PubRank

Matti Uusitupa

Author PubWeight™ 175.88‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Sustained reduction in the incidence of type 2 diabetes by lifestyle intervention: follow-up of the Finnish Diabetes Prevention Study. Lancet 2006 11.64
2 Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics. PLoS Genet 2008 6.22
3 The Finnish Diabetes Prevention Study (DPS): Lifestyle intervention and 3-year results on diet and physical activity. Diabetes Care 2003 5.48
4 Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet 2012 4.73
5 A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet 2012 4.37
6 Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. PLoS Med 2011 3.94
7 Lifestyle intervention with weight reduction: first-line treatment in mild obstructive sleep apnea. Am J Respir Crit Care Med 2008 3.80
8 Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet 2013 3.25
9 Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet 2013 2.92
10 Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet 2013 2.83
11 Physical activity in the prevention of type 2 diabetes: the Finnish diabetes prevention study. Diabetes 2005 2.82
12 The importance of reducing SFA to limit CHD. Br J Nutr 2011 2.60
13 Lifestyle intervention for prevention of type 2 diabetes in primary health care: one-year follow-up of the Finnish National Diabetes Prevention Program (FIN-D2D). Diabetes Care 2010 2.50
14 NAD(P)H:quinone oxidoreductase 1 NQO1*2 genotype (P187S) is a strong prognostic and predictive factor in breast cancer. Nat Genet 2008 2.18
15 Effects of n-6 PUFAs compared with SFAs on liver fat, lipoproteins, and inflammation in abdominal obesity: a randomized controlled trial. Am J Clin Nutr 2012 2.10
16 Determinants for the effectiveness of lifestyle intervention in the Finnish Diabetes Prevention Study. Diabetes Care 2008 1.95
17 Sustained improvement in mild obstructive sleep apnea after a diet- and physical activity-based lifestyle intervention: postinterventional follow-up. Am J Clin Nutr 2010 1.67
18 Dietary carbohydrate modification induces alterations in gene expression in abdominal subcutaneous adipose tissue in persons with the metabolic syndrome: the FUNGENUT Study. Am J Clin Nutr 2007 1.65
19 The prevalence of metabolic syndrome and metabolically healthy obesity in Europe: a collaborative analysis of ten large cohort studies. BMC Endocr Disord 2014 1.64
20 Serum omega-3 polyunsaturated fatty acids and risk of incident type 2 diabetes in men: the Kuopio Ischemic Heart Disease Risk Factor study. Diabetes Care 2013 1.59
21 Prevention of diabetes mellitus in subjects with impaired glucose tolerance in the Finnish Diabetes Prevention Study: results from a randomized clinical trial. J Am Soc Nephrol 2003 1.57
22 Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained. PLoS Genet 2013 1.57
23 Prevalence of the metabolic syndrome and its components: findings from a Finnish general population sample and the Diabetes Prevention Study cohort. Diabetes Care 2004 1.54
24 Effect of lifestyle intervention on the occurrence of metabolic syndrome and its components in the Finnish Diabetes Prevention Study. Diabetes Care 2008 1.51
25 The G-250A promoter polymorphism of the hepatic lipase gene predicts the conversion from impaired glucose tolerance to type 2 diabetes mellitus: the Finnish Diabetes Prevention Study. J Clin Endocrinol Metab 2004 1.50
26 Comparative evaluation of simple indices of insulin resistance. Metabolism 2004 1.42
27 Sleep duration, lifestyle intervention, and incidence of type 2 diabetes in impaired glucose tolerance: The Finnish Diabetes Prevention Study. Diabetes Care 2009 1.34
28 Triacylglycerol fatty acid composition in diet-induced weight loss in subjects with abnormal glucose metabolism--the GENOBIN study. PLoS One 2008 1.31
29 Lifestyle intervention to prevent diabetes in men and women with impaired glucose tolerance is cost-effective. Int J Technol Assess Health Care 2007 1.30
