Published in Genetics on January 01, 2008
Microphthalmia-associated transcription factor in melanoma development and MAP-kinase pathway targeted therapy. Pigment Cell Melanoma Res (2015) 1.12
The role of MITF phosphorylation sites during coat color and eye development in mice analyzed by bacterial artificial chromosome transgene rescue. Genetics (2009) 0.99
PW1 gene/paternally expressed gene 3 (PW1/Peg3) identifies multiple adult stem and progenitor cell populations. Proc Natl Acad Sci U S A (2011) 0.96
C-KIT signaling depends on microphthalmia-associated transcription factor for effects on cell proliferation. PLoS One (2011) 0.88
Mitf-Mdel, a novel melanocyte/melanoma-specific isoform of microphthalmia-associated transcription factor-M, as a candidate biomarker for melanoma. BMC Med (2010) 0.85
In vivo role of alternative splicing and serine phosphorylation of the microphthalmia-associated transcription factor. Genetics (2012) 0.83
Allele-specific genetic interactions between Mitf and Kit affect melanocyte development. Pigment Cell Melanoma Res (2010) 0.82
The evolutionary fate and consequences of duplicate genes. Science (2000) 24.22
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma. Nature (2005) 15.28
Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene. Cell (1991) 14.23
Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein. Cell (1993) 5.00
Epiblast-restricted Cre expression in MORE mice: a tool to distinguish embryonic vs. extra-embryonic gene function. Genesis (2000) 4.97
Duplication and divergence: the evolution of new genes and old ideas. Annu Rev Genet (2004) 4.63
Melanocytes and the microphthalmia transcription factor network. Annu Rev Genet (2004) 3.78
The color loci of mice--a genetic century. Pigment Cell Res (2003) 3.47
microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family. Genes Dev (1994) 3.44
c-Kit triggers dual phosphorylations, which couple activation and degradation of the essential melanocyte factor Mi. Genes Dev (2000) 3.13
The evolution of mammalian gene families. PLoS One (2006) 3.04
The evolutionary demography of duplicate genes. J Struct Funct Genomics (2003) 2.87
Gene duplication: a drive for phenotypic diversity and cause of human disease. Annu Rev Genomics Hum Genet (2007) 2.16
Melanocyte development in vivo and in neural crest cell cultures: crucial dependence on the Mitf basic-helix-loop-helix-zipper transcription factor. Development (1997) 1.69
A helix-loop-helix transcription factor-like gene is located at the mi locus. J Biol Chem (1993) 1.66
High-frequency genetic reversion mediated by a DNA duplication: the mouse pink-eyed unstable mutation. Proc Natl Acad Sci U S A (1993) 1.61
The other pigment cell: specification and development of the pigmented epithelium of the vertebrate eye. Pigment Cell Res (2006) 1.59
Mutations in microphthalmia, the mouse homolog of the human deafness gene MITF, affect neuroepithelial and neural crest-derived melanocytes differently. Mech Dev (1998) 1.49
Direct molecular identification of the mouse pink-eyed unstable mutation by genome scanning. Science (1991) 1.49
Somatic and germ-line reverse mutation rates of the retrovirus-induced dilute coat-color mutation of DBA mice. Proc Natl Acad Sci U S A (1988) 1.39
Genomic, transcriptional and mutational analysis of the mouse microphthalmia locus. Genetics (2000) 1.37
Genomic analysis of the Microphthalmia locus and identification of the MITF-J/Mitf-J isoform. Gene (2005) 1.35
An L1 element intronic insertion in the black-eyed white (Mitf[mi-bw]) gene: the loss of a single Mitf isoform responsible for the pigmentary defect and inner ear deafness. Hum Mol Genet (1999) 1.32
Cloning of MITF, the human homolog of the mouse microphthalmia gene and assignment to chromosome 3p14.1-p12.3. Hum Mol Genet (1994) 1.23
Interallelic complementation at the mouse Mitf locus. Genetics (2003) 1.02
Gene localization and syntenic mapping by FISH in the dog. Cytogenet Cell Genet (1996) 0.99
Phenotypic reversions at the W/Kit locus mediated by mitotic recombination in mice. Mol Cell Biol (1995) 0.96
Cochlear disorder associated with melanocyte anomaly in mice with a transgenic insertional mutation. Mol Cell Neurosci (1992) 0.95
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron (2011) 18.73
Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome. Nature (2003) 12.10
Interferon-γ links ultraviolet radiation to melanomagenesis in mice. Nature (2011) 3.56
'Educated' dendritic cells act as messengers from memory to naive T helper cells. Nat Immunol (2004) 1.96
