Published in Ann N Y Acad Sci on November 01, 2007
Osteoblast precursors, but not mature osteoblasts, move into developing and fractured bones along with invading blood vessels. Dev Cell (2010) 4.99
BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway. Development (2008) 1.86
Regulation of osteogenesis-angiogenesis coupling by HIFs and VEGF. J Bone Miner Res (2009) 1.68
A mouse model of osteochondromagenesis from clonal inactivation of Ext1 in chondrocytes. Proc Natl Acad Sci U S A (2009) 1.47
Hypoxia, HIFs and bone development. Bone (2010) 1.29
Identification of a clonally expanding haematopoietic compartment in bone marrow. EMBO J (2012) 1.19
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Snail1 controls bone mass by regulating Runx2 and VDR expression during osteoblast differentiation. EMBO J (2009) 1.00
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ATF4 promotes bone angiogenesis by increasing VEGF expression and release in the bone environment. J Bone Miner Res (2013) 0.89
Loss-of-function of ACVR1 in osteoblasts increases bone mass and activates canonical Wnt signaling through suppression of Wnt inhibitors SOST and DKK1. Biochem Biophys Res Commun (2011) 0.88
Prospects for osteoprogenitor stem cells in fracture repair and osteoporosis. Curr Opin Organ Transplant (2010) 0.83
Intermittent PTH treatment can delay the transformation of mature osteoblasts into lining cells on the periosteal surfaces. J Bone Miner Metab (2015) 0.82
Ephrin B2/EphB4 mediates the actions of IGF-I signaling in regulating endochondral bone formation. J Bone Miner Res (2014) 0.82
Postnatal ablation of osteoblast Smad4 enhances proliferative responses to canonical Wnt signaling through interactions with β-catenin. J Cell Sci (2013) 0.81
Role of IGF-I signaling in muscle bone interactions. Bone (2015) 0.80
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Ras signaling regulates osteoprogenitor cell proliferation and bone formation. Cell Death Dis (2016) 0.75
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Bone loss in adult offspring induced by low-dose exposure to teratogens. J Bone Miner Metab (2011) 0.75
In vivo rescue of the hematopoietic niche by pluripotent stem cell complementation of defective osteoblast compartments. Stem Cells (2017) 0.75
Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia. Nature (2010) 5.43
Osteoblast precursors, but not mature osteoblasts, move into developing and fractured bones along with invading blood vessels. Dev Cell (2010) 4.99
Endogenous bone marrow MSCs are dynamic, fate-restricted participants in bone maintenance and regeneration. Cell Stem Cell (2012) 4.67
Therapeutic targeting of a stem cell niche. Nat Biotechnol (2007) 3.88
Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation. Nat Med (2008) 3.64
Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo. Cell Stem Cell (2008) 3.62
Dicer-dependent pathways regulate chondrocyte proliferation and differentiation. Proc Natl Acad Sci U S A (2008) 3.10
Genetic control of bone formation. Annu Rev Cell Dev Biol (2009) 3.06
Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton. Development (2004) 2.39
PTHrP and Indian hedgehog control differentiation of growth plate chondrocytes at multiple steps. Development (2002) 2.19
Osteoblastic regulation of B lymphopoiesis is mediated by Gs{alpha}-dependent signaling pathways. Proc Natl Acad Sci U S A (2008) 2.15
Loss of wnt/β-catenin signaling causes cell fate shift of preosteoblasts from osteoblasts to adipocytes. J Bone Miner Res (2012) 2.01
Hif-1alpha regulates differentiation of limb bud mesenchyme and joint development. J Cell Biol (2007) 1.95
Osteoblast-derived PTHrP is a potent endogenous bone anabolic agent that modifies the therapeutic efficacy of administered PTH 1-34. J Clin Invest (2005) 1.88
BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway. Development (2008) 1.86
Myelopoiesis is regulated by osteocytes through Gsα-dependent signaling. Blood (2012) 1.83
Indian hedgehog stimulates periarticular chondrocyte differentiation to regulate growth plate length independently of PTHrP. J Clin Invest (2005) 1.82
Intermittent parathyroid hormone administration converts quiescent lining cells to active osteoblasts. J Bone Miner Res (2012) 1.81
Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy. Development (2008) 1.79
Suppression of Wnt signaling by Dkk1 attenuates PTH-mediated stromal cell response and new bone formation. Cell Metab (2010) 1.62
