Published in Nihon Ronen Igakkai Zasshi on November 01, 2007
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2014). Hypertens Res (2014) 4.83
Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians. Nat Genet (2011) 4.04
Meta-analysis identifies common variants associated with body mass index in east Asians. Nat Genet (2012) 2.70
Deep cerebral microbleeds are negatively associated with HDL-C in elderly first-time ischemic stroke patients. J Neurol Sci (2013) 1.97
An association between decreased estimated glomerular filtration rate and arterial stiffness. Intern Med (2008) 1.75
Identification of hypertension-susceptibility genes and pathways by a systemic multiple candidate gene approach: the millennium genome project for hypertension. Hypertens Res (2008) 1.72
Association of central systolic blood pressure with intracerebral small vessel disease in Japanese. Am J Hypertens (2010) 1.59
Effect of acute and long-term aerobic exercise on arterial stiffness in the elderly. Hypertens Res (2007) 1.55
The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between beta-amyloid production and tau phosphorylation in Alzheimer disease. Hum Mol Genet (2006) 1.50
Cross-sectional characterization of all classes of antihypertensives in terms of central blood pressure in Japanese hypertensive patients. Am J Hypertens (2009) 1.50
Postprandial hypotension as a risk marker for asymptomatic lacunar infarction. J Hypertens (2014) 1.50
Accumulation of common polymorphisms is associated with development of hypertension: a 12-year follow-up from the Ohasama study. Hypertens Res (2009) 1.47
Soluble Fas ligand and atherosclerosis in hypertensive patients. J Hypertens (2002) 1.45
High-density association study and nomination of susceptibility genes for hypertension in the Japanese National Project. Hum Mol Genet (2007) 1.44
Improvement of insulin resistance by troglitazone ameliorates cardiac sympathetic nervous dysfunction in patients with essential hypertension. J Hypertens (2004) 1.42
Angiotensin-converting enzyme inhibitors as a new therapy for atrial fibrillation? Controversy. Am Heart J (2005) 1.37
Plasma resistin, associated with single nucleotide polymorphism -420, is correlated with insulin resistance, lower HDL cholesterol, and high-sensitivity C-reactive protein in the Japanese general population. Diabetes Care (2007) 1.34
Replication study of candidate genes associated with type 2 diabetes based on genome-wide screening. Diabetes (2008) 1.33
Arterial stiffness is associated with low thigh muscle mass in middle-aged to elderly men. Atherosclerosis (2010) 1.31
Common variants in the ATP2B1 gene are associated with susceptibility to hypertension: the Japanese Millennium Genome Project. Hypertension (2010) 1.26
Radial augmentation index: a useful and easily obtainable parameter for vascular aging. Am J Hypertens (2005) 1.12
A genome-wide association study of hypertension-related phenotypes in a Japanese population. Circ J (2010) 1.10
Diagnostic criteria for Werner syndrome based on Japanese nationwide epidemiological survey. Geriatr Gerontol Int (2012) 1.08
The GCKR rs780094 polymorphism is associated with susceptibility of type 2 diabetes, reduced fasting plasma glucose levels, increased triglycerides levels and lower HOMA-IR in Japanese population. J Hum Genet (2010) 1.08
Resistin SNP-420 determines its monocyte mRNA and serum levels inducing type 2 diabetes. Biochem Biophys Res Commun (2005) 1.07
Effect of genetic polymorphism of OATP-C (SLCO1B1) on lipid-lowering response to HMG-CoA reductase inhibitors. Drug Metab Pharmacokinet (2004) 1.07
MTHFR gene polymorphism as a risk factor for silent brain infarcts and white matter lesions in the Japanese general population: The NILS-LSA Study. Stroke (2003) 1.05
Genetic basis of inter-individual variability in the effects of exercise on the alleviation of lifestyle-related diseases. J Physiol (2009) 1.02
Abdominal fat, adipose-derived hormones and mild cognitive impairment: the J-SHIPP study. Dement Geriatr Cogn Disord (2010) 1.02
TRIC-A channels in vascular smooth muscle contribute to blood pressure maintenance. Cell Metab (2011) 1.02
An intronic variable number of tandem repeat polymorphisms of the cold-induced autoinflammatory syndrome 1 (CIAS1) gene modifies gene expression and is associated with essential hypertension. Eur J Hum Genet (2006) 1.02
Association of endothelin-1 gene variant with hypertension. Hypertension (2003) 1.02