Myelodysplasia in autosomal dominant and sporadic monocytopenia immunodeficiency syndrome: diagnostic features and clinical implications. Haematologica (2011) 1.89
Chx10 repression of Mitf is required for the maintenance of mammalian neuroretinal identity. Development (2004) 1.79
A regulatory loop involving PAX6, MITF, and WNT signaling controls retinal pigment epithelium development. PLoS Genet (2012) 1.72
Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development. Proc Natl Acad Sci U S A (2002) 1.70
The other pigment cell: specification and development of the pigmented epithelium of the vertebrate eye. Pigment Cell Res (2006) 1.59
Genetics of carney triad: recurrent losses at chromosome 1 but lack of germline mutations in genes associated with paragangliomas and gastrointestinal stromal tumors. J Clin Endocrinol Metab (2007) 1.57
Differentiation of human bone marrow-derived cells into buccal epithelial cells in vivo: a molecular analytical study. Lancet (2003) 1.56
Alternative promoter use in eye development: the complex role and regulation of the transcription factor MITF. Development (2008) 1.50
The concerted action of Meox homeobox genes is required upstream of genetic pathways essential for the formation, patterning and differentiation of somites. Development (2003) 1.37
The Chapel Hill hemophilia A dog colony exhibits a factor VIII gene inversion. Proc Natl Acad Sci U S A (2002) 1.34
The new paradigm: retinal pigment epithelium cells generated from embryonic or induced pluripotent stem cells. Pigment Cell Melanoma Res (2010) 1.32
The microphthalmia-associated transcription factor Mitf interacts with beta-catenin to determine target gene expression. Mol Cell Biol (2006) 1.31
Sumoylation modulates transcriptional activity of MITF in a promoter-specific manner. Pigment Cell Res (2005) 1.28
miR-148 regulates Mitf in melanoma cells. PLoS One (2010) 1.21
Regulation of telomere length and suppression of genomic instability in human somatic cells by Ku86. Mol Cell Biol (2004) 1.20
TREM-like transcript-1 protects against inflammation-associated hemorrhage by facilitating platelet aggregation in mice and humans. J Clin Invest (2009) 1.20
EGFRvIII expression and PTEN loss synergistically induce chromosomal instability and glial tumors. Neuro Oncol (2008) 1.18
DNA damage responses by human ELG1 in S phase are important to maintain genomic integrity. Cell Cycle (2009) 1.18
MITF and cell proliferation: the role of alternative splice forms. Pigment Cell Res (2005) 1.10
The G12 family of heterotrimeric G proteins and Rho GTPase mediate Sonic hedgehog signalling. Genes Cells (2004) 1.09
Deregulated Cdk5 activity is involved in inducing Alzheimer's disease. Arch Med Res (2012) 1.08
A genomic map of a 6-Mb region at 13q21-q22 implicated in cancer development: identification and characterization of candidate genes. Hum Genet (2001) 1.04
Evolutionary sequence comparison of the Mitf gene reveals novel conserved domains. Pigment Cell Res (2007) 1.04
Interallelic complementation at the mouse Mitf locus. Genetics (2003) 1.02
Lack of the ventral anterior homeodomain transcription factor VAX1 leads to induction of a second pituitary. Development (2011) 1.00
Interspecies difference in the regulation of melanocyte development by SOX10 and MITF. Proc Natl Acad Sci U S A (2006) 0.99
The role of MITF phosphorylation sites during coat color and eye development in mice analyzed by bacterial artificial chromosome transgene rescue. Genetics (2009) 0.99
The basic helix-loop-helix leucine zipper transcription factor Mitf is conserved in Drosophila and functions in eye development. Genetics (2004) 0.98
Lack of the mesodermal homeodomain protein MEOX1 disrupts sclerotome polarity and leads to a remodeling of the cranio-cervical joints of the axial skeleton. Dev Biol (2009) 0.92
Individual adult human neurons display aneuploidy: detection by fluorescence in situ hybridization and single neuron PCR. Cell Cycle (2005) 0.92
Statistically designing microarrays and microarray experiments to enhance sensitivity and specificity. Brief Bioinform (2006) 0.91
Cell-autonomous and cell non-autonomous signaling through endothelin receptor B during melanocyte development. Development (2004) 0.91
Restricted leucine zipper dimerization and specificity of DNA recognition of the melanocyte master regulator MITF. Genes Dev (2012) 0.91
Advantages of q-PCR as a method of screening for gene targeting in mammalian cells using conventional and whole BAC-based constructs. Nucleic Acids Res (2008) 0.90
