Published in Semin Nephrol on November 01, 2007
Uremic solutes and risk of end-stage renal disease in type 2 diabetes: metabolomic study. Kidney Int (2014) 1.80
A basic science view of acute kidney injury biomarkers. Nephrol Dial Transplant (2014) 1.33
Systems biology of kidney diseases. Kidney Int (2011) 1.05
Plasma metabolomic profiles in different stages of CKD. Clin J Am Soc Nephrol (2012) 0.98
Identification of agents that reduce renal hypoxia-reoxygenation injury using cell-based screening: purine nucleosides are alternative energy sources in LLC-PK1 cells during hypoxia. Arch Biochem Biophys (2011) 0.92
Biomarkers of acute kidney injury. J Toxicol (2011) 0.90
Changes in metabolic profiles during acute kidney injury and recovery following ischemia/reperfusion. PLoS One (2014) 0.89
Metabolomics of oxidative stress in recent studies of endogenous and exogenously administered intermediate metabolites. Int J Mol Sci (2011) 0.84
The primary glomerulonephritides: a systems biology approach. Nat Rev Nephrol (2013) 0.82
Biomarkers in chronic kidney disease, from kidney function to kidney damage. World J Nephrol (2015) 0.82
Rule-Mining for the Early Prediction of Chronic Kidney Disease Based on Metabolomics and Multi-Source Data. PLoS One (2016) 0.79
Early lipid changes in acute kidney injury using SWATH lipidomics coupled with MALDI tissue imaging. Am J Physiol Renal Physiol (2016) 0.78
The potential use of biomarkers in predicting contrast-induced acute kidney injury. Int J Nephrol Renovasc Dis (2016) 0.77
Renal Medulla is More Sensitive to Cisplatin than Cortex Revealed by Untargeted Mass Spectrometry-Based Metabolomics in Rats. Sci Rep (2017) 0.76
Fibrates protect against vascular endothelial dysfunction induced by paclitaxel and carboplatin chemotherapy for cancer patients: a pilot study. Int J Clin Oncol (2014) 0.75
Comprehensive renal function evaluation in patients treated for synchronous bilateral Wilms tumor. J Pediatr Surg (2016) 0.75
Metabolomics--the link between genotypes and phenotypes. Plant Mol Biol (2002) 11.36
'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica (1999) 9.04
GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks. Nat Cell Biol (2006) 6.36
A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations. Nat Biotechnol (2001) 4.66
Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor alpha-deficient mice. J Biol Chem (1997) 2.18
Fibrates downregulate apolipoprotein C-III expression independent of induction of peroxisomal acyl coenzyme A oxidase. A potential mechanism for the hypolipidemic action of fibrates. J Clin Invest (1995) 1.88
The role and mode of action of apolipoproteins CIII and AV: synergistic actors in triglyceride metabolism? Curr Opin Lipidol (2004) 1.73
Cisplatin-induced nephrotoxicity is associated with oxidative stress, redox state unbalance, impairment of energetic metabolism and apoptosis in rat kidney mitochondria. Arch Toxicol (2007) 1.53
Protein kinase C epsilon signaling complexes include metabolism- and transcription/translation-related proteins: complimentary separation techniques with LC/MS/MS. Mol Cell Proteomics (2002) 1.44
Selenium and high dose vitamin E administration protects cisplatin-induced oxidative damage to renal, liver and lens tissues in rats. Toxicology (2004) 1.42
Mechanistic biomarkers for cytotoxic acute kidney injury. Expert Opin Drug Metab Toxicol (2006) 1.24
Peroxisome proliferator-activated receptor (PPAR)-alpha activation prevents diabetes in OLETF rats: comparison with PPAR-gamma activation. Diabetes (2003) 1.10
Protection of renal cells from cisplatin toxicity by cell cycle inhibitors. Am J Physiol Renal Physiol (2003) 1.07
Metabolomic study of cisplatin-induced nephrotoxicity. Kidney Int (2006) 1.04
Metabonomics with 1H-NMR spectroscopy and liquid chromatography-mass spectrometry applied to the investigation of metabolic changes caused by gentamicin-induced nephrotoxicity in the rat. Biomarkers (2005) 1.03
Role of the PPAR family of nuclear receptors in the regulation of metabolic and cardiovascular homeostasis: new approaches to therapy. Curr Opin Pharmacol (2005) 1.03
