| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Profiling critical cancer gene mutations in clinical tumor samples.
|
PLoS One
|
2009
|
5.63
|
|
2
|
Identification of fibroblast heterogeneity in the tumor microenvironment.
|
Cancer Biol Ther
|
2006
|
4.20
|
|
3
|
A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors.
|
Proc Natl Acad Sci U S A
|
2003
|
3.72
|
|
4
|
Platelets actively sequester angiogenesis regulators.
|
Blood
|
2008
|
2.47
|
|
5
|
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma.
|
Nat Genet
|
2013
|
2.42
|
|
6
|
Clinical trial of a farnesyltransferase inhibitor in children with Hutchinson-Gilford progeria syndrome.
|
Proc Natl Acad Sci U S A
|
2012
|
2.04
|
|
7
|
Intensive multimodality treatment for children with newly diagnosed CNS atypical teratoid rhabdoid tumor.
|
J Clin Oncol
|
2008
|
1.92
|
|
8
|
Critical oncogenic mutations in newly diagnosed pediatric diffuse intrinsic pontine glioma.
|
Pediatr Blood Cancer
|
2011
|
1.91
|
|
9
|
Phase I trial of imatinib in children with newly diagnosed brainstem and recurrent malignant gliomas: a Pediatric Brain Tumor Consortium report.
|
Neuro Oncol
|
2007
|
1.84
|
|
10
|
PPARalpha agonist fenofibrate suppresses tumor growth through direct and indirect angiogenesis inhibition.
|
Proc Natl Acad Sci U S A
|
2008
|
1.80
|
|
11
|
Clinicopathologic study of glioblastoma in children with neurofibromatosis type 1.
|
Pediatr Blood Cancer
|
2010
|
1.76
|
|
12
|
Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice.
|
J Clin Invest
|
2011
|
1.74
|
|
13
|
Disease progression in Hutchinson-Gilford progeria syndrome: impact on growth and development.
|
Pediatrics
|
2007
|
1.67
|
|
14
|
Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis.
|
Proc Natl Acad Sci U S A
|
2013
|
1.66
|
|
15
|
Phase 2 randomized, flexible crossover, double-blinded, placebo-controlled trial of the farnesyltransferase inhibitor tipifarnib in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas.
|
Neuro Oncol
|
2014
|
1.66
|
|
16
|
BET bromodomain inhibition of MYC-amplified medulloblastoma.
|
Clin Cancer Res
|
2013
|
1.64
|
|
17
|
Neurologic features of Hutchinson-Gilford progeria syndrome after lonafarnib treatment.
|
Neurology
|
2013
|
1.62
|
|
18
|
The rationale for nonsteroidal anti-inflammatory drug therapy for inflammatory myofibroblastic tumors: a Children's Oncology Group study.
|
J Pediatr Surg
|
2005
|
1.39
|
|
19
|
Proceedings from the 2009 genetic syndromes of the Ras/MAPK pathway: From bedside to bench and back.
|
Am J Med Genet A
|
2010
|
1.36
|
|
20
|
Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1.
|
Proc Natl Acad Sci U S A
|
2013
|
1.33
|
|
21
|
Phase I clinical trial of cilengitide in children with refractory brain tumors: Pediatric Brain Tumor Consortium Study PBTC-012.
|
J Clin Oncol
|
2008
|
1.33
|
|
22
|
PPARgamma as a therapeutic target for tumor angiogenesis and metastasis.
|
Cancer Biol Ther
|
2005
|
1.28
|
|
23
|
PPARalpha deficiency in inflammatory cells suppresses tumor growth.
|
PLoS One
|
2007
|
1.24
|
|
24
|
Efficacy of the HSP90 inhibitor 17-AAG in human glioma cell lines and tumorigenic glioma stem cells.
|
Neuro Oncol
|
2008
|
1.22
|
|
25
|
ZD6474, a novel tyrosine kinase inhibitor of vascular endothelial growth factor receptor and epidermal growth factor receptor, inhibits tumor growth of multiple nervous system tumors.
|
Clin Cancer Res
|
2005
|
1.16
|
|
26
|
Mechanisms of premature vascular aging in children with Hutchinson-Gilford progeria syndrome.
|
Hypertension
|
2011
|
1.16
|
|
27
|
Phase II trial of temsirolimus in children with high-grade glioma, neuroblastoma and rhabdomyosarcoma.
|
Eur J Cancer
|
2011
|
1.15
|
|
28
|
Specific detection of methionine 27 mutation in histone 3 variants (H3K27M) in fixed tissue from high-grade astrocytomas.
