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1
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Aetiology: Koch's postulates fulfilled for SARS virus.
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Nature
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2003
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7.51
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2
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Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome.
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Lancet
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2003
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6.52
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3
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Avian H5N1 influenza in cats.
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Science
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2004
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5.40
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4
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Wild ducks as long-distance vectors of highly pathogenic avian influenza virus (H5N1).
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Emerg Infect Dis
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2008
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3.37
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5
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Severity of pneumonia due to new H1N1 influenza virus in ferrets is intermediate between that due to seasonal H1N1 virus and highly pathogenic avian influenza H5N1 virus.
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J Infect Dis
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2010
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2.81
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6
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Influenza A virus (H5N1) infection in cats causes systemic disease with potential novel routes of virus spread within and between hosts.
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Am J Pathol
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2006
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2.77
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7
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Pegylated interferon-alpha protects type 1 pneumocytes against SARS coronavirus infection in macaques.
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Nat Med
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2004
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2.31
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8
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Cross-protection against lethal H5N1 challenge in ferrets with an adjuvanted pandemic influenza vaccine.
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PLoS One
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2008
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2.20
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9
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Modified vaccinia virus Ankara protects macaques against respiratory challenge with monkeypox virus.
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J Virol
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2005
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2.11
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10
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Predominant infection of CD150+ lymphocytes and dendritic cells during measles virus infection of macaques.
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PLoS Pathog
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2007
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2.09
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11
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Early target cells of measles virus after aerosol infection of non-human primates.
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PLoS Pathog
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2011
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1.80
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12
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Recombinant soluble, multimeric HA and NA exhibit distinctive types of protection against pandemic swine-origin 2009 A(H1N1) influenza virus infection in ferrets.
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J Virol
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2010
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1.55
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13
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Antiviral treatment is more effective than smallpox vaccination upon lethal monkeypox virus infection.
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Nature
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2005
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1.51
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14
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Vaccination against human influenza A/H3N2 virus prevents the induction of heterosubtypic immunity against lethal infection with avian influenza A/H5N1 virus.
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PLoS One
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2009
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1.44
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15
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Pathogenesis of Influenza A/H5N1 virus infection in ferrets differs between intranasal and intratracheal routes of inoculation.
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Am J Pathol
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2011
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1.44
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16
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Adenosine deaminase acts as a natural antagonist for dipeptidyl peptidase 4-mediated entry of the Middle East respiratory syndrome coronavirus.
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J Virol
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2013
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1.37
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17
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In vivo tropism of attenuated and pathogenic measles virus expressing green fluorescent protein in macaques.
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J Virol
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2010
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1.35
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18
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Seasonal influenza vaccine provides priming for A/H1N1 immunization.
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Sci Transl Med
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2009
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1.32
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19
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Experimental human metapneumovirus infection of cynomolgus macaques (Macaca fascicularis) results in virus replication in ciliated epithelial cells and pneumocytes with associated lesions throughout the respiratory tract.
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Am J Pathol
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2004
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1.31
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20
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Exacerbated innate host response to SARS-CoV in aged non-human primates.
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PLoS Pathog
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2010
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1.26
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21
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Recombinant modified vaccinia virus Ankara-based vaccine induces protective immunity in mice against infection with influenza virus H5N1.
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J Infect Dis
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2007
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1.18
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22
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Measles immune suppression: lessons from the macaque model.
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PLoS Pathog
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2012
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1.18
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23
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Immunization of macaques with formalin-inactivated respiratory syncytial virus (RSV) induces interleukin-13-associated hypersensitivity to subsequent RSV infection.
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J Virol
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2002
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1.17
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24
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Highly pathogenic avian influenza virus H7N7 isolated from a fatal human case causes respiratory disease in cats but does not spread systemically.
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Am J Pathol
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2010
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1.12
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25
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Multidrug resistant 2009 A/H1N1 influenza clinical isolate with a neuraminidase I223R mutation retains its virulence and transmissibility in ferrets.
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PLoS Pathog
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2011
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1.09
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26
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Immunization with West Nile virus envelope domain III protects mice against lethal infection with homologous and heterologous virus.
