Mutation from guanine to adenine in 25S rRNA at the position equivalent to E. coli A2058 does not confer erythromycin sensitivity in Sacchromyces cerevisae.

PubWeight™: 0.90‹?›

🔗 View Article (PMC 2248265)

Published in RNA on January 24, 2008

Authors

Ananth S Bommakanti1, Lasse Lindahl, Janice M Zengel

Author Affiliations

1: Department of Biological Sciences, University of Maryland, Baltimore County, Baltimore, Maryland 21250, USA.

Articles cited by this

5-Fluoroorotic acid as a selective agent in yeast molecular genetics. Methods Enzymol (1987) 17.67

Erythromycin resistance by ribosome modification. Antimicrob Agents Chemother (1995) 9.40

Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria. Nature (2001) 6.40

Macrolide resistance conferred by base substitutions in 23S rRNA. Antimicrob Agents Chemother (2001) 4.17

Antibiotic resistance mutations in 16S and 23S ribosomal RNA genes of Escherichia coli. Nucleic Acids Res (1984) 3.94

Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance. Cell (2005) 3.46

The bacterial ribosome as a target for antibiotics. Nat Rev Microbiol (2005) 3.27

The structures of four macrolide antibiotics bound to the large ribosomal subunit. Mol Cell (2002) 3.07

Biochemical and genetic studies on two different types of erythromycin resistant mutants of Escherichia coli with altered ribosomal proteins. Mol Gen Genet (1973) 2.59

Yeast ribosomal protein L1 is required for the stability of newly synthesized 5S rRNA and the assembly of 60S ribosomal subunits. Mol Cell Biol (1993) 2.40

The ribosomal proteins of Saccharomyces cerevisiae. Methods Cell Biol (1978) 2.31

The mechanism of action of macrolides, lincosamides and streptogramin B reveals the nascent peptide exit path in the ribosome. J Mol Biol (2003) 2.23

Mutations in eukaryotic 18S ribosomal RNA affect translational fidelity and resistance to aminoglycoside antibiotics. EMBO J (1994) 2.08

The biogenesis of mitochondria. 4. The differentiation of mitochondrial and cytoplasmic protein synthesizing systems in vitro by antibiotics. Biochim Biophys Acta (1968) 2.02

The polypeptide tunnel system in the ribosome and its gating in erythromycin resistance mutants of L4 and L22. Mol Cell (2001) 1.94

A new rRNA processing mutant of Saccharomyces cerevisiae. Nucleic Acids Res (1992) 1.88

Ribosomal protein gene sequence changes in erythromycin-resistant mutants of Escherichia coli. J Bacteriol (1994) 1.85

Structural basis for selectivity and toxicity of ribosomal antibiotics. EMBO Rep (2001) 1.61

Cell-free protein synthesis: the association of viral RNA and E. coli ribosomes. Proc Natl Acad Sci U S A (1963) 1.47

The biogenesis of mitochondria, VI. Biochemical basis of the resistance of Saccharomyces cerevisiae toward antibiotics which specifically inhibit mitochondrial protein synthesis. Proc Natl Acad Sci U S A (1968) 1.43

The ribosomal peptidyl transferase center: structure, function, evolution, inhibition. Crit Rev Biochem Mol Biol (2005) 1.42

Complete deletion of yeast chromosomal rDNA repeats and integration of a new rDNA repeat: use of rDNA deletion strains for functional analysis of rDNA promoter elements in vivo. Nucleic Acids Res (2000) 1.41

23S rRNA base pair 2057-2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A-->G. Proc Natl Acad Sci U S A (2005) 1.24

Novel mutations in ribosomal proteins L4 and L22 that confer erythromycin resistance in Escherichia coli. Mol Microbiol (2007) 1.24

A reversible change in the ability of Escherichia coli ribosomes to bind to erythromycin. J Mol Biol (1970) 1.13

Sordarin inhibits fungal protein synthesis by blocking translocation differently to fusidic acid. J Biol Chem (1999) 1.04

Antibiotics targeting ribosomes: crystallographic studies. Curr Drug Targets Infect Disord (2002) 0.96

The macrolide-lincosamide-streptogramin B resistance phenotypes characterized by using a specifically deleted, antibiotic-sensitive strain of Streptomyces lividans. Antimicrob Agents Chemother (1996) 0.93

Articles by these authors

Interactions among the protein and RNA subunits of Saccharomyces cerevisiae nuclear RNase P. Proc Natl Acad Sci U S A (2002) 1.33

Novel mutations in ribosomal proteins L4 and L22 that confer erythromycin resistance in Escherichia coli. Mol Microbiol (2007) 1.24

The extended loops of ribosomal proteins L4 and L22 are not required for ribosome assembly or L4-mediated autogenous control. RNA (2003) 1.17

Phylogenetic analysis of the structure of RNase MRP RNA in yeasts. RNA (2002) 1.14

Effects on translation pausing of alterations in protein and RNA components of the ribosome exit tunnel. J Bacteriol (2008) 1.06

RNase MRP is required for entry of 35S precursor rRNA into the canonical processing pathway. RNA (2009) 1.02

Identification of a functional core in the RNA component of RNase MRP of budding yeasts. Nucleic Acids Res (2004) 0.99

RNA-structural mimicry in Escherichia coli ribosomal protein L4-dependent regulation of the S10 operon. J Biol Chem (2003) 0.95

Surprising flexibility of leader RNA determinants for r-protein L4-mediated transcription termination in the Escherichia coil S10 operon. RNA (2002) 0.84

Regulation of ribosomal protein synthesis in Vibrio cholerae. J Bacteriol (2004) 0.83

Comparative anatomy of a regulatory ribosomal protein. Biochimie (2002) 0.83

Repressed synthesis of ribosomal proteins generates protein-specific cell cycle and morphological phenotypes. Mol Biol Cell (2013) 0.79

Assay of transcription termination by ribosomal protein L4. Methods Enzymol (2003) 0.76