| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Primary mouse hepatocytes for systems biology approaches: a standardized in vitro system for modelling of signal transduction pathways.
|
Syst Biol (Stevenage)
|
2006
|
1.63
|
|
2
|
Two-year results from an open-label, multicentre, phase III study evaluating the safety and efficacy of canakinumab in patients with cryopyrin-associated periodic syndrome across different severity phenotypes.
|
Ann Rheum Dis
|
2011
|
1.15
|
|
3
|
Drug levels: therapeutic and toxic serum/plasma concentrations of common drugs.
|
J Clin Monit Comput
|
1999
|
1.08
|
|
4
|
Investigations on the pharmacokinetics of alpha-lipoic acid in healthy volunteers.
|
Int J Clin Pharmacol Ther
|
1998
|
1.07
|
|
5
|
Cyclophosphamide and related anticancer drugs.
|
J Chromatogr B Biomed Sci Appl
|
2001
|
1.06
|
|
6
|
CYP2C and IL-6 expression in breast cancer.
|
Breast
|
2004
|
0.88
|
|
7
|
[The pharmacokinetics of bendamustine (Cytostasane) in humans].
|
Pharmazie
|
1985
|
0.85
|
|
8
|
Gender difference in ifosfamide metabolism by human liver microsomes.
|
Eur J Drug Metab Pharmacokinet
|
2001
|
0.85
|
|
9
|
HPLC-methods for determination of lipoic acid and its reduced form in human plasma.
|
Int J Clin Pharmacol Ther Toxicol
|
1992
|
0.83
|
|
10
|
Time-dependent inhibition of glioblastoma cell proliferation by dexamethasone.
|
J Neurooncol
|
2001
|
0.82
|
|
11
|
[Pharmacokinetics of bendamustin (Cytostasan) in B6D2F1-mice].
|
Pharmazie
|
1991
|
0.81
|
|
12
|
CYP3A4, CYP2C9 and CYP2B6 expression and ifosfamide turnover in breast cancer tissue microsomes.
|
Br J Cancer
|
2004
|
0.80
|
|
13
|
P450-expression in brain tumors.
|
Oncol Res
|
1999
|
0.79
|
|
14
|
D2 dopamine receptor occupancy, risperidone plasma level and extrapyramidal motor symptoms in previously drug-free schizophrenic patients.
|
Int J Clin Pharmacol Ther
|
2005
|
0.78
|
|
15
|
High-performance liquid chromatography methods for determination of lipoic and dihydrolipoic acid in human plasma.
|
Methods Enzymol
|
1997
|
0.78
|
|
16
|
Na,K-ATPase in excitation-contraction coupling of vascular smooth muscle from cattle.
|
Acta Biol Med Ger
|
1979
|
0.78
|
|
17
|
Haloperidol serum concentrations and D2 dopamine receptor occupancy during low-dose treatment with haloperidol decanoate.
|
Int Clin Psychopharmacol
|
1997
|
0.77
|
|
18
|
Cisplatin (CDDP)-induced radiation resistance is not associated with CDDP resistance in 86HG39 and A172 malignant glioma cells.
|
Eur J Cancer
|
1999
|
0.77
|
|
19
|
[Bioavailability of cyclophosphamide following oral administration in high doses].
|
Onkologie
|
1984
|
0.77
|
|
20
|
Determination of nicotine and cotinine in human serum by means of LC/MS.
|
J Chromatogr B Analyt Technol Biomed Life Sci
|
2010
|
0.77
|
|
21
|
Modulation of multidrug resistance in human leukemia cells with mdr1-targeted antisense oligonucleotides using variable treatment schedules.
|
Int J Clin Pharmacol Ther
|
2000
|
0.76
|
|
22
|
[Synthesis of a potential metabolite of the carcinostatic bendamustin (Cytostasen)].
|
Pharmazie
|
1991
|
0.76
|
|
23
|
Evaluation of the pharmacokinetics of dalteparin in patients with renal insufficiency.
|
Int J Clin Pharmacol Ther
|
2006
|
0.76
|
|
24
|
Poisoning with tilidine and naloxone: toxicokinetic and clinical observations.
|
Hum Exp Toxicol
|
1998
|
0.75
|
|
25
|
An ouabain-insensitive Na-ATPase of the arterial vascular muscle cell and its relation to ouabain-sensitive Na,K-ATPase.
|
Acta Biol Med Ger
|
1979
|
0.75
|
|
26
|
In vitro tolerance to inhibition by ethanol of N-methyl-D-aspartate-induced depolarization in locus coeruleus neurons of behaviorally ethanol-tolerant rats.
|
Neurochem Int
|
2001
|
0.75
|
|
27
|
Survival after massive "ecstasy" (MDMA) ingestion.
|
Intensive Care Med
|
1999
|
0.75
|
|
28
|
[The effect of oral trapidil therapy on clinical and hemorheological parameters in arteriosclerosis obliterans in comparison to pentoxifylline--a pilot study].