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Vaccine
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2007
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1.09
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27
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Comparison of temporal and spatial dynamics of seasonal H3N2, pandemic H1N1 and highly pathogenic avian influenza H5N1 virus infections in ferrets.
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PLoS One
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2012
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1.09
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28
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Prolonged influenza virus shedding and emergence of antiviral resistance in immunocompromised patients and ferrets.
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PLoS Pathog
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2013
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1.04
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29
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Characterization of humoral and cellular immune responses in cynomolgus macaques upon primary and subsequent heterologous infections with dengue viruses.
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Microbes Infect
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2007
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1.01
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30
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Pandemic H1N1 vaccine requires the use of an adjuvant to protect against challenge in naïve ferrets.
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Vaccine
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2011
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1.01
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31
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Highly pathogenic avian influenza virus (H5N1) infection in red foxes fed infected bird carcasses.
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Emerg Infect Dis
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2008
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1.00
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32
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Infection of cynomolgus macaques (Macaca fascicularis) and rhesus macaques (Macaca mulatta) with different wild-type measles viruses.
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J Gen Virol
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2007
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0.99
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33
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Experimental infection of macaques with human metapneumovirus induces transient protective immunity.
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J Gen Virol
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2007
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0.97
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34
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Efficacy of vaccination with different combinations of MF59-adjuvanted and nonadjuvanted seasonal and pandemic influenza vaccines against pandemic H1N1 (2009) influenza virus infection in ferrets.
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J Virol
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2011
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0.97
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35
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Experimental pandemic (H1N1) 2009 virus infection of cats.
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Emerg Infect Dis
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2010
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0.96
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36
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MVA-based H5N1 vaccine affords cross-clade protection in mice against influenza A/H5N1 viruses at low doses and after single immunization.
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PLoS One
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2009
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0.95
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37
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Comparison of the efficacy of early versus late viral proteins in vaccination against SIV.
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Vaccine
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2002
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0.95
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38
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Evaluation of BBG2Na in infant macaques: specific immune responses after vaccination and RSV challenge.
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Vaccine
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2004
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0.92
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39
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T-Cell tropism of simian varicella virus during primary infection.
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PLoS Pathog
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2013
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0.92
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40
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Efficacy of a live attenuated tetravalent candidate dengue vaccine in naïve and previously infected cynomolgus macaques.
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Vaccine
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2007
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0.92
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41
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Evaluation of a modified vaccinia virus Ankara (MVA)-based candidate pandemic influenza A/H1N1 vaccine in the ferret model.
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J Gen Virol
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2010
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0.91
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42
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Measles virus infection of epithelial cells in the macaque upper respiratory tract is mediated by subepithelial immune cells.
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J Virol
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2013
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0.90
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43
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Immunization of macaques with formalin-inactivated human metapneumovirus induces hypersensitivity to hMPV infection.
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Vaccine
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2007
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0.90
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44
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Fusion protein is the main determinant of metapneumovirus host tropism.
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J Gen Virol
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2009
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0.89
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45
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A recombinant influenza A virus expressing domain III of West Nile virus induces protective immune responses against influenza and West Nile virus.
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PLoS One
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2011
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0.88
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46
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Simian varicella virus infection of Chinese rhesus macaques produces ganglionic infection in the absence of rash.
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J Neurovirol
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2012
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0.85
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47
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Measles vaccination of nonhuman primates provides partial protection against infection with canine distemper virus.
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J Virol
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2014
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0.85
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48
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Evaluation of synthetic infection-enhancing lipopeptides as adjuvants for a live-attenuated canine distemper virus vaccine administered intra-nasally to ferrets.
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Vaccine
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2012
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0.85
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49
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Marked endotheliotropism of highly pathogenic avian influenza virus H5N1 following intestinal inoculation in cats.
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J Virol
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2011
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0.85
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50
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Measles vaccination of macaques by dry powder inhalation.
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Vaccine
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2006
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0.85
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51
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Aerosol measles vaccination in macaques: preclinical studies of immune responses and safety.
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Vaccine
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2006
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0.84
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52
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Distinct severe acute respiratory syndrome coronavirus-induced acute lung injury pathways in two different nonhuman primate species.
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J Virol
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2011
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0.84
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53
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Priming of measles virus-specific humoral- and cellular-immune responses in macaques by DNA vaccination.
