| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Autologous bone marrow-derived stem-cell transfer in patients with ST-segment elevation myocardial infarction: double-blind, randomised controlled trial.
|
Lancet
|
2006
|
7.33
|
|
2
|
18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment: a phase 2 trial.
|
Ann Neurol
|
2010
|
3.49
|
|
3
|
Optimized in vivo detection of dopamine release using 18F-fallypride PET.
|
J Nucl Med
|
2012
|
2.18
|
|
4
|
The acyclic CB1R inverse agonist taranabant mediates weight loss by increasing energy expenditure and decreasing caloric intake.
|
Cell Metab
|
2008
|
1.94
|
|
5
|
[18F]MK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor.
|
Proc Natl Acad Sci U S A
|
2007
|
1.73
|
|
6
|
Phase 1 study of the Pittsburgh compound B derivative 18F-flutemetamol in healthy volunteers and patients with probable Alzheimer disease.
|
J Nucl Med
|
2009
|
1.70
|
|
7
|
Regional brain activation during proximal stomach distention in humans: A positron emission tomography study.
|
Gastroenterology
|
2005
|
1.58
|
|
8
|
Highly efficient multicistronic lentiviral vectors with peptide 2A sequences.
|
Hum Gene Ther
|
2009
|
1.54
|
|
9
|
Increased ventral striatal CB1 receptor binding is related to negative symptoms in drug-free patients with schizophrenia.
|
Neuroimage
|
2013
|
1.48
|
|
10
|
Brain type 1 cannabinoid receptor availability in patients with anorexia and bulimia nervosa.
|
Biol Psychiatry
|
2011
|
1.48
|
|
11
|
Prognostic value of pretransplantation positron emission tomography using fluorine 18-fluorodeoxyglucose in patients with aggressive lymphoma treated with high-dose chemotherapy and stem cell transplantation.
|
Blood
|
2003
|
1.40
|
|
12
|
[(18)F]FDG PET monitoring of tumour response to chemotherapy: does [(18)F]FDG uptake correlate with the viable tumour cell fraction?
|
Eur J Nucl Med Mol Imaging
|
2003
|
1.35
|
|
13
|
Direct comparison of 18F-FDG and 11C-methionine PET in suspected recurrence of glioma: sensitivity, inter-observer variability and prognostic value.
|
Eur J Nucl Med Mol Imaging
|
2004
|
1.30
|
|
14
|
Characterization of pinhole SPECT acquisition geometry.
|
IEEE Trans Med Imaging
|
2003
|
1.27
|
|
15
|
A dual-targeting anticancer approach: soil and seed principle.
|
Radiology
|
2011
|
1.21
|
|
16
|
Gender-dependent increases with healthy aging of the human cerebral cannabinoid-type 1 receptor binding using [(18)F]MK-9470 PET.
|
Neuroimage
|
2007
|
1.12
|
|
17
|
Noninvasive monitoring of long-term lentiviral vector-mediated gene expression in rodent brain with bioluminescence imaging.
|
Mol Ther
|
2006
|
1.11
|
|
18
|
Construction and evaluation of multitracer small-animal PET probabilistic atlases for voxel-based functional mapping of the rat brain.
|
J Nucl Med
|
2006
|
1.10
|
|
19
|
Non-invasive detection and quantification of acute myocardial infarction in rabbits using mono-[123I]iodohypericin microSPECT.
|
Eur Heart J
|
2007
|
1.07
|
|
20
|
Abeta amyloid deposition in the language system and how the brain responds.
|
Brain
|
2007
|
1.05
|
|
21
|
Regional cerebral blood flow during gastric balloon distention in functional dyspepsia.
|
Gastroenterology
|
2007
|
1.02
|
|
22
|
Measuring extrastriatal dopamine release during a reward learning task.
|
Hum Brain Mapp
|
2011
|
1.01
|
|
23
|
Necrosis avidity of (99m)Tc(CO)3-labeled pamoic acid derivatives: synthesis and preliminary biological evaluation in animal models of necrosis.
|
Bioconjug Chem
|
2007
|
1.01
|
|
24
|
Optimization of geometrical calibration in pinhole SPECT.
