PubRank

Jonathan D Smith

Author PubWeight™ 126.73‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. Nature 2011 13.53
2 Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis. Nat Med 2013 9.44
3 ApoE promotes the proteolytic degradation of Abeta. Neuron 2008 4.75
4 Common variants in KCNN3 are associated with lone atrial fibrillation. Nat Genet 2010 3.97
5 Genome-wide association study of PR interval. Nat Genet 2010 3.73
6 Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet 2012 3.71
7 Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease. J Clin Invest 2004 3.63
8 Paradoxical association of enhanced cholesterol efflux with increased incident cardiovascular risks. Arterioscler Thromb Vasc Biol 2013 3.07
9 The refined structure of nascent HDL reveals a key functional domain for particle maturation and dysfunction. Nat Struct Mol Biol 2007 2.47
10 Independent susceptibility markers for atrial fibrillation on chromosome 4q25. Circulation 2010 1.90
11 Localization of nitration and chlorination sites on apolipoprotein A-I catalyzed by myeloperoxidase in human atheroma and associated oxidative impairment in ABCA1-dependent cholesterol efflux from macrophages. J Biol Chem 2004 1.80
12 High-density lipoprotein function, dysfunction, and reverse cholesterol transport. Arterioscler Thromb Vasc Biol 2012 1.70
13 Effects of native and myeloperoxidase-modified apolipoprotein a-I on reverse cholesterol transport and atherosclerosis in mice. Arterioscler Thromb Vasc Biol 2014 1.66
14 A phenotype-sensitizing Apoe-deficient genetic background reveals novel atherosclerosis predisposition loci in the mouse. Genetics 2002 1.61
15 Modification of high density lipoprotein by myeloperoxidase generates a pro-inflammatory particle. J Biol Chem 2009 1.51
16 Identification of apolipoprotein D as a cardioprotective gene using a mouse model of lethal atherosclerotic coronary artery disease. Proc Natl Acad Sci U S A 2013 1.48
17 Supervised principal component analysis for gene set enrichment of microarray data with continuous or survival outcomes. Bioinformatics 2008 1.45
18 Quantitative assay for mouse atherosclerosis in the aortic root. Methods Mol Med 2006 1.38
19 A simple and sensitive enzymatic method for cholesterol quantification in macrophages and foam cells. J Lipid Res 2010 1.34
20 Tyrosine modification is not required for myeloperoxidase-induced loss of apolipoprotein A-I functional activities. J Biol Chem 2005 1.33
21 Sex specific gene regulation and expression QTLs in mouse macrophages from a strain intercross. PLoS One 2008 1.24
22 Apolipoprotein E promotes β-amyloid trafficking and degradation by modulating microglial cholesterol levels. J Biol Chem 2011 1.23
23 Apolipoprotein A-I tryptophan substitution leads to resistance to myeloperoxidase-mediated loss of function. Arterioscler Thromb Vasc Biol 2008 1.23
24 The cardioprotective protein apolipoprotein A1 promotes potent anti-tumorigenic effects. J Biol Chem 2013 1.22
25 Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex. J Clin Invest 2013 1.21
26 Thrombospondin-4 regulates vascular inflammation and atherogenesis. Circ Res 2010 1.19
27 Changes in whole blood gene expression in obese subjects with type 2 diabetes following bariatric surgery: a pilot study. PLoS One 2011 1.17
28 Direct electrochemical evaluation of plasma membrane cholesterol in live mammalian cells. J Am Chem Soc 2007 1.14
29 Sphingosine-1-phosphate receptor-2 function in myeloid cells regulates vascular inflammation and atherosclerosis. Arterioscler Thromb Vasc Biol 2010 1.14
30 Whole genome expression differences in human left and right atria ascertained by RNA sequencing. Circ Cardiovasc Genet 2012 1.12
31 Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation. Circulation 2014 1.11
32 Dysregulation of cholesterol homeostasis in human prostate cancer through loss of ABCA1. Cancer Res 2012 1.10
33 A common connexin-40 gene promoter variant affects connexin-40 expression in human atria and is associated with atrial fibrillation. Circ Arrhythm Electrophysiol 2010 1.09
