Published in Autophagy on January 17, 2008
Pathophysiology, treatment, and animal and cellular models of human ischemic stroke. Mol Neurodegener (2011) 1.48
Autophagy-physiology and pathophysiology. Histochem Cell Biol (2008) 1.31
Neuronal cell death in neurodegenerative diseases: recurring themes around protein handling. J Cell Mol Med (2008) 1.24
Lysosome dysfunction triggers Atg7-dependent neural apoptosis. J Biol Chem (2010) 1.16
Inhibition of autophagy contributes to ischemic postconditioning-induced neuroprotection against focal cerebral ischemia in rats. PLoS One (2012) 1.09
RNA interference-mediated downregulation of Beclin1 attenuates cerebral ischemic injury in rats. Acta Pharmacol Sin (2009) 1.07
Death and survival of neuronal and astrocytic cells in ischemic brain injury: a role of autophagy. Acta Pharmacol Sin (2011) 0.99
β-Asarone protects PC12 cells against OGD/R-induced injury via attenuating Beclin-1-dependent autophagy. Acta Pharmacol Sin (2012) 0.93
Thrombin-induced autophagy: a potential role in intracerebral hemorrhage. Brain Res (2011) 0.88
The role of the ubiquitin proteasome system in ischemia and ischemic tolerance. Neuroscientist (2009) 0.86
Protection against Experimental Stroke by Ganglioside GM1 Is Associated with the Inhibition of Autophagy. PLoS One (2016) 0.82
Differential reliance on autophagy for protection from HSV encephalitis between newborns and adults. PLoS Pathog (2015) 0.82
Excitotoxic glutamate insults block autophagic flux in hippocampal neurons. Brain Res (2014) 0.81
Stimulation of autophagy promotes functional recovery in diabetic rats with spinal cord injury. Sci Rep (2015) 0.81
Glial vascular degeneration in CADASIL. J Alzheimers Dis (2010) 0.81
Impairment of autophagic flux promotes glucose reperfusion-induced neuro2A cell death after glucose deprivation. PLoS One (2013) 0.78
HDAC9 exacerbates endothelial injury in cerebral ischaemia/reperfusion injury. J Cell Mol Med (2016) 0.78
DRAM1 protects neuroblastoma cells from oxygen-glucose deprivation/reperfusion-induced injury via autophagy. Int J Mol Sci (2014) 0.77
The role of autophagy in Nmnat-mediated protection against hypoxia-induced dendrite degeneration. Mol Cell Neurosci (2012) 0.77
Icariin Attenuates OGD/R-Induced Autophagy via Bcl-2-Dependent Cross Talk between Apoptosis and Autophagy in PC12 Cells. Evid Based Complement Alternat Med (2016) 0.76
Autophagy Mediates Astrocyte Death During Zinc-Potentiated Ischemia--Reperfusion Injury. Biol Trace Elem Res (2015) 0.76
The Temporal Pattern, Flux, and Function of Autophagy in Spinal Cord Injury. Int J Mol Sci (2017) 0.75
Impaired autophagosome clearance contributes to neuronal death in a piglet model of neonatal hypoxic-ischemic encephalopathy. Cell Death Dis (2017) 0.75
Autophagosome maturation mediated by Rab7 contributes to neuroprotection of hypoxic preconditioning against global cerebral ischemia in rats. Cell Death Dis (2017) 0.75
Loss of autophagy in the central nervous system causes neurodegeneration in mice. Nature (2006) 21.40
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice. Cell (2007) 14.63
Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice. Science (2004) 6.07
Identification of Tim4 as a phosphatidylserine receptor. Nature (2007) 6.06
RNA-binding protein Musashi family: roles for CNS stem cells and a subpopulation of ependymal cells revealed by targeted disruption and antisense ablation. Proc Natl Acad Sci U S A (2002) 2.79
Impaired flow-dependent control of vascular tone and remodeling in P2X4-deficient mice. Nat Med (2005) 2.59
Inhibition of autophagy prevents hippocampal pyramidal neuron death after hypoxic-ischemic injury. Am J Pathol (2008) 2.57
Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten disease). Am J Pathol (2005) 2.56
Phosphatidylserine-dependent engulfment by macrophages of nuclei from erythroid precursor cells. Nature (2005) 2.45
Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue. Mol Brain (2012) 2.18
The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK-ERK pathway to late endosomes. EMBO J (2009) 2.17
New neurons clear the path of astrocytic processes for their rapid migration in the adult brain. Neuron (2010) 2.12
Grafted human-induced pluripotent stem-cell-derived neurospheres promote motor functional recovery after spinal cord injury in mice. Proc Natl Acad Sci U S A (2011) 2.09
Different apoptotic mechanisms are activated in male and female brains after neonatal hypoxia-ischaemia. J Neurochem (2006) 1.87
Bafilomycin A1 inhibits chloroquine-induced death of cerebellar granule neurons. Mol Pharmacol (2006) 1.80
The MAP1-LC3 conjugation system is involved in lipid droplet formation. Biochem Biophys Res Commun (2009) 1.77
