Published in J Agric Food Chem on December 05, 2007
Luteolin and luteolin-7-O-glucoside inhibit lipopolysaccharide-induced inflammatory responses through modulation of NF-κB/AP-1/PI3K-Akt signaling cascades in RAW 264.7 cells. Nutr Res Pract (2013) 0.95
Flavone deglycosylation increases their anti-inflammatory activity and absorption. Mol Nutr Food Res (2012) 0.83
Luteolin is effective in the non-small cell lung cancer model with L858R/T790M EGF receptor mutation and erlotinib resistance. Br J Pharmacol (2014) 0.82
Endocrine disrupting activities of the flavonoid nutraceuticals luteolin and quercetin. Horm Cancer (2013) 0.78
Phytochemicals for the Management of Melanoma. Mini Rev Med Chem (2016) 0.77
The effects of Angelica keiskei Koidz on the expression of antioxidant enzymes related to lipid profiles in rats fed a high fat diet. Nutr Res Pract (2012) 0.77
Preparation and characterization of monomethoxy poly(ethylene glycol)-poly(ε-caprolactone) micelles for the solubilization and in vivo delivery of luteolin. Int J Nanomedicine (2013) 0.77
Flavones: Food Sources, Bioavailability, Metabolism, and Bioactivity. Adv Nutr (2017) 0.75
Identification of the Flavonoid Luteolin as a Repressor of the Transcription Factor Hepatocyte Nuclear Factor 4α. J Biol Chem (2015) 0.75
Hyperglycemia-induced oxidative stress and heart disease-cardioprotective effects of rooibos flavonoids and phenylpyruvic acid-2-O-β-D-glucoside. Nutr Metab (Lond) (2017) 0.75
The ubiquitin-interacting motif containing protein RAP80 interacts with BRCA1 and functions in DNA damage repair response. Cancer Res (2007) 2.43
Human pregnane X receptor and resistance to chemotherapy in prostate cancer. Cancer Res (2007) 1.35
Cellular uptake of solid lipid nanoparticles and cytotoxicity of encapsulated paclitaxel in A549 cancer cells. Int J Pharm (2007) 1.35
Preparation and characterization of stearic acid nanostructured lipid carriers by solvent diffusion method in an aqueous system. Colloids Surf B Biointerfaces (2005) 1.25
Preparation of two sets of 5,6,7-trioxygenated dihydroflavonol derivatives as free radical scavengers and neuronal cell protectors to oxidative damage. Bioorg Med Chem (2009) 1.16
PCR detection and PFGE genotype analyses of streptococcal clinical isolates from tilapia in China. Vet Microbiol (2012) 1.15
A novel chitosan oligosaccharide-stearic acid micelles for gene delivery: properties and in vitro transfection studies. Int J Pharm (2006) 1.14
Shell cross-linked stearic acid grafted chitosan oligosaccharide self-aggregated micelles for controlled release of paclitaxel. Colloids Surf B Biointerfaces (2006) 1.08
Studies on oral absorption of stearic acid SLN by a novel fluorometric method. Colloids Surf B Biointerfaces (2007) 1.04
Preparation and characteristics of monostearin nanostructured lipid carriers. Int J Pharm (2006) 1.01
Nuclear receptors PXR and CAR: implications for drug metabolism regulation, pharmacogenomics and beyond. Expert Opin Drug Metab Toxicol (2013) 1.01
Trends in road traffic crashes and associated injury and fatality in the People's Republic of China, 1951-1999. Inj Control Saf Promot (2003) 1.00
PXR-mediated transcriptional activation of CYP3A4 by cryptotanshinone and tanshinone IIA. Chem Biol Interact (2008) 0.98
Pharmacokinetic drug interaction profile of omeprazole with adverse consequences and clinical risk management. Ther Clin Risk Manag (2013) 0.96
Permeation of astilbin and taxifolin in Caco-2 cell and their effects on the P-gp. Int J Pharm (2009) 0.95
Discrimination analysis of mass spectrometry proteomics for ovarian cancer detection. Acta Pharmacol Sin (2008) 0.94
Preparation and characteristics of nanostructured lipid carriers for control-releasing progesterone by melt-emulsification. Colloids Surf B Biointerfaces (2007) 0.94
