PubRank

Lucio Merlini

Author PubWeight™ 20.82‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Synthesis and cytotoxic activity of a new series of topoisomerase I inhibitors. Bioorg Med Chem Lett 2007 0.93
2 Synthesis and structure-activity relationships of a new series of retinoid-related biphenyl-4-ylacrylic acids endowed with antiproliferative and proapoptotic activity. J Med Chem 2005 0.92
3 A novel atypical retinoid endowed with proapoptotic and antitumor activity. J Med Chem 2003 0.90
4 Natural and semisynthetic azaphilones as a new scaffold for Hsp90 inhibitors. Bioorg Med Chem 2010 0.89
5 Synthesis of (+)-spirolaxine methyl ether. J Org Chem 2006 0.88
6 Antitumor activity of the retinoid-related molecules (E)-3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid (ST1926) and 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid (CD437) in F9 teratocarcinoma: Role of retinoic acid receptor gamma and retinoid-independent pathways. Mol Pharmacol 2006 0.88
7 Synthesis and structure-activity relationships of new antiproliferative and proapoptotic retinoid-related biphenyl-4-yl-acrylic acids. Bioorg Med Chem 2007 0.87
8 Preclinical efficacy of ST1976, a novel camptothecin analog of the 7-oxyiminomethyl series. Biochem Pharmacol 2006 0.86
9 Preclinical profile of antitumor activity of a novel hydrophilic camptothecin, ST1968. Mol Cancer Ther 2008 0.86
10 ST1926, a novel and orally active retinoid-related molecule inducing apoptosis in myeloid leukemia cells: modulation of intracellular calcium homeostasis. Blood 2003 0.85
11 A new group of oxime carbamates as reversible inhibitors of fatty acid amide hydrolase. Bioorg Med Chem Lett 2010 0.85
12 Enol carbamates as inhibitors of fatty acid amide hydrolase (FAAH) endowed with high selectivity for FAAH over the other targets of the endocannabinoid system. ChemMedChem 2010 0.85
13 Design, synthesis, and evaluation of biphenyl-4-yl-acrylohydroxamic acid derivatives as histone deacetylase (HDAC) inhibitors. Eur J Med Chem 2008 0.84
14 Pattern of antitumor activity of a novel camptothecin, ST1481, in a large panel of human tumor xenografts. Clin Cancer Res 2002 0.83
15 Synthesis and cytotoxic activity of polyamine analogues of camptothecin. J Med Chem 2006 0.82
16 Synthesis of photoactivable inhibitors of osteoclast vacuolar ATPase. Bioorg Med Chem 2003 0.81
17 Synthesis, modeling, and RET protein kinase inhibitory activity of 3- and 4-substituted beta-carbolin-1-ones. J Med Chem 2008 0.81
18 Synthesis and cytotoxic activity of substituted luotonin A derivatives. Bioorg Med Chem Lett 2004 0.81
19 Synthesis and cytotoxic activity of new 9-substituted camptothecins. Bioorg Med Chem Lett 2008 0.80
20 Atypical retinoids ST1926 and CD437 are S-phase-specific agents causing DNA double-strand breaks: significance for the cytotoxic and antiproliferative activity. Mol Cancer Ther 2008 0.80
21 Synthesis and cytotoxic activity of substituted 7-aryliminomethyl derivatives of camptothecin. Eur J Med Chem 2004 0.79
22 A new azoxyalkene from a strain of an actinomadura-like fungus. Planta Med 2003 0.79
23 Optimized synthesis and enhanced efficacy of novel triplex-forming camptothecin derivatives based on gimatecan. Bioconjug Chem 2009 0.78
24 General pseudoreceptor model for sweet compounds: a semiquantitative prediction of binding affinity for sweet-tasting molecules. J Med Chem 2002 0.78
25 Synthesis and topoisomerase I inhibitory activity of a novel diazaindeno[2,1-b]phenanthrene analogue of Lamellarin D. Bioorg Med Chem 2011 0.76
26 Isoxazolo(aza)naphthoquinones: a new class of cytotoxic Hsp90 inhibitors. Eur J Med Chem 2012 0.75
27 Identification of a novel arylpiperazine scaffold for fatty acid amide hydrolase inhibition with improved drug disposition properties. Bioorg Med Chem Lett 2012 0.75
28 New retinoid derivatives as back-ups of Adarotene. Bioorg Med Chem 2012 0.75
29 A new 3,4-seco-lupane derivative from Lasianthus gardneri. J Nat Prod 2004 0.75
30 A new synthesis of isoaurones: cytotoxic activity of compounds related to the alleged structure of isoaurostatin. Bioorg Med Chem Lett 2005 0.75
31 Total synthesis of the natural product benzo[j]fluoranthene-4,9-diol: an approach to the synthesis of oxygenated benzo[j]fluoranthenes. J Org Chem 2013 0.75
32 Synthesis and antifungal activity of 2-hydroxy-4,5-methylenedioxyaryl ketones as analogues of kakuol. Chem Biodivers 2010 0.75
33 Synthesis and antifungal activity of a series of N-substituted [2-(2,4-dichlorophenyl)-3-(1,2,4-triazol-1-yl)]propylamines. J Agric Food Chem 2007 0.75