30 Association of ADIPOQ gene variants with body weight, type 2 diabetes and serum adiponectin concentrations: the Finnish Diabetes Prevention Study. BMC Med Genet 2011 1.29
31 The common variant in the FTO gene did not modify the effect of lifestyle changes on body weight: the Finnish Diabetes Prevention Study. Obesity (Silver Spring) 2009 1.26
32 Leisure-time physical activity and the metabolic syndrome in the Finnish diabetes prevention study. Diabetes Care 2010 1.22
33 The effects of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 gene on insulin sensitivity and insulin metabolism interact with size at birth. Diabetes 2002 1.18
34 An autosome-wide scan for linkage disequilibrium-based association in sporadic breast cancer cases in eastern Finland: three candidate regions found. Cancer Epidemiol Biomarkers Prev 2005 1.16
35 Importance of weight loss maintenance and risk prediction in the prevention of type 2 diabetes: analysis of European Diabetes Prevention Study RCT. PLoS One 2013 1.16
36 Effects of dietary saturated, monounsaturated, and n-3 fatty acids on blood pressure in healthy subjects. Am J Clin Nutr 2006 1.16
37 Metabolically healthy and unhealthy obesity phenotypes in the general population: the FIN-D2D Survey. BMC Public Health 2011 1.14
38 Fish oil, insulin sensitivity, insulin secretion and glucose tolerance in healthy people: is there any effect of fish oil supplementation in relation to the type of background diet and habitual dietary intake of n-6 and n-3 fatty acids? Nutr Metab Cardiovasc Dis 2006 1.14
39 Promoter polymorphisms of the TNF-alpha (G-308A) and IL-6 (C-174G) genes predict the conversion from impaired glucose tolerance to type 2 diabetes: the Finnish Diabetes Prevention Study. Diabetes 2003 1.14
40 Serum uric acid as a harbinger of metabolic outcome in subjects with impaired glucose tolerance: the Finnish Diabetes Prevention Study. Diabetes Care 2006 1.13
41 Long-term results, late complications and quality of life in a series of adjustable gastric banding. Obes Surg 2004 1.13
42 Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects. Am J Clin Nutr 2002 1.13
43 Polymorphisms of the SUR1 (ABCC8) and Kir6.2 (KCNJ11) genes predict the conversion from impaired glucose tolerance to type 2 diabetes. The Finnish Diabetes Prevention Study. J Clin Endocrinol Metab 2004 1.10
44 Whole grain products, fish and bilberries alter glucose and lipid metabolism in a randomized, controlled trial: the Sysdimet study. PLoS One 2011 1.08
45 Association of ADIPOR2 gene variants with cardiovascular disease and type 2 diabetes risk in individuals with impaired glucose tolerance: the Finnish Diabetes Prevention Study. Cardiovasc Diabetol 2011 1.07
46 Gene expression of peripheral blood mononuclear cells as a tool in dietary intervention studies: What do we know so far? Mol Nutr Food Res 2012 1.06
47 Effects of dietary saturated, monounsaturated and n-3 fatty acids on fasting lipoproteins, LDL size and post-prandial lipid metabolism in healthy subjects. Atherosclerosis 2003 1.06
48 Cardiometabolic profile of people screened for high risk of type 2 diabetes in a national diabetes prevention programme (FIN-D2D). Prim Care Diabetes 2010 1.02
49 Dietary (n-3) fatty acids reduce plasma F2-isoprostanes but not prostaglandin F2alpha in healthy humans. J Nutr 2006 1.01
50 The activation of the inflammatory cytokines in overweight patients with mild obstructive sleep apnoea. J Sleep Res 2009 0.99
51 Weight reduction and increased physical activity to prevent the progression of obstructive sleep apnea: A 4-year observational postintervention follow-up of a randomized clinical trial. [corrected]. JAMA Intern Med 2013 0.99
52 Cholesterol absorption decreases after Roux-en-Y gastric bypass but not after gastric banding. Metabolism 2009 0.99
53 Polymorphisms in the SLC2A2 (GLUT2) gene are associated with the conversion from impaired glucose tolerance to type 2 diabetes: the Finnish Diabetes Prevention Study. Diabetes 2005 0.98
