Immunol (2010) 0.75
Endocytosis of anti-CCK-B/gastrin receptor antibody and effect on hepatoma cell lines. J Histochem Cytochem (2002) 0.75