Published in Hypertension on February 07, 2008
Murine prolylcarboxypeptidase depletion induces vascular dysfunction with hypertension and faster arterial thrombosis. Blood (2011) 1.86
Effects of tempol and redox-cycling nitroxides in models of oxidative stress. Pharmacol Ther (2010) 1.66
A redox switch in angiotensinogen modulates angiotensin release. Nature (2010) 1.50
A model of preeclampsia in rats: the reduced uterine perfusion pressure (RUPP) model. Am J Physiol Heart Circ Physiol (2012) 1.24
Vascular oxidative stress: the common link in hypertensive and diabetic vascular disease. J Cardiovasc Pharmacol (2010) 1.13
Spiral arterial remodeling is not essential for normal blood pressure regulation in pregnant mice. Hypertension (2010) 1.06
Adenoviral delivery of VEGF121 early in pregnancy prevents spontaneous development of preeclampsia in BPH/5 mice. Hypertension (2010) 0.99
Vasopressin in preeclampsia: a novel very early human pregnancy biomarker and clinically relevant mouse model. Hypertension (2014) 0.98
Placental ischemia and cardiovascular dysfunction in preeclampsia and beyond: making the connections. Expert Rev Cardiovasc Ther (2008) 0.94
Effect of the anti-oxidant tempol on fetal growth in a mouse model of fetal growth restriction. Biol Reprod (2012) 0.93
The cooperative roles of inflammation and oxidative stress in the pathogenesis of hypertension. Antioxid Redox Signal (2013) 0.92
Timing of ischemic insult alters fetal growth trajectory, maternal angiogenic balance, and markers of renal oxidative stress in the pregnant rat. Am J Physiol Regul Integr Comp Physiol (2012) 0.90
Chronic hypoxia during gestation enhances uterine arterial myogenic tone via heightened oxidative stress. PLoS One (2013) 0.88
Decidual Cox2 inhibition improves fetal and maternal outcomes in a preeclampsia-like mouse model. JCI Insight (2016) 0.85
Preeclampsia, of mice and women. Physiol Genomics (2016) 0.82
Mesenchymal stem cells ameliorate Th1-induced pre-eclampsia-like symptoms in mice via the suppression of TNF-α expression. PLoS One (2014) 0.82
Mouse models for preeclampsia: disruption of redox-regulated signaling. Reprod Biol Endocrinol (2009) 0.81
The Williams-Beuren Syndrome-a window into genetic variants leading to the development of cardiovascular disease. PLoS Genet (2012) 0.81
An increased population of regulatory T cells improves the pathophysiology of placental ischemia in a rat model of preeclampsia. Am J Physiol Regul Integr Comp Physiol (2015) 0.80
From Pre-Clinical Studies to Clinical Trials: Generation of Novel Therapies for Pregnancy Complications. Int J Mol Sci (2015) 0.78
Refinement of telemetry for measuring blood pressure in conscious rats. J Am Assoc Lab Anim Sci (2009) 0.78
Role of peroxiredoxin III in the pathogenesis of pre-eclampsia as evidenced in mice. Oxid Med Cell Longev (2010) 0.77
The effect of tempol administration on the aortic contractile responses in rat preeclampsia model. ISRN Pharmacol (2012) 0.77
Distal-less 3 haploinsufficiency results in elevated placental oxidative stress and altered fetal growth kinetics in the mouse. Placenta (2012) 0.76
Morphometric analysis of the placenta in the New World mouse Necromys lasiurus (Rodentia, Cricetidae): a comparison of placental development in cricetids and murids. Reprod Biol Endocrinol (2013) 0.76
Direct effect of chronic hypoxia in suppressing large conductance Ca(2+) -activated K(+) channel activity in ovine uterine arteries via increasing oxidative stress. J Physiol (2015) 0.76
Fetal programming and environmental exposures: implications for prenatal care and preterm birth. Ann N Y Acad Sci (2012) 0.75
Adverse metabolic phenotype of female offspring exposed to preeclampsia in utero: a characterization of the BPH/5 mouse in postnatal life. Am J Physiol Regul Integr Comp Physiol (2017) 0.75
