Published in Yeast on March 01, 2008
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RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation. Nat Immunol (2004) 5.74
Proteasome subunit Rpn13 is a novel ubiquitin receptor. Nature (2008) 4.76
PICH, a centromere-associated SNF2 family ATPase, is regulated by Plk1 and required for the spindle checkpoint. Cell (2007) 3.80
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NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control. Genes Dev (2009) 3.23
When ubiquitin meets ubiquitin receptors: a signalling connection. Nat Rev Mol Cell Biol (2003) 2.91
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WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity. Nature (2008) 2.86
Inhibition of homologous recombination by the PCNA-interacting protein PARI. Mol Cell (2011) 2.61
Ubistatins inhibit proteasome-dependent degradation by binding the ubiquitin chain. Science (2004) 2.50
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A positive feedback loop stabilizes the guanine-nucleotide exchange factor Cdc24 at sites of polarization. EMBO J (2002) 2.39
The structure of the CYLD USP domain explains its specificity for Lys63-linked polyubiquitin and reveals a B box module. Mol Cell (2008) 2.27
F-box-directed CRL complex assembly and regulation by the CSN and CAND1. Mol Cell (2009) 2.21
Ubiquitin-related modifier Urm1 acts as a sulphur carrier in thiolation of eukaryotic transfer RNA. Nature (2009) 2.14
The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae. Nature (2005) 2.01
Structurally and functionally unique complexins at retinal ribbon synapses. J Cell Biol (2005) 1.93
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Ubiquitylation-dependent localization of PLK1 in mitosis. Nat Cell Biol (2013) 1.81
Two-sided ubiquitin binding explains specificity of the TAB2 NZF domain. Nat Struct Mol Biol (2009) 1.79
DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-kappaB. EMBO Rep (2009) 1.72
A novel interaction motif, SARAH, connects three classes of tumor suppressor. Curr Biol (2003) 1.69
The MIT domain of UBPY constitutes a CHMP binding and endosomal localization signal required for efficient epidermal growth factor receptor degradation. J Biol Chem (2007) 1.69
Determinants of proteasome recognition of ornithine decarboxylase, a ubiquitin-independent substrate. EMBO J (2003) 1.61
The cytoplasmic Hsp70 chaperone machinery subjects misfolded and endoplasmic reticulum import-incompetent proteins to degradation via the ubiquitin-proteasome system. Mol Biol Cell (2006) 1.61
Yeast homolog of a cancer-testis antigen defines a new transcription complex. EMBO J (2006) 1.58
The zinc finger of the CSN-associated deubiquitinating enzyme USP15 is essential to rescue the E3 ligase Rbx1. Curr Biol (2005) 1.55
Proteasome substrate degradation requires association plus extended peptide. EMBO J (2006) 1.54
Involvement of the ubiquitin-like domain of TBK1/IKK-i kinases in regulation of IFN-inducible genes. EMBO J (2007) 1.51
Rtt101 and Mms1 in budding yeast form a CUL4(DDB1)-like ubiquitin ligase that promotes replication through damaged DNA. EMBO Rep (2008) 1.51
Overexpression of Helicard, a CARD-containing helicase cleaved during apoptosis, accelerates DNA degradation. Curr Biol (2002) 1.50
Prediction of a common structural scaffold for proteasome lid, COP9-signalosome and eIF3 complexes. BMC Bioinformatics (2005) 1.49
Dissection of USP catalytic domains reveals five common insertion points. Mol Biosyst (2009) 1.47
Human Wrnip1 is localized in replication factories in a ubiquitin-binding zinc finger-dependent manner. J Biol Chem (2008) 1.37
Elucidation of ataxin-3 and ataxin-7 function by integrative bioinformatics. Hum Mol Genet (2003) 1.36
Glycine-alanine repeats impair proper substrate unfolding by the proteasome. EMBO J (2006) 1.34
Polyamines regulate their synthesis by inducing expression and blocking degradation of ODC antizyme. EMBO J (2004) 1.32
PCI complexes: Beyond the proteasome, CSN, and eIF3 Troika. Mol Cell (2009) 1.31
A SNARE required for retrograde transport to the endoplasmic reticulum. Proc Natl Acad Sci U S A (2003) 1.31
A common protein interaction domain links two recently identified epilepsy genes. Hum Mol Genet (2002) 1.29
Identification of a new murine tumor necrosis factor receptor locus that contains two novel murine receptors for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). J Biol Chem (2002) 1.29