54 Association of erythrocyte membrane fatty acids with changes in glycemia and risk of type 2 diabetes. Am J Clin Nutr 2013 0.98
55 Inflammation markers are modulated by responses to diets differing in postprandial insulin responses in individuals with the metabolic syndrome. Am J Clin Nutr 2008 0.97
56 Variation in the UCP2 and UCP3 genes associates with abdominal obesity and serum lipids: the Finnish Diabetes Prevention Study. BMC Med Genet 2009 0.96
57 Systemic immune mediators and lifestyle changes in the prevention of type 2 diabetes: results from the Finnish Diabetes Prevention Study. Diabetes 2006 0.96
58 Primary vitamin D target genes allow a categorization of possible benefits of vitamin D₃ supplementation. PLoS One 2013 0.95
59 Leukocyte telomere length in the Finnish Diabetes Prevention Study. PLoS One 2012 0.95
60 Association of the fat mass and obesity-associated (FTO) gene variant (rs9939609) with dietary intake in the Finnish Diabetes Prevention Study. Br J Nutr 2012 0.95
61 Fatty fish intake decreases lipids related to inflammation and insulin signaling--a lipidomics approach. PLoS One 2009 0.95
62 Obesity and obstructive sleep apnea--clinical significance of weight loss. Sleep Med Rev 2012 0.95
63 Socioeconomic position and effectiveness of lifestyle intervention in prevention of type 2 diabetes: one-year follow-up of the FIN-D2D project. Scand J Public Health 2011 0.93
64 Insulin secretion and its determinants in the progression of impaired glucose tolerance to type 2 diabetes in impaired glucose-tolerant individuals: the Finnish Diabetes Prevention Study. Diabetes Care 2011 0.93
65 Orally administered betaine has an acute and dose-dependent effect on serum betaine and plasma homocysteine concentrations in healthy humans. J Nutr 2006 0.92
66 Vitamin D receptor gene polymorphism as an important modifier of positive family history related breast cancer risk. Pharmacogenetics 2004 0.92
67 Effect of weight loss on cytokine messenger RNA expression in peripheral blood mononuclear cells of obese subjects with the metabolic syndrome. Metabolism 2008 0.91
68 The effect of intensified diet counseling on the diet of hypertensive subjects in primary health care: a 2-year open randomized controlled trial of lifestyle intervention against hypertension in eastern Finland. Prev Med 2003 0.91
69 Increase in physical activity and cardiometabolic risk profile change during lifestyle intervention in primary healthcare: 1-year follow-up study among individuals at high risk for type 2 diabetes. BMJ Open 2011 0.91
70 Refinement of the 22q12-q13 breast cancer--associated region: evidence of TMPRSS6 as a candidate gene in an eastern Finnish population. Clin Cancer Res 2006 0.90
71 Costs of a self-selected, health-promoting diet among the participants of the Finnish Diabetes Prevention Study. Diabetes Care 2007 0.88
72 Glycerol and fatty acids in serum predict the development of hyperglycemia and type 2 diabetes in Finnish men. Diabetes Care 2013 0.88
73 Gene expression of FTO in human subcutaneous adipose tissue, peripheral blood mononuclear cells and adipocyte cell line. J Nutrigenet Nutrigenomics 2010 0.87
74 The effect of fatty or lean fish intake on inflammatory gene expression in peripheral blood mononuclear cells of patients with coronary heart disease. Eur J Nutr 2009 0.87
75 Epidemiology and treatment of the metabolic syndrome. Ann Med 2004 0.87
76 Combined COMT and GST genotypes and hormone replacement therapy associated breast cancer risk. Pharmacogenetics 2002 0.87
77 SNPs in PPARG associate with type 2 diabetes and interact with physical activity. Med Sci Sports Exerc 2008 0.87
78 A deletion in the alpha2B-adrenergic receptor gene and autonomic nervous function in central obesity. Obes Res 2003 0.87
79 Ghrelin in diabetes and metabolic syndrome. Int J Pept 2010 0.87
80 Socio-economic differences in dysglycemia and lifestyle-related risk factors in the Finnish middle-aged population. Eur J Public Health 2010 0.86
