Hak-Kim Chan

Author PubWeight™ 83.09‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Recommendations for the standardisation of oxytocin nasal administration and guidelines for its reporting in human research. Psychoneuroendocrinology 2012 3.30
2 Responsiveness to three bronchial provocation tests in patients with asthma. Chest 2003 1.49
3 Effect of design on the performance of a dry powder inhaler using computational fluid dynamics. Part 2: Air inlet size. J Pharm Sci 2006 1.18
4 Effect of design on the performance of a dry powder inhaler using computational fluid dynamics. Part 1: Grid structure and mouthpiece length. J Pharm Sci 2004 1.17
5 In vitro/in vivo comparisons in pulmonary drug delivery. J Aerosol Med Pulm Drug Deliv 2008 1.15
6 Nano spray drying: a novel method for preparing protein nanoparticles for protein therapy. Int J Pharm 2010 1.11
7 Formation, characterization, and fate of inhaled drug nanoparticles. Adv Drug Deliv Rev 2010 1.11
8 Influence of air flow on the performance of a dry powder inhaler using computational and experimental analyses. Pharm Res 2005 1.10
9 How much particle surface corrugation is sufficient to improve aerosol performance of powders? Pharm Res 2005 1.08
10 In vitro and in vivo aspects of cascade impactor tests and inhaler performance: a review. AAPS PharmSciTech 2007 1.07
11 Mannitol as a challenge test to identify exercise-induced bronchoconstriction in elite athletes. Am J Respir Crit Care Med 2002 1.06
12 Pulmonary formulations: what remains to be done? J Aerosol Med Pulm Drug Deliv 2010 1.05
13 What is a suitable dissolution method for drug nanoparticles? Pharm Res 2008 1.01
14 Prediction of treatment-response to inhaled corticosteroids by mannitol-challenge test in COPD. A proof of concept. Pulm Pharmacol Ther 2004 1.00
15 Preparation and characterisation of controlled release co-spray dried drug-polymer microparticles for inhalation 2: evaluation of in vitro release profiling methodologies for controlled release respiratory aerosols. Eur J Pharm Biopharm 2008 0.98
16 Pulmonary delivery of therapeutic siRNA. Adv Drug Deliv Rev 2011 0.98
17 Electrostatic charge characteristics of aerosols produced from metered dose inhalers. J Pharm Sci 2005 0.97
18 The role of capsule on the performance of a dry powder inhaler using computational and experimental analyses. Pharm Res 2005 0.97
19 Coughing during mannitol challenge is associated with asthma. Chest 2004 0.95
20 A simple relationship between dielectric constant of mixed solvents with solvent composition and temperature. Int J Pharm 2004 0.94
21 Liposomal formulations for inhalation. Ther Deliv 2013 0.94
22 Dissociation in the effect of nedocromil on mannitol-induced cough or bronchoconstriction in asthmatic subjects. Respirology 2005 0.94
23 The influence of drug morphology on aerosolisation efficiency of dry powder inhaler formulations. J Pharm Sci 2008 0.92
24 SPECT Imaging for Radioaerosol Deposition and Clearance Studies. J Aerosol Med 2006 0.92
25 Influence of humidity on the electrostatic charge and aerosol performance of dry powder inhaler carrier based systems. Pharm Res 2007 0.91
26 Influence of mouthpiece geometry on the aerosol delivery performance of a dry powder inhaler. Pharm Res 2007 0.91
27 Particle aerosolisation and break-up in dry powder inhalers 1: evaluation and modelling of venturi effects for agglomerated systems. Pharm Res 2010 0.90
28 Effect of powder polydispersity on aerosol generation. J Pharm Pharm Sci 2002 0.89
29 Effect of amino acids on the dispersion of disodium cromoglycate powders. J Pharm Sci 2005 0.89