Identification of novel pregnane X receptor activators from traditional Chinese medicines. J Ethnopharmacol (2011) 0.94
Cytotoxic, cytoprotective and antioxidant effects of isolated phenolic compounds from fresh ginger. Fitoterapia (2012) 0.94
Metabolomics study on quality control and discrimination of three curcuma species based on gas chromatograph-mass spectrometry. Phytochem Anal (2011) 0.93
Screening vaccine candidate strains against Streptococcus agalactiae of tilapia based on PFGE genotype. Vaccine (2012) 0.92
Enantiomeric separation of 2-arylpropionic acid nonsteroidal anti-inflammatory drugs by HPLC with hydroxypropyl-beta-cyclodextrin as chiral mobile phase additive. Biomed Chromatogr (2010) 0.89
Glucuronidation of flavonoids by recombinant UGT1A3 and UGT1A9. Biochem Pharmacol (2008) 0.89
Distribution and metabolism of gastrodin in rat brain. J Pharm Biomed Anal (2007) 0.89
Estrogen sulfotransferase inhibits adipocyte differentiation. Mol Endocrinol (2011) 0.88
Influence of various polymorphic variants of cytochrome P450 oxidoreductase (POR) on drug metabolic activity of CYP3A4 and CYP2B6. PLoS One (2012) 0.88
Quantitative phosphoproteomics of proteasome inhibition in multiple myeloma cells. PLoS One (2010) 0.87
HPLC analysis of para-aminosalicylic acid and its metabolite in plasma, cerebrospinal fluid and brain tissues. J Pharm Biomed Anal (2010) 0.87
Simvastatin pharmacokinetics in healthy Chinese subjects and its relations with CYP2C9, CYP3A5, ABCB1, ABCG2 and SLCO1B1 polymorphisms. Pharmazie (2013) 0.86
CYP2C9*3(1075A > C), ABCB1 and SLCO1B1 genetic polymorphisms and gender are determinants of inter-subject variability in pitavastatin pharmacokinetics. Pharmazie (2013) 0.86
Investigation on modulation of human P-gp by multiple doses of Radix Astragali extract granules using fexofenadine as a phenotyping probe. J Ethnopharmacol (2013) 0.86
Determination of gemcitabine and its metabolite in human plasma using high-pressure liquid chromatography coupled with a diode array detector. Acta Pharmacol Sin (2004) 0.85
Enantioselective plasma protein binding of propafenone: mechanism, drug interaction, and species difference. Chirality (2009) 0.85
Stereoselective propranolol metabolism in two drug induced rat hepatic microsomes. World J Gastroenterol (2000) 0.85
Absorption and excretion of luteolin and apigenin in rats after oral administration of Chrysanthemum morifolium extract. J Agric Food Chem (2007) 0.85
Nuclear localization of annexin A1 correlates with advanced disease and peritoneal dissemination in patients with gastric carcinoma. Anat Rec (Hoboken) (2010) 0.85
Rational prescription of drugs within similar therapeutic or structural class for gastrointestinal disease treatment: drug metabolism and its related interactions. World J Gastroenterol (2007) 0.85
Design, synthesis, and examination of neuron protective properties of alkenylated and amidated dehydro-silybin derivatives. J Med Chem (2009) 0.85
Salvia miltiorrhiza attenuates the changes in contraction and intracellular calcium induced by anoxia and reoxygenation in rat cardiomyocytes. Life Sci (2003) 0.85
Characterizing the effect of UDP-glucuronosyltransferase (UGT) 2B7 and UGT1A9 genetic polymorphisms on enantioselective glucuronidation of flurbiprofen. Biochem Pharmacol (2011) 0.85
The two enantiomers of tetrahydropalmatine are inhibitors of P-gp, but not inhibitors of MRP1 or BCRP. Xenobiotica (2012) 0.84
Crystal structure and nucleotide selectivity of human IFIT5/ISG58. Cell Res (2013) 0.84
Role of catechol-O-methyltransferase in the disposition of luteolin in rats. Drug Metab Dispos (2011) 0.84
Carboxyl-glucuronidation of mitiglinide by human UDP-glucuronosyltransferases. Biochem Pharmacol (2007) 0.83
