Antitumor and antimetastatic activity of fucoidan, a sulfated polysaccharide isolated from the Okhotsk Sea Fucus evanescens brown alga.

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Published in Bull Exp Biol Med on June 01, 2007

Authors

T V Alekseyenko1, S Ya Zhanayeva, A A Venediktova, T N Zvyagintseva, T A Kuznetsova, N N Besednova, T A Korolenko

Author Affiliations

1: Institute of Physiology, Siberian Division of Russian Academy of Medical Sciences, Novosibirsk.

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[Chlorophyll-photosensitized reduction of methyl red in detergent solutions]. Biofizika (1979) 0.75

A chemical investigation of the trepang (Stychopus japonicus Selenka): the structure of triterpenoid aglycones obtained from trepang glycosides. Tetrahedron Lett (1969) 0.75

[The effect of translam on the natural resistance indices of the irradiated organism]. Radiats Biol Radioecol (1994) 0.75

[Properties of modified amperometric biosensors based on methanol dehydrogenase and Methylobacterium nodulans cells]. Prikl Biokhim Mikrobiol (2014) 0.75

[Bioactive compounds from marine actinomycetes]. Bioorg Khim (1995) 0.75

[Efficiency of a new synbiotic drink in treatment of chronic diseases of gastrointestinal tract and concomitant dysbacteriosis]. Antibiot Khimioter (2013) 0.75

[Action of bioglycans from marine invertebrates on macrophage functioning]. Antibiotiki (1984) 0.75

[Effect of regulators on bacterial autolysis]. Mikrobiologiia (1982) 0.75

[The effect of the acetylation phenotype on the course severity and outcome of acute viral hepatitis B]. Ter Arkh (1996) 0.75

[Some results and prospects of studies in the area of marine biochemistry and biotechnology]. Bioorg Khim (1993) 0.75