|
Acta Neuropathol
|
2014
|
1.15
|
|
29
|
Anti-apoptosis mechanisms in malignant gliomas.
|
J Clin Oncol
|
2008
|
1.14
|
|
30
|
Continuous remission of newly diagnosed and relapsed central nervous system atypical teratoid/rhabdoid tumor.
|
J Neurooncol
|
2005
|
1.13
|
|
31
|
Diffuse intrinsic pontine glioma: a reassessment.
|
J Neurooncol
|
2014
|
1.12
|
|
32
|
Detection of KIAA1549-BRAF fusion transcripts in formalin-fixed paraffin-embedded pediatric low-grade gliomas.
|
J Mol Diagn
|
2011
|
1.11
|
|
33
|
A phase I and biology study of gefitinib and radiation in children with newly diagnosed brain stem gliomas or supratentorial malignant gliomas.
|
Eur J Cancer
|
2010
|
1.09
|
|
34
|
Hutchinson-Gilford progeria is a skeletal dysplasia.
|
J Bone Miner Res
|
2011
|
1.09
|
|
35
|
Epoxyeicosanoids promote organ and tissue regeneration.
|
Proc Natl Acad Sci U S A
|
2013
|
1.08
|
|
36
|
Basement membrane derived fibulin-1 and fibulin-5 function as angiogenesis inhibitors and suppress tumor growth.
|
Exp Biol Med (Maywood)
|
2008
|
1.04
|
|
37
|
Expression of the neuron-specific protein CHD5 is an independent marker of outcome in neuroblastoma.
|
Mol Cancer
|
2010
|
1.03
|
|
38
|
Perfusion MRI of U87 brain tumors in a mouse model.
|
Magn Reson Med
|
2004
|
1.03
|
|
39
|
DNA fragmentation simulation method (FSM) and fragment size matching improve aCGH performance of FFPE tissues.
|
PLoS One
|
2012
|
1.02
|
|
40
|
A phase II trial of a multi-agent oral antiangiogenic (metronomic) regimen in children with recurrent or progressive cancer.
|
Pediatr Blood Cancer
|
2013
|
1.01
|
|
41
|
Brainstem lesions in neurofibromatosis type 1.
|
Neurosurgery
|
2007
|
1.01
|
|
42
|
Everyday cognitive function after craniopharyngioma in childhood.
|
Pediatr Neurol
|
2006
|
1.01
|
|
43
|
Antiangiogenic metronomic therapy for children with recurrent embryonal brain tumors.
|
Pediatr Blood Cancer
|
2011
|
1.00
|
|
44
|
Outcome of pediatric pineoblastoma after surgery, radiation and chemotherapy.
|
J Neurooncol
|
2008
|
1.00
|
|
45
|
Development of a parent-report cognitive function item bank using item response theory and exploration of its clinical utility in computerized adaptive testing.
|
J Pediatr Psychol
|
2011
|
1.00
|
|
46
|
Psychosocial and behavioral functioning among pediatric brain tumor survivors.
|
J Neurooncol
|
2003
|
0.98
|
|
47
|
Phase II study of cilengitide in the treatment of refractory or relapsed high-grade gliomas in children: a report from the Children's Oncology Group.
|
Neuro Oncol
|
2013
|
0.97
|
|
48
|
Future of clinical genomics in pediatric oncology.
|
J Clin Oncol
|
2013
|
0.95
|
|
49
|
AAL881, a novel small molecule inhibitor of RAF and vascular endothelial growth factor receptor activities, blocks the growth of malignant glioma.
|
Cancer Res
|
2006
|
0.95
|
|
50
|
Angiogenesis inhibitors and hypoxia.
|
Nat Med
|
2003
|
0.94
|
|
51
|
Therapeutic potential of thiazolidinediones as anticancer agents.
|
Expert Opin Investig Drugs
|
2003
|
0.94
|
|
52
|
Medical, psychological, cognitive and educational late-effects in pediatric low-grade glioma survivors treated with surgery only.
|
Pediatr Blood Cancer
|
2009
|
0.94
|
|
53
|
Challenges with defining response to antitumor agents in pediatric neuro-oncology: a report from the response assessment in pediatric neuro-oncology (RAPNO) working group.
|
Pediatr Blood Cancer
|
2013
|
0.93
|
|
54
|
Molecular aspects, clinical aspects and possible treatment modalities for Costello syndrome: Proceedings from the 1st International Costello Syndrome Research Symposium 2007.
