Published in Am J Physiol Heart Circ Physiol on February 08, 2008
How the serotonin story is being rewritten by new gene-based discoveries principally related to SLC6A4, the serotonin transporter gene, which functions to influence all cellular serotonin systems. Neuropharmacology (2008) 1.56
Serotonin and blood pressure regulation. Pharmacol Rev (2012) 1.41
A serotonergic system in veins: serotonin transporter-independent uptake. J Pharmacol Exp Ther (2008) 0.96
A finer tuning of G-protein signaling through regulated control of RGS proteins. Am J Physiol Heart Circ Physiol (2012) 0.91
Lack of the serotonin transporter (SERT) reduces the ability of 5-hydroxytryptamine to lower blood pressure. Naunyn Schmiedebergs Arch Pharmacol (2011) 0.85
Clinical use of antidepressant therapy and associated cardiovascular risk. Drug Healthc Patient Saf (2012) 0.83
Organic cation transporter 3 contributes to norepinephrine uptake into perivascular adipose tissue. Am J Physiol Heart Circ Physiol (2015) 0.81
Gene expression in lungs of mice lacking the 5-hydroxytryptamine transporter gene. BMC Pulm Med (2009) 0.80
Mapping functional brain activation using [14C]-iodoantipyrine in male serotonin transporter knockout mice. PLoS One (2011) 0.79
Lack of the serotonin transporter does not prevent mineralocorticoid hypertension in rat and mouse. Eur J Pharmacol (2008) 0.76
Involvement of organic cation transporter-3 and plasma membrane monoamine transporter in serotonin uptake in human brain vascular smooth muscle cells. Front Pharmacol (2013) 0.76
Comparison of the function of the serotonin transporter in the vasculature of male and female rats. Clin Exp Pharmacol Physiol (2011) 0.76
Habitual coffee consumption and risk of type 2 diabetes, ischemic heart disease, depression and Alzheimer's disease: a Mendelian randomization study. Sci Rep (2016) 0.75
Phosphoinositide 3-kinase mediates enhanced spontaneous and agonist-induced contraction in aorta of deoxycorticosterone acetate-salt hypertensive rats. Circ Res (2002) 1.74
Arterial 5-hydroxytryptamine transporter function is impaired in deoxycorticosterone acetate and Nomega-nitro-L-arginine but not spontaneously hypertensive rats. Hypertension (2006) 1.63
Endothelin-1 increases vascular superoxide via endothelin(A)-NADPH oxidase pathway in low-renin hypertension. Circulation (2003) 1.59
Surviving hilar somatostatin interneurons enlarge, sprout axons, and form new synapses with granule cells in a mouse model of temporal lobe epilepsy. J Neurosci (2009) 1.49
Endothelin receptor function in mesenteric veins from deoxycorticosterone acetate salt-hypertensive rats. J Hypertens (2002) 1.47
Low [Mg2+]e enhances arterial spontaneous tone via phosphatidylinositol 3-kinase in DOCA-salt hypertension. Hypertension (2003) 1.45
Expression of the vitamin d receptor is increased in the hypertrophic heart. Hypertension (2008) 1.33
5-hydroxytryptamine in the cardiovascular system: focus on the serotonin transporter (SERT). Clin Exp Pharmacol Physiol (2006) 1.15
A new signaling paradigm for serotonin: use of Crk-associated substrate in arterial contraction. Am J Physiol Heart Circ Physiol (2006) 1.07
5-Hydroxytryptamine lowers blood pressure in normotensive and hypertensive rats. J Pharmacol Exp Ther (2008) 1.02
Increased O2*- production and upregulation of ETB receptors by sympathetic neurons in DOCA-salt hypertensive rats. Hypertension (2004) 1.02
Chemokines mediate mesenchymal stem cell migration toward gliomas in vitro. Oncol Rep (2010) 1.02
Ypsilandrosides C-G, five new spirostanol saponins from Ypsilandra thibetica. Steroids (2009) 1.01
Chemerin connects fat to arterial contraction. Arterioscler Thromb Vasc Biol (2013) 0.99
Matrix metalloproteinase-9 deficiency phenocopies features of preeclampsia and intrauterine growth restriction. Proc Natl Acad Sci U S A (2013) 0.99
NADPH oxidase-derived superoxide augments endothelin-1-induced venoconstriction in mineralocorticoid hypertension. Hypertension (2003) 0.98
