Possible stimulation of anti-tumor immunity using repeated cold stress: a hypothesis.

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Published in Infect Agent Cancer on November 13, 2007

Authors

Nikolai A Shevchuk1, Sasa Radoja

Author Affiliations

1: Department of Radiation Oncology, Virginia Commonwealth University, Richmond, VA, USA. nshevchuk@comcast.net

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Human physiological responses to immersion into water of different temperatures. Eur J Appl Physiol (2000) 1.18

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Mice bearing late-stage tumors have normal functional systemic T cell responses in vitro and in vivo. J Immunol (2000) 1.10

Longevity of cold-exposed rats: a reevaluation of the "rate-of-living theory". J Appl Physiol (1985) (1986) 1.09

Cold exposure: human immune responses and intracellular cytokine expression. Med Sci Sports Exerc (2002) 1.07

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Hormesis/preconditioning mechanisms, the nervous system and aging. Ageing Res Rev (2006) 1.04

Hemorrhage increases cytokine expression in lung mononuclear cells in mice: involvement of catecholamines in nuclear factor-kappaB regulation and cytokine expression. J Clin Invest (1997) 1.04

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Heat balance precedes stabilization of body temperatures during cold water immersion. J Appl Physiol (1985) (2003) 1.00

Sympathetic neural modulation of the immune system. I. Depression of T cell immunity in vivo and vitro following chemical sympathectomy. Brain Behav Immun (1989) 0.99

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The influence of cold or isolation stress on neuroinvasiveness and virulence of an attenuated variant of West Nile virus. Arch Virol (1989) 0.97

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Testosterone-induced abrogation of self-healing of Plasmodium chabaudi malaria in B10 mice: mediation by spleen cells. Infect Immun (1991) 0.93

Role of beta-endorphin, corticotropin-releasing hormone, and autonomic nervous system in mediation of the effect of chronic ethanol on natural killer cell cytolytic activity. Alcohol Clin Exp Res (2006) 0.92

Responses of sympathetic nervous system to cold exposure in vibration syndrome subjects and age-matched healthy controls. Int Arch Occup Environ Health (1990) 0.90

Stimulating effect of triiodothyronine on cell-mediated immunity. Eur J Clin Pharmacol (1980) 0.90

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Cellular and mucosal immune reactions to mental and cold stress: associations with gender and cardiovascular reactivity. Psychophysiology (2002) 0.89

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Stress-induced neuroinvasiveness of a neurovirulent noninvasive Sindbis virus in cold or isolation subjected mice. Life Sci (1991) 0.87

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Evidence for a role of endogenous corticotropin-releasing factor in cold, ether, immobilization, and traumatic stress. Proc Natl Acad Sci U S A (1985) 0.86

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Endocrine regulation of subcutaneous fat metabolism during cold exposure in humans. Ann N Y Acad Sci (2002) 0.85

Alteration of lymphocyte reactivities by thyroid hormones. Int J Immunopharmacol (1986) 0.84

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Cold swim stress-induced changes in the levels of opioid peptides in the rat CNS and peripheral tissues. Pharmacol Biochem Behav (1988) 0.83

Dehydroepiandrosterone protects mice inoculated with West Nile virus and exposed to cold stress. J Med Virol (1992) 0.83

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Immunosuppression in mice induced by cold water stress. Brain Behav Immun (1990) 0.83

Pulmonary oedema precipitated by cold water swimming. Br J Sports Med (2004) 0.82

Beta-endorphin stimulates rat T lymphocyte proliferation. J Neuroimmunol (1990) 0.82

Effects of cold stress on spleen cell proliferation and cytokine production during chronic Toxoplasma gondii infection. Neuroimmunomodulation (2004) 0.82

The effects of interleukin-6 on tumor-infiltrating lymphocytes derived from human renal cell cancer. J Urol (1991) 0.82

Thyroxine-dependent modulation of natural killer activity. J Exp Pathol (1987) 0.81

Interplay in vitro between ACTH, beta-endorphin, and glucocorticoids in the modulation of spontaneous and lymphokine-inducible human natural killer (NK) cell activity. Brain Behav Immun (1993) 0.81