34 Phospholipase C beta3 deficiency leads to macrophage hypersensitivity to apoptotic induction and reduction of atherosclerosis in mice. J Clin Invest 2008 1.09
35 Akt3 deficiency in macrophages promotes foam cell formation and atherosclerosis in mice. Cell Metab 2012 1.07
36 Safe and effective method for chronic 17beta-estradiol administration to mice. Contemp Top Lab Anim Sci 2003 1.05
37 High-density lipoprotein and atherosclerosis regression: evidence from preclinical and clinical studies. Circ Res 2014 1.04
38 Zymosan-mediated inflammation impairs in vivo reverse cholesterol transport. J Lipid Res 2011 1.04
39 Homocysteine inhibits neoangiogenesis in mice through blockade of annexin A2-dependent fibrinolysis. J Clin Invest 2009 1.04
40 Apolipoprotein A-I lysine modification: effects on helical content, lipid binding and cholesterol acceptor activity. Biochim Biophys Acta 2006 1.03
41 Red blood cells play a role in reverse cholesterol transport. Arterioscler Thromb Vasc Biol 2012 1.03
42 The critical role of IL-1 receptor-associated kinase 4-mediated NF-κB activation in modified low-density lipoprotein-induced inflammatory gene expression and atherosclerosis. J Immunol 2011 1.02
43 17Alpha-estradiol and 17beta-estradiol treatments are effective in lowering cerebral amyloid-beta levels in AbetaPPSWE transgenic mice. J Alzheimers Dis 2002 1.02
44 Protection of extraribosomal RPL13a by GAPDH and dysregulation by S-nitrosylation. Mol Cell 2012 1.01
45 Cyclosporin A traps ABCA1 at the plasma membrane and inhibits ABCA1-mediated lipid efflux to apolipoprotein A-I. Arterioscler Thromb Vasc Biol 2004 0.98
46 MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases. J Exp Med 2014 0.98
47 Site-specific nitration of apolipoprotein A-I at tyrosine 166 is both abundant within human atherosclerotic plaque and dysfunctional. J Biol Chem 2014 0.98
48 Deficiency of LRP8 in mice is associated with altered platelet function and prolonged time for in vivo thrombosis. Thromb Res 2008 0.98
49 Identification of the cAMP-responsive enhancer of the murine ABCA1 gene: requirement for CREB1 and STAT3/4 elements. Arterioscler Thromb Vasc Biol 2005 0.96
50 Function and distribution of apolipoprotein A1 in the artery wall are markedly distinct from those in plasma. Circulation 2013 0.96
51 Aging, gender and APOE isotype modulate metabolism of Alzheimer's Abeta peptides and F-isoprostanes in the absence of detectable amyloid deposits. J Neurochem 2004 0.95
52 Lack of mitogen-activated protein kinase phosphatase-1 protects ApoE-null mice against atherosclerosis. Circ Res 2010 0.95
53 Identification of a novel enhancer of brain expression near the apoE gene cluster by comparative genomics. Biochim Biophys Acta 2004 0.93
54 Decreased atherosclerosis in mice deficient in tumor necrosis factor-alpha receptor-II (p75). Arterioscler Thromb Vasc Biol 2007 0.93
55 Diabetic HDL is dysfunctional in stimulating endothelial cell migration and proliferation due to down regulation of SR-BI expression. PLoS One 2012 0.93
56 2H2O-based high-density lipoprotein turnover method for the assessment of dynamic high-density lipoprotein function in mice. Arterioscler Thromb Vasc Biol 2013 0.89
57 Reevaluation of the role of the multidrug-resistant P-glycoprotein in cellular cholesterol homeostasis. J Lipid Res 2005 0.88
58 Large disk intermediate precedes formation of apolipoprotein A-I-dimyristoylphosphatidylcholine small disks. Biochemistry 2007 0.87
59 Genetic-genomic replication to identify candidate mouse atherosclerosis modifier genes. J Am Heart Assoc 2013 0.87
60 The low-resolution structure of nHDL reconstituted with DMPC with and without cholesterol reveals a mechanism for particle expansion. J Lipid Res 2013 0.86
61 ABCA1 and nascent HDL biogenesis. Biofactors 2014 0.86
62 Weighted gene coexpression network analysis of human left atrial tissue identifies gene modules associated with atrial fibrillation. Circ Cardiovasc Genet 2013 0.86
63 ABCA1 mediates unfolding of apolipoprotein AI N terminus on the cell surface before lipidation and release of nascent high-density lipoprotein. Arterioscler Thromb Vasc Biol 2013 0.86