|
Am J Med Genet A
|
2008
|
0.93
|
|
55
|
Parent-perceived child cognitive function: results from a sample drawn from the US general population.
|
Childs Nerv Syst
|
2010
|
0.92
|
|
56
|
DTI assessment of the brainstem white matter tracts in pediatric BSG before and after therapy: a report from the Pediatric Brain Tumor Consortium.
|
Childs Nerv Syst
|
2010
|
0.92
|
|
57
|
Moving forward with metronomic chemotherapy: meeting report of the 2nd International Workshop on Metronomic and Anti-Angiogenic Chemotherapy in Paediatric Oncology.
|
Transl Oncol
|
2011
|
0.92
|
|
58
|
Phase II study of thalidomide and radiation in children with newly diagnosed brain stem gliomas and glioblastoma multiforme.
|
J Neurooncol
|
2006
|
0.92
|
|
59
|
Pulmonary vein stenosis: expression of receptor tyrosine kinases by lesional cells.
|
Cardiovasc Pathol
|
2006
|
0.92
|
|
60
|
Phase II trial of pirfenidone in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas.
|
Pediatr Blood Cancer
|
2014
|
0.90
|
|
61
|
Sleep dysfunction in long term survivors of craniopharyngioma.
|
J Neurooncol
|
2012
|
0.90
|
|
62
|
Long-term outcome of 4,040 children diagnosed with pediatric low-grade gliomas: an analysis of the Surveillance Epidemiology and End Results (SEER) database.
|
Pediatr Blood Cancer
|
2014
|
0.89
|
|
63
|
Remission of infantile generalized myofibromatosis after interferon alpha therapy.
|
J Pediatr Hematol Oncol
|
2008
|
0.88
|
|
64
|
Inhibition of tumor angiogenesis by oral etoposide.
|
Exp Ther Med
|
2010
|
0.88
|
|
65
|
Proteomic profiling of cerebrospinal fluid identifies prostaglandin D2 synthase as a putative biomarker for pediatric medulloblastoma: A pediatric brain tumor consortium study.
|
Proteomics
|
2011
|
0.87
|
|
66
|
A prospective phase II trial of vinblastine and methotrexate in multivessel intraluminal pulmonary vein stenosis in infants and children.
|
Congenit Heart Dis
|
2011
|
0.86
|
|
67
|
Small molecule inhibitors in children with malignant gliomas.
|
Pediatr Blood Cancer
|
2009
|
0.86
|
|
68
|
Role of collagen matrix in tumor angiogenesis and glioblastoma multiforme progression.
|
Am J Pathol
|
2013
|
0.85
|
|
69
|
Neuropsychological functioning after surgery in children treated for brain tumor.
|
Neurosurgery
|
2003
|
0.85
|
|
70
|
A small-molecule IAP inhibitor overcomes resistance to cytotoxic therapies in malignant gliomas in vitro and in vivo.
|
Neuro Oncol
|
2011
|
0.85
|
|
71
|
Lonafarnib (SCH66336) improves the activity of temozolomide and radiation for orthotopic malignant gliomas.
|
J Neurooncol
|
2011
|
0.85
|
|
72
|
Chemotherapy for progressive low-grade gliomas in children older than ten years: the Dana-Farber experience.
|
Pediatr Hematol Oncol
|
2003
|
0.84
|
|
73
|
New strategies in pediatric gliomas: molecular advances in pediatric low-grade gliomas as a model.
|
Clin Cancer Res
|
2013
|
0.84
|
|
74
|
Long-term clinical outcomes following treatment of childhood craniopharyngioma.
|
Pediatr Blood Cancer
|
2010
|
0.83
|
|
75
|
Cutaneovisceral angiomatosis with thrombocytopenia.
|
Pediatr Dev Pathol
|
2005
|
0.82
|
|
76
|
PPARs: A Double-Edged Sword in Cancer Therapy?
|
PPAR Res
|
2009
|
0.82
|
|
77
|
Marked regression of metastatic pilocytic astrocytoma during treatment with imatinib mesylate (STI-571, Gleevec): a case report and laboratory investigation.
|
J Pediatr Hematol Oncol
|
2003
|
0.82
|
|
78
|
The growing role of eicosanoids in tissue regeneration, repair, and wound healing.
|
Prostaglandins Other Lipid Mediat
|
2013
|
0.82
|
|
79
|
Recurrence after gross-total resection of low-grade pediatric brain tumors: the frequency and timing of postoperative imaging.
