Published in Trends Biochem Sci on January 07, 2008
Extracellular heat shock proteins, cellular export vesicles, and the Stress Observation System: a form of communication during injury, infection, and cell damage. It is never known how far a controversial finding will go! Dedicated to Ferruccio Ritossa. Cell Stress Chaperones (2010) 1.69
The role of heat shock proteins in antigen cross presentation. Front Immunol (2012) 1.33
Caught with their PAMPs down? The extracellular signalling actions of molecular chaperones are not due to microbial contaminants. Cell Stress Chaperones (2010) 1.31
Hsp60 is actively secreted by human tumor cells. PLoS One (2010) 1.27
Excretory/secretory proteome of the adult developmental stage of human blood fluke, Schistosoma japonicum. Mol Cell Proteomics (2009) 1.27
Radiation, inflammation, and immune responses in cancer. Front Oncol (2012) 1.25
Heat shock protein 90 mediates efficient antigen cross presentation through the scavenger receptor expressed by endothelial cells-I. J Immunol (2010) 1.20
Intracellular heat shock protein-70 negatively regulates TLR4 signaling in the newborn intestinal epithelium. J Immunol (2012) 1.15
Heat shock proteins and cancer vaccines: developments in the past decade and chaperoning in the decade to come. Expert Rev Vaccines (2011) 1.11
Heat shock proteins as biomarkers for the rapid detection of brain and spinal cord ischemia: a review and comparison to other methods of detection in thoracic aneurysm repair. Cell Stress Chaperones (2010) 1.07
Elevated blood Hsp60, its structural similarities and cross-reactivity with thyroid molecules, and its presence on the plasma membrane of oncocytes point to the chaperonin as an immunopathogenic factor in Hashimoto's thyroiditis. Cell Stress Chaperones (2013) 1.05
Novel roles of peroxiredoxins in inflammation, cancer and innate immunity. J Clin Biochem Nutr (2012) 1.04
Extracellular heat shock protein 70 (HSPA1A) and classical vascular risk factors in a general population. Cell Stress Chaperones (2010) 1.04
Circulating heat shock protein 70 (HSPA1A) in normal and pathological pregnancies. Cell Stress Chaperones (2009) 1.02
Distinguishing integral and receptor-bound heat shock protein 70 (Hsp70) on the cell surface by Hsp70-specific antibodies. Cell Stress Chaperones (2010) 1.02
MultitaskProtDB: a database of multitasking proteins. Nucleic Acids Res (2013) 1.02
Hsp60 and Hsp10 increase in colon mucosa of Crohn’s disease and ulcerative colitis. Cell Stress Chaperones (2010) 1.01
The human HSP70 family of chaperones: where do we stand? Cell Stress Chaperones (2016) 0.95
The odyssey of Hsp60 from tumor cells to other destinations includes plasma membrane-associated stages and Golgi and exosomal protein-trafficking modalities. PLoS One (2012) 0.95
Inactivation of the hereditary spastic paraplegia-associated Hspd1 gene encoding the Hsp60 chaperone results in early embryonic lethality in mice. Cell Stress Chaperones (2010) 0.93
Calcium signaling in dendritic cells by human or mycobacterial Hsp70 is caused by contamination and is not required for Hsp70-mediated enhancement of cross-presentation. J Biol Chem (2008) 0.92
Hsp70 and cardiac surgery: molecular chaperone and inflammatory regulator with compartmentalized effects. Cell Stress Chaperones (2008) 0.90
Gene transcription profile of the detached retina (An AOS Thesis). Trans Am Ophthalmol Soc (2009) 0.89
HPV Vaccines: today and in the Future. J Adolesc Health (2008) 0.88
In vivo rescue of alveolar macrophages from SP-A knockout mice with exogenous SP-A nearly restores a wild type intracellular proteome; actin involvement. Proteome Sci (2011) 0.88
Heat shock protein 70: roles in multiple sclerosis. Mol Med (2012) 0.87
Circulating anti-heat-shock-protein antibodies in normal pregnancy and preeclampsia. Cell Stress Chaperones (2009) 0.87
Presence of circulating anti-myosin antibodies in endomyocardial fibrosis. PLoS Negl Trop Dis (2010) 0.86
Toll-like receptor signaling in transplantation. Curr Opin Organ Transplant (2008) 0.86
Specific microtubule-depolymerizing agents augment efficacy of dendritic cell-based cancer vaccines. J Biomed Sci (2011) 0.86
Excretory/secretory proteome of the adult stage of Echinostoma caproni. Parasitol Res (2010) 0.86
Extracellular heat shock proteins: a new location, a new function. Shock (2013) 0.85
Autoreactive HSP60 epitope-specific T-cells in early human atherosclerotic lesions. J Autoimmun (2012) 0.84
