Pathogenesis and treatment of Shiga toxin-producing Escherichia coli infections.

PubWeight™: 1.28‹?› | Rank: Top 10%

🔗 View Article (PMID 18043231)

Published in Curr Opin Gastroenterol on January 01, 2008

Authors

Antonio Serna1, Edgar C Boedeker

Author Affiliations

1: Division of Gastroenterology/Hepatology, Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM 87131-0001, USA.

Articles citing this

Escherichia coli O157:H7: animal reservoir and sources of human infection. Foodborne Pathog Dis (2010) 2.12

Analysis of the genome of the Escherichia coli O157:H7 2006 spinach-associated outbreak isolate indicates candidate genes that may enhance virulence. Infect Immun (2009) 2.07

Rapid and sensitive detection of Shiga toxin-producing Escherichia coli from nonenriched stool specimens by real-time PCR in comparison to enzyme immunoassay and culture. J Clin Microbiol (2009) 1.69

Monoclonal antibody-based therapies for microbial diseases. Vaccine (2009) 1.47

Macropinocytosis in Shiga toxin 1 uptake by human intestinal epithelial cells and transcellular transcytosis. Am J Physiol Gastrointest Liver Physiol (2008) 1.09

Identification of small-molecule inhibitors of ricin and shiga toxin using a cell-based high-throughput screen. Toxicon (2010) 1.06

Enterohemorrhagic Escherichia coli O157:H7 gene expression profiling in response to growth in the presence of host epithelia. PLoS One (2009) 1.04

Novel cell-based method to detect Shiga toxin 2 from Escherichia coli O157:H7 and inhibitors of toxin activity. Appl Environ Microbiol (2009) 1.00

Therapeutic concentrations of antibiotics inhibit Shiga toxin release from enterohemorrhagic E. coli O104:H4 from the 2011 German outbreak. BMC Microbiol (2012) 0.98

Gnotobiotic piglet infection model for evaluating the safe use of antibiotics against Escherichia coli O157:H7 infection. J Infect Dis (2009) 0.98

Will there ever be a universal Staphylococcus aureus vaccine? Hum Vaccin Immunother (2013) 0.97

Pathogen- and host-directed anti-inflammatory activities of macrolide antibiotics. Mediators Inflamm (2012) 0.95

Hemolytic uremic syndrome: new developments in pathogenesis and treatment. Int J Nephrol (2011) 0.92

Evaluation of Fab and F(ab')2 fragments and isotype variants of a recombinant human monoclonal antibody against Shiga toxin 2. Infect Immun (2010) 0.91

Advances in our understanding of the pathogenesis of glomerular thrombotic microangiopathy. Pediatr Nephrol (2010) 0.89

Antibody response to Shiga toxins in Argentinean children with enteropathic hemolytic uremic syndrome at acute and long-term follow-up periods. PLoS One (2011) 0.86

Underlying mechanism of antimicrobial activity of chitosan microparticles and implications for the treatment of infectious diseases. PLoS One (2014) 0.85

Functional analysis of ycfR and ycfQ in Escherichia coli O157:H7 linked to outbreaks of illness associated with fresh produce. Appl Environ Microbiol (2011) 0.85

Inhibition of development of Shiga toxin-converting bacteriophages by either treatment with citrate or amino acid starvation. Foodborne Pathog Dis (2011) 0.84

Pathogenicity, host responses and implications for management of enterohemorrhagic Escherichia coli O157:H7 infection. Can J Gastroenterol (2013) 0.84

Identification of Escherichia coli O157 by using a novel colorimetric detection method with DNA microarrays. Foodborne Pathog Dis (2011) 0.84

Enterohemorrhagic Escherichia coli suppresses inflammatory response to cytokines and its own toxin. Am J Physiol Gastrointest Liver Physiol (2009) 0.83

Modulation of the enterohemorrhagic E. coli virulence program through the human gastrointestinal tract. Virulence (2013) 0.83

Enterohemorrhagic Escherichia coli infection stimulates Shiga toxin 1 macropinocytosis and transcytosis across intestinal epithelial cells. Am J Physiol Cell Physiol (2011) 0.83

Serine protease EspP from enterohemorrhagic Escherichia coli is sufficient to induce shiga toxin macropinocytosis in intestinal epithelium. PLoS One (2013) 0.82

Escherichia coli O157:H7/NM prevalence in raw beef, camel, sheep, goat, and water buffalo meat in Fars and Khuzestan provinces, Iran. Vet Res Forum (2012) 0.81