81 Interaction of single nucleotide polymorphisms in ADRB2, ADRB3, TNF, IL6, IGF1R, LIPC, LEPR, and GHRL with physical activity on the risk of type 2 diabetes mellitus and changes in characteristics of the metabolic syndrome: The Finnish Diabetes Prevention Study. Metabolism 2008 0.86
82 NAT2 slow acetylator genotype as an important modifier of breast cancer risk. Int J Cancer 2005 0.86
83 Effects of rye and whole wheat versus refined cereal foods on metabolic risk factors: a randomised controlled two-centre intervention study. Clin Nutr 2013 0.86
84 XRCC1 and XPD genetic polymorphisms, smoking and breast cancer risk in a Finnish case-control study. Breast Cancer Res 2005 0.86
85 Physical activity, diet, and incident diabetes in relation to an ADRA2B polymorphism. Med Sci Sports Exerc 2007 0.85
86 Educational attainment and effectiveness of lifestyle intervention in the Finnish Diabetes Prevention Study. Diabetes Res Clin Pract 2009 0.84
87 No observed local immunological response at cell level after five years of oats in adult coeliac disease. Scand J Gastroenterol 2007 0.84
88 DNA methylation in obesity and type 2 diabetes. Ann Med 2014 0.84
89 Lifestyle intervention, diabetes, and cardiovascular disease. Lancet 2008 0.84
90 Expression of ghrelin gene in peripheral blood mononuclear cells and plasma ghrelin concentrations in patients with metabolic syndrome. Eur J Endocrinol 2008 0.84
91 Genetic predisposition to obesity and lifestyle factors--the combined analyses of twenty-six known BMI- and fourteen known waist:hip ratio (WHR)-associated variants in the Finnish Diabetes Prevention Study. Br J Nutr 2013 0.84
92 Adiponectin receptor 1 gene (ADIPOR1) variant is associated with advanced age-related macular degeneration in Finnish population. Neurosci Lett 2012 0.84
93 History of medically treated diabetes and risk of Alzheimer disease in a nationwide case-control study. Diabetes Care 2013 0.83
94 CYP1A1 and CYP1B1 genetic polymorphisms, smoking and breast cancer risk in a Finnish Caucasian population. Breast Cancer Res Treat 2006 0.83
95 Tenomodulin is associated with obesity and diabetes risk: the Finnish diabetes prevention study. Obesity (Silver Spring) 2007 0.82
96 Aldose reductase gene polymorphisms and peripheral nerve function in patients with type 2 diabetes. Diabetes Care 2004 0.82
97 Dietary fat in relation to erythrocyte fatty acid composition in men. Lipids 2013 0.82
98 Sulfotransferase 1A1 genotype as a potential modifier of breast cancer risk among premenopausal women. Pharmacogenet Genomics 2005 0.82
99 Variations in the ghrelin receptor gene associate with obesity and glucose metabolism in individuals with impaired glucose tolerance. PLoS One 2008 0.82
100 Lifestyles matter in the prevention of type 2 diabetes. Diabetes Care 2002 0.81
101 Do statins interfere with lifestyle intervention in the prevention of diabetes in primary healthcare? One-year follow-up of the FIN-D2D project. BMJ Open 2012 0.81
102 Anthropometry, bioelectrical impedance and dual-energy X-ray absorptiometry in the assessment of body composition in elderly Finnish women. Clin Physiol Funct Imaging 2002 0.81
103 ADAMTS9 locus associates with increased risk of wet AMD. Acta Ophthalmol 2014 0.81
104 Population-level effects of the national diabetes prevention programme (FIN-D2D) on the body weight, the waist circumference, and the prevalence of obesity. BMC Public Health 2011 0.81
105 Serum adipokines are associated with cholesterol metabolism in the metabolic syndrome. Clin Chim Acta 2007 0.81
106 Long-term repeatability of measures of early insulin secretion derived from an intravenous glucose tolerance test and conversion from impaired glucose tolerance to diabetes. Ann Med 2008 0.80
107 Tenomodulin gene and obesity-related phenotypes. Ann Med 2010 0.79
108 Interactions between peroxisome proliferator-activated receptor-gamma 2 gene polymorphisms and size at birth on blood pressure and the use of antihypertensive medication. J Hypertens 2004 0.79
