SM16, an orally active TGF-beta type I receptor inhibitor prevents myofibroblast induction and vascular fibrosis in the rat carotid injury model.

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Published in Arterioscler Thromb Vasc Biol on January 17, 2008

Authors

Kai Fu1, Michael J Corbley, Lihong Sun, Jessica E Friedman, Feng Shan, James L Papadatos, Donald Costa, Frank Lutterodt, Harry Sweigard, Scott Bowes, Michael Choi, P Ann Boriack-Sjodin, Robert M Arduini, Dongyu Sun, Miki N Newman, Xiamei Zhang, Jonathan N Mead, Claudio E Chuaqui, H-Kam Cheung, Xin Zhang, Mark Cornebise, Mary Beth Carter, Serene Josiah, Juswinder Singh, Wen-Cherng Lee, Alan Gill, Leona E Ling

Author Affiliations

1: Department of Pharmacology, Biogen Idec, 14 Cambridge Center, Cambridge, MA 02142, USA.

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