Published in Curr Top Microbiol Immunol on January 01, 2008
Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS. Genes Dev (2009) 2.96
CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination. Cell Stem Cell (2010) 2.40
Cross-talk between neural stem cells and immune cells: the key to better brain repair? Nat Neurosci (2012) 1.55
Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling. Brain (2009) 1.49
Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination. Ann Neurol (2010) 1.47
The relevance of animal models in multiple sclerosis research. Pathophysiology (2011) 1.40
Animal models of multiple sclerosis: the good, the bad and the bottom line. Nat Neurosci (2012) 1.25
A genetic mouse model of adult-onset, pervasive central nervous system demyelination with robust remyelination. Brain (2010) 1.24
Insulin resistance and neurodegeneration: roles of obesity, type 2 diabetes mellitus and non-alcoholic steatohepatitis. Curr Opin Investig Drugs (2009) 1.21
Reduced inflammation accompanies diminished myelin damage and repair in the NG2 null mouse spinal cord. J Neuroinflammation (2011) 1.09
Local anesthetic Schwann cell toxicity is time and concentration dependent. Reg Anesth Pain Med (2011) 1.05
Towards improved animal models of neonatal white matter injury associated with cerebral palsy. Dis Model Mech (2010) 1.05
Animal Models of MS Reveal Multiple Roles of Microglia in Disease Pathogenesis. Neurol Res Int (2011) 1.00
Signaling through ERK1/2 controls myelin thickness during myelin repair in the adult central nervous system. J Neurosci (2013) 1.00
Central nervous system remyelination in culture--a tool for multiple sclerosis research. Exp Neurol (2011) 1.00
The liver-brain axis of alcohol-mediated neurodegeneration: role of toxic lipids. Int J Environ Res Public Health (2009) 1.00
Evaluation of a transgenic mouse model of multiple sclerosis with noninvasive methods. Invest Ophthalmol Vis Sci (2011) 0.95
The neural androgen receptor: a therapeutic target for myelin repair in chronic demyelination. Brain (2013) 0.93
Restoring the balance between disease and repair in multiple sclerosis: insights from mouse models. Dis Model Mech (2010) 0.92
Apoptosis of oligodendrocytes in the central nervous system results in rapid focal demyelination. Ann Neurol (2012) 0.91
Central canal ependymal cells proliferate extensively in response to traumatic spinal cord injury but not demyelinating lesions. PLoS One (2014) 0.90
Gene network revealed involvements of Birc2, Birc3 and Tnfrsf1a in anti-apoptosis of injured peripheral nerves. PLoS One (2012) 0.89
Functional consequences of ethidium bromide demyelination of the mouse ventral spinal cord. Exp Neurol (2013) 0.87
Common mechanisms of compensatory respiratory plasticity in spinal neurological disorders. Respir Physiol Neurobiol (2013) 0.86
Combination of electroacupuncture and grafted mesenchymal stem cells overexpressing TrkC improves remyelination and function in demyelinated spinal cord of rats. Sci Rep (2015) 0.86
Swimming exercise ameliorates multiple sclerosis-induced impairment of short-term memory by suppressing apoptosis in the hippocampus of rats. J Exerc Rehabil (2014) 0.84
Stimulation of adult oligodendrogenesis by myelin-specific T cells. Am J Pathol (2011) 0.83
The quest for myelin in the adult brain. Nat Cell Biol (2013) 0.83
Microglial Hv1 proton channel promotes cuprizone-induced demyelination through oxidative damage. J Neurochem (2015) 0.82
Translational control of myelin basic protein expression by ERK2 MAP kinase regulates timely remyelination in the adult brain. J Neurosci (2015) 0.82
Neuroprotective effect of oligodendrocyte precursor cell transplantation in a long-term model of periventricular leukomalacia. Am J Pathol (2009) 0.81
Prox1 Inhibits Proliferation and Is Required for Differentiation of the Oligodendrocyte Cell Lineage in the Mouse. PLoS One (2015) 0.81
Reversible behavioral deficits in rats during a cycle of demyelination-remyelination of the fimbria. PLoS One (2013) 0.81
Astrocyte Activation via Stat3 Signaling Determines the Balance of Oligodendrocyte versus Schwann Cell Remyelination. Am J Pathol (2015) 0.80
Precision Medicine in Multiple Sclerosis: Future of PET Imaging of Inflammation and Reactive Astrocytes. Front Mol Neurosci (2016) 0.80
Accelerated axonal loss following acute CNS demyelination in mice lacking protein tyrosine phosphatase receptor type Z. Am J Pathol (2012) 0.80