PPAR alpha ligand protects during cisplatin-induced acute renal failure by preventing inhibition of renal FAO and PDC activity. Am J Physiol Renal Physiol (2003) 1.00
Tryptophan-NAD+ pathway metabolites as putative biomarkers and predictors of peroxisome proliferation. Arch Toxicol (2004) 0.98
Fibrate prevents cisplatin-induced proximal tubule cell death. Kidney Int (2005) 0.98
An integrated study of acute effects of valproic acid in the liver using metabonomics, proteomics, and transcriptomics platforms. OMICS (2006) 0.91
1H NMR pattern recognition and 31P NMR studies with d-Serine in rat urine and kidney, time- and dose-related metabolic effects. Chem Res Toxicol (2003) 0.89
Hyperlipidaemia in cisplatin-induced nephrotic rats. Hum Exp Toxicol (1999) 0.84
Regulation of renal amino acid (AA) transport by hormones, drugs and xenobiotics - a review. Amino Acids (2003) 0.83
Bezafibrate, a peroxisome proliferator-activated receptor (PPAR)-alpha activator, prevents pancreatic degeneration in obese and diabetic rats. Pancreas (2003) 0.81
Pancreatic islet response to hyperglycemia is dependent on peroxisome proliferator-activated receptor alpha (PPARalpha). FEBS Lett (2005) 0.81
The effects of cisplatin and other divalent platinum compounds on glucose metabolism and pancreatic endocrine function. Toxicol Appl Pharmacol (1983) 0.79
Investigation of the role of hyperbaric oxygen therapy in cisplatin-induced nephrotoxicity in rats. Arch Toxicol (2004) 0.79
Glucose intolerance following cis-platinum treatment in rats. Toxicology (1982) 0.78
Aminoglycoside antibiotics reduce glucose reabsorption in kidney through down-regulation of SGLT1. Biochem Biophys Res Commun (2003) 0.78
Renal amino acid transport in immature and adult rats during chromate and cisplatinum-induced nephrotoxicity. Amino Acids (2001) 0.78
Summary recommendations for standardization and reporting of metabolic analyses. Nat Biotechnol (2005) 2.90
Deletion of LOX-1 reduces atherogenesis in LDLR knockout mice fed high cholesterol diet. Circ Res (2007) 2.87
Serum metabolomic profiles from patients with acute kidney injury: a pilot study. J Chromatogr B Analyt Technol Biomed Life Sci (2012) 1.55
Structure and dynamics of thioguanine-modified duplex DNA. J Biol Chem (2002) 1.18
Regulation of autophagy and apoptosis in response to ox-LDL in vascular smooth muscle cells, and the modulatory effects of the microRNA hsa-let-7 g. Int J Cardiol (2013) 1.15
Monitoring the health to disease continuum with global metabolic profiling and systems biology. Pharmacogenomics (2006) 1.11
The utility of a rodent model in detecting pediatric drug-induced nephrotoxicity. Toxicol Sci (2007) 0.97
Metabonomics evaluations of age-related changes in the urinary compositions of male Sprague Dawley rats and effects of data normalization methods on statistical and quantitative analysis. BMC Bioinformatics (2007) 0.94
Metabonomics evaluation of urine from rats given acute and chronic doses of acetaminophen using NMR and UPLC/MS. J Chromatogr B Analyt Technol Biomed Life Sci (2008) 0.93
The liver toxicity biomarker study: phase I design and preliminary results. Toxicol Pathol (2009) 0.93
Targeted liquid chromatography-mass spectrometry analysis of serum acylcarnitines in acetaminophen toxicity in children. Biomark Med (2014) 0.93
Variations in metabolism of the soy isoflavonoid daidzein by human intestinal microfloras from different individuals. Arch Microbiol (2003) 0.92
Riddelliine N-oxide is a phytochemical and mammalian metabolite with genotoxic activity that is comparable to the parent pyrrolizidine alkaloid riddelliine. Toxicol Lett (2003) 0.92
An integrated study of acute effects of valproic acid in the liver using metabonomics, proteomics, and transcriptomics platforms. OMICS (2006) 0.91
Gene expression profiles in fathead minnow exposed to 2,4-DNT: correlation with toxicity in mammals. Toxicol Sci (2006) 0.91
In vitro cytotoxicity of nonpolar constituents from different parts of kava plant (Piper methysticum). J Agric Food Chem (2006) 0.91