Bradykinin decreases plasminogen activator inhibitor-1 expression and facilitates matrix degradation in the renal tubulointerstitium under angiotensin-converting enzyme blockade. J Am Soc Nephrol (2004) 1.61
HDAC5 controls MEF2C-driven sclerostin expression in osteocytes. J Bone Miner Res (2015) 1.60
Deletion of Vhlh in chondrocytes reduces cell proliferation and increases matrix deposition during growth plate development. Development (2004) 1.58
Effect of acute and long-term aerobic exercise on arterial stiffness in the elderly. Hypertens Res (2007) 1.55
Wnt inhibitors Dkk1 and Sost are downstream targets of BMP signaling through the type IA receptor (BMPRIA) in osteoblasts. J Bone Miner Res (2010) 1.54
Disruption of BMP signaling in osteoblasts through type IA receptor (BMPRIA) increases bone mass. J Bone Miner Res (2008) 1.54
Connective tissue growth factor expressed in tubular epithelium plays a pivotal role in renal fibrogenesis. J Am Soc Nephrol (2004) 1.53
Anabolic action of parathyroid hormone regulated by the β2-adrenergic receptor. Proc Natl Acad Sci U S A (2012) 1.50
PTH/PTHrP receptor delays chondrocyte hypertrophy via both Runx2-dependent and -independent pathways. Dev Biol (2006) 1.50
Targeted ablation of the PTH/PTHrP receptor in osteocytes impairs bone structure and homeostatic calcemic responses. J Endocrinol (2011) 1.50
Stimulatory G protein directly regulates hypertrophic differentiation of growth plate cartilage in vivo. Proc Natl Acad Sci U S A (2004) 1.46
ADAMTS-7, a direct target of PTHrP, adversely regulates endochondral bone growth by associating with and inactivating GEP growth factor. Mol Cell Biol (2009) 1.46
BMP signaling stimulates cellular differentiation at multiple steps during cartilage development. Proc Natl Acad Sci U S A (2005) 1.44
Chondrocyte-specific knockout of the G protein G(s)alpha leads to epiphyseal and growth plate abnormalities and ectopic chondrocyte formation. J Bone Miner Res (2004) 1.37
T lymphocytes amplify the anabolic activity of parathyroid hormone through Wnt10b signaling. Cell Metab (2009) 1.32
Haematopoietic stem cells depend on Galpha(s)-mediated signalling to engraft bone marrow. Nature (2009) 1.27
In vivo evidence that BMP signaling is necessary for apoptosis in the mouse limb. Dev Biol (2002) 1.27
The PTH/PTHrP receptor can delay chondrocyte hypertrophy in vivo without activating phospholipase C. Dev Cell (2002) 1.24
Chondrocyte-specific microRNA-140 regulates endochondral bone development and targets Dnpep to modulate bone morphogenetic protein signaling. Mol Cell Biol (2011) 1.24
Absence of transcription factor c-maf causes abnormal terminal differentiation of hypertrophic chondrocytes during endochondral bone development. Dev Biol (2003) 1.23
p107 and p130 Coordinately regulate proliferation, Cbfa1 expression, and hypertrophic differentiation during endochondral bone development. Dev Biol (2002) 1.22
Reproducibility of results in preclinical studies: a perspective from the bone field. J Bone Miner Res (2014) 1.20
Nkx3.2/Bapx1 acts as a negative regulator of chondrocyte maturation. Development (2006) 1.16
Parathyroid hormone/parathyroid hormone-related protein receptor signaling is required for maintenance of the growth plate in postnatal life. Proc Natl Acad Sci U S A (2010) 1.14
Role of the osteoblast lineage in the bone marrow hematopoietic niches. J Bone Miner Res (2009) 1.13
Radial augmentation index: a useful and easily obtainable parameter for vascular aging. Am J Hypertens (2005) 1.12
Arrested pulmonary alveolar cytodifferentiation and defective surfactant synthesis in mice missing the gene for parathyroid hormone-related protein. Dev Dyn (2004) 1.11
Gsα enhances commitment of mesenchymal progenitors to the osteoblast lineage but restrains osteoblast differentiation in mice. J Clin Invest (2011) 1.08
Gamma knife stereotactic radiosurgery for atypical and malignant meningiomas. Acta Neurochir Suppl (2013) 1.03
A-raf and B-raf are dispensable for normal endochondral bone development, and parathyroid hormone-related peptide suppresses extracellular signal-regulated kinase activation in hypertrophic chondrocytes. Mol Cell Biol (2007) 1.03
Disruption of PTH receptor 1 in T cells protects against PTH-induced bone loss. PLoS One (2010) 1.03
The cyclin-dependent kinase inhibitor p57(Kip2) mediates proliferative actions of PTHrP in chondrocytes. J Clin Invest (2004) 1.00
Adenomatous polyposis coli-mediated control of beta-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursors. BMC Dev Biol (2009) 0.99