|
IEEE Trans Med Imaging
|
2005
|
1.01
|
|
25
|
Relationship of type 1 cannabinoid receptor availability in the human brain to novelty-seeking temperament.
|
Arch Gen Psychiatry
|
2009
|
1.01
|
|
26
|
Image-derived input function for [11C]flumazenil kinetic analysis in human brain.
|
Mol Imaging Biol
|
2003
|
0.99
|
|
27
|
Abnormal regional brain activity during rest and (anticipated) gastric distension in functional dyspepsia and the role of anxiety: a H(2)(15)O-PET study.
|
Am J Gastroenterol
|
2010
|
0.96
|
|
28
|
Necrosis avid contrast agents: functional similarity versus structural diversity.
|
Invest Radiol
|
2005
|
0.96
|
|
29
|
Kinetic analysis of the cannabinoid-1 receptor PET tracer [(18)F]MK-9470 in human brain.
|
Eur J Nucl Med Mol Imaging
|
2009
|
0.96
|
|
30
|
Preclinical evaluation of 18F-JNJ41510417 as a radioligand for PET imaging of phosphodiesterase-10A in the brain.
|
J Nucl Med
|
2010
|
0.95
|
|
31
|
Radiolabeled iodohypericin as tumor necrosis avid tracer: diagnostic and therapeutic potential.
|
Int J Cancer
|
2012
|
0.93
|
|
32
|
Evaluation of tumor affinity of mono-[(123)I]iodohypericin and mono-[(123)I]iodoprotohypericin in a mouse model with a RIF-1 tumor.
|
Contrast Media Mol Imaging
|
2007
|
0.93
|
|
33
|
Non-invasive grading of brain tumours using dynamic amino acid PET imaging: does it work for 11C-methionine?
|
Eur J Nucl Med Mol Imaging
|
2007
|
0.93
|
|
34
|
18F-FDG labeling of mesenchymal stem cells and multipotent adult progenitor cells for PET imaging: effects on ultrastructure and differentiation capacity.
|
J Nucl Med
|
2013
|
0.91
|
|
35
|
Construction and evaluation of quantitative small-animal PET probabilistic atlases for [¹⁸F]FDG and [¹⁸F]FECT functional mapping of the mouse brain.
|
PLoS One
|
2013
|
0.90
|
|
36
|
In vivo quantification of calcitonin gene-related peptide receptor occupancy by telcagepant in rhesus monkey and human brain using the positron emission tomography tracer [11C]MK-4232.
|
J Pharmacol Exp Ther
|
2013
|
0.90
|
|
37
|
Metabolic-dopaminergic mapping of the 6-hydroxydopamine rat model for Parkinson's disease.
|
Eur J Nucl Med Mol Imaging
|
2007
|
0.89
|
|
38
|
Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice.
|
Acta Neuropathol
|
2015
|
0.88
|
|
39
|
Whole-body biodistribution and radiation dosimetry of the cannabinoid type 2 receptor ligand [11C]-NE40 in healthy subjects.
|
Mol Imaging Biol
|
2013
|
0.88
|
|
40
|
Changes in cerebral CB1 receptor availability after acute and chronic alcohol abuse and monitored abstinence.
|
J Neurosci
|
2014
|
0.88
|
|
41
|
Quantification of 18F-JNJ-42259152, a novel phosphodiesterase 10A PET tracer: kinetic modeling and test-retest study in human brain.
|
J Nucl Med
|
2013
|
0.88
|
|
42
|
EANM guideline for the preparation of an Investigational Medicinal Product Dossier (IMPD).
|
Eur J Nucl Med Mol Imaging
|
2014
|
0.87
|
|
43
|
Whole-body biodistribution and radiation dosimetry of the human cannabinoid type-1 receptor ligand 18F-MK-9470 in healthy subjects.
|
J Nucl Med
|
2008
|
0.87
|
|
44
|
A PET brain reporter gene system based on type 2 cannabinoid receptors.
|
J Nucl Med
|
2011
|
0.87
|
|
45
|
Synthesis and evaluation of a (99m)Tc-MAMA-propyl-thymidine complex as a potential probe for in vivo visualization of tumor cell proliferation with SPECT.