Long-term Blood Pressure Measurement in Freely Moving Mice Using Telemetry. J Vis Exp (2016) 0.75
Treating the dysfunctional placenta. J Endocrinol (2017) 0.75
Hypertension caused by angiotensin II infusion involves increased superoxide production in the central nervous system. Circ Res (2004) 4.12
Superoxide mediates the actions of angiotensin II in the central nervous system. Circ Res (2002) 3.29
NADPH oxidases of the brain: distribution, regulation, and function. Antioxid Redox Signal (2006) 2.56
Hypertension and cerebrovascular dysfunction. Cell Metab (2008) 2.30
Microdystrophin gene therapy of cardiomyopathy restores dystrophin-glycoprotein complex and improves sarcolemma integrity in the mdx mouse heart. Circulation (2003) 2.22
ACE2 overexpression in the paraventricular nucleus attenuates angiotensin II-induced hypertension. Cardiovasc Res (2011) 2.03
Requirement for Rac1-dependent NADPH oxidase in the cardiovascular and dipsogenic actions of angiotensin II in the brain. Circ Res (2004) 1.98
Recommendations for blood pressure measurement in humans and experimental animals: part 2: blood pressure measurement in experimental animals: a statement for professionals from the Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research. Arterioscler Thromb Vasc Biol (2005) 1.82
Brain-selective overexpression of angiotensin (AT1) receptors causes enhanced cardiovascular sensitivity in transgenic mice. Circ Res (2002) 1.81
Role of CuZn superoxide dismutase on carotid body function in heart failure rabbits. Cardiovasc Res (2008) 1.75
Major role for ACE-independent intrarenal ANG II formation in type II diabetes. Am J Physiol Renal Physiol (2009) 1.75
Targeted viral delivery of Cre recombinase induces conditional gene deletion in cardiovascular circuits of the mouse brain. Physiol Genomics (2004) 1.74
Brain-selective overexpression of human Angiotensin-converting enzyme type 2 attenuates neurogenic hypertension. Circ Res (2009) 1.71
Angiotensin I-converting enzyme type 2 (ACE2) gene therapy improves glycemic control in diabetic mice. Diabetes (2010) 1.57
Nox2-containing NADPH oxidase and Akt activation play a key role in angiotensin II-induced cardiomyocyte hypertrophy. Physiol Genomics (2006) 1.57
Local production of angiotensin II in the subfornical organ causes elevated drinking. J Clin Invest (2007) 1.56
ER stress in the brain subfornical organ mediates angiotensin-dependent hypertension. J Clin Invest (2012) 1.51
ACE2/ANG-(1-7)/Mas pathway in the brain: the axis of good. Am J Physiol Regul Integr Comp Physiol (2010) 1.51
Superoxide mediates angiotensin II-induced influx of extracellular calcium in neural cells. Hypertension (2005) 1.50
Loss of alpha-dystroglycan laminin binding in epithelium-derived cancers is caused by silencing of LARGE. J Biol Chem (2009) 1.46
Redox signaling in central neural regulation of cardiovascular function. Prog Biophys Mol Biol (2004) 1.46
Genetic silencing of Nox2 and Nox4 reveals differential roles of these NADPH oxidase homologues in the vasopressor and dipsogenic effects of brain angiotensin II. Hypertension (2009) 1.45
Angiotensin II type 1 receptor-mediated reduction of angiotensin-converting enzyme 2 activity in the brain impairs baroreflex function in hypertensive mice. Hypertension (2009) 1.45
Differential expression of neuronal ACE2 in transgenic mice with overexpression of the brain renin-angiotensin system. Am J Physiol Regul Integr Comp Physiol (2006) 1.44
Reactive oxygen species in the neuropathogenesis of hypertension. Curr Hypertens Rep (2006) 1.40
MnSOD inhibits proline oxidase-induced apoptosis in colorectal cancer cells. Carcinogenesis (2005) 1.39
