Jennifer A Chan

Author PubWeight™ 91.54‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Gene expression in fixed tissues and outcome in hepatocellular carcinoma. N Engl J Med 2008 9.20
2 The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer. Nat Genet 2009 6.99
3 CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity. Nature 2008 6.24
4 Physical activity and survival after colorectal cancer diagnosis. J Clin Oncol 2006 5.22
5 Subgroup-specific structural variation across 1,000 medulloblastoma genomes. Nature 2012 4.13
6 Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma. Cancer Res 2009 3.77
7 A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors. Proc Natl Acad Sci U S A 2003 3.72
8 Insulin, the insulin-like growth factor axis, and mortality in patients with nonmetastatic colorectal cancer. J Clin Oncol 2008 2.63
9 Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway. Genes Dev 2008 2.61
10 Evaluation of the 8q24 prostate cancer risk locus and MYC expression. Cancer Res 2009 2.54
11 Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers. J Pathol 2011 2.27
12 Efficacy and safety of gemcitabine, oxaliplatin, and bevacizumab in advanced biliary-tract cancers and correlation of changes in 18-fluorodeoxyglucose PET with clinical outcome: a phase 2 study. Lancet Oncol 2009 2.23
13 Oral mTOR inhibitor everolimus in patients with gemcitabine-refractory metastatic pancreatic cancer. J Clin Oncol 2008 2.04
14 An in vivo patient-derived model of endogenous IDH1-mutant glioma. Neuro Oncol 2011 1.70
15 Consensus guidelines for the management and treatment of neuroendocrine tumors. Pancreas 2013 1.65
16 Clinical presentation, recurrence, and survival in patients with neuroendocrine tumors: results from a prospective institutional database. Endocr Relat Cancer 2013 1.62
17 Regulable neural progenitor-specific Tsc1 loss yields giant cells with organellar dysfunction in a model of tuberous sclerosis complex. Proc Natl Acad Sci U S A 2011 1.58
18 Cytogenetic prognostication within medulloblastoma subgroups. J Clin Oncol 2014 1.56
19 Antibodies from inflamed central nervous system tissue recognize myelin oligodendrocyte glycoprotein. J Immunol 2005 1.43
20 CXCR4 inhibition synergizes with cytotoxic chemotherapy in gliomas. Clin Cancer Res 2006 1.42
21 Analysis of the 10q11 cancer risk locus implicates MSMB and NCOA4 in human prostate tumorigenesis. PLoS Genet 2010 1.40
22 TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma. Acta Neuropathol 2013 1.35
23 Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1. Proc Natl Acad Sci U S A 2013 1.33
24 A mouse model of cardiac rhabdomyoma generated by loss of Tsc1 in ventricular myocytes. Hum Mol Genet 2004 1.33
25 Analysis of TSC cortical tubers by deep sequencing of TSC1, TSC2 and KRAS demonstrates that small second-hit mutations in these genes are rare events. Brain Pathol 2010 1.32
26 CNS-PNETs with C19MC amplification and/or LIN28 expression comprise a distinct histogenetic diagnostic and therapeutic entity. Acta Neuropathol 2014 1.28
27 Prediagnostic plasma folate and the risk of death in patients with colorectal cancer. J Clin Oncol 2008 1.14
28 Detection of KIAA1549-BRAF fusion transcripts in formalin-fixed paraffin-embedded pediatric low-grade gliomas. J Mol Diagn 2011 1.11
29 A prospective phase II study of 2-methoxyestradiol administered in combination with bevacizumab in patients with metastatic carcinoid tumors. Cancer Chemother Pharmacol 2010 1.11
30 Relationship between statin use and colon cancer recurrence and survival: results from CALGB 89803. J Natl Cancer Inst 2011 1.06
31 Phase I study of cetuximab, irinotecan, and vandetanib (ZD6474) as therapy for patients with previously treated metastastic colorectal cancer. PLoS One 2012 1.05
32 Migration from a mitogenic niche promotes cell-cycle exit. J Neurosci 2005 1.04
33 Lactate dehydrogenase A silencing in IDH mutant gliomas. Neuro Oncol 2013 1.04
34 Family history and survival after colorectal cancer diagnosis. Cancer 2008 1.04
35 Prognostic significance of MTOR pathway component expression in neuroendocrine tumors. J Clin Oncol 2013 1.02
36 RAS/ERK signaling controls proneural genetic programs in cortical development and gliomagenesis. J Neurosci 2014 0.98
37 A novel C19MC amplified cell line links Lin28/let-7 to mTOR signaling in embryonal tumor with multilayered rosettes. Neuro Oncol 2013 0.96
38 Genetic screen identifies insulin-like growth factor binding protein 5 as a modulator of tamoxifen resistance in breast cancer. Cancer Res 2010 0.92
39 PTGER2 overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype. Cancer Epidemiol Biomarkers Prev 2010 0.92
40 DNA hypermethylation and 1p Loss silence NHE-1 in oligodendroglioma. Ann Neurol 2012 0.91
41 Multivitamin use is not associated with cancer recurrence or survival in patients with stage III colon cancer: findings from CALGB 89803. J Clin Oncol 2010 0.89
42 Heparan sulfate proteoglycans containing a glypican 5 core and 2-O-sulfo-iduronic acid function as Sonic Hedgehog co-receptors to promote proliferation. J Biol Chem 2013 0.88
43 Multi-drug inhibition of the HER pathway in metastatic colorectal cancer: results of a phase I study of pertuzumab plus cetuximab in cetuximab-refractory patients. Invest New Drugs 2013 0.88
44 GSK3 temporally regulates neurogenin 2 proneural activity in the neocortex. J Neurosci 2012 0.86
45 Multicenter phase II study of tivozanib (AV-951) and everolimus (RAD001) for patients with refractory, metastatic colorectal cancer. Oncologist 2013 0.83
46 Neurog1 and Neurog2 control two waves of neuronal differentiation in the piriform cortex. J Neurosci 2014 0.82
47 Post-chemotherapy maturation in supratentorial primitive neuroectodermal tumors. Brain Pathol 2013 0.82
48 IDH mutation detection in formalin-fixed paraffin-embedded gliomas using multiplex PCR and single-base extension. Brain Pathol 2012 0.76
49 Sustained response to weekly vinblastine in 2 children with pilomyxoid astrocytoma associated with diencephalic syndrome. J Pediatr Hematol Oncol 2013 0.75
50 Association Between Somatostatin Receptor Expression and Clinical Outcomes in Neuroendocrine Tumors. Pancreas 2016 0.75
51 Reply to A. Koumarianou et al and J. Hadoux et al. J Clin Oncol 2013 0.75
52 Cell Cycle Protein Expression in Neuroendocrine Tumors: Association of CDK4/CDK6, CCND1, and Phosphorylated Retinoblastoma Protein With Proliferative Index. Pancreas 2017 0.75
53 Anaplastic variant of medulloblastoma mimicking a vestibular schwannoma. J Neurooncol 2006 0.75
54 The North American Neuroendocrine Tumor Society Consensus Guidelines for Surveillance and Medical Management of Midgut Neuroendocrine Tumors. Pancreas 2017 0.75
55 EBV-associated lymphoma and chronic inflammatory demyelinating polyneuropathy in an adult without overt immunodeficiency. Am J Hematol 2002 0.75