Activation of p38α in T cells regulates the intestinal host defense against attaching and effacing bacterial infections. J Immunol (2013) 0.81

Phenethyl isothiocyanate inhibits shiga toxin production in enterohemorrhagic Escherichia coli by stringent response induction. Antimicrob Agents Chemother (2014) 0.79

Shiga toxin 1 interaction with enterocytes causes apical protein mistargeting through the depletion of intracellular galectin-3. Exp Cell Res (2009) 0.78

Beneficial and Harmful Interactions of Antibiotics with Microbial Pathogens and the Host Innate Immune System. Pharmaceuticals (Basel) (2010) 0.75

Type III Secretion-Dependent Sensitivity of Escherichia coli O157 to Specific Ketolides. Antimicrob Agents Chemother (2015) 0.75

A Simple and Rapid Procedure for the Detection of Genes Encoding Shiga Toxins and Other Specific DNA Sequences. Toxins (Basel) (2015) 0.75

Articles by these authors

Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proc Natl Acad Sci U S A (2007) 20.60

The QseC sensor kinase: a bacterial adrenergic receptor. Proc Natl Acad Sci U S A (2006) 3.07

Disease phenotype and genotype are associated with shifts in intestinal-associated microbiota in inflammatory bowel diseases. Inflamm Bowel Dis (2010) 2.62

Inflammatory bowel diseases phenotype, C. difficile and NOD2 genotype are associated with shifts in human ileum associated microbial composition. PLoS One (2012) 1.82

Virulence inhibition by zinc in shiga-toxigenic Escherichia coli. Infect Immun (2011) 1.08

Effect of zinc in enteropathogenic Escherichia coli infection. Infect Immun (2007) 1.05

Protection against hemorrhagic colitis in an animal model by oral immunization with isogeneic rabbit enteropathogenic Escherichia coli attenuated by truncating intimin. Infect Immun (2005) 0.97

Role of host xanthine oxidase in infection due to enteropathogenic and Shiga-toxigenic Escherichia coli. Infect Immun (2013) 0.96

Towards a vaccine for attaching/effacing Escherichia coli: a LEE encoded regulator (ler) mutant of rabbit enteropathogenic Escherichia coli is attenuated, immunogenic, and protects rabbits from lethal challenge with the wild-type virulent strain. Vaccine (2005) 0.94

Use of a continuous-flow anaerobic culture to characterize enteric virulence gene expression. Infect Immun (2004) 0.86

The possible influence of LuxS in the in vivo virulence of rabbit enteropathogenic Escherichia coli. Vet Microbiol (2007) 0.85

Delivery of heterologous protein antigens via hemolysin or autotransporter systems by an attenuated ler mutant of rabbit enteropathogenic Escherichia coli. Vaccine (2005) 0.84

Attenuated Escherichia coli strains expressing the colonization factor antigen I (CFA/I) and a detoxified heat-labile enterotoxin (LThK63) enhance clearance of ETEC from the lungs of mice and protect mice from intestinal ETEC colonization and LT-induced fluid accumulation. Vet Immunol Immunopathol (2012) 0.82

Serine protease EspP from enterohemorrhagic Escherichia coli is sufficient to induce shiga toxin macropinocytosis in intestinal epithelium. PLoS One (2013) 0.82

Development of a live oral attaching and effacing Escherichia coli vaccine candidate using Vibrio cholerae CVD 103-HgR as antigen vector. Microb Pathog (2009) 0.78

Shiga toxin 1 interaction with enterocytes causes apical protein mistargeting through the depletion of intracellular galectin-3. Exp Cell Res (2009) 0.78

Helicobacter pylori infection: treatment. Curr Opin Gastroenterol (2002) 0.77

Gut microbes, the innate immune system and inflammatory bowel disease: location, location, location. Curr Opin Gastroenterol (2007) 0.76

A directed intimin insertion mutant of a rabbit enteropathogenic Escherichia coli (REPEC) is attenuated, immunogenic and elicits serogroup specific protection. Vet Immunol Immunopathol (2012) 0.76

Gastrointestinal infections. Curr Opin Gastroenterol (2003) 0.75

Gastrointestinal infections: an overview. Curr Opin Gastroenterol (2004) 0.75

Correction: Identification of Candidate Adherent-Invasive E. coli Signature Transcripts by Genomic/Transcriptomic Analysis. PLoS One (2015) 0.75

Foodborne enteric infections. Curr Opin Gastroenterol (2003) 0.75