Pablo Fuentes-Prior

Author PubWeight™ 37.35‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Potent phagocytic activity with impaired antigen presentation identifying lipopolysaccharide-tolerant human monocytes: demonstration in isolated monocytes from cystic fibrosis patients. J Immunol 2009 2.14
2 Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation. Nature 2003 1.92
3 Metalloproteinases shed TREM-1 ectodomain from lipopolysaccharide-stimulated human monocytes. J Immunol 2007 1.49
4 In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation. Nat Med 2011 1.38
5 Tumor cells deactivate human monocytes by up-regulating IL-1 receptor associated kinase-M expression via CD44 and TLR4. J Immunol 2005 1.34
6 Catalytic domain structures of MT-SP1/matriptase, a matrix-degrading transmembrane serine proteinase. J Biol Chem 2001 1.27
7 Mutation update of spinal muscular atrophy in Spain: molecular characterization of 745 unrelated patients and identification of four novel mutations in the SMN1 gene. Hum Genet 2008 1.17
8 Ionomycin-activated calpain triggers apoptosis. A probable role for Bcl-2 family members. J Biol Chem 2002 1.15
9 Fibrinogen substrate recognition by staphylocoagulase.(pro)thrombin complexes. J Biol Chem 2005 1.14
10 Molecular basis of protein S deficiency. Thromb Haemost 2007 1.14
11 Monocytes from cystic fibrosis patients are locked in an LPS tolerance state: down-regulation of TREM-1 as putative underlying mechanism. PLoS One 2008 1.08
12 Isolation, cloning and structural characterisation of boophilin, a multifunctional Kunitz-type proteinase inhibitor from the cattle tick. PLoS One 2008 1.06
13 Novel fluorescent prothrombin analogs as probes of staphylocoagulase-prothrombin interactions. J Biol Chem 2005 1.06
14 Tick-derived Kunitz-type inhibitors as antihemostatic factors. Insect Biochem Mol Biol 2009 1.03
15 Inflammatory responses associated with acute coronary syndrome up-regulate IRAK-M and induce endotoxin tolerance in circulating monocytes. J Endotoxin Res 2007 1.01
16 The 2.2-A crystal structure of human pro-granzyme K reveals a rigid zymogen with unusual features. J Biol Chem 2002 1.01
17 Exploring the collagen-binding site of the DDR1 tyrosine kinase receptor. J Biol Chem 2004 1.01
18 The factor V C1 domain is involved in membrane binding: identification of functionally important amino acid residues within the C1 domain of factor V using alanine scanning mutagenesis. Thromb Haemost 2004 0.98
19 The 1.4 a crystal structure of kumamolysin: a thermostable serine-carboxyl-type proteinase. Structure 2002 0.96
20 Structural basis for reduced staphylocoagulase-mediated bovine prothrombin activation. J Biol Chem 2005 0.95
21 Subcellular localization and in vivo subunit interactions of ubiquitous mu-calpain. J Biol Chem 2003 0.93
22 Leech-derived thrombin inhibitors: from structures to mechanisms to clinical applications. J Med Chem 2010 0.92
23 Unique thrombin inhibition mechanism by anophelin, an anticoagulant from the malaria vector. Proc Natl Acad Sci U S A 2012 0.88
24 Rare variants in calcium homeostasis modulator 1 (CALHM1) found in early onset Alzheimer's disease patients alter calcium homeostasis. PLoS One 2013 0.87
25 Plasminogen substrate recognition by the streptokinase-plasminogen catalytic complex is facilitated by Arg253, Lys256, and Lys257 in the streptokinase beta-domain and kringle 5 of the substrate. J Biol Chem 2009 0.86
26 Pathophysiology of interleukin-1 receptor-associated kinase-M: implications in refractory state. Curr Opin Infect Dis 2006 0.86
27 Clinical and genetic findings in five female patients with haemophilia A: Identification of a novel missense mutation, p.Phe2127Ser. Thromb Haemost 2010 0.85
28 Characterization of the residues involved in the human alpha-thrombin-haemadin complex: an exosite II-binding inhibitor. Biochemistry 2002 0.84
29 Nitric oxide induces SOCS-1 expression in human monocytes in a TNF-alpha-dependent manner. J Endotoxin Res 2006 0.82
30 Purification and in vitro refolding of maize chloroplast transglutaminase over-expressed in Escherichia coli. Biotechnol Lett 2007 0.81
31 Contribution of globular death domains and unstructured linkers to MyD88.IRAK-4 heterodimer formation: an explanation for the antagonistic activity of MyD88s. Biochem Biophys Res Commun 2009 0.80
32 Position-dependent expression of GADD45alpha in rat brain tumours. Med Oncol 2007 0.79
33 6-Methylprednisolone down-regulates IRAK-M in human and murine osteoclasts and boosts bone-resorbing activity: a putative mechanism for corticoid-induced osteoporosis. J Leukoc Biol 2007 0.79
34 Structural basis of thrombin-mediated factor V activation: the Glu666-Glu672 sequence is critical for processing at the heavy chain-B domain junction. Blood 2011 0.78
35 Structural and functional analysis of APOA5 mutations identified in patients with severe hypertriglyceridemia. J Lipid Res 2013 0.78
36 Identification of 31 novel mutations in the F8 gene in Spanish hemophilia A patients: structural analysis of 20 missense mutations suggests new intermolecular binding sites. Blood 2008 0.75
37 Confirmation of inherited protein S deficiency by PROS1 mutational screening: Identification of three novel PROS1 mutations and haplotype analysis of p.Q279X recurrence. Thromb Haemost 2008 0.75