Effects of exogenous salicylic acid on growth and H2O2-metabolizing enzymes in rice seedlings under lead stress. J Environ Sci (China) (2007) 0.83
[Effect and mechanism of L-arginine therapy for fetal growth retardation due to pregnancy-induced hypertension]. Nan Fang Yi Ke Da Xue Xue Bao (2007) 0.83
Preparation of C-23 esterified silybin derivatives and evaluation of their lipid peroxidation inhibitory and DNA protective properties. Bioorg Med Chem (2009) 0.83
Solid lipid nanoparticles prepared by solvent diffusion method in a nanoreactor system. Colloids Surf B Biointerfaces (2007) 0.83
Antioxidant action of a Chrysanthemum morifolium extract protects rat brain against ischemia and reperfusion injury. J Med Food (2010) 0.82
Involvement of annexin A1 in multidrug resistance of K562/ADR cells identified by the proteomic study. OMICS (2009) 0.82
Stereoselective binding of chiral drugs to plasma proteins. Acta Pharmacol Sin (2013) 0.82
Determination of enantiomeric impurity in besifloxacin hydrochloride by chiral high-performance liquid chromatography with precolumn derivatization. Chirality (2012) 0.82
Application of a liquid chromatography-tandem mass spectrometry method to the pharmacokinetics, tissue distribution and excretion studies of Dactylicapnos scandens in rats. J Pharm Biomed Anal (2012) 0.82
[The anti-injury effect of breviscapine injection on the hypoxic ischemic brain damage of neonatal rats and the expression of Bcl-2 and Bax]. Zhongguo Ying Yong Sheng Li Xue Za Zhi (2011) 0.81
The exposure of luteolin is much lower than that of apigenin in oral administration of Flos Chrysanthemi extract to rats. Drug Metab Pharmacokinet (2011) 0.81
Transport characteristics of zolmitriptan in a human intestinal epithelial cell line Caco-2. J Pharm Pharmacol (2007) 0.81
An overview of ABC and SLC drug transporter gene regulation. Curr Drug Metab (2013) 0.81
[Research progress of zebrafish used in drug metabolism]. Yao Xue Xue Bao (2011) 0.81
Involvement of AP-1 and NF-κB in the up-regulation of P-gp in vinblastine resistant Caco-2 cells. Drug Metab Pharmacokinet (2013) 0.81
Effects of stereochemical aspects on drug interaction in pharmacokinetics. Acta Pharmacol Sin (2002) 0.81
Stereoselective protein binding of tetrahydropalmatine enantiomers in human plasma, HSA, and AGP, but not in rat plasma. Chirality (2010) 0.81
Structure-metabolism relationships for the glucuronidation of flavonoids by UGT1A3 and UGT1A9. J Pharm Pharmacol (2010) 0.80
Isoform-selective inhibition of chrysin towards human cytochrome P450 1A2. Kinetics analysis, molecular docking, and molecular dynamics simulations. Bioorg Med Chem Lett (2010) 0.80
Determination and assay validation of luteolin and apigenin in human urine after oral administration of tablet of Chrysanthemum morifolium extract by HPLC. J Pharm Biomed Anal (2005) 0.80
ABCB1 gene polymorphisms, ABCB1 haplotypes and ABCG2 c.421c > A are determinants of inter-subject variability in rosuvastatin pharmacokinetics. Pharmazie (2013) 0.80
[Effects of microsome enzyme induced by phenobarbarbital on the stereoselectivity of recemic propranolol glucuronidation metabolism]. Zhejiang Da Xue Xue Bao Yi Xue Ban (2004) 0.80
Enantiomeric separation of norgestrel by reversed phase high-performance liquid chromatography using eluents containing hydroxypropyl-beta-cyclodextrin in stereoselective skin permeation study. J Chromatogr B Analyt Technol Biomed Life Sci (2006) 0.80
Pharmacokinetics of Gastrodin in rat plasma and CSF after i.n. and i.v. Int J Pharm (2007) 0.80
Expression of proton-coupled oligopeptide transporter (POTs) in prostate of mice and patients with benign prostatic hyperplasia (BPH) and prostate cancer (PCa). Prostate (2012) 0.80
Roles of UDP-glucuronosyltransferases in phytochemical metabolism of herbal medicines and the associated herb-drug interactions. Curr Drug Metab (2012) 0.80
