Contributions of capillary electrophoresis to neuroscience.

PubWeight™: 1.76‹?› | Rank: Top 3%

🔗 View Article (PMID 18054026)

Published in J Chromatogr A on November 05, 2007

Authors

Theodore Lapainis1, Jonathan V Sweedler

Author Affiliations

1: Department of Chemistry, University of Illinois at Urbana-Champaign, 600 South Mathews Avenue, Urbana, IL 61801, USA.

Articles citing this

Chemical analysis of single cells. Anal Chem (2011) 1.14

Patch clamp electrophysiology and capillary electrophoresis-mass spectrometry metabolomics for single cell characterization. Anal Chem (2014) 1.06

Enhanced neuropeptide profiling via capillary electrophoresis off-line coupled with MALDI FTMS. Anal Chem (2008) 1.05

Capillary electrophoresis applied to proteomic analysis. J Sep Sci (2009) 1.03

Single-cell metabolomics: changes in the metabolome of freshly isolated and cultured neurons. ACS Chem Neurosci (2012) 1.00

Qualitative and quantitative metabolomic investigation of single neurons by capillary electrophoresis electrospray ionization mass spectrometry. Nat Protoc (2013) 0.97

Combining capillary electrophoresis matrix-assisted laser desorption/ionization mass spectrometry and stable isotopic labeling techniques for comparative crustacean peptidomics. J Chromatogr A (2010) 0.96

Advancing matrix-assisted laser desorption/ionization-mass spectrometric imaging for capillary electrophoresis analysis of peptides. Anal Chem (2011) 0.90

Microfluidic device for the selective chemical stimulation of neurons and characterization of peptide release with mass spectrometry. Anal Chem (2012) 0.88

D-Aspartate acts as a signaling molecule in nervous and neuroendocrine systems. Amino Acids (2012) 0.87

A hyphenated optical trap capillary electrophoresis laser induced native fluorescence system for single-cell chemical analysis. Analyst (2012) 0.85

Pressure-assisted capillary electrophoresis coupling with matrix-assisted laser desorption/ionization-mass spectrometric imaging for quantitative analysis of complex peptide mixtures. Anal Chem (2012) 0.85

Neuropeptide analysis with liquid chromatography-capillary electrophoresis-mass spectrometric imaging. J Sep Sci (2012) 0.84

Combining tissue extraction and off-line capillary electrophoresis matrix-assisted laser desorption/ionization Fourier transform mass spectrometry for neuropeptide analysis in individual neuronal organs using 2,5-dihydroxybenzoic acid as a multi-functional agent. J Chromatogr A (2009) 0.82

A novel pyridoxal 5'-phosphate-dependent amino acid racemase in the Aplysia californica central nervous system. J Biol Chem (2011) 0.82

Mass spectrometry-based characterization of endogenous peptides and metabolites in small volume samples. Biochim Biophys Acta (2015) 0.82

Signals from the brainstem sleep/wake centers regulate behavioral timing via the circadian clock. PLoS One (2013) 0.81

Analysis of endogenous nucleotides by single cell capillary electrophoresis-mass spectrometry. Analyst (2014) 0.81

Automated method for analysis of tryptophan and tyrosine metabolites using capillary electrophoresis with native fluorescence detection. Anal Bioanal Chem (2013) 0.80

Analysis of superoxide production in single skeletal muscle fibers. Anal Chem (2010) 0.79

Editorial on "Contributions of capillary electrophoresis to neuroscience" by T. Lapainis and J.V. Sweedler. J Chromatogr A (2007) 0.75

Strategies for Fostering Synergy between Neuroscience Programs and Chemistry Departments. J Undergrad Neurosci Educ (2011) 0.75

D-Alanine in the islets of Langerhans of rat pancreas. Biochem Biophys Res Commun (2014) 0.75

Quantitative determination of free D-Asp, L-Asp and N-methyl-D-aspartate in mouse brain tissues by chiral separation and Multiple Reaction Monitoring tandem mass spectrometry. PLoS One (2017) 0.75

Articles by these authors

(truncated to the top 100)

The genome sequence of taurine cattle: a window to ruminant biology and evolution. Science (2009) 8.23