|
J Neurosurg Pediatr
|
2014
|
0.81
|
|
80
|
Pediatric neuro-oncology: current status and future directions.
|
Asia Pac J Clin Oncol
|
2012
|
0.81
|
|
81
|
Specific uptake of 99mTc-NC100692, an αvβ3-targeted imaging probe, in subcutaneous and orthotopic tumors.
|
Nucl Med Biol
|
2013
|
0.81
|
|
82
|
Differences in molecular genetics between pediatric and adult malignant astrocytomas: age matters.
|
Future Oncol
|
2012
|
0.79
|
|
83
|
Initial cutaneous manifestations of Hutchinson-Gilford progeria syndrome.
|
Pediatr Dermatol
|
2014
|
0.79
|
|
84
|
Quantification of water diffusion and relaxation times of human U87 tumors in a mouse model.
|
NMR Biomed
|
2004
|
0.79
|
|
85
|
A prospective study of radiographic manifestations in Hutchinson-Gilford progeria syndrome.
|
Pediatr Radiol
|
2012
|
0.79
|
|
86
|
Prognostic value of tumor microinvasion and metalloproteinases expression in intracranial pediatric ependymomas.
|
J Neuropathol Exp Neurol
|
2008
|
0.78
|
|
87
|
Metachronous mediastinal seminoma occurring after intracranial germinoma in an adolescent.
|
J Pediatr Hematol Oncol
|
2009
|
0.78
|
|
88
|
Multidisciplinary pediatric brain tumor clinics: the key to successful treatment?
|
CNS Oncol
|
2015
|
0.78
|
|
89
|
Antiangiogenic (metronomic) chemotherapy for brain tumors: current and future perspectives.
|
Expert Opin Investig Drugs
|
2009
|
0.78
|
|
90
|
Myxopapillary ependymomas in children: imaging, treatment and outcomes.
|
J Neurooncol
|
2016
|
0.77
|
|
91
|
Association of rapidly progressive moyamoya syndrome with bevacizumab treatment for glioblastoma in a child with neurofibromatosis type 1.
|
J Child Neurol
|
2010
|
0.77
|
|
92
|
Pediatric brainstem gliomas: new understanding leads to potential new treatments for two very different tumors.
|
Curr Oncol Rep
|
2015
|
0.77
|
|
93
|
A phase-1 pharmacokinetic optimal dosing study of intraventricular topotecan for children with neoplastic meningitis: a Pediatric Brain Tumor Consortium study.
|
Pediatr Blood Cancer
|
2012
|
0.76
|
|
94
|
Predictors of neoplastic disease in children with isolated pituitary stalk thickening.
|
Pediatr Blood Cancer
|
2013
|
0.76
|
|
95
|
Bone density in post-pubertal adolescent survivors of childhood brain tumors.
|
Pediatr Blood Cancer
|
2011
|
0.76
|
|
96
|
Psychological adjustment of 'surgery-only' pediatric neuro-oncology patients: a retrospective analysis.
|
Psychooncology
|
2002
|
0.76
|
|
97
|
Epigenetics in clinical management of children and adolescents with brain tumors.
|
Curr Cancer Drug Targets
|
2017
|
0.75
|
|
98
|
Concomitant Use of Panobinostat and Reirradiation in Progressive DIPG: Report of 2 Cases.
|
J Pediatr Hematol Oncol
|
2017
|
0.75
|
|
99
|
Paucicellular Fibrointimal Proliferation Characterizes Pediatric Pulmonary Vein Stenosis: Clinicopathologic Analysis of 213 Samples From 97 Patients.
|
Am J Surg Pathol
|
2017
|
0.75
|
|
100
|
Recurrent ascites in a patient with low-grade astrocytoma and ventriculo-peritoneal shunt treated with the multikinase inhibitor sorafenib.
|
J Pediatr Hematol Oncol
|
2014
|
0.75
|
|
101
|
Transverse myelitis after therapy for primitive neuroectodermal tumors.
|
Pediatr Neurol
|
2006
|
0.75
|
|
102
|
A prospective, blinded analysis of A-PROTEIN (recoverin or CAR protein) levels in pediatric patients with central nervous system tumors.
|
Pediatr Blood Cancer
|
2009
|
0.75
|
|
103
|
Central Versus Extraventricular Neurocytoma in Children: A Clinicopathologic Comparison and Review of the Literature.
|
J Pediatr Hematol Oncol
|
2016
|
0.75
|
|
104
|
Treatment of low-grade gliomas in children: an update.
|
Expert Rev Neurother
|
2004
|
0.75
|