Modulation of cellular immune responses by cold water swim stress in the rat. Dev Comp Immunol (1993) 0.81

ACTH enhancement of T-lymphocyte cytotoxic responses. Cell Mol Neurobiol (2005) 0.81

Effects of elevated plasma noradrenaline concentration on the immune system in humans. Eur J Appl Physiol Occup Physiol (1998) 0.81

The effect of cold stress on lymphocyte proliferation in fetal ethanol-exposed rats. Alcohol Clin Exp Res (1997) 0.80

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Interferon-gamma secretion of peripheral blood CD8+ T lymphocytes in patients with bronchial asthma: in vitro stimulus determines cytokine production. Clin Exp Immunol (2001) 0.80

Interleukin-6 is constitutively produced by human CTL clones and is required to maintain their cytolytic function. Cell Immunol (1991) 0.80

Oral testosterone in male rats and the development of experimental autoimmune encephalomyelitis. Neuroimmunomodulation (2005) 0.80

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Effect of synthetic beta-endorphin-like peptide immunorphin on human T lymphocytes. Biochemistry (Mosc) (2002) 0.80

Effects of thyroxine on T-cell counts and tumour cell rejection in mice. Acta Endocrinol (Copenh) (1976) 0.79

Regulation of the immune system by sympathetic neural mechanisms. Prog Neuropsychopharmacol Biol Psychiatry (1987) 0.79

Effect of acute cold exposure on ACTH and zinc concentrations in human plasma. Jpn J Physiol (1987) 0.79

Ultracytochemical studies of the effects of aluminum on the blood-brain barrier of mice. J Histochem Cytochem (1994) 0.79

Blood lymphocyte subsets in rats with adjuvant arthritis. Ann Rheum Dis (1994) 0.79

Cold stress-induced modulation of cell immunity during acute Toxoplasma gondii infection in mice. J Parasitol (1999) 0.79

Effects of profound hypothermia on the blood-brain barrier permeability in acute and chronically ethanol treated rats. Forensic Sci Int (2001) 0.79

Natural killer activity and thyroid hormone levels in young and elderly persons. Gerontology (2001) 0.79

Physiology and clinical relevance of induced hypothermia. Neurocrit Care (2004) 0.79

Thermoregulatory, metabolic and sympathoadrenal responses to repeated brief exposure to cold. Scand J Clin Lab Invest (1998) 0.78

Cytolysis of tumor necrosis factor (TNF)-resistant tumor targets. Differential cytotoxicity of monocytes activated by the interferons, IL-2, and TNF. J Immunol (1988) 0.78

Cold swim stress leads to enhanced splenocyte responsiveness to concanavalin A, decreased serum testosterone, and increased serum corticosterone, glucose, and protein. Life Sci (1996) 0.78

Specific and nonspecific reactions of mouse immune system under the effect of short-term exposure in warm and/or cold water. Bull Exp Biol Med (2005) 0.78

Endogenous pain inhibitory systems activated by spatial summation are opioid-mediated. Neurosci Lett (2006) 0.78

Sex-related responses of beta-endorphin, ACTH, GH and PRL to cold exposure in humans. Acta Endocrinol (Copenh) (1992) 0.77

Long-term effects of thyroid hormone on lymphocyte subsets in spleens and thymuses of mice. Endocr J (1995) 0.77

Amphetamine enhances natural killer cytotoxic activity via beta-adrenergic mechanism. J Physiol Pharmacol (2006) 0.77

Different mitogen-mediated Beta-adrenergic receptor modulation in murine T lymphocytes depending on the thyroid status. Neuroimmunomodulation (2005) 0.77

Bidirectional effects of corticosterone on splenic T-cell activation: critical role of cell density and culture time. Neuroendocrinology (2001) 0.77

Changes in peripheral blood lymphocyte subsets in elderly subjects are associated with an impaired function of the hypothalamic-pituitary-adrenal axis. Mech Ageing Dev (2002) 0.77

How can we use moderate stresses to fortify humans and slow aging? Sci Aging Knowledge Environ (2005) 0.77