Superoxide is involved in the central nervous system activation and sympathoexcitation of myocardial infarction-induced heart failure. Circ Res (2003) 1.37
Role of the NADPH oxidases in the subfornical organ in angiotensin II-induced hypertension. Hypertension (2012) 1.33
Selective gene transfer to key cardiovascular regions of the brain: comparison of two viral vector systems. Hypertension (2002) 1.27
Control of hepatic nuclear superoxide production by glucose 6-phosphate dehydrogenase and NADPH oxidase-4. J Biol Chem (2011) 1.26
Manganese superoxide dismutase suppresses hypoxic induction of hypoxia-inducible factor-1alpha and vascular endothelial growth factor. Oncogene (2005) 1.26
The sweeter side of ACE2: physiological evidence for a role in diabetes. Mol Cell Endocrinol (2008) 1.26
The cerebrovascular dysfunction induced by slow pressor doses of angiotensin II precedes the development of hypertension. Am J Physiol Heart Circ Physiol (2010) 1.24
Genetic ablation of angiotensinogen in the subfornical organ of the brain prevents the central angiotensinergic pressor response. Circ Res (2006) 1.20
A differential role for endocytosis in receptor-mediated activation of Nox1. Antioxid Redox Signal (2010) 1.20
Species-specific inhibitor sensitivity of angiotensin-converting enzyme 2 (ACE2) and its implication for ACE2 activity assays. Am J Physiol Regul Integr Comp Physiol (2011) 1.18
Activator of G protein signaling 3 null mice: I. Unexpected alterations in metabolic and cardiovascular function. Endocrinology (2008) 1.17
ACE2-mediated reduction of oxidative stress in the central nervous system is associated with improvement of autonomic function. PLoS One (2011) 1.16
Pancreatic angiotensin-converting enzyme 2 improves glycemia in angiotensin II-infused mice. Am J Physiol Endocrinol Metab (2013) 1.15
Severe feto-placental abnormalities precede the onset of hypertension and proteinuria in a mouse model of preeclampsia. Biol Reprod (2006) 1.12
Endothelin 1-dependent neurovascular dysfunction in chronic intermittent hypoxia. Hypertension (2012) 1.11
Angiotensin-converting enzyme 2 in the brain: properties and future directions. J Neurochem (2008) 1.11
Deficiency of glutathione peroxidase-1 sensitizes hyperhomocysteinemic mice to endothelial dysfunction. Arterioscler Thromb Vasc Biol (2002) 1.11
Silencing nox4 in the paraventricular nucleus improves myocardial infarction-induced cardiac dysfunction by attenuating sympathoexcitation and periinfarct apoptosis. Circ Res (2010) 1.10
Angiotensin II-dependent hypertension requires cyclooxygenase 1-derived prostaglandin E2 and EP1 receptor signaling in the subfornical organ of the brain. Hypertension (2012) 1.09
Renovascular hypertension in mice with brain-selective overexpression of AT1a receptors is buffered by increased nitric oxide production in the periphery. Circ Res (2004) 1.08
Central cardiovascular circuits contribute to the neurovascular dysfunction in angiotensin II hypertension. J Neurosci (2012) 1.06
Determination of sex differences in activities of angiotensin-converting enzyme 2 (ACE2) requires an activity assay that doesn't underestimate ACE2. Am J Hypertens (2013) 1.05
Targeted inhibition of complement activation prevents features of preeclampsia in mice. Kidney Int (2010) 1.04
Scavenging superoxide selectively in mouse forebrain is associated with improved cardiac function and survival following myocardial infarction. Am J Physiol Regul Integr Comp Physiol (2008) 1.02
Redox regulation of pancreatic cancer cell growth: role of glutathione peroxidase in the suppression of the malignant phenotype. Hum Gene Ther (2004) 1.01
Delayed radioprotection by nuclear transcription factor kappaB -mediated induction of manganese superoxide dismutase in human microvascular endothelial cells after exposure to the free radical scavenger WR1065. Free Radic Biol Med (2005) 1.00
