Timothy J Brennan

Author PubWeight™ 59.77‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Immediate early genes after pulsed radiofrequency treatment: neurobiology in need of clinical trials. Anesthesiology 2005 2.73
2 A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat. Proc Natl Acad Sci U S A 2002 2.24
3 2007 in review: a dozen steps forward in Anesthesiology. Anesthesiology 2008 1.38
4 The ion channel ASIC1 contributes to visceral but not cutaneous mechanoreceptor function. Gastroenterology 2004 1.36
5 Characterization of Adelta- and C-fibers innervating the plantar rat hindpaw one day after an incision. J Neurophysiol 2002 1.32
6 Changes in tissue pH and temperature after incision indicate acidosis may contribute to postoperative pain. Anesthesiology 2004 1.24
7 Comparison of skin incision vs. skin plus deep tissue incision on ongoing pain and spontaneous activity in dorsal horn neurons. Pain 2009 1.24
8 Guarding pain and spontaneous activity of nociceptors after skin versus skin plus deep tissue incision. Anesthesiology 2010 1.18
9 Increased nerve growth factor after rat plantar incision contributes to guarding behavior and heat hyperalgesia. Pain 2005 1.17
10 Opioids: more to learn, improvements to be made. Anesthesiology 2003 1.13
11 Spontaneous discharge and increased heat sensitivity of rat C-fiber nociceptors are present in vitro after plantar incision. Pain 2004 1.12
12 Effect of blockade of nerve growth factor and tumor necrosis factor on pain behaviors after plantar incision. J Pain 2004 1.08
13 Spinal administration of MK-801 and NBQX demonstrates NMDA-independent dorsal horn sensitization in incisional pain. Pain 2005 1.07
14 Effect of AMG0347, a transient receptor potential type V1 receptor antagonist, and morphine on pain behavior after plantar incision. Anesthesiology 2008 1.07
15 Lactate concentrations in incisions indicate ischemic-like conditions may contribute to postoperative pain. J Pain 2006 1.06
16 Nerve growth factor expression after plantar incision in the rat. Anesthesiology 2007 1.05
17 Spinal glutamate receptor antagonists differentiate primary and secondary mechanical hyperalgesia caused by incision. Pain 2003 1.04
18 Acute effect of an incision on mechanosensitive afferents in the plantar rat hindpaw. J Neurophysiol 2002 1.03
19 Postoperative pain--clinical implications of basic research. Best Pract Res Clin Anaesthesiol 2007 1.02
20 Simultaneous disruption of mouse ASIC1a, ASIC2 and ASIC3 genes enhances cutaneous mechanosensitivity. PLoS One 2012 1.02
21 Strain and sex influence on pain sensitivity after plantar incision in the mouse. Anesthesiology 2006 1.01
22 Separate groups of dorsal horn neurons transmit spontaneous activity and mechanosensitivity one day after plantar incision. Eur J Pain 2008 1.00
23 Expression profile of nerve growth factor after muscle incision in the rat. Anesthesiology 2009 0.98
24 Persistent secondary hyperalgesia after gastrocnemius incision in the rat. Eur J Pain 2002 0.96
25 Excitatory amino acid release in the spinal cord caused by plantar incision in the rat. Pain 2002 0.96
26 Differential effect of capsaicin treatment on pain-related behaviors after plantar incision. J Pain 2009 0.96
27 Effect of plantar local anesthetic injection on dorsal horn neuron activity and pain behaviors caused by incision. Pain 2002 0.96
28 Sensitization of primary afferents to mechanical and heat stimuli after incision in a novel in vitro mouse glabrous skin-nerve preparation. Pain 2008 0.95
29 Effect of capsaicin treatment on nociceptors in rat glabrous skin one day after plantar incision. Pain 2009 0.92
30 The effect of the AMPA/kainate receptor antagonist LY293558 in a rat model of postoperative pain. J Pain 2006 0.92
31 Thoracic epidural analgesia and acute pain management. Anesthesiology 2011 0.90
32 Trpv1 mediates spontaneous firing and heat sensitization of cutaneous primary afferents after plantar incision. Pain 2008 0.90