Quantitation of carcinogenic heterocyclic aromatic amines and detection of novel heterocyclic aromatic amines in cooked meats and grill scrapings by HPLC/ESI-MS. J Agric Food Chem (2005) 0.89
CERAPP: Collaborative Estrogen Receptor Activity Prediction Project. Environ Health Perspect (2016) 0.87
Isolation of an anaerobic intestinal bacterium capable of cleaving the C-ring of the isoflavonoid daidzein. Arch Microbiol (2002) 0.87
Metabolomics evaluation of the effects of green tea extract on acetaminophen-induced hepatotoxicity in mice. Food Chem Toxicol (2013) 0.86
Differential gene expression in mouse liver associated with the hepatoprotective effect of clofibrate. Toxicol Appl Pharmacol (2007) 0.85
Age-related differences in susceptibility to toxic effects of valproic acid in rats. J Appl Toxicol (2008) 0.84
Methylation potential associated with diet, genotype, protein, and metabolite levels in the Delta Obesity Vitamin Study. Genes Nutr (2014) 0.84
Identification of metabolite profiles of the catechol-O-methyl transferase inhibitor tolcapone in rat urine using LC/MS-based metabonomics analysis. J Chromatogr B Analyt Technol Biomed Life Sci (2009) 0.83
Metabolic activation of the tumorigenic pyrrolizidine alkaloid, monocrotaline, leading to DNA adduct formation in vivo. Cancer Lett (2004) 0.83
Study of valproic acid-induced endogenous and exogenous metabolite alterations using LC-MS-based metabolomics. Bioanalysis (2010) 0.82
Genomic and metabolomic advances in the identification of disease and adverse event biomarkers. Biomark Med (2009) 0.82
Assessment of usnic acid toxicity in rat primary hepatocytes using ¹³C isotopomer distribution analysis of lactate, glutamate and glucose. Food Chem Toxicol (2011) 0.82
In vitro metabolism of hyperforin in rat liver microsomal systems. Drug Metab Dispos (2004) 0.81
Studies of acetaminophen and metabolites in urine and their correlations with toxicity using metabolomics. Drug Metab Lett (2009) 0.81
¹³C NMR-distance matrix descriptors: optimal abstract 3D space granularity for predicting estrogen binding. J Chem Inf Model (2012) 0.81
Partial least square and k-nearest neighbor algorithms for improved 3D quantitative spectral data-activity relationship consensus modeling of acute toxicity. Environ Toxicol Chem (2014) 0.81
Single valproic acid treatment inhibits glycogen and RNA ribose turnover while disrupting glucose-derived cholesterol synthesis in liver as revealed by the [U-C(6)]-d-glucose tracer in mice. Metabolomics (2009) 0.80
Evaluations of the trans-sulfuration pathway in multiple liver toxicity studies. Toxicol Appl Pharmacol (2008) 0.79
Genetic associations with micronutrient levels identified in immune and gastrointestinal networks. Genes Nutr (2014) 0.79
Whole-molecule calculation of log p based on molar volume, hydrogen bonds, and simulated 13C NMR spectra. J Chem Inf Model (2005) 0.78
Metabolomics evaluation of hydroxyproline as a potential marker of melamine and cyanuric acid nephrotoxicity in male and female Fischer F344 rats. Food Chem Toxicol (2012) 0.78
Metabolomics techniques in nanotoxicology studies. Methods Mol Biol (2012) 0.77
Evaluating effects of penicillin treatment on the metabolome of rats. J Chromatogr B Analyt Technol Biomed Life Sci (2013) 0.77
Improving proton MR spectroscopy of brain tissue for noninvasive diagnostics. J Magn Reson Imaging (2010) 0.76
Modeling and assaying dioxin-like biological effects for both dioxin-like and certain non-dioxin-like compounds. Toxicol Sci (2007) 0.76
The role of metabolic biomarkers in drug toxicity studies. Toxicol Mech Methods (2008) 0.76
Predicting toxic equivalence factors from 13C nuclear magnetic resonance spectra for dioxins, furans, and polychlorinated biphenyls using linear and nonlinear pattern recognition methods. Environ Toxicol Chem (2004) 0.75
The use of carbon thirteen nuclear magnetic resonance spectra to predict dioxin and furan binding affinities to the aryl hydrocarbon receptor. Environ Toxicol Chem (2003) 0.75
The liver toxicity biomarker study phase I: markers for the effects of tolcapone or entacapone. Toxicol Pathol (2012) 0.75