|
Z Gesamte Inn Med
|
1991
|
0.75
|
|
29
|
[Methodology of the colorimetric determination of alkylating cytostatics with 4-(4'-nitrobenzyl)pyridine (NBP) in plasma].
|
Pharmazie
|
1982
|
0.75
|
|
30
|
Determination of lipoic acid in human plasma by high-performance liquid chromatography with electrochemical detection.
|
J Chromatogr B Biomed Appl
|
1995
|
0.75
|
|
31
|
[Properties and toxicology of polytetrafluoroethylene and its use in industry and medicine].
|
Pharmazie
|
1973
|
0.75
|
|
32
|
[Calcium antagonists--determination of current status and therapeutic significance].
|
Z Gesamte Inn Med
|
1992
|
0.75
|
|
33
|
Influence of leukemia P388 on plasma concentration-time profiles of bendamustine in B6D2F1 mice.
|
Pharmazie
|
1992
|
0.75
|
|
34
|
Plasma pharmacokinetics of adriamycin and antipyrine and its relation to the therapeutic and toxic effects.
|
Int J Clin Pharmacol Ther Toxicol
|
1985
|
0.75
|
|
35
|
Poisoning and severe ventilatory depression after oral ingestion of the industrially produced analgesic mixture tilidine with naloxone (Valoron N solution)
|
Intensive Care Med
|
1998
|
0.75
|
|
36
|
Determination of terephthalic acid isopropylamide in urine with a liquid chromatography/mass spectrometry (LC/MS) method.
|
J Clin Lab Anal
|
2008
|
0.75
|
|
37
|
[Absorption of high doses of cyclophosphamide given orally].
|
Pharmazie
|
1983
|
0.75
|
|
38
|
Pharmacokinetics of oral talinolol following a single dose and during steady state in patients with chronic renal failure and healthy volunteers.
|
Int J Clin Pharmacol Ther
|
2001
|
0.75
|
|
39
|
Characterization of Mg-ATPase and (Na+ + K+)-stimulated Mg-ATPase in smooth muscular cells of the sheep's common carotid artery.
|
Acta Biol Med Ger
|
1976
|
0.75
|
|
40
|
Modulation of P-glycoprotein-mediated multidrug resistance in a doxorubicin-resistant subline of the human lymphoblastoid cell line CCRF-CEM by phosphorothioate antisense oligonucleotides.
|
Int J Clin Pharmacol Ther
|
1998
|
0.75
|
|
41
|
[Drug interactions with oral anticoagulants and cardiac glycosides].
|
Z Arztl Fortbild (Jena)
|
1981
|
0.75
|
|
42
|
Effect of external sodium and calcium on calcium efflux in arteria carotis of cattle.
|
Acta Biol Med Ger
|
1979
|
0.75
|
|
43
|
IL-1 receptor type I expression in breast cancer.
|
Breast
|
2001
|
0.75
|
|
44
|
[Present state and improvement possibilities of self instruction in the education of medical students].
|
Z Arztl Fortbild (Jena)
|
1977
|
0.75
|
|
45
|
[Experiences with intra-arterial tumor chemotherapy of malignant liver tumors via totally implantable catheter systems].
|
Zentralbl Chir
|
1989
|
0.75
|
|
46
|
[Determination of prazosin (Adversuten) using HPLC and fluorescence detection].
|
Pharmazie
|
1983
|
0.75
|
|
47
|
Sodium flux and lipid spectrum in the erythrocyte membrane in essential hypertension.
|
Int J Clin Pharmacol Ther Toxicol
|
1982
|
0.75
|
|
48
|
[Beta receptor blockers. Their role and therapeutic importance].
|
Z Gesamte Inn Med
|
1991
|
0.75
|
|
49
|
[Recreational athletes and doping--a survey in 11 gyms in the area of Frankfurt/Main].
|
MMW Fortschr Med
|
2013
|
0.75
|
|
50
|
Demonstration of a Mg-ATPase and a Na,K-ATPase from the arteria carotis communis of the sheep.
|
Acta Biol Med Ger
|
1975
|
0.75
|
|
51
|
Pharmacokinetics and clinical toxicity of prilocaine and ropivacaine following combined drug administration in brachial plexus anesthesia.
|
Int J Clin Pharmacol Ther
|
2009
|
0.75
|
|
52
|
[responses of blood pressure, respiration, and renal excretion of sodium, potassium and chloride following stimulation of arterial chemoreceptors with cyanide solutions in various concentrations].
|
Acta Biol Med Ger
|
1971
|
0.75
|
|
53
|
Determination of cyclophosphamide and its metabolites in human plasma by high-performance liquid chromatography-mass spectrometry.
|
J Chromatogr B Biomed Sci Appl
|
1999
|
0.75
|