33 Prevalence and risk factors predisposing to coagulopathy in patients receiving epidural analgesia for hepatic surgery. Reg Anesth Pain Med 2009 0.90
34 Nociceptive sensitization by complement C5a and C3a in mouse. Pain 2009 0.89
35 Increased local concentration of complement C5a contributes to incisional pain in mice. J Neuroinflammation 2011 0.89
36 Wound hypoxia in deep tissue after incision in rats. Wound Repair Regen 2013 0.89
37 Increased sensitivity of group III and group IV afferents from incised muscle in vitro. Pain 2010 0.89
38 Hind paw incision in the rat produces long-lasting colon hypersensitivity. J Pain 2007 0.88
39 Chemosensitivity and mechanosensitivity of nociceptors from incised rat hindpaw skin. Anesthesiology 2009 0.88
40 Ketoprofen produces modality-specific inhibition of pain behaviors in rats after plantar incision. Anesth Analg 2009 0.87
41 Preventive analgesia to reduce wound hyperalgesia and persistent postsurgical pain: not an easy path. Anesthesiology 2005 0.86
42 Gene expression in skin, muscle, and dorsal root ganglion after plantar incision in the rat. Anesthesiology 2012 0.86
43 Frontiers in translational research: the etiology of incisional and postoperative pain. Anesthesiology 2002 0.86
44 Pain assessment, sedation, and analgesic administration in the intensive care unit. Anesthesiology 2009 0.85
45 Role of the rostral medial medulla in the development of primary and secondary hyperalgesia after incision in the rat. Anesthesiology 2002 0.84
46 Mechanisms for pain caused by incisions. Reg Anesth Pain Med 2002 0.81
47 Epidural tezampanel, an AMPA/kainate receptor antagonist, produces postoperative analgesia in rats. Anesth Analg 2007 0.81
48 Neuropeptide Y is analgesic in rats after plantar incision. Eur J Pharmacol 2012 0.81
49 Transesophageal echocardiography: a novel technique for guidance and placement of an epidural catheter in infants. Anesthesiology 2013 0.80
50 Thermoregulatory behavior is disrupted in rats with lesions of the anteroventral third ventricular area (AV3V). Physiol Behav 2006 0.79
51 The pathophysiology of acute pain: animal models. Curr Opin Anaesthesiol 2011 0.79
52 A Comparison of 2 Ultrasound-Guided Approaches to the Saphenous Nerve Block: Adductor Canal Versus Distal Transsartorial: A Prospective, Randomized, Blinded, Noninferiority Trial. Reg Anesth Pain Med 2015 0.78
53 A new device concept for directly modulating spinal cord pathways: initial in vivo experimental results. Physiol Meas 2012 0.78
54 Incisional sensitivity and pain measurements: dissecting mechanisms for postoperative pain. Anesthesiology 2005 0.78
55 Bradykinin antagonists have no analgesic effect on incisional pain. Anesth Analg 2004 0.77
56 Effect of intrathecal non-NMDA EAA receptor antagonist LY293558 in rats: a new class of drugs for spinal anesthesia. Anesthesiology 2002 0.77
57 Effect of deep tissue incision on pH responses of afferent fibers and dorsal root ganglia innervating muscle. Anesthesiology 2013 0.76
58 Evaluation of leukemia inhibitory factor (LIF) in a rat model of postoperative pain. J Pain 2011 0.75
59 Perioperative pain management in the opioid-tolerant individual. J Pain 2008 0.75
60 A Prospective Study of Chronic Pain after Thoracic Surgery. Anesthesiology 2017 0.75
61 Conditioned place preference and spontaneous dorsal horn neuron activity in chronic constriction injury model in rats. Pain 2015 0.75
62 In Reply. Anesthesiology 2018 0.75
63 2008 in review: advancing medicine in anesthesiology. Anesthesiology 2008 0.75
64 H2O2 Induces Muscle Nociception via Transient Receptor Potential Ankyrin 1 Receptors. Anesthesiology 2017 0.75
65 Continuous cervical paravertebral catheter knot. J Clin Anesth 2010 0.75
66 Anesthesiology and the press. Anesthesiology 2007 0.75
67 Successful conservative management of an intrathecal catheter-associated inflammatory mass. Spine J 2013 0.75