Analyses of pig genomes provide insight into porcine demography and evolution. Nature (2012) 5.58

Genome-wide analyses reveal a role for peptide hormones in planarian germline development. PLoS Biol (2010) 2.47

From the genome to the proteome: uncovering peptides in the Apis brain. Science (2006) 2.25

MALDI-MS imaging of features smaller than the size of the laser beam. J Am Soc Mass Spectrom (2005) 2.08

Circadian rhythm of redox state regulates excitability in suprachiasmatic nucleus neurons. Science (2012) 1.97

Peptides in the brain: mass spectrometry-based measurement approaches and challenges. Annu Rev Anal Chem (Palo Alto Calif) (2008) 1.92

The Enzyme Function Initiative. Biochemistry (2011) 1.87

Storage and uptake of D-serine into astrocytic synaptic-like vesicles specify gliotransmission. J Neurosci (2013) 1.82

Profiling metabolites and peptides in single cells. Nat Methods (2011) 1.79

Microfluidic devices for culturing primary mammalian neurons at low densities. Lab Chip (2007) 1.68

Discovering new invertebrate neuropeptides using mass spectrometry. Mass Spectrom Rev (2005) 1.66

Micromixer-based time-resolved NMR: applications to ubiquitin protein conformation. Anal Chem (2003) 1.64

Vitamin E imaging and localization in the neuronal membrane. J Am Chem Soc (2005) 1.52

Targeted single-cell microchemical analysis: MS-based peptidomics of individual paraformaldehyde-fixed and immunolabeled neurons. Chem Biol (2012) 1.51

Imaging mass spectrometry: fundamentals and applications to drug discovery. Drug Discov Today (2005) 1.47

Discovery of new enzymes and metabolic pathways by using structure and genome context. Nature (2013) 1.46

Discrete molecular states in the brain accompany changing responses to a vocal signal. Proc Natl Acad Sci U S A (2009) 1.46

NeuroPred: a tool to predict cleavage sites in neuropeptide precursors and provide the masses of the resulting peptides. Nucleic Acids Res (2006) 1.45

Profiling signaling peptides in single mammalian cells using mass spectrometry. Anal Chem (2006) 1.38

Gateable nanofluidic interconnects for multilayered microfluidic separation systems. Anal Chem (2003) 1.30

From hunger to satiety: reconfiguration of a feeding network by Aplysia neuropeptide Y. J Neurosci (2007) 1.30

Mass spectrometric investigation of the neuropeptide complement and release in the pericardial organs of the crab, Cancer borealis. J Neurochem (2003) 1.28

Mass spectrometry-based discovery of circadian peptides. Proc Natl Acad Sci U S A (2008) 1.27

Spatial profiling with MALDI MS: distribution of neuropeptides within single neurons. Anal Chem (2003) 1.26

Microproteomics: analysis of protein diversity in small samples. Mass Spectrom Rev (2008) 1.26

Spatial profiling invertebrate ganglia using MALDI MS. J Am Soc Mass Spectrom (2003) 1.24

Quantitative peptidomics reveal brain peptide signatures of behavior. Proc Natl Acad Sci U S A (2009) 1.21

Bridging neuropeptidomics and genomics with bioinformatics: Prediction of mammalian neuropeptide prohormone processing. J Proteome Res (2006) 1.21

A protease for 'middle-down' proteomics. Nat Methods (2012) 1.19

Capillary electrophoresis with electrospray ionization mass spectrometric detection for single-cell metabolomics. Anal Chem (2009) 1.19

Progress toward single cell metabolomics. Curr Opin Biotechnol (2012) 1.19

Mass spectrometry imaging and profiling of single cells. J Proteomics (2012) 1.17

Glial D-serine gates NMDA receptors at excitatory synapses in prefrontal cortex. Cereb Cortex (2011) 1.15

Characterizing peptides in individual mammalian cells using mass spectrometry. Nat Protoc (2007) 1.15

Metabolic differentiation of neuronal phenotypes by single-cell capillary electrophoresis-electrospray ionization-mass spectrometry. Anal Chem (2011) 1.14

