| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Novel receptor partners and function of receptor activity-modifying proteins.
|
J Biol Chem
|
2002
|
2.14
|
|
2
|
Pharmacology and functions of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide: IUPHAR review 1.
|
Br J Pharmacol
|
2012
|
1.64
|
|
3
|
Identification of restricted subsets of mature microRNA abnormally expressed in inactive colonic mucosa of patients with inflammatory bowel disease.
|
PLoS One
|
2010
|
1.54
|
|
4
|
Protease-activated receptor 2 in colon cancer: trypsin-induced MAPK phosphorylation and cell proliferation are mediated by epidermal growth factor receptor transactivation.
|
J Biol Chem
|
2004
|
1.53
|
|
5
|
Class-B GPCR activation: is ligand helix-capping the key?
|
Trends Biochem Sci
|
2008
|
1.29
|
|
6
|
Aberrant expression and activation of the thrombin receptor protease-activated receptor-1 induces cell proliferation and motility in human colon cancer cells.
|
Am J Pathol
|
2003
|
1.21
|
|
7
|
Activation of proteinase-activated receptor 1 promotes human colon cancer cell proliferation through epidermal growth factor receptor transactivation.
|
Mol Cancer Res
|
2004
|
1.10
|
|
8
|
Orexins acting at native OX(1) receptor in colon cancer and neuroblastoma cells or at recombinant OX(1) receptor suppress cell growth by inducing apoptosis.
|
J Biol Chem
|
2004
|
1.02
|
|
9
|
Molecular and conformational determinants of pituitary adenylate cyclase-activating polypeptide (PACAP) for activation of the PAC1 receptor.
|
J Med Chem
|
2009
|
0.99
|
|
10
|
Peptide agonist docking in the N-terminal ectodomain of a class II G protein-coupled receptor, the VPAC1 receptor. Photoaffinity, NMR, and molecular modeling.
|
J Biol Chem
|
2006
|
0.99
|
|
11
|
VPAC receptors: structure, molecular pharmacology and interaction with accessory proteins.
|
Br J Pharmacol
|
2012
|
0.99
|
|
12
|
Identification of cytoplasmic domains of hVPAC1 receptor required for activation of adenylyl cyclase. Crucial role of two charged amino acids strictly conserved in class II G protein-coupled receptors.
|
J Biol Chem
|
2003
|
0.95
|
|
13
|
The vasoactive intestinal peptide (VIP) alpha-Helix up to C terminus interacts with the N-terminal ectodomain of the human VIP/Pituitary adenylate cyclase-activating peptide 1 receptor: photoaffinity, molecular modeling, and dynamics.
|
Mol Endocrinol
|
2007
|
0.95
|
|
14
|
Aberrant expression of proteinase-activated receptor 4 promotes colon cancer cell proliferation through a persistent signaling that involves Src and ErbB-2 kinase.
|
Int J Cancer
|
2009
|
0.92
|
|
15
|
Spatial proximity between the VPAC1 receptor and the amino terminus of agonist and antagonist peptides reveals distinct sites of interaction.
|
FASEB J
|
2012
|
0.91
|
|
16
|
A hallmark of immunoreceptor, the tyrosine-based inhibitory motif ITIM, is present in the G protein-coupled receptor OX1R for orexins and drives apoptosis: a novel mechanism.
|
FASEB J
|
2008
|
0.91
|
|
17
|
Novel stable PACAP analogs with potent activity towards the PAC1 receptor.
|
Peptides
|
2008
|
0.91
|
|
18
|
The family B1 GPCR: structural aspects and interaction with accessory proteins.
|
Curr Drug Targets
|
2012
|
0.90
|
|
19
|
Orexin-induced apoptosis: the key role of the seven-transmembrane domain orexin type 2 receptor.
|
Endocrinology
|
2006
|
0.90
|
|
20
|
Presence of a N-terminal signal peptide in class II G protein-coupled receptors: crucial role for expression of the human VPAC1 receptor.