|
Nucl Med Biol
|
2007
|
0.87
|
|
46
|
Widespread decrease of type 1 cannabinoid receptor availability in Huntington disease in vivo.
|
J Nucl Med
|
2010
|
0.86
|
|
47
|
Synthesis, evaluation, and radiolabeling of new potent positive allosteric modulators of the metabotropic glutamate receptor 2 as potential tracers for positron emission tomography imaging.
|
J Med Chem
|
2012
|
0.86
|
|
48
|
Synthesis and evaluation of 18F- and 11C-labeled phenyl-galactopyranosides as potential probes for in vivo visualization of LacZ gene expression using positron emission tomography.
|
Bioconjug Chem
|
2008
|
0.86
|
|
49
|
Regional changes in type 1 cannabinoid receptor availability in Parkinson's disease in vivo.
|
Neurobiol Aging
|
2011
|
0.86
|
|
50
|
[18F]EF3 is not superior to [18F]FMISO for PET-based hypoxia evaluation as measured in a rat rhabdomyosarcoma tumour model.
|
Eur J Nucl Med Mol Imaging
|
2008
|
0.86
|
|
51
|
Optimal buffer choice of the radiosynthesis of (68)Ga-Dotatoc for clinical application.
|
Nucl Med Commun
|
2010
|
0.85
|
|
52
|
Pretargeting of necrotic tumors with biotinylated hypericin using 123I-labeled avidin: evaluation of a two-step strategy.
|
Invest New Drugs
|
2011
|
0.85
|
|
53
|
Regional brain activity in functional dyspepsia: a H(2)(15)O-PET study on the role of gastric sensitivity and abuse history.
|
Gastroenterology
|
2010
|
0.85
|
|
54
|
The impact of aggregation on the biodistribution of hypericin.
|
Int J Oncol
|
2006
|
0.85
|
|
55
|
Non-invasive imaging of neuropathology in a rat model of alpha-synuclein overexpression.
|
Neurobiol Aging
|
2006
|
0.85
|
|
56
|
Fetal gene transfer with lentiviral vectors: long-term in vivo follow-up evaluation in a rat model.
|
Am J Obstet Gynecol
|
2007
|
0.85
|
|
57
|
Is there an additional value of ¹¹C-choline PET-CT to T2-weighted MRI images in the localization of intraprostatic tumor nodules?
|
Int J Radiat Oncol Biol Phys
|
2012
|
0.84
|
|
58
|
Synthesis and preliminary evaluation of mono-[123I]iodohypericin monocarboxylic acid as a necrosis avid imaging agent.
|
Bioorg Med Chem Lett
|
2007
|
0.83
|
|
59
|
PET imaging shows loss of striatal PDE10A in patients with Huntington disease.
|
Neurology
|
2013
|
0.83
|
|
60
|
Improved synthesis and metabolic stability analysis of the dopamine transporter ligand [(18)F]FECT.
|
Nucl Med Biol
|
2007
|
0.82
|
|
61
|
Preliminary in vivo evaluation of a novel 99mTc-labeled HYNIC-cys-annexin A5 as an apoptosis imaging agent.
|
Bioorg Med Chem Lett
|
2008
|
0.82
|
|
62
|
Recent advances in positron emission tomography (PET) radiotracers for imaging phosphodiesterases.
|
Curr Top Med Chem
|
2012
|
0.82
|
|
63
|
(11)C-MK-8278 PET as a tool for pharmacodynamic brain occupancy of histamine 3 receptor inverse agonists.
|
J Nucl Med
|
2013
|
0.81
|
|
64
|
Synthesis and biological evaluation of [¹¹C]SB366791: a new PET-radioligand for in vivo imaging of the TRPV1 receptor.
|
Nucl Med Biol
|
2012
|
0.81
|
|
65
|
Evaluation of [¹⁸F]MK-0911, a positron emission tomography (PET) tracer for opioid receptor-like 1 (ORL1), in rhesus monkey and human.
|
Neuroimage
|
2012
|
0.80
|
|
66
|
Human biodistribution and dosimetry of 18F-JNJ42259152, a radioligand for phosphodiesterase 10A imaging.