A RubisCO-like protein links SAM metabolism with isoprenoid biosynthesis. Nat Chem Biol (2012) 1.13

Neuropeptidomics of the supraoptic rat nucleus. J Proteome Res (2008) 1.13

Quantitative measurements of cell-cell signaling peptides with single-cell MALDI MS. Anal Chem (2008) 1.10

Design and fabrication of a multilayered polymer microfluidic chip with nanofluidic interconnects via adhesive contact printing. Lab Chip (2006) 1.10

Single-neuron analysis using CE combined with MALDI MS and radionuclide detection. Anal Chem (2002) 1.09

Orcokinin peptides in developing and adult crustacean stomatogastric nervous systems and pericardial organs. J Comp Neurol (2002) 1.09

SIMS and MALDI MS imaging of the spinal cord. Proteomics (2008) 1.08

Endogenous peptide discovery of the rat circadian clock: a focused study of the suprachiasmatic nucleus by ultrahigh performance tandem mass spectrometry. Mol Cell Proteomics (2009) 1.08

Nanocapillary array interconnects for gated analyte injections and electrophoretic separations in multilayer microfluidic architectures. Anal Chem (2003) 1.07

Patch clamp electrophysiology and capillary electrophoresis-mass spectrometry metabolomics for single cell characterization. Anal Chem (2014) 1.06

Mass spectrometric imaging of peptide release from neuronal cells within microfluidic devices. Lab Chip (2007) 1.03

From precursor to final peptides: a statistical sequence-based approach to predicting prohormone processing. J Proteome Res (2003) 1.03

Intraspecific variation of venom injected by fish-hunting Conus snails. J Exp Biol (2005) 1.02

Circadian integration of glutamatergic signals by little SAAS in novel suprachiasmatic circuits. PLoS One (2010) 1.02

Massively parallel sample preparation for the MALDI MS analyses of tissues. Anal Chem (2006) 1.00

Molecular organization of Drosophila neuroendocrine cells by Dimmed. Curr Biol (2011) 1.00

Single-cell metabolomics: changes in the metabolome of freshly isolated and cultured neurons. ACS Chem Neurosci (2012) 1.00

Determining sequences and post-translational modifications of novel conotoxins in Conus victoriae using cDNA sequencing and mass spectrometry. J Mass Spectrom (2004) 1.00

Microfluidic separation and gateable fraction collection for mass-limited samples. Anal Chem (2004) 0.99

Prediction of neuropeptide prohormone cleavages with application to RFamides. Peptides (2006) 0.99

The zebra finch neuropeptidome: prediction, detection and expression. BMC Biol (2010) 0.99

Interfering with nitric oxide measurements. 4,5-diaminofluorescein reacts with dehydroascorbic acid and ascorbic acid. J Biol Chem (2002) 0.99

Engineering the morphology and electrophysiological parameters of cultured neurons by microfluidic surface patterning. FASEB J (2004) 0.98

Aplysia bag cells function as a distributed neurosecretory network. J Neurophysiol (2007) 0.98

Feedforward compensation mediated by the central and peripheral actions of a single neuropeptide discovered using representational difference analysis. J Neurosci (2010) 0.97

Qualitative and quantitative metabolomic investigation of single neurons by capillary electrophoresis electrospray ionization mass spectrometry. Nat Protoc (2013) 0.97

Profiling pH gradients across nanocapillary array membranes connecting microfluidic channels. J Am Chem Soc (2005) 0.97

MALDI mass spectrometric imaging using the stretched sample method to reveal neuropeptide distributions in aplysia nervous tissue. Anal Chem (2009) 0.97

An enhanced protein crosslink identification strategy using CID-cleavable chemical crosslinkers and LC/MS(n) analysis. Proteomics (2012) 0.96

monitoring activity-dependent peptide release from the CNS using single-bead solid-phase extraction and MALDI TOF MS detection. Anal Chem (2005) 0.95

Composite modulatory feedforward loop contributes to the establishment of a network state. J Neurophysiol (2010) 0.95

Chapter 13: Imaging of cells and tissues with mass spectrometry: adding chemical information to imaging. Methods Cell Biol (2008) 0.95