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Vaccine
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2002
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0.83
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54
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Infection of the upper respiratory tract with seasonal influenza A(H3N2) virus induces protective immunity in ferrets against infection with A(H1N1)pdm09 virus after intranasal, but not intratracheal, inoculation.
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J Virol
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2013
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0.83
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55
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Longevity of neutralizing antibody levels in macaques vaccinated with Quil A-adjuvanted measles vaccine candidates.
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Vaccine
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2002
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0.83
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56
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Longevity of the protective immune response induced after vaccination with one or two doses of AS03A-adjuvanted split H5N1 vaccine in ferrets.
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Vaccine
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2011
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0.82
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57
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Pulmonary pathology of pandemic influenza A/H1N1 virus (2009)-infected ferrets upon longitudinal evaluation by computed tomography.
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J Gen Virol
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2011
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0.82
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58
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Immunogenicity and efficacy of two candidate human metapneumovirus vaccines in cynomolgus macaques.
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Vaccine
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2008
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0.82
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59
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Infection of lymphoid tissues in the macaque upper respiratory tract contributes to the emergence of transmissible measles virus.
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J Gen Virol
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2013
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0.81
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60
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Paramyxovirus infections in ex vivo lung slice cultures of different host species.
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J Virol Methods
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2013
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0.81
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61
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Consecutive CT in vivo lung imaging as quantitative parameter of influenza vaccine efficacy in the ferret model.
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Vaccine
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2012
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0.80
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62
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Systemic immune response after rotavirus inoculation of neonatal mice depends on source and level of purification of the virus: implications for the use of heterologous vaccine candidates.
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J Gen Virol
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2007
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0.80
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63
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Vaccination of infant macaques with a recombinant modified vaccinia virus Ankara expressing the respiratory syncytial virus F and G genes does not predispose for immunopathology.
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Vaccine
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2004
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0.80
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64
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Highly pathogenic avian influenza virus H5N1 infection in a long-distance migrant shorebird under migratory and non-migratory states.
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PLoS One
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2011
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0.79
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65
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A gastrointestinal rotavirus infection mouse model for immune modulation studies.
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Virol J
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2011
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0.79
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66
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In vitro and in vivo isolation and characterization of Duvenhage virus.
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PLoS Pathog
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2012
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0.78
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67
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Susceptibility of Carrion Crows to Experimental Infection with Lineage 1 and 2 West Nile Viruses.
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Emerg Infect Dis
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2015
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0.78
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68
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DNA vaccination of ferrets with chimeric influenza A virus hemagglutinin (H3) genes.
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Vaccine
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2002
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0.78
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69
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Reducing variation in a rabbit vaccine safety study with particular emphasis on housing conditions and handling.
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Lab Anim
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2008
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0.77
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70
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Immunogenicity and efficacy of recombinant subunit vaccines against phocid herpesvirus type 1.
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Vaccine
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2003
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0.77
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71
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Evaluation of vaccination strategies against infection with feline immunodeficiency virus (FIV) based on recombinant viral vectors expressing FIV Rev and OrfA.
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Vet Immunol Immunopathol
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2008
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0.77
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72
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Nonclinical vaccine safety evaluation: advantages of continuous temperature monitoring using abdominally implanted data loggers.
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J Appl Toxicol
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2012
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0.77
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73
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Cross-clade immunity in cats vaccinated with a canarypox-vectored avian influenza vaccine.
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Vaccine
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2010
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0.76
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74
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In vitro and in vivo replication of seal gammaherpesviruses in cells of multiple species.
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Microbes Infect
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2006
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0.76
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75
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Evaluation of ISCOM-adjuvanted subunit vaccines containing recombinant feline immunodeficiency virus Rev, OrfA and envelope protein in cats.
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Vaccine
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2008
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0.76
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76
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Activation of coagulation and tissue fibrin deposition in experimental influenza in ferrets.
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BMC Microbiol
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2014
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0.75
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77
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Experimental infection of highly pathogenic avian influenza virus H5N1 in black-headed gulls (Chroicocephalus ridibundus).
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Vet Res
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2014
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0.75
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78
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Enteric administration of a live attenuated measles vaccine does not induce protective immunity in a macaque model.
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Vaccine
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2002
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0.75
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