G Sesti

Author PubWeight™ 51.14‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Insulin sensitivity, insulin release and glucagon-like peptide-1 levels in persons with impaired fasting glucose and/or impaired glucose tolerance in the EUGENE2 study. Diabetologia 2007 2.16
2 High glucose causes apoptosis in cultured human pancreatic islets of Langerhans: a potential role for regulation of specific Bcl family genes toward an apoptotic cell death program. Diabetes 2001 2.02
3 Elevated one-hour post-load plasma glucose levels identifies subjects with normal glucose tolerance but early carotid atherosclerosis. Atherosclerosis 2009 1.94
4 Relation between serum uric acid and carotid intima-media thickness in healthy postmenopausal women. Intern Emerg Med 2007 1.72
5 The common SLC30A8 Arg325Trp variant is associated with reduced first-phase insulin release in 846 non-diabetic offspring of type 2 diabetes patients--the EUGENE2 study. Diabetologia 2008 1.53
6 The Gly972-->Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic beta cells. J Clin Invest 1999 1.26
7 Insulin receptor substrate 1 mediates the stimulatory effect of insulin on GLUT4 translocation in transfected rat adipose cells. J Biol Chem 1994 1.26
8 C-reactive protein induces phosphorylation of insulin receptor substrate-1 on Ser307 and Ser 612 in L6 myocytes, thereby impairing the insulin signalling pathway that promotes glucose transport. Diabetologia 2007 1.18
9 Insulin receptor substrate (IRS) transduction system: distinct and overlapping signaling potential. Diabetes Metab Res Rev 2001 1.17
10 Variant sequences of insulin receptor substrate-1 in patients with noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab 1994 1.14
11 The Gly-->Arg972 amino acid polymorphism in insulin receptor substrate-1 affects glucose metabolism in skeletal muscle cells. J Clin Endocrinol Metab 2000 1.06
12 An empirical index of insulin sensitivity from short IVGTT: validation against the minimal model and glucose clamp indices in patients with different clinical characteristics. Diabetologia 2009 1.04
13 Altered pattern of insulin receptor isotypes in skeletal muscle membranes of type 2 (non-insulin-dependent) diabetic subjects. Diabetologia 1993 1.03
14 Low plasma insulin-like growth factor-1 levels are associated with reduced insulin sensitivity and increased insulin secretion in nondiabetic subjects. Nutr Metab Cardiovasc Dis 2009 0.99
15 Distribution of insulin/insulin-like growth factor-I hybrid receptors in human tissues. Mol Cell Endocrinol 1997 0.98
16 IRS1 G972R polymorphism and type 2 diabetes: a paradigm for the difficult ascertainment of the contribution to disease susceptibility of 'low-frequency-low-risk' variants. Diabetologia 2009 0.96
17 The common Arg972 polymorphism in insulin receptor substrate-1 causes apoptosis of human pancreatic islets. FASEB J 2000 0.95
18 The PEA15 gene is overexpressed and related to insulin resistance in healthy first-degree relatives of patients with type 2 diabetes. Diabetologia 2006 0.93
19 Expression of insulin/IGF-I hybrid receptors is increased in skeletal muscle of patients with chronic primary hyperinsulinemia. Diabetes 1998 0.93
20 Increased abundance of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of obese subjects is correlated with in vivo insulin sensitivity. J Clin Endocrinol Metab 1998 0.92
21 Increased expression of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of noninsulin-dependent diabetes mellitus subjects. J Clin Invest 1996 0.92
22 Transgenic mice overexpressing human G972R IRS-1 show impaired insulin action and insulin secretion. J Cell Mol Med 2008 0.92
23 One-hour post-load plasma glucose levels are associated with elevated liver enzymes. Nutr Metab Cardiovasc Dis 2011 0.92
24 Increased abundance of insulin/IGF-I hybrid receptors in adipose tissue from NIDDM patients. Mol Cell Endocrinol 1997 0.92
25 Modulation of insulin secretion by diazepam binding inhibitor and its processing products. Neuropharmacology 1991 0.90
26 Increased levels of the Akt-specific phosphatase PH domain leucine-rich repeat protein phosphatase (PHLPP)-1 in obese participants are associated with insulin resistance. Diabetologia 2011 0.88
27 Expression of variant forms of insulin receptor substrate-1 identified in patients with noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab 1997 0.87