Comparative analysis of genome sequences of three isolates of Orf virus reveals unexpected sequence variation. Virus Res (2005) 1.27
The Ubx2 and Ubx3 cofactors direct Cdc48 activity to proteolytic and nonproteolytic ubiquitin-dependent processes. Curr Biol (2004) 1.26
SUMO playing tag with ubiquitin. Trends Biochem Sci (2011) 1.26
The human Dcn1-like protein DCNL3 promotes Cul3 neddylation at membranes. Proc Natl Acad Sci U S A (2009) 1.24
Repeat sequence of Epstein-Barr virus-encoded nuclear antigen 1 protein interrupts proteasome substrate processing. J Biol Chem (2003) 1.23
Ubiquitin-independent mechanisms of mouse ornithine decarboxylase degradation are conserved between mammalian and fungal cells. J Biol Chem (2003) 1.23
Slippery substrates impair function of a bacterial protease ATPase by unbalancing translocation versus exit. J Biol Chem (2013) 1.22
RNAi-based screening identifies the Mms22L-Nfkbil2 complex as a novel regulator of DNA replication in human cells. EMBO J (2010) 1.19
Phylogeny and function of the invertebrate p53 superfamily. Cold Spring Harb Perspect Biol (2010) 1.19
Combined characterization of microRNA and mRNA profiles delineates early differentiation pathways of CD133+ and CD34+ hematopoietic stem and progenitor cells. Stem Cells (2011) 1.19
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The yeast GID complex, a novel ubiquitin ligase (E3) involved in the regulation of carbohydrate metabolism. Mol Biol Cell (2008) 1.15
An evolutionarily conserved autoinhibitory molecular switch in ELMO proteins regulates Rac signaling. Curr Biol (2010) 1.15
Ubiquitin-specific protease-like 1 (USPL1) is a SUMO isopeptidase with essential, non-catalytic functions. EMBO Rep (2012) 1.15
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Proteasomes begin ornithine decarboxylase digestion at the C terminus. J Biol Chem (2004) 1.11
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Activating the ubiquitin family: UBA6 challenges the field. Trends Biochem Sci (2008) 1.09
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COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae. EMBO Rep (2002) 1.07
Cullin neddylation and substrate-adaptors counteract SCF inhibition by the CAND1-like protein Lag2 in Saccharomyces cerevisiae. EMBO J (2009) 1.07
The COP9 signalosome-like complex in S. cerevisiae and links to other PCI complexes. Int J Biochem Cell Biol (2003) 1.05
An easily dissociated 26 S proteasome catalyzes an essential ubiquitin-mediated protein degradation pathway in Trypanosoma brucei. J Biol Chem (2002) 1.05
The transmembrane src substrate Trask is an epithelial protein that signals during anchorage deprivation. Am J Pathol (2009) 1.04
TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexes. EMBO J (2013) 1.04
Dependence of proteasome processing rate on substrate unfolding. J Biol Chem (2011) 1.02
Structural elements of antizymes 1 and 2 are required for proteasomal degradation of ornithine decarboxylase. J Biol Chem (2002) 1.02
Functional asymmetries of proteasome translocase pore. J Biol Chem (2012) 1.01
Sumoylation as a signal for polyubiquitylation and proteasomal degradation. Subcell Biochem (2010) 1.00
Urm1 at the crossroad of modifications. 'Protein Modifications: Beyond the Usual Suspects' Review Series. EMBO Rep (2008) 0.98
Highly sensitive profiling of CD44+/CD24- breast cancer stem cells by combining global mRNA amplification and next generation sequencing: evidence for a hyperactive PI3K pathway. Cancer Lett (2012) 0.97
Nicalin and its binding partner Nomo are novel Nodal signaling antagonists. EMBO J (2004) 0.96
Reconfiguration of the proteasome during chaperone-mediated assembly. Nature (2013) 0.96
Structural elements of the ubiquitin-independent proteasome degron of ornithine decarboxylase. Biochem J (2008) 0.95
The yeast E4 ubiquitin ligase Ufd2 interacts with the ubiquitin-like domains of Rad23 and Dsk2 via a novel and distinct ubiquitin-like binding domain. J Biol Chem (2010) 0.95
Long-term cell monitoring of kidney recipients after an antilymphocyte globulin induction with and without steroids. Transplantation (2007) 0.93
eIF2γ mutation that disrupts eIF2 complex integrity links intellectual disability to impaired translation initiation. Mol Cell (2012) 0.92
A mutation in PNPT1, encoding mitochondrial-RNA-import protein PNPase, causes hereditary hearing loss. Am J Hum Genet (2012) 0.91