Published in Am J Hematol on May 01, 2008
Adult-onset Still disease: a rare disorder with a potentially fatal outcome. Auto Immun Highlights (2010) 0.82
Successful Tocilizumab Therapy for Macrophage Activation Syndrome Associated with Adult-Onset Still's Disease: A Case-Based Review. Case Rep Med (2016) 0.75
New-onset seizures in two adults with hemophagocytic lymphohistiocytosis. J Neurol (2015) 0.75
WHO-EORTC classification for cutaneous lymphomas. Blood (2005) 12.14
Stem cell-related "self-renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma. J Clin Oncol (2008) 6.41
A Cre-inducible diphtheria toxin receptor mediates cell lineage ablation after toxin administration. Nat Methods (2005) 5.59
Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis. Nat Med (2005) 4.67
IL-17A and IL-17F do not contribute vitally to autoimmune neuro-inflammation in mice. J Clin Invest (2008) 3.64
Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease-like pathology and cognitive decline. Nat Med (2012) 3.49
Interleukin-1 is responsible for acute lung immunopathology but increases survival of respiratory influenza virus infection. J Virol (2005) 3.14
Wnt5A/CaMKII signaling contributes to the inflammatory response of macrophages and is a target for the antiinflammatory action of activated protein C and interleukin-10. Arterioscler Thromb Vasc Biol (2008) 3.13
Aggravation of viral hepatitis by platelet-derived serotonin. Nat Med (2008) 3.10
An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration. Nat Neurosci (2012) 2.90
Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia. Nat Neurosci (2009) 2.85
Constitutive endocytosis of CD163 mediates hemoglobin-heme uptake and determines the noninflammatory and protective transcriptional response of macrophages to hemoglobin. Circ Res (2006) 2.68
IL-22 is expressed by Th17 cells in an IL-23-dependent fashion, but not required for the development of autoimmune encephalomyelitis. J Immunol (2007) 2.60
Rorγt+ innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in mice. J Clin Invest (2012) 2.40
Requirement of JNK2 for scavenger receptor A-mediated foam cell formation in atherogenesis. Science (2004) 2.38
Hemoglobin-driven pathophysiology is an in vivo consequence of the red blood cell storage lesion that can be attenuated in guinea pigs by haptoglobin therapy. J Clin Invest (2012) 2.19
Comparison of spectral entropy and bispectral index electroencephalography in coronary artery bypass graft surgery. J Cardiothorac Vasc Anesth (2009) 2.07
Expression and secretion of procalcitonin and calcitonin gene-related peptide by adherent monocytes and by macrophage-activated adipocytes. Crit Care Med (2004) 2.05
GM-CSF mediates autoimmunity by enhancing IL-6-dependent Th17 cell development and survival. J Exp Med (2008) 1.99
IL-21 receptor signaling is integral to the development of Th2 effector responses in vivo. Blood (2006) 1.79
Sequestration of extracellular hemoglobin within a haptoglobin complex decreases its hypertensive and oxidative effects in dogs and guinea pigs. J Clin Invest (2009) 1.77
MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status. Acta Neuropathol (2012) 1.74
Impact of synthetic and biologic disease-modifying antirheumatic drugs on antibody responses to the AS03-adjuvanted pandemic influenza vaccine: a prospective, open-label, parallel-cohort, single-center study. Arthritis Rheum (2011) 1.67
Neurological adverse events to voriconazole: evidence for therapeutic drug monitoring. Swiss Med Wkly (2006) 1.61
Hyperlipidemic myeloma: review of 53 cases. Ann Hematol (2009) 1.57
Head turns bias the brain's internal random generator. Curr Biol (2008) 1.52
Microglia inflict delayed brain injury after subarachnoid hemorrhage. Acta Neuropathol (2015) 1.51
Microglia/macrophages promote glioma progression. Glia (2010) 1.51
Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion. Nature (2003) 1.51
WHO/EORTC classification of cutaneous lymphomas 2005: histological and molecular aspects. J Cutan Pathol (2005) 1.51
Bacterial-induced protection against allergic inflammation through a multicomponent immunoregulatory mechanism. Thorax (2011) 1.49