30 Preparation and characterisation of controlled release co-spray dried drug-polymer microparticles for inhalation 1: influence of polymer concentration on physical and in vitro characteristics. Eur J Pharm Biopharm 2007 0.87
31 Inhaled antibiotics to treat lung infection. Pharm Pat Anal 2013 0.87
32 Solubility prediction in supercritical CO(2) using minimum number of experiments. J Pharm Sci 2002 0.87
33 Micro-particle corrugation, adhesion and inhalation aerosol efficiency. Eur J Pharm Sci 2008 0.86
34 The use of computational approaches in inhaler development. Adv Drug Deliv Rev 2011 0.86
35 Modifying the release properties of liposomes toward personalized medicine. J Pharm Sci 2014 0.86
36 Effect of device design on the aerosolization of a carrier-based dry powder inhaler--a case study on Aerolizer(®) Foradile (®). AAPS J 2013 0.86
37 Sensitivity and validity of three bronchial provocation tests to demonstrate the effect of inhaled corticosteroids in asthma. Chest 2003 0.86
38 Isoniazid proliposome powders for inhalation-preparation, characterization and cell culture studies. Int J Mol Sci 2011 0.84
39 Co-spray-dried mannitol-ciprofloxacin dry powder inhaler formulation for cystic fibrosis and chronic obstructive pulmonary disease. Eur J Pharm Sci 2010 0.84
40 Pharmacopeial methodologies for determining aerodynamic mass distributions of ultra-high dose inhaler medicines. J Pharm Biomed Anal 2009 0.84
41 Does the United States Pharmacopeia throat introduce de-agglomeration of carrier-free powder from inhalers? Pharm Res 2012 0.84
42 Aerosol performance and long-term stability of surfactant-associated liposomal ciprofloxacin formulations with modified encapsulation and release properties. AAPS PharmSciTech 2014 0.83
43 Can low-dose combination products for inhalation be formulated in single crystalline particles? Eur J Pharm Sci 2010 0.83
44 Recent advances in controlled release pulmonary therapy. Curr Drug Deliv 2009 0.83
45 Measuring charge and mass distributions in dry powder inhalers using the electrical Next Generation Impactor (eNGI). Eur J Pharm Sci 2009 0.83
46 The role of particle properties in pharmaceutical powder inhalation formulations. J Aerosol Med 2002 0.82
47 The influence of mechanical processing of dry powder inhaler carriers on drug aerosolization performance. J Pharm Sci 2007 0.82
48 Cospray dried antibiotics for dry powder lung delivery. J Pharm Sci 2008 0.82
49 Effect of particle size of dry powder mannitol on the lung deposition in healthy volunteers. Int J Pharm 2007 0.81
50 Overcoming dose limitations using the orbital(®) multi-breath dry powder inhaler. J Aerosol Med Pulm Drug Deliv 2013 0.80
51 Electrostatics in pharmaceutical aerosols for inhalation. Ther Deliv 2013 0.80
52 Personalizing aerosol medicine: development of delivery systems tailored to the individual. Ther Deliv 2010 0.80
53 Preparation and evaluation of controlled release microparticles for respiratory protein therapy. J Pharm Sci 2009 0.80
54 Electrostatics of pharmaceutical inhalation aerosols. J Pharm Pharmacol 2009 0.80
55 Lactose composite carriers for respiratory delivery. Pharm Res 2008 0.80
56 Particle aerosolisation and break-up in dry powder inhalers: evaluation and modelling of the influence of grid structures for agglomerated systems. J Pharm Sci 2011 0.80
57 Standardization of techniques for using single-photon emission computed tomography (SPECT) for aerosol deposition assessment of orally inhaled products. J Aerosol Med Pulm Drug Deliv 2012 0.80
58 A solid-state NMR study of protein mobility in lyophilized protein-sugar powders. J Pharm Sci 2002 0.80
59 Impact angles as an alternative way to improve aerosolisation of powders for inhalation? Eur J Pharm Sci 2010 0.79
