Published in Neuroscience on January 08, 2008
Chloride extrusion enhancers as novel therapeutics for neurological diseases. Nat Med (2013) 2.00
Chloride regulation in the pain pathway. Brain Res Rev (2008) 1.55
Small-molecule screen identifies inhibitors of the neuronal K-Cl cotransporter KCC2. Proc Natl Acad Sci U S A (2009) 1.45
Neuronal and microglial mechanisms of neuropathic pain. Mol Brain (2011) 1.41
Neurogenic neuroinflammation: inflammatory CNS reactions in response to neuronal activity. Nat Rev Neurosci (2013) 1.24
Spinal cord injury-induced attenuation of GABAergic inhibition in spinal dorsal horn circuits is associated with down-regulation of the chloride transporter KCC2 in rat. J Physiol (2008) 1.20
Modulation of chloride homeostasis by inflammatory mediators in dorsal root ganglion neurons. Mol Pain (2008) 1.11
Microglia control neuronal network excitability via BDNF signalling. Neural Plast (2013) 1.08
A brief comparison of the pathophysiology of inflammatory versus neuropathic pain. Curr Opin Anaesthesiol (2011) 1.08
Physiology of SLC12 transporters: lessons from inherited human genetic mutations and genetically engineered mouse knockouts. Am J Physiol Cell Physiol (2013) 1.01
Novel repression of Kcc2 transcription by REST-RE-1 controls developmental switch in neuronal chloride. J Neurosci (2009) 1.01
Spatial and temporal dynamics in the ionic driving force for GABA(A) receptors. Neural Plast (2011) 1.01
Activity-dependent modulation of glutamatergic signaling in the developing rat dorsal horn by early tissue injury. J Neurophysiol (2009) 0.96
Inhibition of KCC2 in mouse spinal cord neurons leads to hypersensitivity to thermal stimulation. Anesth Analg (2011) 0.95
Further optimization of the K-Cl cotransporter KCC2 antagonist ML077: development of a highly selective and more potent in vitro probe. Bioorg Med Chem Lett (2012) 0.95
Behavioral analysis of Ste20 kinase SPAK knockout mice. Behav Brain Res (2009) 0.95
Vector-mediated release of GABA attenuates pain-related behaviors and reduces Na(V)1.7 in DRG neurons. Eur J Pain (2011) 0.93
Inhibition of carbonic anhydrase augments GABAA receptor-mediated analgesia via a spinal mechanism of action. J Pain (2014) 0.85
Neurogenic and neurotrophic effects of BDNF peptides in mouse hippocampal primary neuronal cell cultures. PLoS One (2013) 0.84
Brain-derived neurotrophic factor-mediated downregulation of brainstem K+-Cl- cotransporter and cell-type-specific GABA impairment for activation of descending pain facilitation. Mol Pharmacol (2013) 0.82
Modulation of spinal GABAergic analgesia by inhibition of chloride extrusion capacity in mice. J Pain (2012) 0.80
Antinociceptive interaction of (±)-CPP and propentofylline in monoarthritic rats. Arthritis Res Ther (2012) 0.80
SNARE-dependent upregulation of potassium chloride co-transporter 2 activity after metabotropic zinc receptor activation in rat cortical neurons in vitro. Neuroscience (2012) 0.79
Therapeutic restoration of spinal inhibition via druggable enhancement of potassium-chloride cotransporter KCC2-mediated chloride extrusion in peripheral neuropathic pain. JAMA Neurol (2014) 0.77
Expanding Spectrum of Sodium Potassium Chloride Co-transporters in the Pathophysiology of Diseases. Curr Neuropharmacol (2015) 0.76
BDNF/TRK/KCC2 pathway in nicotine withdrawal-induced hyperalgesia. Transl Neurosci (2015) 0.75
Analgesic effect of intrathecal bumetanide is accompanied by changes in spinal sodium-potassium-chloride co-transporter 1 and potassium-chloride co-transporter 2 expression in a rat model of incisional pain. Neural Regen Res (2014) 0.75