Nesfatin-1-regulated oxytocinergic signaling in the paraventricular nucleus causes anorexia through a leptin-independent melanocortin pathway. Cell Metab (2009) 1.66
Cathepsin D deficiency induces persistent neurodegeneration in the absence of Bax-dependent apoptosis. J Neurosci (2007) 1.52
Cytoplasmic reactive oxygen species and SOD1 regulate bone mass during mechanical unloading. J Bone Miner Res (2013) 1.51
Participation of autophagy in renal ischemia/reperfusion injury. Biochem Biophys Res Commun (2008) 1.46
Discovery of a second form of tripartite complex containing gH-gL of human herpesvirus 6 and observations on CD46. J Virol (2004) 1.37
GPHR is a novel anion channel critical for acidification and functions of the Golgi apparatus. Nat Cell Biol (2008) 1.33
Autophagy-physiology and pathophysiology. Histochem Cell Biol (2008) 1.31
Human herpesvirus-6 induces MVB formation, and virus egress occurs by an exosomal release pathway. Traffic (2008) 1.31
Free fatty acids stimulate autophagy in pancreatic β-cells via JNK pathway. Biochem Biophys Res Commun (2010) 1.21
Survival of developing motor neurons mediated by Rho GTPase signaling pathway through Rho-kinase. J Neurosci (2004) 1.21
Involvement of two different cell death pathways in retinal atrophy of cathepsin D-deficient mice. Mol Cell Neurosci (2003) 1.21
CLC-3 deficiency leads to phenotypes similar to human neuronal ceroid lipofuscinosis. Genes Cells (2002) 1.20
Human IAPP-induced pancreatic β cell toxicity and its regulation by autophagy. J Clin Invest (2014) 1.19
LC3, a microtubule-associated protein1A/B light chain3, is involved in cytoplasmic lipid droplet formation. Biochem Biophys Res Commun (2010) 1.18
Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes. Proc Natl Acad Sci U S A (2011) 1.16
Motor neuron-specific disruption of proteasomes, but not autophagy, replicates amyotrophic lateral sclerosis. J Biol Chem (2012) 1.15
Participation of autophagy in the degeneration process of rat hepatocytes after transplantation following prolonged cold preservation. Arch Histol Cytol (2005) 1.14
RANKL-induced expression of tetraspanin CD9 in lipid raft membrane microdomain is essential for cell fusion during osteoclastogenesis. J Bone Miner Res (2006) 1.14
Ablation of C/EBPbeta alleviates ER stress and pancreatic beta cell failure through the GRP78 chaperone in mice. J Clin Invest (2009) 1.13
Loss of ALS2/Alsin exacerbates motor dysfunction in a SOD1-expressing mouse ALS model by disturbing endolysosomal trafficking. PLoS One (2010) 1.12
Sleeping beauty transposon-based phenotypic analysis of mice: lack of Arpc3 results in defective trophoblast outgrowth. Mol Cell Biol (2006) 1.09
Degradation of nuclear DNA by DNase II-like acid DNase in cortical fiber cells of mouse eye lens. FEBS J (2007) 1.08
Insights into the phosphoregulation of beta-secretase sorting signal by the VHS domain of GGA1. Traffic (2004) 1.07
Global analysis of shear stress-responsive genes in vascular endothelial cells. J Atheroscler Thromb (2003) 1.07
Effects of RNA interference of Atg4B on the limited proteolysis of LC3 in PC12 cells and expression of Atg4B in various rat tissues. Autophagy (2006) 1.04
Effect on endothelial cell gene expression of shear stress, oxygen concentration, and low-density lipoprotein as studied by a novel flow cell culture system. Free Radic Biol Med (2004) 1.03
c-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis. Sci Signal (2012) 1.01
Rhomboid protease PARL mediates the mitochondrial membrane potential loss-induced cleavage of PGAM5. J Biol Chem (2012) 0.98
Identification of phospholipid scramblase 1 as a novel interacting molecule with beta -secretase (beta -site amyloid precursor protein (APP) cleaving enzyme (BACE)). J Biol Chem (2003) 0.98
Characterization of Cln3p, the gene product responsible for juvenile neuronal ceroid lipofuscinosis, as a lysosomal integral membrane glycoprotein. J Neurochem (2003) 0.95
Human herpesvirus 6 open reading frame U14 protein and cellular p53 interact with each other and are contained in the virion. J Virol (2005) 0.95
Participation of autophagy in the initiation of graft dysfunction after rat liver transplantation. Autophagy (2009) 0.94
Developing postmitotic mammalian neurons in vivo lacking Apaf-1 undergo programmed cell death by a caspase-independent, nonapoptotic pathway involving autophagy. J Neurosci (2008) 0.91
Intrasulcal electrocorticography in macaque monkeys with minimally invasive neurosurgical protocols. Front Syst Neurosci (2011) 0.91
Acquisition of T regulatory function in cathepsin L-inhibited T cells by eye-derived CTLA-2alpha during inflammatory conditions. J Immunol (2009) 0.90
RGS18 acts as a negative regulator of osteoclastogenesis by modulating the acid-sensing OGR1/NFAT signaling pathway. J Bone Miner Res (2007) 0.90