28 IL-18 gene polymorphism and metabolic syndrome. Nutr Metab Cardiovasc Dis 2009 0.87
29 Endothelial dysfunction and non-alcoholic liver steatosis in hypertensive patients. Nutr Metab Cardiovasc Dis 2010 0.86
30 TRIB3 R84 variant affects glucose homeostasis by altering the interplay between insulin sensitivity and secretion. Diabetologia 2010 0.85
31 Molecular and functional characterization of pituitary adenylate cyclase-activating polypeptide (PACAP-38)/vasoactive intestinal polypeptide receptors in pancreatic beta-cells and effects of PACAP-38 on components of the insulin secretory system. Endocrinology 1999 0.84
32 The effects of pregnancy steroids on adaptation of beta cells to pregnancy involve the pancreatic glucose sensor glucokinase. J Endocrinol 1997 0.84
33 Molecular and cellular characterization of the GABAA receptor in the rat pancreas. Mol Cell Endocrinol 1994 0.84
34 Comparison of A1C, fasting and 2-h post-load plasma glucose criteria to diagnose diabetes in Italian Caucasians. Nutr Metab Cardiovasc Dis 2011 0.83
35 Role of endogenous androgens on carotid atherosclerosis in non-obese postmenopausal women. Nutr Metab Cardiovasc Dis 2007 0.82
36 Effect of biotin on glucokinase activity, mRNA expression and insulin release in cultured beta-cells. Acta Diabetol 1996 0.81
37 GRB10 gene and type 2 diabetes in Whites. J Intern Med 2009 0.81
38 Glucose tolerance, insulin sensitivity and insulin release in European non-diabetic carriers of a polymorphism upstream of CDKN2A and CDKN2B. Diabetologia 2011 0.80
39 New insights into body composition assessment in obese women. Can J Physiol Pharmacol 1999 0.80
40 Evidence for glucose/hexosamine in vivo regulation of insulin/IGF-I hybrid receptor assembly. Diabetes 1999 0.79
41 Quantitative analysis of pancreatic glucokinase gene expression in cultured beta cells by competitive polymerase chain reaction. Mol Cell Endocrinol 1996 0.79
42 The sulfonylurea glimepiride regulates intracellular routing of the insulin-receptor complexes through their interaction with specific protein kinase C isoforms. Mol Pharmacol 2001 0.79
43 Effect of insulin on hydrogen peroxide production by human polymorphonuclear leukocytes. Studies with monoclonal anti-insulin receptor antibodies, and an agonist and an inhibitor of protein kinase C. Horm Res 1995 0.78
44 Beta-endorphin receptors on cultured and freshly isolated lymphocytes from normal subjects. Biochem Biophys Res Commun 1989 0.78
45 An extracellular domain of the insulin receptor beta-subunit with regulatory function on protein-tyrosine kinase. J Biol Chem 1989 0.77
46 DBI mRNA is expressed in endocrine pancreas and its post-translational product DBI(33-50) inhibits insulin release. Endocrine 1995 0.77
47 The SH2B1 obesity locus and abnormal glucose homeostasis: lack of evidence for association from a meta-analysis in individuals of European ancestry. Nutr Metab Cardiovasc Dis 2013 0.77
48 Direct modulation of insulin receptor protein tyrosine kinase by vanadate and anti-insulin receptor monoclonal antibodies. Biochem Biophys Res Commun 1988 0.77
49 Unfavorable inflammatory profile in adults at risk of type 2 diabetes identified by hemoglobin A1c levels according to the American Diabetes Association criteria. Acta Diabetol 2014 0.77
50 Increased expression of low-affinity insulin receptor isoform and insulin/insulin-like growth factor-I hybrid receptors in term placenta from insulin-resistant women with gestational hypertension. Diabetologia 1996 0.76
51 GLUT2 and glucokinase expression is coordinately regulated by sulfonylurea. Mol Cell Endocrinol 1999 0.76
52 Insulin receptor tyrosine-kinase activity is altered in both muscle and adipose tissue from non-obese normoglycaemic insulin-resistant subjects. Diabetologia 1995 0.76
53 Chronobiological approach to the treatment of essential hypertension: preliminary data. Int J Clin Pharmacol Ther Toxicol 1984 0.75
54 Antibodies directed to the insulin receptor. Clinical aspects and applications to the study of insulin action. J Endocrinol Invest 1990 0.75
55 The Search for NIDDM genes project: a European Community programme aimed to facilitate the identification of NIDDM genes. Diabetologia 1998 0.75
56 Neuronal increase in the trout (Salmo trutta fario) spinal cord during development. Cell Mol Biol 1984 0.75