Simultaneous determination of quercetin, kaempferol and isorhamnetin accumulated human breast cancer cells, by high-performance liquid chromatography. J Pharm Biomed Anal (2005) 0.80
Stereoselective transport and uptake of propranolol across human intestinal Caco-2 cell monolayers. Chirality (2010) 0.80
Analysis of flurbiprofen, ketoprofen and etodolac enantiomers by pre-column derivatization RP-HPLC and application to drug-protein binding in human plasma. J Pharm Biomed Anal (2008) 0.80
Dual effects of hydrogen sulphide on focal cerebral ischaemic injury via modulation of oxidative stress-induced apoptosis. Clin Exp Pharmacol Physiol (2012) 0.80
Direct determination of S-(-)- and R-(+)-propranolol glucuronide in rat hepatic microsomes by RP-HPLC. Biomed Chromatogr (2004) 0.80
Lentiviral transgenic microRNA-based shRNA suppressed mouse cytochromosome P450 3A (CYP3A) expression in a dose-dependent and inheritable manner. PLoS One (2012) 0.79
Simultaneous determination of luteolin and apigenin in dog plasma by RP-HPLC. J Pharm Biomed Anal (2004) 0.79
Detection of phenolic metabolites of styrene in mouse liver and lung microsomal incubations. Drug Metab Dispos (2010) 0.79
Garcinia xanthones as orally active antitumor agents. J Med Chem (2012) 0.79
[Establishment of MDCK cell models expressing human MATE1 or co-expressing with human OCT1 or OCT2]. Yao Xue Xue Bao (2015) 0.79
Brain regional pharmacokinetics of p-aminosalicylic acid and its N-acetylated metabolite: effectiveness in chelating brain manganese. Drug Metab Dispos (2011) 0.79
Genetic variants of human UGT1A3: functional characterization and frequency distribution in a Chinese Han population. Drug Metab Dispos (2006) 0.79
Simultaneous determination of phenylglyoxylic acid, mandelic acid, styrene glycol and hippuric acid in primary culture of rat hepatocytes incubate by high-performance liquid chromatography. Biomed Chromatogr (2007) 0.79
Relative contribution of small and large intestine to deglycosylation and absorption of flavonoids from Chrysanthemun morifolium extract. J Agric Food Chem (2010) 0.79
Rapid determination of isocorydine in rat plasma and tissues using liquid chromatography--tandem mass spectrometry and its applications to pharmacokinetics and tissue distribution. Xenobiotica (2012) 0.79
Involvement of P-glycoprotein in regulating cellular levels of Ginkgo flavonols: quercetin, kaempferol, and isorhamnetin. J Pharm Pharmacol (2005) 0.79
Chemotherapeutic effects of bioassay-guided extracts of the American cockroach, Periplaneta americana. Integr Cancer Ther (2011) 0.79
Evaluation of pluronic nanosuspensions loading a novel insoluble anticancer drug both in vitro and in vivo. Int J Pharm (2013) 0.78
Carbon-carbon double-bond reductases in nature. Drug Metab Rev (2014) 0.78
Fragmentation study on the phenolic alkaloid neferine and its analogues with anti-HIV activities by electrospray ionization tandem mass spectrometry with hydrogen/deuterium exchange and its application for rapid identification of in vitro microsomal metabolites of neferine. Rapid Commun Mass Spectrom (2007) 0.78
Organic cation transporter 1 mediates the uptake of monocrotaline and plays an important role in its hepatotoxicity. Toxicology (2013) 0.78
Poor awareness of preventing aspirin-induced gastrointestinal injury with combined protective medications. World J Gastroenterol (2012) 0.78
Enantioselective drug-protein interaction between mexiletine and plasma protein. J Pharm Pharmacol (2012) 0.78
Development of enantioselective polyclonal antibodies to detect styrene oxide protein adducts. Anal Chem (2009) 0.78
Stereoselective accumulation of propranolol enantiomers in K562 and K562/ADR cells. Chirality (2013) 0.78
Male-specific induction of CYP3A2 in rats by zolmitriptan. J Pharm Pharmacol (2008) 0.78