60 Constant size, variable density aerosol particles by ultrasonic spray freeze drying. Int J Pharm 2012 0.79
61 Feasibility of preparing nanodrugs by high-gravity reactive precipitation. Int J Pharm 2004 0.79
62 Effect of relative humidity on the electrostatic charge properties of dry powder inhaler aerosols. Pharm Res 2007 0.79
63 Effect of crystallinity on electrostatic charging in dry powder inhaler formulations. Pharm Res 2014 0.78
64 Mannitol delivery by vibrating mesh nebulisation for enhancing mucociliary clearance. J Pharm Sci 2011 0.78
65 Powder Production and Particle Engineering for Dry Powder Inhaler Formulations. Curr Pharm Des 2015 0.78
66 The contribution of different formulation components on the aerosol charge in carrier-based dry powder inhaler systems. Pharm Res 2010 0.78
67 Electrostatic charge characteristics of jet nebulized aerosols. J Aerosol Med Pulm Drug Deliv 2010 0.78
68 Aerosol delivery of nanoparticles in uniform mannitol carriers formulated by ultrasonic spray freeze drying. Pharm Res 2013 0.78
69 Multi-scale modelling of powder dispersion in a carrier-based inhalation system. Pharm Res 2014 0.78
70 Delivery of high solubility polyols by vibrating mesh nebulizer to enhance mucociliary clearance. J Aerosol Med Pulm Drug Deliv 2012 0.78
71 Development of an in vivo ovine dry powder inhalation model for the evaluation of conventional and controlled release microparticles. AAPS J 2009 0.78
72 Solubility prediction of paracetamol in binary and ternary solvent mixtures using Jouyban-Acree model. Chem Pharm Bull (Tokyo) 2006 0.77
73 Controlled release antibiotics for dry powder lung delivery. Drug Dev Ind Pharm 2010 0.77
74 Enhanced dissolution of inhalable cyclosporine nano-matrix particles with mannitol as matrix former. Int J Pharm 2011 0.77
75 Inhalation challenge with bovine dander allergens: who needs it? Chest 2003 0.77
76 Advances in device and formulation technologies for pulmonary drug delivery. AAPS PharmSciTech 2014 0.77
77 Preparation of inhalable salbutamol sulphate using reactive high gravity controlled precipitation. J Pharm Sci 2008 0.77
78 Novel alternatives to reduce powder retention in the dry powder inhaler during aerosolization. Int J Pharm 2013 0.77
79 TLR2-targeted secreted proteins from Mycobacterium tuberculosis are protective as powdered pulmonary vaccines. Vaccine 2013 0.77
80 The effect of ethanol on the formation and physico-chemical properties of particles generated from budesonide solution-based pressurized metered-dose inhalers. Drug Dev Ind Pharm 2013 0.77
81 Formation of protein nano-matrix particles with controlled surface architecture for respiratory drug delivery. Pharm Res 2010 0.77
82 Method to introduce mannitol powder to intubated patients to improve sputum clearance. J Aerosol Med Pulm Drug Deliv 2010 0.77
83 Production of salbutamol sulfate for inhalation by high-gravity controlled antisolvent precipitation. Int J Pharm 2006 0.77
84 Does electrostatic charge affect powder aerosolisation? J Pharm Sci 2010 0.76
85 A novel inhalable form of rifapentine. J Pharm Sci 2014 0.76
86 Pulmonary drug delivery. Ther Deliv 2013 0.76
87 Introduction of the electrical next generation impactor (eNGI) and investigation of its capabilities for the study of pressurized metered dose inhalers. Pharm Res 2008 0.76
88 Nanodrug particles and nanoformulations for drug delivery. Adv Drug Deliv Rev 2011 0.76
89 Physicochemical characterization and stability of rifampicin liposome dry powder formulations for inhalation. J Pharm Sci 2009 0.76