Single-cell analysis by capillary electrophoresis. Anal Bioanal Chem (2002) 0.94

Label-free quantitation of peptide release from neurons in a microfluidic device with mass spectrometry imaging. Lab Chip (2012) 0.94

Distinguishing endogenous D-amino acid-containing neuropeptides in individual neurons using tandem mass spectrometry. Anal Chem (2011) 0.94

Prediction of neuropeptide cleavage sites in insects. Bioinformatics (2008) 0.94

Adapting the stretched sample method from tissue profiling to imaging. Proteomics (2008) 0.94

Nanofluidics in chemical analysis. Chem Soc Rev (2009) 0.94

Secondary ion mass spectrometry imaging of molecular distributions in cultured neurons and their processes: comparative analysis of sample preparation. J Am Soc Mass Spectrom (2012) 0.94

Sequencing and mass profiling highly modified conotoxins using global reduction/alkylation followed by mass spectrometry. Anal Chem (2004) 0.93

Anatomical correlates of venom production in Conus californicus. Biol Bull (2002) 0.93

MALDI-guided SIMS: multiscale imaging of metabolites in bacterial biofilms. Anal Chem (2014) 0.93

Comparative analysis of neuropeptide cleavage sites in human, mouse, rat, and cattle. Mamm Genome (2008) 0.93

Detection of nitric oxide in single cells. Analyst (2008) 0.93

Biomolecular imaging with a C60-SIMS/MALDI dual ion source hybrid mass spectrometer: instrumentation, matrix enhancement, and single cell analysis. J Am Soc Mass Spectrom (2014) 0.93

Confirmation of peak assignments in capillary electrophoresis using immunoprecipitation. Application to D-aspartate measurements in neurons. J Chromatogr A (2005) 0.92

MALDI mass spectrometry imaging of neuronal cell cultures. J Am Soc Mass Spectrom (2011) 0.92

One-step sampling, extraction, and storage protocol for peptidomics using dihydroxybenzoic Acid. Anal Chem (2008) 0.92

Screening for post-translational modifications in conotoxins using liquid chromatography/mass spectrometry: an important component of conotoxin discovery. Toxicon (2006) 0.92

Characterization of Aplysia enticin and temptin, two novel water-borne protein pheromones that act in concert with attractin to stimulate mate attraction. J Biol Chem (2004) 0.91

Microfluidic systems for studying neurotransmitters and neurotransmission. Lab Chip (2013) 0.91

Measurement of nitric oxide by 4,5-diaminofluorescein without interferences. Analyst (2004) 0.91

Measuring D-amino acid-containing neuropeptides with capillary electrophoresis. Analyst (2005) 0.91

Neuropeptide precursors in Tribolium castaneum. Peptides (2007) 0.91

Distinct mechanisms produce functionally complementary actions of neuropeptides that are structurally related but derived from different precursors. J Neurosci (2010) 0.91

Miniaturized lead sensor based on lead-specific DNAzyme in a nanocapillary interconnected microfluidic device. Environ Sci Technol (2005) 0.90

Correlated imaging with C60-SIMS and confocal Raman microscopy: Visualization of cell-scale molecular distributions in bacterial biofilms. Anal Chem (2014) 0.90

D-Aspartate as a putative cell-cell signaling molecule in the Aplysia californica central nervous system. J Neurochem (2006) 0.90

Structural and functional analysis of Aplysia attractins, a family of water-borne protein pheromones with interspecific attractiveness. Proc Natl Acad Sci U S A (2004) 0.90

Ultrafast capillary electrophoresis and bioanalytical applications. Proc Natl Acad Sci U S A (2003) 0.90

Analysis of Endogenous D-Amino Acid-Containing Peptides in Metazoa. Bioanal Rev (2009) 0.89

Direct single cell determination of nitric oxide synthase related metabolites in identified nitrergic neurons. J Inorg Biochem (2005) 0.89

Neuropeptide Release is Impaired in a Mouse Model of Fragile X Mental Retardation Syndrome. ACS Chem Neurosci (2010) 0.89

Correlated imaging--a grand challenge in chemical analysis. Analyst (2013) 0.89