Combined Changes in Chloride Regulation and Neuronal Excitability Enable Primary Afferent Depolarization to Elicit Spiking without Compromising its Inhibitory Effects. PLoS Comput Biol (2016) 0.75
Participation of central GABAA receptors in the trigeminal processing of mechanical allodynia in rats. Korean J Physiol Pharmacol (2016) 0.75
Motor Cortex Excitability and BDNF Levels in Chronic Musculoskeletal Pain According to Structural Pathology. Front Hum Neurosci (2016) 0.75
The BDNF/TrkB signaling pathway is involved in heat hyperalgesia mediated by Cdk5 in rats. PLoS One (2014) 0.75
Synaptic conversion of chloride-dependent synapses in spinal nociceptive circuits: roles in neuropathic pain. Pain Res Treat (2011) 0.75
Curcumin improves insulin resistance in skeletal muscle of rats. Nutr Metab Cardiovasc Dis (2010) 1.02
Neuroprotection against ischemic brain injury by a small peptide inhibitor of c-Jun N-terminal kinase (JNK) via nuclear and non-nuclear pathways. Neuroscience (2006) 0.97
Distribution of acid-sensing ion channel 3 in the rat hypothalamus. Neuroscience (2009) 0.93
Anti-inflammatory effects of salmeterol/fluticasone, tiotropium/fluticasone or tiotropium in COPD. Eur Respir J (2009) 0.88
320-detector CT coronary angiography with prospective and retrospective electrocardiogram gating in a single heartbeat: comparison of image quality and radiation dose. Br J Radiol (2012) 0.87
Unilateral low-frequency stimulation of central piriform cortex inhibits amygdaloid-kindled seizures in Sprague-Dawley rats. Neuroscience (2007) 0.85
Absence of GABA type A signaling in adult medial habenular neurons. Neuroscience (2006) 0.85
Functional characterization of acid-sensing ion channels in cultured neurons of rat inferior colliculus. Neuroscience (2008) 0.84
Radiological presentation of pulmonary tuberculosis infected by the W-Beijing Mycobacterium tuberculosis strain. Int J Tuberc Lung Dis (2009) 0.84
Ischemic preconditioning negatively regulates plenty of SH3s-mixed lineage kinase 3-Rac1 complex and c-Jun N-terminal kinase 3 signaling via activation of Akt. Neuroscience (2006) 0.83
Mechanisms of modulation of pregnanolone on glycinergic response in cultured spinal dorsal horn neurons of rat. Neuroscience (2006) 0.82
Taurine-evoked chloride current and its potentiation by intracellular Ca2+ in immature rat hippocampal CA1 neurons. Amino Acids (2003) 0.81
Intracellular ASIC1a regulates mitochondrial permeability transition-dependent neuronal death. Cell Death Differ (2013) 0.81
Salicylate, an aspirin metabolite, specifically inhibits the current mediated by glycine receptors containing alpha1-subunits. Br J Pharmacol (2009) 0.79
A pilot study of conformal radiotherapy combined with erlotinib-based multimodality therapy in newly diagnosed metastatic non-small-cell lung cancer. Eur Rev Med Pharmacol Sci (2015) 0.79
Modulation of acid-sensing ion channels by Cu(2+) in cultured hypothalamic neurons of the rat. Neuroscience (2007) 0.79
Chronic subdural hematoma management: clarifying the definitions of outcome measures to better understand treatment efficacy - a systematic review and meta-analysis. Eur Rev Med Pharmacol Sci (2017) 0.75
Detection of common mutations in sporadic primary localized cutaneous amyloidosis by DNA mass spectrometry. Br J Dermatol (2014) 0.75
Upregulation of miR-802 suppresses gastric cancer oncogenicity via targeting RAB23 expression. Eur Rev Med Pharmacol Sci (2017) 0.75