Modulation of Human Macrophage Responses to Mycobacterium tuberculosis by Silver Nanoparticles of Different Size and Surface Modification. PLoS One (2015) 0.84
Heat-shock protein 60 kDa and atherogenic dyslipidemia in patients with untreated mild periodontitis: a pilot study. Cell Stress Chaperones (2012) 0.83
Mitochondrial DNA variability modulates mRNA and intra-mitochondrial protein levels of HSP60 and HSP75: experimental evidence from cybrid lines. Cell Stress Chaperones (2008) 0.83
The effect of the rate of heat storage on serum heat shock protein 72 in humans. Eur J Appl Physiol (2008) 0.83
HSP60: issues and insights on its therapeutic use as an immunoregulatory agent. Front Immunol (2012) 0.83
Pediatric Sepsis - Part V: Extracellular Heat Shock Proteins: Alarmins for the Host Immune System. Open Inflamm J (2011) 0.82
Sex differences in the response of the alveolar macrophage proteome to treatment with exogenous surfactant protein-A. Proteome Sci (2012) 0.82
No endogenous circadian rhythm in resting plasma Hsp72 concentration in humans. Cell Stress Chaperones (2008) 0.81
Evidence for a role of autoantibodies to heat shock protein 60, 70, and 90 in patients with dermatitis herpetiformis. Cell Stress Chaperones (2014) 0.80
Amygdalin analogues inhibit IFN-γ signalling and reduce the inflammatory response in human epidermal keratinocytes. Inflammation (2013) 0.79
Sex differences in the acute in vivo effects of different human SP-A variants on the mouse alveolar macrophage proteome. J Proteomics (2014) 0.79
Identification of a heat shock cognate protein 70 gene in Chinese soft-shell turtle (Pelodiscus sinensis) and its expression profiles under thermal stress. J Zhejiang Univ Sci B (2012) 0.78
Heat shock protein 72 expressing stress in sepsis: unbridgeable gap between animal and human studies--a hypothetical "comparative" study. Biomed Res Int (2014) 0.78
Identification of peptide mimotopes of gp96 using single-chain antibody library. Cell Stress Chaperones (2010) 0.78
Prevention and treatment of alopecia areata with quercetin in the C3H/HeJ mouse model. Cell Stress Chaperones (2011) 0.78
Heat Shock Proteins: Intestinal Gatekeepers that Are Influenced by Dietary Components and the Gut Microbiota. Pathogens (2014) 0.78
EEVD motif of heat shock cognate protein 70 contributes to bacterial uptake by trophoblast giant cells. J Biomed Sci (2009) 0.77
Immune tolerance therapies for autoimmune diseases based on heat shock protein T-cell epitopes. Philos Trans R Soc Lond B Biol Sci (2018) 0.76
Extracellular cell stress (heat shock) proteins-immune responses and disease: an overview. Philos Trans R Soc Lond B Biol Sci (2018) 0.76
Chaperoned amyloid proteins for immune manipulation: α-Synuclein/Hsp70 shifts immunity toward a modulatory phenotype. Immun Inflamm Dis (2014) 0.76
Potential Response to Selection of HSP70 as a Component of Innate Immunity in the Abalone Haliotis rufescens. PLoS One (2015) 0.76
Plant Hsp90 proteins interact with B-cells and stimulate their proliferation. PLoS One (2011) 0.76
Fasting enhances TRAIL-mediated liver natural killer cell activity via HSP70 upregulation. PLoS One (2014) 0.75
T cell recognition of naturally presented epitopes of self-heat shock protein 70. Cell Stress Chaperones (2014) 0.75
Non-Lethal Heat Shock of the Asian Green Mussel, Perna viridis, Promotes Hsp70 Synthesis, Induces Thermotolerance and Protects Against Vibrio Infection. PLoS One (2015) 0.75
Bioactivity of food peptides: biological response of rats to bovine milk whey peptides following acute exercise. Food Nutr Res (2017) 0.75
Quantitative patterns of Hsps in tubular adenoma compared with normal and tumor tissues reveal the value of Hsp10 and Hsp60 in early diagnosis of large bowel cancer. Cell Stress Chaperones (2016) 0.75
Sertolin mediates blood-testis barrier restructuring. Endocrinology (2014) 0.75
The Hsp72 response in peri-parturient dairy cows: relationships with metabolic and immunological parameters. Cell Stress Chaperones (2010) 0.75
Skin mucus proteins of lumpsucker (Cyclopterus lumpus). Biochem Biophys Rep (2017) 0.75
AV119, a natural sugar from avocado gratissima, modulates the LPS-induced proinflammatory response in human keratinocytes. Inflammation (2011) 0.75
The role of myeloid cells in the promotion of tumour angiogenesis. Nat Rev Cancer (2008) 7.40
Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4. J Biol Chem (2002) 6.16
Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implications. Cell Stress Chaperones (2005) 5.22
Hypoxia regulates macrophage functions in inflammation. J Immunol (2005) 2.19
Heat shock protein 70 is secreted from tumor cells by a nonclassical pathway involving lysosomal endosomes. J Immunol (2006) 2.13
Induction of heat shock proteins by heregulin beta1 leads to protection from apoptosis and anchorage-independent growth. Oncogene (2005) 1.64
OSU-03012 stimulates PKR-like endoplasmic reticulum-dependent increases in 70-kDa heat shock protein expression, attenuating its lethal actions in transformed cells. Mol Pharmacol (2008) 1.52
Role of scavenger receptors in the binding and internalization of heat shock protein 70. J Immunol (2006) 1.48
The anti-inflammatory effects of heat shock protein 72 involve inhibition of high-mobility-group box 1 release and proinflammatory function in macrophages. J Immunol (2007) 1.43
Heat shock factor 1 represses transcription of the IL-1beta gene through physical interaction with the nuclear factor of interleukin 6. J Biol Chem (2002) 1.43
Mechanisms for Hsp70 secretion: crossing membranes without a leader. Methods (2007) 1.42
Expression of heat shock proteins and heat shock protein messenger ribonucleic acid in human prostate carcinoma in vitro and in tumors in vivo. Cell Stress Chaperones (2005) 1.41
Induction of hsp70-mediated Th17 autoimmunity can be exploited as immunotherapy for metastatic prostate cancer. Cancer Res (2007) 1.37
Angiopoietin 2 stimulates TIE2-expressing monocytes to suppress T cell activation and to promote regulatory T cell expansion. J Immunol (2011) 1.35
Tumor-derived heat shock protein 70 peptide complexes are cross-presented by human dendritic cells. J Immunol (2002) 1.34
Extracellular HSP70 binding to surface receptors present on antigen presenting cells and endothelial/epithelial cells. FEBS Lett (2005) 1.34
The role of heat shock proteins in antigen cross presentation. Front Immunol (2012) 1.33
Targeting the oncogene and kinome chaperone CDC37. Nat Rev Cancer (2008) 1.32
Caught with their PAMPs down? The extracellular signalling actions of molecular chaperones are not due to microbial contaminants. Cell Stress Chaperones (2010) 1.31
A heat shock protein 70-based vaccine with enhanced immunogenicity for clinical use. J Immunol (2009) 1.28
mTOR is essential for the proteotoxic stress response, HSF1 activation and heat shock protein synthesis. PLoS One (2012) 1.25
Phosphorylation of HSF1 by MAPK-activated protein kinase 2 on serine 121, inhibits transcriptional activity and promotes HSP90 binding. J Biol Chem (2005) 1.22
Heat shock protein 90 mediates efficient antigen cross presentation through the scavenger receptor expressed by endothelial cells-I. J Immunol (2010) 1.20
Heat-shock proteins in cancer vaccines: agents of antigen cross-presentation. Expert Rev Vaccines (2008) 1.19
Targeting Cdc37 inhibits multiple signaling pathways and induces growth arrest in prostate cancer cells. Cancer Res (2007) 1.19
Regulation of molecular chaperone gene transcription involves the serine phosphorylation, 14-3-3 epsilon binding, and cytoplasmic sequestration of heat shock factor 1. Mol Cell Biol (2003) 1.18
Enhanced immunogenicity of heat shock protein 70 peptide complexes from dendritic cell-tumor fusion cells. J Immunol (2006) 1.16
Heat shock proteins and cancer vaccines: developments in the past decade and chaperoning in the decade to come. Expert Rev Vaccines (2011) 1.11
Elevated expression of heat shock factor (HSF) 2A stimulates HSF1-induced transcription during stress. J Biol Chem (2003) 1.10
The inhibition of LPS-induced production of inflammatory cytokines by HSP70 involves inactivation of the NF-kappaB pathway but not the MAPK pathways. Shock (2006) 1.10
Co-expression of steroid receptors (estrogen receptor alpha and/or progesterone receptors) and Her-2/neu: Clinical implications. J Steroid Biochem Mol Biol (2006) 1.09
Antitumor immunity can be uncoupled from autoimmunity following heat shock protein 70-mediated inflammatory killing of normal pancreas. Cancer Res (2009) 1.09
OstemiR: a novel panel of microRNA biomarkers in osteoblastic and osteocytic differentiation from mesencymal stem cells. PLoS One (2013) 1.09
The atheroprotective properties of Hsp70: a role for Hsp70-endothelial interactions? Cell Stress Chaperones (2009) 1.08
Mathematical modeling predicts synergistic antitumor effects of combining a macrophage-based, hypoxia-targeted gene therapy with chemotherapy. Cancer Res (2011) 1.07