|
Regul Pept
|
2004
|
0.89
|
|
21
|
Trypsin is produced by and activates protease-activated receptor-2 in human cancer colon cells: evidence for new autocrine loop.
|
Life Sci
|
2002
|
0.88
|
|
22
|
Orexins control intestinal glucose transport by distinct neuronal, endocrine, and direct epithelial pathways.
|
Diabetes
|
2007
|
0.88
|
|
23
|
Discovery of a functional immunoreceptor tyrosine-based switch motif in a 7-transmembrane-spanning receptor: role in the orexin receptor OX1R-driven apoptosis.
|
FASEB J
|
2009
|
0.88
|
|
24
|
Aberrant expression of OX1 receptors for orexins in colon cancers and liver metastases: an openable gate to apoptosis.
|
Cancer Res
|
2011
|
0.87
|
|
25
|
Serine 447 in the carboxyl tail of human VPAC1 receptor is crucial for agonist-induced desensitization but not internalization of the receptor.
|
Mol Pharmacol
|
2003
|
0.84
|
|
26
|
The N-terminal parts of VIP and antagonist PG97-269 physically interact with different regions of the human VPAC1 receptor.
|
J Mol Neurosci
|
2008
|
0.83
|
|
27
|
Photoaffinity labeling demonstrates physical contact between vasoactive intestinal peptide and the N-terminal ectodomain of the human VPAC1 receptor.
|
J Biol Chem
|
2003
|
0.83
|
|
28
|
Diffuse pharmacophoric domains of vasoactive intestinal peptide (VIP) and further insights into the interaction of VIP with the N-terminal ectodomain of human VPAC1 receptor by photoaffinity labeling with [Bpa6]-VIP.
|
J Biol Chem
|
2004
|
0.82
|
|
29
|
VIP blockade leads to microcephaly in mice via disruption of Mcph1-Chk1 signaling.
|
J Clin Invest
|
2011
|
0.81
|
|
30
|
Human VPAC1 receptor selectivity filter. Identification of a critical domain for restricting secretin binding.
|
J Biol Chem
|
2002
|
0.80
|
|
31
|
Biological and structural analysis of truncated analogs of PACAP27.
|
J Mol Neurosci
|
2008
|
0.78
|
|
32
|
PACAP prevents toxicity induced by cisplatin in rat and primate neurons but not in proliferating ovary cells: involvement of the mitochondrial apoptotic pathway.
|
Neurobiol Dis
|
2008
|
0.78
|
|
33
|
PAR-2 activation increases human intestinal mucin secretion through EGFR transactivation.
|
Biochem Biophys Res Commun
|
2007
|
0.78
|
|
34
|
Involvement of VIP and PACAP in neonatal brain lesions generated by a combined excitotoxic/inflammatory challenge.
|
Peptides
|
2007
|
0.77
|
|
35
|
The human VPAC1 receptor: identification of the N-terminal ectodomain as a major VIP-binding site by photoaffinity labeling and 3D modeling.
|
Ann N Y Acad Sci
|
2006
|
0.77
|
|
36
|
Production and purification of large quantities of the functional N-terminal ectodomain of human VPAC1 receptor.
|
J Mol Neurosci
|
2008
|
0.76
|
|
37
|
[How to turn a silent proapoptotic gene in a potent antitumoral target in colorectal cancer].
|
Med Sci (Paris)
|
2012
|
0.75
|
|
38
|
Characterization of the new photoaffinity probe (Bz2-K24)-VIP.
|
Ann N Y Acad Sci
|
2006
|
0.75
|
|
39
|
[MicroRNAs and intestinal pathophysiology].
|
Med Sci (Paris)
|
2007
|
0.75
|
|
40
|
Expression and GTP sensitivity of peptide histidine isoleucine high-affinity-binding sites in rat.
|
Ann N Y Acad Sci
|
2006
|
0.75
|
|
41
|
Strategies for studying the ligand binding site of GPCRs: photoaffinity labeling of the VPAC1 receptor, a prototype of class B GPCRs.
|
Methods Enzymol
|
2013
|
0.75
|