64 Dietary methionine effects on plasma homocysteine and HDL metabolism in mice. J Nutr Biochem 2007 0.86
65 Comparing variation in Medicare and private insurance spending in Texas. Am J Manag Care 2011 0.85
66 Transcriptome analysis of genes regulated by cholesterol loading in two strains of mouse macrophages associates lysosome pathway and ER stress response with atherosclerosis susceptibility. PLoS One 2013 0.85
67 Moderately decreased cholesterol absorption rates are associated with a large atheroprotective effect. Arterioscler Thromb Vasc Biol 2009 0.84
68 A novel folding intermediate state for apolipoprotein A-I: role of the amino and carboxy termini. Biophys J 2005 0.84
69 Human cerebrospinal fluid apolipoprotein E isoforms are apparently inefficient at complexing with synthetic Alzheimer's amyloid-[beta] peptide (A[beta] 1-40 ) in vitro. Mol Med 2002 0.83
70 Ribosomal protein L13a deficiency in macrophages promotes atherosclerosis by limiting translation control-dependent retardation of inflammation. Arterioscler Thromb Vasc Biol 2014 0.82
71 Lack of a significant role of P-Rex1, a major regulator of macrophage Rac1 activation and chemotaxis, in atherogenesis. Prostaglandins Other Lipid Mediat 2008 0.81
72 Physiological difference in autophagic flux in macrophages from 2 mouse strains regulates cholesterol ester metabolism. Arterioscler Thromb Vasc Biol 2013 0.81
73 Genome-wide studies of gene expression relevant to coronary artery disease. Curr Opin Cardiol 2012 0.81
74 Sphingomyelin depletion impairs anionic phospholipid inward translocation and induces cholesterol efflux. J Biol Chem 2013 0.80
75 Low prevalence of connexin-40 gene variants in atrial tissues and blood from atrial fibrillation subjects. BMC Med Genet 2012 0.80
76 Deficiency of clusterin inhibits neointimal hyperplasia after vascular injury. J Atheroscler Thromb 2009 0.79
77 Similar promotion of Abeta1-42 fibrillogenesis by native apolipoprotein E epsilon3 and epsilon4 isoforms. J Neuroinflammation 2004 0.79
78 Insight into ABCG1-mediated cholesterol efflux. Arterioscler Thromb Vasc Biol 2006 0.79
79 A novel compound inhibits reconstituted high-density lipoprotein assembly and blocks nascent high-density lipoprotein biogenesis downstream of apolipoprotein AI binding to ATP-binding cassette transporter A1-expressing cells. Arterioscler Thromb Vasc Biol 2011 0.79
80 An antiatherosclerotic signaling cascade involving intestinal microbiota, microRNA-10b, and ABCA1/ABCG1-mediated reverse cholesterol transport. Circ Res 2012 0.78
81 Ovariectomy of young mutant amyloid precursor protein transgenic mice leads to increased mortality. J Mol Neurosci 2002 0.77
82 Expression of the carrier protein apolipoprotein D in the mouse inner ear. Hear Res 2005 0.77
83 A₁ adenosine receptor deficiency or inhibition reduces atherosclerotic lesions in apolipoprotein E deficient mice. Cardiovasc Res 2014 0.77
84 Confirmation of the microsomal triglyceride transfer protein genetic effect on lipids in young African American men from the CARDIA study. Arterioscler Thromb Vasc Biol 2003 0.76
85 Free-cholesterol-mediated autophagy of ORMDL1 stimulates sphingomyelin biosynthesis. Autophagy 2015 0.76
86 The murine macrophage apoB-48 receptor gene (Apob-48r): homology to the human receptor. J Lipid Res 2002 0.76
87 Combining genome-wide data from humans and animal models of dyslipidemia and atherosclerosis. Curr Opin Lipidol 2011 0.75
88 Proteome Dynamics Reveals Pro-Inflammatory Remodeling of Plasma Proteome in a Mouse Model of NAFLD. J Proteome Res 2016 0.75
89 Drug library screen to identify compounds that decrease secreted Abeta from a human cell line. Curr Alzheimer Res 2005 0.75
90 Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Nat Genet 2017 0.75
91 Synthesis and biological evaluation of analogues of a novel inhibitor of beta-amyloid secretion. J Med Chem 2010 0.75
92 Fifteen Genetic Loci Associated With the Electrocardiographic P Wave. Circ Cardiovasc Genet 2017 0.75