Neuroprotective function for ramified microglia in hippocampal excitotoxicity. J Neuroinflammation (2012) 1.49
Functional impairment of microglia coincides with Beta-amyloid deposition in mice with Alzheimer-like pathology. PLoS One (2013) 1.48
Haptoglobin preserves the CD163 hemoglobin scavenger pathway by shielding hemoglobin from peroxidative modification. Blood (2009) 1.46
Starting a carotid artery stenting program is safe. Catheter Cardiovasc Interv (2008) 1.44
Soluble hemoglobin-haptoglobin scavenger receptor CD163 as a lineage-specific marker in the reactive hemophagocytic syndrome. Eur J Haematol (2005) 1.44
Microglial repopulation model reveals a robust homeostatic process for replacing CNS myeloid cells. Proc Natl Acad Sci U S A (2012) 1.43
Novel pentameric thiophene derivatives for in vitro and in vivo optical imaging of a plethora of protein aggregates in cerebral amyloidoses. ACS Chem Biol (2009) 1.42
A versatile prion replication assay in organotypic brain slices. Nat Neurosci (2007) 1.41
Subacute bilateral visual loss in methylmalonic acidemia. J Neuroophthalmol (2011) 1.41
Paracrine and autocrine mechanisms of apelin signaling govern embryonic and tumor angiogenesis. Dev Biol (2007) 1.40
Intratumoral plasmacytoid dendritic cells associate with increased survival in patients with follicular lymphoma. Leuk Lymphoma (2011) 1.39
Pathway analysis of glioblastoma tissue after preoperative treatment with the EGFR tyrosine kinase inhibitor gefitinib--a phase II trial. Mol Cancer Ther (2011) 1.39
The IL-1 receptor 1 is critical for Th2 cell type airway immune responses in a mild but not in a more severe asthma model. Eur J Immunol (2003) 1.33
Programmed death 1 protects from fatal circulatory failure during systemic virus infection of mice. J Exp Med (2012) 1.29
IL-4/IL-13-dependent alternative activation of macrophages but not microglial cells is associated with uncontrolled cerebral cryptococcosis. Am J Pathol (2009) 1.27
Absence of the prion protein homologue Doppel causes male sterility. EMBO J (2002) 1.23
Cerebral and peripheral amyloid phagocytes--an old liaison with a new twist. Neuron (2008) 1.22
Nippostrongylus brasiliensis infection leads to the development of emphysema associated with the induction of alternatively activated macrophages. Eur J Immunol (2008) 1.22
Oral prion infection requires normal numbers of Peyer's patches but not of enteric lymphocytes. Am J Pathol (2003) 1.21
Heat shock factor 1 regulates lifespan as distinct from disease onset in prion disease. Proc Natl Acad Sci U S A (2008) 1.20
Current status of xenotransplantation and prospects for clinical application. Xenotransplantation (2009) 1.15
Primary oligodendrocyte death does not elicit anti-CNS immunity. Nat Neurosci (2012) 1.15
Activating transcription factor 1 directs Mhem atheroprotective macrophages through coordinated iron handling and foam cell protection. Circ Res (2011) 1.12
Early and rapid engraftment of bone marrow-derived microglia in scrapie. J Neurosci (2006) 1.12
Humoral immune response to native eukaryotic prion protein correlates with anti-prion protection. Proc Natl Acad Sci U S A (2004) 1.10
TLR ligands act directly upon T cells to restore proliferation in the absence of protein kinase C-theta signaling and promote autoimmune myocarditis. J Immunol (2007) 1.10
Characterization of natural human anti-non-gal antibodies and their effect on activation of porcine gal-deficient endothelial cells. Transplantation (2007) 1.10
Essential role of interleukin-6 in post-stroke angiogenesis. Brain (2012) 1.09
Hemoglobin-based oxygen carriers: From mechanisms of toxicity and clearance to rational drug design. Trends Mol Med (2010) 1.09
Microglia actions in Alzheimer’s disease. Acta Neuropathol (2013) 1.09
Reactivity of human natural antibodies to endothelial cells from Galalpha(1,3)Gal-deficient pigs. Transplantation (2007) 1.09
The role of the innate immune response in autoimmune disease. J Autoimmun (2007) 1.08
The reaction of hydrogen peroxide with hemoglobin induces extensive alpha-globin crosslinking and impairs the interaction of hemoglobin with endogenous scavenger pathways. Free Radic Biol Med (2008) 1.08