Dissociation and dispersion of claudin-3 from the tight junction could be one of the most sensitive indicators of reflux esophagitis in a rat model of the disease. J Gastroenterol (2011) 0.90
Development of Purkinje cell degeneration in a knockin mouse model reveals lysosomal involvement in the pathogenesis of SCA6. Proc Natl Acad Sci U S A (2012) 0.89
Altered regulation of phosphatidylinositol 3-kinase signaling in cathepsin D-deficient brain. Autophagy (2007) 0.89
Ablation of TSC2 enhances insulin secretion by increasing the number of mitochondria through activation of mTORC1. PLoS One (2011) 0.89
Autophagic neuron death. Methods Enzymol (2009) 0.88
Exendin-4 improves β-cell function in autophagy-deficient β-cells. Endocrinology (2013) 0.88
In vivo model for visualizing flap microcirculation of ischemia-reperfusion. Microsurgery (2002) 0.87
A technique to visualize wound bed microcirculation and the acute effect of negative pressure. Wound Repair Regen (2008) 0.87
Generation of a recombinant Oka varicella vaccine expressing mumps virus hemagglutinin-neuraminidase protein as a polyvalent live vaccine. Vaccine (2007) 0.86
Atg9A protein, an autophagy-related membrane protein, is localized in the neurons of mouse brains. J Histochem Cytochem (2010) 0.85
Closer association of mitochondria with lipid droplets in hepatocytes and activation of Kupffer cells in resveratrol-treated senescence-accelerated mice. Histochem Cell Biol (2011) 0.85
Deregulation of pancreas-specific oxidoreductin ERO1β in the pathogenesis of diabetes mellitus. Mol Cell Biol (2014) 0.84
Ablation of Csk in neural crest lineages causes corneal anomaly by deregulating collagen fibril organization and cell motility. Dev Biol (2008) 0.83
ATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint-like inclusion body formation, and selective degeneration of dopaminergic neurons. FEBS Lett (2013) 0.83
A MEN2A family with two asymptomatic carriers affected by unilateral renal agenesis. Endocr J (2013) 0.83
Dorsal bipedicled island skin flap: a new flap model in mice. Scand J Plast Reconstr Surg Hand Surg (2002) 0.82
PAC1 gene knockout reveals an essential role of chaperone-mediated 20S proteasome biogenesis and latent 20S proteasomes in cellular homeostasis. Mol Cell Biol (2010) 0.82
Early-phase redistribution of the cation-independent mannose 6-phosphate receptor by U18666A treatment in HeLa cells. Cell Tissue Res (2004) 0.82
Comparative study of the shell development of hard- and soft-shelled turtles. J Anat (2014) 0.82
Oxygen consumption of keloids and hypertrophic scars. Ann Plast Surg (2008) 0.81
Very-high-dose alpha-tocopherol supplementation increases blood pressure and causes possible adverse central nervous system effects in stroke-prone spontaneously hypertensive rats. J Neurosci Res (2009) 0.81
Effect of vibration on skin blood flow in an in vivo microcirculatory model. Biosci Trends (2007) 0.80
Biogenesis and proteolytic processing of lysosomal DNase II. PLoS One (2013) 0.79
Skin temperature changes induced by strong static magnetic field exposure. Bioelectromagnetics (2003) 0.79
Inefficient phagosome maturation in infant macrophages. Biochem Biophys Res Commun (2008) 0.79
Macroautophagy is essential for killing of intracellular Burkholderia pseudomallei in human neutrophils. Autophagy (2015) 0.79
Effect of hyperthermic preconditioning on the survival of ischemia-reperfused skin flaps: a new skin-flap model in the mouse. J Reconstr Microsurg (2002) 0.79
Bilateral, asymmetric anomalies of the anterior bellies of digastric muscles. J Oral Sci (2011) 0.79
AlphaV beta3 (alphavbeta3) integrin inhibition reduces leukocyte-endothelium interaction in a pressure-induced reperfusion model. Wound Repair Regen (2007) 0.79
Cathepsin L in bone marrow-derived cells is required for retinal and choroidal neovascularization. Am J Pathol (2010) 0.79
Differences in expression patterns of cathepsin C/dipeptidyl peptidase I in normal, pathological and aged mouse central nervous system. Eur J Neurosci (2012) 0.79
Purification, cDNA cloning, and secretory properties of FLRG protein from PC12 cells and the distribution of FLRG mRNA and protein in rat tissues. Arch Histol Cytol (2003) 0.79
Relationships between tropomyosin and myosin heavy chain isoforms in bovine skeletal muscle. Anim Sci J (2009) 0.79
Cellularity of developing subcutaneous adipose tissue in Landrace and Meishan pigs: adipocyte size differences between two breeds. Anim Sci J (2010) 0.79
Flavan-3-ol fraction from cocoa powder promotes mitochondrial biogenesis in skeletal muscle in mice. Lipids Health Dis (2014) 0.78
Resveratrol affects undifferentiated and differentiated PC12 cells differently, particularly with respect to possible differences in mitochondrial and autophagic functions. Eur J Cell Biol (2012) 0.78