T cell activation by heat shock protein 70 vaccine requires TLR signaling and scavenger receptor expressed by endothelial cells-1. J Immunol (2009) 1.05
Transcriptional activity and DNA binding of heat shock factor-1 involve phosphorylation on threonine 142 by CK2. Biochem Biophys Res Commun (2003) 1.03
Protein kinase A binds and activates heat shock factor 1. PLoS One (2010) 1.02
Metastasis is an early event in mouse mammary carcinomas and is associated with cells bearing stem cell markers. Breast Cancer Res (2012) 1.02
Heat induced release of Hsp70 from prostate carcinoma cells involves both active secretion and passive release from necrotic cells. Int J Hyperthermia (2006) 1.02
Double-stranded RNA-dependent protein kinase (pkr) is essential for thermotolerance, accumulation of HSP70, and stabilization of ARE-containing HSP70 mRNA during stress. J Biol Chem (2002) 1.00
Interactions between extracellular signal-regulated protein kinase 1, 14-3-3epsilon, and heat shock factor 1 during stress. J Biol Chem (2004) 0.99
Induction of cytotoxic T lymphocytes against ovarian cancer-initiating cells. Int J Cancer (2011) 0.98
Expression of a dominant negative heat shock factor-1 construct inhibits aneuploidy in prostate carcinoma cells. J Biol Chem (2004) 0.97
Cell fusion: from hybridoma to dendritic cell-based vaccine. Expert Rev Vaccines (2008) 0.95
NF-IL6 and HSF1 have mutually antagonistic effects on transcription in monocytic cells. Biochem Biophys Res Commun (2002) 0.93
Immunotherapy of radioresistant mammary tumors with early metastasis using molecular chaperone vaccines combined with ionizing radiation. J Immunol (2013) 0.93
Heat shock proteins and allograft rejection. Contrib Nephrol (2005) 0.91
Heat shock factor 1 contains two functional domains that mediate transcriptional repression of the c-fos and c-fms genes. J Biol Chem (2002) 0.91
Protein kinase A regulates molecular chaperone transcription and protein aggregation. PLoS One (2011) 0.90
Stress proteins in aging and life span. Int J Hyperthermia (2013) 0.90
Administration of the stress protein gp96 prolongs rat cardiac allograft survival, modifies rejection-associated inflammatory events, and induces a state of peripheral T-cell hyporesponsiveness. Cell Stress Chaperones (2007) 0.90
The stress protein gp96 is not an activator of resting rat bone marrow-derived dendritic cells, but is a costimulator and activator of CD3+ T cells. Cell Stress Chaperones (2006) 0.90
Oxidative stress impairs the heat stress response and delays unfolded protein recovery. PLoS One (2009) 0.90
Investigating receptors for extracellular heat shock proteins. Methods Mol Biol (2011) 0.87
Autophagy, protein aggregation and hyperthermia: a mini-review. Int J Hyperthermia (2011) 0.87
Plasma heat shock protein 72 as a biomarker of sarcopenia in elderly people. Cell Stress Chaperones (2011) 0.85
Plasma adenosine triphosphate and heat shock protein 72 concentrations after aerobic and eccentric exercise. Exerc Immunol Rev (2011) 0.84
Purification, preparation, and use of chaperone-peptide complexes for tumor immunotherapy. Methods Mol Biol (2013) 0.82
The role of histone deacetylases in rheumatoid arthritis fibroblast-like synoviocytes. Biochem Soc Trans (2013) 0.81
Hyperthermia classic article commentary: 'Re-induction of hsp70 synthesis: an assay for thermotolerance' by Gloria C. Li and Johnson Y. Mak, International Journal of Hyperthermia 1989;5:389-403. Int J Hyperthermia (2009) 0.81
Khat (Catha edulis) alters the phenotype and anti-microbial activity of peripheral blood mononuclear cells. J Ethnopharmacol (2011) 0.80
A peptide derived from TIMP-3 inhibits multiple angiogenic growth factor receptors and tumour growth and inflammatory arthritis in mice. Angiogenesis (2013) 0.79
The role of heat shock factors in stress-induced transcription. Methods Mol Biol (2011) 0.79
A non-receptor-mediated mechanism for internalization of molecular chaperones. Methods (2007) 0.78
Radiosensitization of mammary carcinoma cells by telomere homolog oligonucleotide pretreatment. Breast Cancer Res (2010) 0.78
Preparation of a heat-shock protein 70-based vaccine from DC-tumor fusion cells. Methods Mol Biol (2011) 0.78
Heat shock proteins in physiology and pathology: the Berlin meeting. Cell Stress Chaperones (2007) 0.77
From stress protein biochemistry to novel immunotherapeutics. Int J Hyperthermia (2013) 0.75