|
Eur J Nucl Med Mol Imaging
|
2012
|
0.80
|
|
67
|
Synthesis and biological evaluation of (11)C-labeled beta-galactosyl triazoles as potential PET tracers for in vivo LacZ reporter gene imaging.
|
Bioorg Med Chem
|
2009
|
0.80
|
|
68
|
Effect of corticosteroids on 18F-FDG uptake in tumor lesions after chemotherapy.
|
J Nucl Med
|
2007
|
0.80
|
|
69
|
Identity confirmation of 99mTc-MAG3, 99mTc-sestamibi and 99mTc-ECD using radio-LC-MS.
|
J Pharm Biomed Anal
|
2003
|
0.80
|
|
70
|
In vivo type 1 cannabinoid receptor mapping in the 6-hydroxydopamine lesion rat model of Parkinson's disease.
|
Brain Res
|
2009
|
0.80
|
|
71
|
Small-animal PET imaging of the type 1 and type 2 cannabinoid receptors in a photothrombotic stroke model.
|
Eur J Nucl Med Mol Imaging
|
2012
|
0.80
|
|
72
|
Characterization of the novel GlyT1 PET tracer [18F]MK-6577 in humans.
|
Synapse
|
2014
|
0.80
|
|
73
|
Small animal PET imaging of the type 1 cannabinoid receptor in a rodent model for anorexia nervosa.
|
Eur J Nucl Med Mol Imaging
|
2013
|
0.80
|
|
74
|
In vitro evaluation and biodistribution of a 99mTc-labeled anti-VEGF peptide targeting neuropilin-1.
|
Nucl Med Biol
|
2004
|
0.79
|
|
75
|
Influence of chronic nicotine administration on cerebral type 1 cannabinoid receptor binding: an in vivo micro-PET study in the rat using [18F]MK-9470.
|
J Mol Neurosci
|
2010
|
0.79
|
|
76
|
Synthesis and evaluation of 18F-labeled 2-phenylbenzothiazoles as positron emission tomography imaging agents for amyloid plaques in Alzheimer's disease.
|
J Med Chem
|
2009
|
0.79
|
|
77
|
Development of a conjugate of (99m)Tc-EC with aminomethylenediphosphonate in the search for a bone tracer with fast clearance from soft tissue.
|
Bioconjug Chem
|
2002
|
0.79
|
|
78
|
Interictal type 1 cannabinoid receptor binding is increased in female migraine patients.
|
Headache
|
2011
|
0.78
|
|
79
|
Increased cerebral cannabinoid-1 receptor availability is a stable feature of functional dyspepsia: a [F]MK-9470 PET study.
|
Psychother Psychosom
|
2015
|
0.78
|
|
80
|
Transient changes in the endocannabinoid system after acute and chronic ethanol exposure and abstinence in the rat: a combined PET and microdialysis study.
|
Eur J Nucl Med Mol Imaging
|
2013
|
0.78
|
|
81
|
Development and evaluation of a 68Ga labeled pamoic acid derivative for in vivo visualization of necrosis using positron emission tomography.
|
Bioorg Med Chem
|
2010
|
0.78
|
|
82
|
Synthesis of [18F]RGD-K5 by catalyzed [3 + 2] cycloaddition for imaging integrin αvβ3 expression in vivo.
|
Nucl Med Biol
|
2013
|
0.78
|
|
83
|
The effect of anaesthesia on [(18)F]MK-9470 binding to the type 1 cannabinoid receptor in the rat brain.
|
Eur J Nucl Med Mol Imaging
|
2010
|
0.78
|
|
84
|
An in vivo [18F]MK-9470 microPET study of type 1 cannabinoid receptor binding in Wistar rats after chronic administration of valproate and levetiracetam.
|
Neuropharmacology
|
2008
|
0.78
|
|
85
|
Synthesis, in vivo occupancy, and radiolabeling of potent phosphodiesterase subtype-10 inhibitors as candidates for positron emission tomography imaging.
|
J Med Chem
|
2011
|
0.78
|
|
86
|
Influence of chronic bromocriptine and levodopa administration on cerebral type 1 cannabinoid receptor binding.