Zebrafish regenerate full thickness optic nerve myelin after demyelination, but this fails with increasing age. Acta Neuropathol Commun (2014) 0.78
Cervical spinal demyelination with ethidium bromide impairs respiratory (phrenic) activity and forelimb motor behavior in rats. Neuroscience (2012) 0.77
Intracellular Protein Shuttling: A Mechanism Relevant for Myelin Repair in Multiple Sclerosis? Int J Mol Sci (2015) 0.77
Apolipoprotein E Mimetic Promotes Functional and Histological Recovery in Lysolecithin-Induced Spinal Cord Demyelination in Mice. J Neurol Neurophysiol (2013) 0.77
NG2-proteoglycan-dependent contributions of oligodendrocyte progenitors and myeloid cells to myelin damage and repair. J Neuroinflammation (2015) 0.77
Convergence of cells from the progenitor fraction of adult olfactory bulb tissue to remyelinating glia in demyelinating spinal cord lesions. PLoS One (2009) 0.76
Extracellular cues influencing oligodendrocyte differentiation and (re)myelination. Exp Neurol (2016) 0.76
The EIIIA domain from astrocyte-derived fibronectin mediates proliferation of oligodendrocyte progenitor cells following CNS demyelination. Glia (2014) 0.76
Diffusion-Weighted Magnetic Resonance Imaging Characterization of White Matter Injury Produced by Axon-Sparing Demyelination and Severe Contusion Spinal Cord Injury in Rats. J Neurotrauma (2016) 0.76
Infection as an Environmental Trigger of Multiple Sclerosis Disease Exacerbation. Front Immunol (2015) 0.76
IL4I1 augments CNS remyelination and axonal protection by modulating T cell driven inflammation. Brain (2016) 0.76
Electroacupuncture promotes the proliferation of endogenous neural stem cells and oligodendrocytes in the injured spinal cord of adult rats. Neural Regen Res (2012) 0.75
A mouse model for testing remyelinating therapies. Exp Neurol (2016) 0.75
The HMGB1 signaling pathway activates the inflammatory response in Schwann cells. Neural Regen Res (2015) 0.75
Using temporal genetic switches to synchronize the unfolded protein response in cell populations in vivo. Methods Enzymol (2011) 0.75
Debris clearance by microglia: an essential link between degeneration and regeneration. Brain (2008) 3.36
Schwann cell precursors: a favourable cell for myelin repair in the Central Nervous System. Brain (2007) 1.68
The responses of oligodendrocyte precursor cells, astrocytes and microglia to a cortical stab injury, in the brain. Neuroscience (2004) 1.28
Steroid hormones and neurosteroids in normal and pathological aging of the nervous system. Prog Neurobiol (2003) 1.15
Abnormally phosphorylated tau is associated with neuronal and axonal loss in experimental autoimmune encephalomyelitis and multiple sclerosis. Brain (2008) 1.10
Clinical canine spinal cord injury provides an opportunity to examine the issues in translating laboratory techniques into practical therapy. Spinal Cord (2006) 1.05
Efficient derivation of NPCs, spinal motor neurons and midbrain dopaminergic neurons from hESCs at 3% oxygen. Nat Protoc (2011) 1.01
Increasing local levels of IGF-I mRNA expression using adenoviral vectors does not alter oligodendrocyte remyelination in the CNS of aged rats. Mol Cell Neurosci (2002) 0.98
Derivation of neural precursor cells from human ES cells at 3% O(2) is efficient, enhances survival and presents no barrier to regional specification and functional differentiation. Cell Death Differ (2011) 0.94
Remyelination: the true regeneration of the central nervous system. J Comp Pathol (2013) 0.94
Systemic progesterone administration results in a partial reversal of the age-associated decline in CNS remyelination following toxin-induced demyelination in male rats. Neuropathol Appl Neurobiol (2004) 0.92
Cryopreserved cells isolated from the adult canine olfactory bulb are capable of extensive remyelination following transplantation into the adult rat CNS. Exp Neurol (2002) 0.91
Steroids and the reversal of age-associated changes in myelination and remyelination. Prog Neurobiol (2003) 0.91
Nasal and frontal sinus mucosa of the adult dog contain numerous olfactory sensory neurons and ensheathing glia. Res Vet Sci (2005) 0.82
[Promoting remyelination in multiple sclerosis by endogenous adult neural stem/precursor cells]. Rev Neurol (Paris) (2007) 0.75
Congenital unilateral absence of the corticospinal tract in a Siamese cat. Vet Pathol (2007) 0.75