Case report: Recurrence of a uterine tumor resembling ovarian sex-cord tumor. Gynecol Oncol (2009) 1.08
Haptoglobin binding stabilizes hemoglobin ferryl iron and the globin radical on tyrosine β145. Antioxid Redox Signal (2012) 1.08
Quantitative mass spectrometry defines an oxidative hotspot in hemoglobin that is specifically protected by haptoglobin. J Proteome Res (2010) 1.07
Clearance and control mechanisms of hemoglobin from cradle to grave. Antioxid Redox Signal (2010) 1.07
Hodgkin disease: diagnostic value of FDG PET/CT after first-line therapy--is biopsy of FDG-avid lesions still needed? Radiology (2007) 1.06
Diagnosis, treatment and long-term outcome of solitary fibrous tumours of the pleura. Eur J Cardiothorac Surg (2007) 1.06
Glucocorticoid treatment skews human monocyte differentiation into a hemoglobin-clearance phenotype with enhanced heme-iron recycling and antioxidant capacity. Blood (2010) 1.06
Immunosuppressive effects of streptozotocin-induced diabetes result in absolute lymphopenia and a relative increase of T regulatory cells. Diabetes (2011) 1.05
M2 polarized macrophages and giant cells contribute to myofibrosis in neuromuscular sarcoidosis. Am J Pathol (2011) 1.05
CD163-expressing monocytes constitute an endotoxin-sensitive Hb clearance compartment within the vascular system. J Leukoc Biol (2007) 1.05
No superoxide dismutase activity of cellular prion protein in vivo. Biol Chem (2003) 1.05
Prosurvival effect of DHCR24/Seladin-1 in acute and chronic responses to oxidative stress. Mol Cell Biol (2007) 1.03
Human Hp1-1 and Hp2-2 phenotype-specific haptoglobin therapeutics are both effective in vitro and in guinea pigs to attenuate hemoglobin toxicity. Antioxid Redox Signal (2013) 1.01
Disruption of Doppel prevents neurodegeneration in mice with extensive Prnp deletions. Proc Natl Acad Sci U S A (2004) 1.01
HLA-E/human beta2-microglobulin transgenic pigs: protection against xenogeneic human anti-pig natural killer cell cytotoxicity. Transplantation (2009) 1.00
Hemoglobin can attenuate hydrogen peroxide-induced oxidative stress by acting as an antioxidative peroxidase. Antioxid Redox Signal (2010) 0.99
Microglia as dynamic and essential components of the amyloid hypothesis. Neuron (2013) 0.99
Regulated expression of platelet factor 4 in human monocytes--role of PARs as a quantitatively important monocyte activation pathway. J Leukoc Biol (2005) 0.98
Immune system and peripheral nerves in propagation of prions to CNS. Br Med Bull (2003) 0.98
Anti-CD154 mAb and rapamycin induce T regulatory cell mediated tolerance in rat-to-mouse islet transplantation. PLoS One (2010) 0.97
McLeod myopathy revisited: more neurogenic and less benign. Brain (2007) 0.97
ABO-histo blood group incompatibility in hematopoietic stem cell and solid organ transplantation. Transfus Apher Sci (2006) 0.97
Immune-mediated necrotizing myopathy is characterized by a specific Th1-M1 polarized immune profile. Am J Pathol (2012) 0.96
Microglial ablation and lipopolysaccharide preconditioning affects pilocarpine-induced seizures in mice. Neurobiol Dis (2010) 0.96
Paracrine inhibition of prion propagation by anti-PrP single-chain Fv miniantibodies. J Virol (2005) 0.95
Microsatellite instability in pediatric and adult high-grade gliomas. Brain Pathol (2007) 0.94
Circumventing tolerance to the prion protein (PrP): vaccination with PrP-displaying retrovirus particles induces humoral immune responses against the native form of cellular PrP. J Virol (2005) 0.94
Modeling multiple sclerosis in laboratory animals. Semin Immunopathol (2009) 0.94
Impairment of immunoproteasome function by β5i/LMP7 subunit deficiency results in severe enterovirus myocarditis. PLoS Pathog (2011) 0.92
Evidence for age-dependent in vivo conformational rearrangement within Aβ amyloid deposits. ACS Chem Biol (2013) 0.92
HVEM signalling promotes colitis. PLoS One (2011) 0.92
Successful treatment of cold-induced neck pain and jaw claudication with revascularization of severe atherosclerotic external carotid artery stenoses. J Endovasc Ther (2007) 0.91
T regulatory cells in xenotransplantation. Xenotransplantation (2009) 0.90
Gene expression profiling and subgroup identification of oligodendrogliomas. Oncogene (2004) 0.89