Chromosome 8 BAC array comparative genomic hybridization and expression analysis identify amplification and overexpression of TRMT12 in breast cancer. Genes Chromosomes Cancer (2007) 0.89
A female with complete lack of Müllerian fusion, postaxial polydactyly, and tetralogy of fallot: genetic heterogeneity of McKusick-Kaufman syndrome or a unique syndrome? Am J Med Genet A (2004) 0.86
Mitotic recombination of chromosome arm 17q as a cause of loss of heterozygosity of NF1 in neurofibromatosis type 1-associated glomus tumors. Genes Chromosomes Cancer (2012) 0.86
The basic-helix-loop-helix-leucine zipper gene Mitf: analysis of alternative promoter choice and splicing. Methods Mol Biol (2010) 0.85
Juvenile myelomonocytic leukemia due to a germline CBL Y371C mutation: 35-year follow-up of a large family. Hum Genet (2015) 0.84
In vivo role of alternative splicing and serine phosphorylation of the microphthalmia-associated transcription factor. Genetics (2012) 0.83
Transcription factor zinc finger and BTB domain 1 is essential for lymphocyte development. J Immunol (2012) 0.83
Comparative sequence analyses reveal sites of ancestral chromosomal fusions in the Indian muntjac genome. Genome Biol (2008) 0.82
Common genetic changes in hereditary and sporadic pituitary adenomas detected by comparative genomic hybridization. Genes Chromosomes Cancer (2005) 0.82
Genetics of low spinal muscular atrophy carrier frequency in sub-Saharan Africa. Ann Neurol (2014) 0.82
Allele-specific genetic interactions between Mitf and Kit affect melanocyte development. Pigment Cell Melanoma Res (2010) 0.82
MITF mutations associated with pigment deficiency syndromes and melanoma have different effects on protein function. Hum Mol Genet (2013) 0.81
The novel mouse microphthalmia mutations Mitfmi-enu5 and Mitfmi-bcc2 produce dominant negative Mitf proteins. Genomics (2004) 0.80
When pigment cells turn into neurons. J Invest Dermatol (2005) 0.80
Acinar cell apoptosis in Serpini2-deficient mice models pancreatic insufficiency. PLoS Genet (2005) 0.78
Vax1/2 genes counteract Mitf-induced respecification of the retinal pigment epithelium. PLoS One (2013) 0.78
Differential activity of c-KIT splice forms is controlled by extracellular peptide insert length. Cell Signal (2013) 0.77
Electroretinographic assessment of retinal function in microphthalmia mutant mice. Exp Eye Res (2004) 0.77
Melanoma in mankind's best friend. Pigment Cell Melanoma Res (2014) 0.76
Unmet needs in melanoma research. Pigment Cell Melanoma Res (2014) 0.76
Minimal evidence for a direct involvement of twisted gastrulation homolog 1 (TWSG1) gene in human holoprosencephaly. Mol Genet Metab (2010) 0.76
Generation of a cre recombinase-conditional Nos1ap over-expression transgenic mouse. Biotechnol Lett (2014) 0.76
Cellular calibrators to quantitate T-cell receptor excision circles (TRECs) in clinical samples. Mol Genet Metab (2012) 0.76
All for one, one for all: alternative promoters and Mitf. Pigment Cell Melanoma Res (2008) 0.76
On the edge. Pigment Cell Melanoma Res (2012) 0.75
Tandem Duplication of Exons 1-7 Neither Impairs ATP7A Expression Nor Causes a Menkes Disease Phenotype. JIMD Rep (2015) 0.75
Ribosomes and p53 - a new KIT for skin darkening. Pigment Cell Melanoma Res (2007) 0.75
Warp, weft, and the tapestry of nature. Pigment Cell Melanoma Res (2012) 0.75
Graphical displays. Pigment Cell Melanoma Res (2017) 0.75
An eye on microphthalmia. Pigment Cell Melanoma Res (2017) 0.75
The immune system in pigment cell biology: villain or hero? Pigment Cell Melanoma Res (2013) 0.75
Futures. Pigment Cell Melanoma Res (2017) 0.75
What shall we do this year? Pigment Cell Melanoma Res (2014) 0.75
Welcome to the New Year! Pigment Cell Melanoma Res (2016) 0.75
Of mice and men … but so much more too! Pigment Cell Melanoma Res (2013) 0.75
Preprints. Pigment Cell Melanoma Res (2016) 0.75
Inspiration, collaboration, and cooperation in the PCMR community. Pigment Cell Melanoma Res (2013) 0.75
The test of time. Pigment Cell Melanoma Res (2013) 0.75
UV tanning--the problem that does not go away. Pigment Cell Melanoma Res (2011) 0.75
[Stem cells: cell differentiation and novel therapies.]. Laeknabladid (2003) 0.75
Animal experimentation--questioned again! Pigment Cell Melanoma Res (2015) 0.75
Of patches, blotches, speckles and stripes. Pigment Cell Melanoma Res (2010) 0.75
The world of pigment cell research. Pigment Cell Melanoma Res (2014) 0.75
Editorial: onward and upward with PCMR. Pigment Cell Melanoma Res (2013) 0.75