109 Short-term LDL cholesterol-lowering efficacy of plant stanol esters. BMC Cardiovasc Disord 2002 0.79
110 Predictors of success of a lifestyle intervention in relation to weight loss and improvement in glucose tolerance among individuals at high risk for type 2 diabetes: the FIN-D2D project. J Prim Care Community Health 2012 0.79
111 The genetic variation of the tenomodulin gene (TNMD) is associated with serum levels of systemic immune mediators--the Finnish Diabetes Prevention Study. Genet Med 2008 0.78
112 Downregulation of CPPED1 expression improves glucose metabolism in vitro in adipocytes. Diabetes 2013 0.78
113 Plasma alkylresorcinols reflect important whole-grain components of a healthy Nordic diet. J Nutr 2013 0.78
114 Interactions between peroxisome proliferator-activated receptor gene polymorphism and birth length influence risk for type 2 diabetes. Diabetes Care 2003 0.78
115 Effects of a healthy Nordic diet on plasma 25-hydroxyvitamin D concentration in subjects with metabolic syndrome: a randomized, [corrected] controlled trial (SYSDIET). Eur J Nutr 2014 0.77
116 The Leu7Pro polymorphism of the neuropeptide Y gene regulates free fatty acid metabolism. Metabolism 2003 0.77
117 Long-term effects of placental growth on overweight and body composition. Int J Pediatr 2012 0.77
118 Treatment improves serotonin transporter binding and reduces binge eating. Psychopharmacology (Berl) 2003 0.77
119 Participation, socioeconomic status and group or individual counselling intervention in individuals at high risk for type 2 diabetes: one-year follow-up study of the FIN-D2D-project. Prim Care Diabetes 2012 0.77
120 Lifestyle intervention in prevention of type 2 diabetes in women with a history of gestational diabetes mellitus: one-year results of the FIN-D2D project. J Womens Health (Larchmt) 2014 0.77
121 Single nucleotide polymorphisms of the tenomodulin gene (TNMD) in age-related macular degeneration. Mol Vis 2009 0.76
122 Iris transluminance in type 2 diabetes. Acta Ophthalmol Scand 2002 0.75
123 Tenomodulin variants, APOE and Alzheimer's disease in a Finnish case-control cohort. Neurobiol Aging 2009 0.75
124 Changes in vitamin D target gene expression in adipose tissue monitor the vitamin D response of human individuals. Mol Nutr Food Res 2014 0.75
125 Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet 2016 0.75
126 Prolonged corrected QT interval is associated with acute and chronic hyperinsulinemia in nondiabetic subjects. Diabetes Care 2003 0.75
127 Destiny in your own hands--does a positive family history matter in the prevention of type 2 diabetes? Prim Care Diabetes 2011 0.75
128 Quality of diet is important for the prevention of cardiovascular disease. J Intern Med 2010 0.75
129 [Inherited combined hyperlipidemia (FKH)--revealing the genetic etiology is getting closer]. Duodecim 2004 0.75
130 [Nutrigenomics-key for identification of molecular effects of nutritional factors]. Duodecim 2005 0.75
131 [Not Available]. Duodecim 2007 0.75
132 [Not Available]. Duodecim 2006 0.75
133 [N-3 fatty acids give protection against sudden death in patients with coronary artery disease]. Duodecim 2002 0.75
134 [Conflicts of interest in financing medical research]. Duodecim 2003 0.75
135 Subtle hyperproinsulinaemia characterises the defective insulin secretory capacity in offspring of glutamic acid decarboxylase antibody-positive patients with latent autoimmune diabetes mellitus in adults. Eur J Endocrinol 2005 0.75
136 [Update on current care guidelines. Celiac disease]. Duodecim 2005 0.75
137 [Liposuction as treatment of diabetes--is it an effective treatment?]. Duodecim 2004 0.75
138 [Highlights of Finnish nutrition research]. Duodecim 2015 0.75
139 [Brain imaging in eating disorders and obesity reseach]. Duodecim 2003 0.75
140 Assessment of body composition in subjects with metabolic syndrome comparing single-frequency bioelectrical impedance analysis and bioelectrical spectroscopy. Metab Syndr Relat Disord 2014 0.75