|
Synapse
|
2010
|
0.78
|
|
87
|
Preclinical evaluation and quantification of [¹⁸F]MK-9470 as a radioligand for PET imaging of the type 1 cannabinoid receptor in rat brain.
|
Eur J Nucl Med Mol Imaging
|
2012
|
0.78
|
|
88
|
Motor- and food-related metabolic cerebral changes in the activity-based rat model for anorexia nervosa: a voxel-based microPET study.
|
Neuroimage
|
2006
|
0.77
|
|
89
|
A nonsurgical porcine model of left ventricular dysfunction. Validation of myocardial viability using dobutamine stress echocardiography and positron emission tomography.
|
Int J Cardiovasc Intervent
|
2000
|
0.77
|
|
90
|
Radiolabeling and preliminary biological evaluation of a (99m)Tc(CO)(3) labeled 3,3'-(benzylidene)-bis-(1H-indole-2-carbohydrazide) derivative as a potential SPECT tracer for in vivo visualization of necrosis.
|
Bioorg Med Chem Lett
|
2010
|
0.77
|
|
91
|
Type 1 cannabinoid receptor mapping with [18F]MK-9470 PET in the rat brain after quinolinic acid lesion: a comparison to dopamine receptors and glucose metabolism.
|
Eur J Nucl Med Mol Imaging
|
2010
|
0.77
|
|
92
|
In vivo characterization and dynamic receptor occupancy imaging of TPA023B, an alpha 2/alpha 3/alpha 5 subtype selective gamma-aminobutyric acid-a partial agonist.
|
Biol Psychiatry
|
2008
|
0.77
|
|
93
|
The presence of ethanol in radiopharmaceutical injections.
|
J Nucl Med
|
2008
|
0.77
|
|
94
|
The effect of a methyl or 2-fluoroethyl substituent at the N-3 position of thymidine, 3'-fluoro-3'-deoxythymidine and 1-beta-D-arabinosylthymine on their antiviral and cytostatic activity in cell culture.
|
Antivir Chem Chemother
|
2006
|
0.76
|
|
95
|
Accumulation and photocytotoxicity of hypericin and analogs in two- and three-dimensional cultures of transitional cell carcinoma cells.
|
Photochem Photobiol
|
2003
|
0.76
|
|
96
|
New transient receptor potential vanilloid subfamily member 1 positron emission tomography radioligands: synthesis, radiolabeling, and preclinical evaluation.
|
ACS Chem Neurosci
|
2013
|
0.75
|
|
97
|
Synthetic strategies for radioligands for in vivo imaging of brain cannabinoid type-1 receptors.
|
J Labelled Comp Radiopharm
|
2013
|
0.75
|
|
98
|
Characterisation and biodistribution of two neutral 99mTc(CO)3 complexes with a tridentate ligand.
|
Bioorg Med Chem Lett
|
2005
|
0.75
|
|
99
|
Synthesis and evaluation of three 18F-labeled aminophenylbenzothiazoles as amyloid imaging agents.
|
J Med Chem
|
2009
|
0.75
|
|
100
|
Pretargeted PET imaging using a bioorthogonal 18F-labeled trans-cyclooctene in an ovarian carcinoma model.
|
Bioconjug Chem
|
2017
|
0.75
|
|
101
|
Development and biological evaluation of 99mTc-BAT-tropane esters.
|
Nucl Med Biol
|
2005
|
0.75
|
|
102
|
Synthesis and biological evaluation of 68Ga labeled bis-DOTA-3,3'-(benzylidene)-bis-(1H-indole-2-carbohydrazide) as a PET tracer for in vivo visualization of necrosis.
|
Bioorg Med Chem Lett
|
2013
|
0.75
|
|
103
|
Lack of endogenous opioid release during sustained visceral pain: a [11C]carfentanil PET study.
|
Pain
|
2013
|
0.75
|
|
104
|
99mTc-tricarbonyl labeled agents for cell labeling: development, biodistribution in normal mice and preliminary in vitro evaluation.
|
Bioorg Med Chem
|
2009
|
0.75
|