90 Generation of fine powders of recombinant human deoxyribonuclease using the aerosol solvent extraction system. Pharm Res 2003 0.76
91 Evaluation on the use of confined liquid impinging jets for the synthesis of nanodrug particles. Drug Dev Ind Pharm 2008 0.76
92 The future perspectives of natural materials for pulmonary drug delivery and lung tissue engineering. Expert Opin Drug Deliv 2014 0.75
93 Unitary hormonal models, peripheral markers, and evaluation of response to drug: a response to Weisman and Feldman. Psychoneuroendocrinology 2013 0.75
94 Steroid-decorated antibiotic microparticles for inhaled anti-infective therapy. J Pharm Sci 2014 0.75
95 The influence of flow rate on the aerosol deposition profile and electrostatic charge of single and combination metered dose inhalers. Pharm Res 2009 0.75
96 NanoXCT: a novel technique to probe the internal architecture of pharmaceutical particles. Pharm Res 2014 0.75
97 Modeling the entrainer effects on solubility of solutes in supercritical carbon dioxide. Chem Pharm Bull (Tokyo) 2005 0.75
98 Mathematical representation of apparent dissociation constants in aqueous-organic solvent mixtures. Int J Pharm 2002 0.75
99 Effect of mouthpiece washing on aerosol performance of CFC-free Ventolin. J Asthma 2004 0.75
100 Editorial: Emerging Formulation Design and Drug Delivery Systems for Inhaled Therapy. Curr Pharm Des 2015 0.75
101 Comparison of different algorithms to calculate electrophoretic mobility of analytes as a function of binary solvent composition. Electrophoresis 2003 0.75
102 A rifapentine-containing inhaled triple antibiotic formulation for rapid treatment of tubercular infection. Pharm Res 2013 0.75
103 Solubility prediction of anthracene in mixed solvents using a minimum number of experimental data. Chem Pharm Bull (Tokyo) 2002 0.75
104 Dissolution kinetic behavior of drug nanoparticles and their conformity to the diffusion model. Langmuir 2008 0.75
105 Discrete Modelling of Powder Dispersion in Dry Powder Inhalers - A Brief Review. Curr Pharm Des 2015 0.75
106 Multi-breath dry powder inhaler for delivery of cohesive powders in the treatment of bronchiectasis. Drug Dev Ind Pharm 2014 0.75
107 Inhalable dry powder formulations of siRNA and pH-responsive peptides with antiviral activity against H1N1 influenza virus. Mol Pharm 2015 0.75
108 A cosolvency model to predict solubility of drugs at several temperatures from a limited number of solubility measurements. Chem Pharm Bull (Tokyo) 2002 0.75
109 A novel method for the production of crystalline micronised particles. Int J Pharm 2010 0.75
110 A unified cosolvency model for calculating solute solubility in mixed solvents. Chem Pharm Bull (Tokyo) 2005 0.75
111 Isothermal microcalorimetry of pressurized systems I: a rapid method to evaluate pressurized metered dose inhaler formulations. Pharm Res 2014 0.75
112 Focused-ion-beam milling: a novel approach to probing the interior of particles used for inhalation aerosols. Pharm Res 2007 0.75
113 Validation of radiolabeling of drug formulations for aerosol deposition assessment of orally inhaled products. J Aerosol Med Pulm Drug Deliv 2012 0.75
114 Lung deposition of mannitol powder aerosol in healthy subjects. J Aerosol Med 2006 0.75
115 Isothermal microcalorimetry of pressurized systems II: effect of excipient and water ingress on formulation stability of amorphous glycopyrrolate. Pharm Res 2014 0.75
116 The use of organic vapor sorption to determine low levels of amorphous content in processed pharmaceutical powders. Drug Dev Ind Pharm 2007 0.75
117 Scanning white-light interferometry as a novel technique to quantify the surface roughness of micron-sized particles for inhalation. Langmuir 2008 0.75