Tempol therapy attenuates medial smooth muscle cell apoptosis and neointima formation after balloon catheter injury in carotid artery of diabetic rats. Am J Physiol Heart Circ Physiol (2005) 1.00
Eradication of metastatic renal cell carcinoma after adenovirus-encoded TNF-related apoptosis-inducing ligand (TRAIL)/CpG immunotherapy. PLoS One (2012) 1.00
Adenoviral delivery of VEGF121 early in pregnancy prevents spontaneous development of preeclampsia in BPH/5 mice. Hypertension (2010) 0.99
Delayed cytoprotection after enhancement of Sod2 (MnSOD) gene expression in SA-NH mouse sarcoma cells exposed to WR-1065, the active metabolite of amifostine. Radiat Res (2002) 0.99
Rab1 GTPase and dimerization in the cell surface expression of angiotensin II type 2 receptor. J Pharmacol Exp Ther (2009) 0.98
Kidney-induced hypertension depends on superoxide signaling in the rostral ventrolateral medulla. Hypertension (2010) 0.98
In vivo bioluminescence imaging reveals redox-regulated activator protein-1 activation in paraventricular nucleus of mice with renovascular hypertension. Hypertension (2010) 0.96
The brain subfornical organ mediates leptin-induced increases in renal sympathetic activity but not its metabolic effects. Hypertension (2013) 0.95
Inhibition of matrix metalloproteinase activity by TIMP-1 gene transfer effectively treats ischemic cardiomyopathy. Circulation (2004) 0.95
Recommendations for blood pressure measurement in animals: summary of an AHA scientific statement from the Council on High Blood Pressure Research, Professional and Public Education Subcommittee. Arterioscler Thromb Vasc Biol (2005) 0.94
Newborn lamb coronary artery reactivity is programmed by early gestation dexamethasone before the onset of systemic hypertension. Am J Physiol Regul Integr Comp Physiol (2005) 0.94
The angiotensin converting enzyme 2/Ang-(1-7) axis in the heart: a role for MAS communication? Circ Res (2008) 0.93
DITPA stimulates arteriolar growth and modifies myocardial postinfarction remodeling. Am J Physiol Heart Circ Physiol (2004) 0.92
Intact renal afferent arteriolar autoregulatory responsiveness in db/db mice. Am J Physiol Renal Physiol (2008) 0.91
Protective effects of PARP-1 knockout on dyslipidemia-induced autonomic and vascular dysfunction in ApoE mice: effects on eNOS and oxidative stress. PLoS One (2009) 0.90
AAV-directed persistent expression of a gene encoding anti-nicotine antibody for smoking cessation. Sci Transl Med (2012) 0.89
Brain-selective overexpression of angiotensin-converting enzyme 2 attenuates sympathetic nerve activity and enhances baroreflex function in chronic heart failure. Hypertension (2011) 0.89
COX-1-derived PGE2 and PGE2 type 1 receptors are vital for angiotensin II-induced formation of reactive oxygen species and Ca(2+) influx in the subfornical organ. Am J Physiol Heart Circ Physiol (2013) 0.89
Longitudinal noninvasive monitoring of transcription factor activation in cardiovascular regulatory nuclei using bioluminescence imaging. Physiol Genomics (2008) 0.88
L-PhGPx expression can be suppressed by antisense oligodeoxynucleotides. Arch Biochem Biophys (2003) 0.88
Genetic redox preconditioning differentially modulates AP-1 and NF kappa B responses following cardiac ischemia/reperfusion injury and protects against necrosis and apoptosis. Mol Ther (2003) 0.88
Angiotensin-converting enzyme 2: central regulator for cardiovascular function. Curr Hypertens Rep (2010) 0.87
Ganglionic action of angiotensin contributes to sympathetic activity in renin-angiotensinogen transgenic mice. Hypertension (2003) 0.87
Enhanced water and salt intake in transgenic mice with brain-restricted overexpression of angiotensin (AT1) receptors. Am J Physiol Regul Integr Comp Physiol (2008) 0.87