Luc Nelles

Author PubWeight™ 10.73‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mice lacking ZFHX1B, the gene that codes for Smad-interacting protein-1, reveal a role for multiple neural crest cell defects in the etiology of Hirschsprung disease-mental retardation syndrome. Am J Hum Genet 2003 1.88
2 Generation of the floxed allele of the SIP1 (Smad-interacting protein 1) gene for Cre-mediated conditional knockout in the mouse. Genesis 2002 1.34
3 Ttrap is an essential modulator of Smad3-dependent Nodal signaling during zebrafish gastrulation and left-right axis determination. Development 2007 1.29
4 Interaction between Smad-interacting protein-1 and the corepressor C-terminal binding protein is dispensable for transcriptional repression of E-cadherin. J Biol Chem 2003 1.22
5 Preclinical characterization of GLPG0634, a selective inhibitor of JAK1, for the treatment of inflammatory diseases. J Immunol 2013 1.07
6 Neural crest-specific removal of Zfhx1b in mouse leads to a wide range of neurocristopathies reminiscent of Mowat-Wilson syndrome. Hum Mol Genet 2007 0.93
7 Discovery and optimization of an azetidine chemical series as a free fatty acid receptor 2 (FFA2) antagonist: from hit to clinic. J Med Chem 2014 0.85
8 Cloning and expression of the cyclophilin Bet v 7, and analysis of immunological cross-reactivity among the cyclophilin A family. Mol Immunol 2005 0.81
9 Essential validation of gene trap mouse ES cell lines: a test case with the gene Ttrap. Int J Dev Biol 2009 0.80
10 Smicl is a novel Smad interacting protein and cleavage and polyadenylation specificity factor associated protein. Genes Cells 2005 0.80
11 Triazolopyridines as selective JAK1 inhibitors: from hit identification to GLPG0634. J Med Chem 2014 0.76