let-7 and miR-140 microRNAs coordinately regulate skeletal development. Proc Natl Acad Sci U S A (2013) 0.98
NPT2a--the key to phosphate homeostasis. N Engl J Med (2002) 0.97
Histopathological and ultrastructural features of Koi herpesvirus (KHV)-infected carp Cyprinus carpio, and the morphology and morphogenesis of KHV. Dis Aquat Organ (2008) 0.94
In vivo and in vitro effects of a novel anti-Dkk1 neutralizing antibody in multiple myeloma. Bone (2013) 0.94
Phospholipase C signaling via the parathyroid hormone (PTH)/PTH-related peptide receptor is essential for normal bone responses to PTH. Endocrinology (2010) 0.94
Long-term outcomes in patients with vestibular schwannomas treated using gamma knife surgery: 10-year follow up. J Neurosurg (2005) 0.92
MicroRNAs involved in bone formation. Cell Mol Life Sci (2014) 0.92
Sox9 is upstream of microRNA-140 in cartilage. Appl Biochem Biotechnol (2011) 0.92
Gp130-mediated signaling is necessary for normal osteoblastic function in vivo and in vitro. Endocrinology (2003) 0.91
Stereotactic radiosurgery for metastatic tumors in the pituitary gland and the cavernous sinus. J Neurosurg (2006) 0.90
MicroRNAs in cartilage development, homeostasis, and disease. Curr Osteoporos Rep (2014) 0.89
Reduced expression of the PTH/PTHrP receptor during development of the mammary gland influences the function of the nipple during lactation. Dev Dyn (2005) 0.89
Midgestational lethality in mice lacking the parathyroid hormone (PTH)/PTH-related peptide receptor is associated with abrupt cardiomyocyte death. Endocrinology (2003) 0.89
Stereotactic radiotherapy using Novalis for craniopharyngioma adjacent to optic pathways. J Neurooncol (2010) 0.88
Effect of demecolcine and nocodazole on the efficiency of chemically assisted removal of chromosomes and the developmental potential of nuclear transferred porcine oocytes. Cloning Stem Cells (2003) 0.88
Complete anterior knee dislocation 16 years after cruciate-retaining total knee arthroplasty. Orthopedics (2012) 0.87
Activation of a non-cAMP/PKA signaling pathway downstream of the PTH/PTHrP receptor is essential for a sustained hypophosphatemic response to PTH infusion in male mice. Endocrinology (2013) 0.87
Angiotensin II type 1 receptor blockade attenuates renal fibrogenesis in an immune-mediated nephritic kidney through counter-activation of angiotensin II type 2 receptor. Biochem Biophys Res Commun (2004) 0.87
Selective depletion of fibroblasts preserves morphology and the functional integrity of peritoneum in transgenic mice with peritoneal fibrosing syndrome. Kidney Int (2003) 0.86
Constitutively active parathyroid hormone receptor signaling in cells in osteoblastic lineage suppresses mechanical unloading-induced bone resorption. J Biol Chem (2007) 0.86
Osteopontin negatively regulates parathyroid hormone receptor signaling in osteoblasts. J Biol Chem (2008) 0.86
The utility of formalin-fixed and paraffin-embedded tissue blocks for quantitative analysis of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase mRNA expressed by colorectal cancer cells. Acta Histochem Cytochem (2007) 0.86
Trigeminal neuralgia caused by nerve compression by dilated superior cerebellar artery associated with cerebellar arteriovenous malformation: case report. Neurol Med Chir (Tokyo) (2013) 0.86
Assessment of spatial uncertainties in the radiotherapy process with the Novalis system. Int J Radiat Oncol Biol Phys (2009) 0.85
Stereotactic radiotherapy using Novalis for skull base metastases developing with cranial nerve symptoms. J Neurooncol (2010) 0.85
Gamma knife radiosurgery of brain metastasis from malignant pleural mesothelioma--report of three cases with autopsy study in a case. Nagoya J Med Sci (2014) 0.84
Hypofractionated stereotactic body radiotherapy for primary and metastatic liver tumors using the novalis image-guided system: preliminary results regarding efficacy and toxicity. Technol Cancer Res Treat (2010) 0.84
Stereotactic radiosurgery for pineal and related tumors. Prog Neurol Surg (2009) 0.84
Isolated cerebral varix developing sudden deterioration of neurological status because of thrombosis: a case report. Surg Neurol (2004) 0.84
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Tubular expression of connective tissue growth factor correlates with interstitial fibrosis in type 2 diabetic nephropathy. Nephrol Dial Transplant (2005) 0.83
Overview of skeletal development. Methods Mol Biol (2014) 0.83