High-sensitivity C-reactive protein and gamma-glutamyl transferase levels are synergistically associated with metabolic syndrome in community-dwelling persons. Cardiovasc Diabetol (2010) 1.02
No association between INSIG2 Gene rs7566605 polymorphism and being overweight in Japanese population. Obesity (Silver Spring) (2008) 1.01
Screening for TARDBP mutations in Japanese familial amyotrophic lateral sclerosis. J Neurol Sci (2009) 1.01
Mice lacking hypertension candidate gene ATP2B1 in vascular smooth muscle cells show significant blood pressure elevation. Hypertension (2012) 0.98
Silent cerebral microbleeds associated with arterial stiffness in an apparently healthy subject. Hypertens Res (2009) 0.95
Reduced high-molecular-weight adiponectin and elevated high-sensitivity C-reactive protein are synergistic risk factors for metabolic syndrome in a large-scale middle-aged to elderly population: the Shimanami Health Promoting Program Study. J Clin Endocrinol Metab (2007) 0.93
Genetic variation in CDH13 is associated with lower plasma adiponectin levels but greater adiponectin sensitivity in East Asian populations. Diabetes (2013) 0.93
Vasopressin V1a receptor polymorphism and interval walking training effects in middle-aged and older people. Hypertension (2010) 0.93
Positive natural selection of TRIB2, a novel gene that influences visceral fat accumulation, in East Asia. Hum Genet (2012) 0.93
Identification of hippocampus-related candidate genes for Alzheimer's disease. Ann Neurol (2005) 0.93
Reelin signals survival through Src-family kinases that inactivate BAD activity. J Neurochem (2007) 0.93
Variations in the BDNF gene in autopsy-confirmed Alzheimer's disease and dementia with Lewy bodies in Japan. Dement Geriatr Cogn Disord (2006) 0.92
Relationships between lipid profiles and metabolic syndrome, insulin resistance and serum high molecular adiponectin in Japanese community-dwelling adults. Lipids Health Dis (2011) 0.92
Alanine aminotransferase/aspartate aminotransferase ratio is the best surrogate marker for insulin resistance in non-obese Japanese adults. Cardiovasc Diabetol (2012) 0.92
Polymorphism of the monocyte chemoattractant protein (MCP-1) gene is associated with the plasma level of MCP-1 but not with carotid intima-media thickness. Hypertens Res (2003) 0.91
A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2. Hum Mol Genet (2013) 0.91
Hypotension associated with prone body position: a possible overlooked postural hypotension. Hypertens Res (2005) 0.91
Mutation of the follicle-stimulating hormone receptor gene 5'-untranslated region associated with female hypertension. Hypertension (2006) 0.91
Serum uric acid is more strongly associated with impaired fasting glucose in women than in men from a community-dwelling population. PLoS One (2013) 0.89
Hematological parameters are associated with metabolic syndrome in Japanese community-dwelling persons. Endocrine (2013) 0.89
Methyl-CpG binding protein 2 gene (MECP2) variations in Japanese patients with Rett syndrome: pathological mutations and polymorphisms. Brain Dev (2005) 0.89
Frequency of the G/G genotype of resistin single nucleotide polymorphism at -420 appears to be increased in younger-onset type 2 diabetes. Diabetes (2007) 0.88
An association between metabolic syndrome and the estimated glomerular filtration rate. Intern Med (2008) 0.87
NFkappaB regulates plasma apolipoprotein A-I and high density lipoprotein cholesterol through inhibition of peroxisome proliferator-activated receptor alpha. J Biol Chem (2003) 0.87
A at single nucleotide polymorphism-358 is required for G at -420 to confer the highest plasma resistin in the general Japanese population. PLoS One (2010) 0.87
Association of polymorphisms of paraoxonase 1 and 2 genes, alone or in combination, with bone mineral density in community-dwelling Japanese. J Hum Genet (2003) 0.87
Association of four genetic loci with uric acid levels and reduced renal function: the J-SHIPP Suita study. Am J Nephrol (2010) 0.87
Microalbuminuria and arterial stiffness in a general population: the Shimanami Health Promoting Program (J-SHIPP) study. Hypertens Res (2004) 0.87
Carotid atherosclerosis in normal-weight metabolic syndrome. Intern Med (2007) 0.87
High prevalence of prehypertension is associated with the increased body mass index in community-dwelling Japanese. Tohoku J Exp Med (2008) 0.87
Association between fasting plasma glucose and high-sensitivity C-reactive protein: gender differences in a Japanese community-dwelling population. Cardiovasc Diabetol (2011) 0.87