A comparison of arteries and veins in oxidative stress: producers, destroyers, function, and disease. Exp Biol Med (Maywood) (2007) 0.97
A serotonergic system in veins: serotonin transporter-independent uptake. J Pharmacol Exp Ther (2008) 0.96
New 23-spirocholestane derivatives from Ypsilandra thibetica. Planta Med (2013) 0.96
Whole grape intake impacts cardiac peroxisome proliferator-activated receptor and nuclear factor kappaB activity and cytokine expression in rats with diastolic dysfunction. Hypertension (2010) 0.96
Rho/Rho kinase and phosphoinositide 3-kinase are parallel pathways in the development of spontaneous arterial tone in deoxycorticosterone acetate-salt hypertension. J Pharmacol Exp Ther (2004) 0.96
The serotonin transporter is present and functional in peripheral arterial smooth muscle. J Cardiovasc Pharmacol (2004) 0.96
Spirostanol tetraglycosides from Ypsilandra thibetica. Steroids (2010) 0.95
Five new steroidal compounds from Ypsilandra thibetica. Chem Biodivers (2006) 0.95
Peroxisome proliferator-activated receptor-γ agonist 15d-prostaglandin J2 mediates neuronal autophagy after cerebral ischemia-reperfusion injury. PLoS One (2013) 0.95
Dried plasma spots in the diagnosis of tuberculosis: IP-10 release assay on filter paper. Eur Respir J (2013) 0.93
Arteries and veins desensitize differently to endothelin. J Cardiovasc Pharmacol (2004) 0.92
The interdependence of endothelin-1 and calcium: a review. Clin Sci (Lond) (2010) 0.91
Effects of PPAR-gamma ligands on vascular smooth muscle marker expression in hypertensive and normal arteries. Am J Physiol Heart Circ Physiol (2004) 0.90
Vena cava and aortic smooth muscle cells express transglutaminases 1 and 4 in addition to transglutaminase 2. Am J Physiol Heart Circ Physiol (2012) 0.90
Endothelin ET(B) receptors in arteries and veins: multiple actions in the vein. J Pharmacol Exp Ther (2009) 0.90
Upregulation of arterial serotonin 1B and 2B receptors in deoxycorticosterone acetate-salt hypertension. Hypertension (2002) 0.89
Long-term inhibition of xanthine oxidase by febuxostat does not decrease blood pressure in deoxycorticosterone acetate (DOCA)-salt hypertensive rats. PLoS One (2013) 0.89
Knockdown of myostatin expression by RNAi enhances muscle growth in transgenic sheep. PLoS One (2013) 0.89
Onyx embolization for the treatment of brain arteriovenous malformations. Acta Neurochir (Wien) (2010) 0.88
Use of some novel alternative electron sinks to inhibit ruminal methanogenesis. Reprod Nutr Dev (2003) 0.88
PI3-kinase upregulation and involvement in spontaneous tone in arteries from DOCA-salt rats: is p110delta the culprit? Hypertension (2004) 0.88
Drug Delivery: Enabling Technology for Drug Discovery and Development. iPRECIO Micro Infusion Pump: Programmable, Refillable, and Implantable. Front Pharmacol (2011) 0.88
Cyclooxygenase, p38 mitogen-activated protein kinase (MAPK), extracellular signal-regulated kinase MAPK, Rho kinase, and Src mediate hydrogen peroxide-induced contraction of rat thoracic aorta and vena cava. J Pharmacol Exp Ther (2006) 0.88
Arterial expression of 5-HT2B and 5-HT1B receptors during development of DOCA-salt hypertension. BMC Pharmacol (2003) 0.87
Decreased thalamocortical functional connectivity after 36 hours of total sleep deprivation: evidence from resting state FMRI. PLoS One (2013) 0.87
Indoleamine 2,3-diooxygenase in periaortic fat: mechanisms of inhibition of contraction. Am J Physiol Heart Circ Physiol (2011) 0.87
Activation of vascular BK channel by tempol in DOCA-salt hypertensive rats. Hypertension (2005) 0.87
Hepatoprotective role of Ganoderma lucidum polysaccharide against BCG-induced immune liver injury in mice. World J Gastroenterol (2002) 0.87
Characterization of vabicaserin (SCA-136), a selective 5-hydroxytryptamine 2C receptor agonist. J Pharmacol Exp Ther (2011) 0.86
Methyl-beta-cyclodextrin prevents angiotensin II-induced tachyphylactic contractile responses in rat aorta. J Pharmacol Exp Ther (2007) 0.86
Serotonin transporter interacts with the PDGFβ receptor in PDGF-BB-induced signaling and mitogenesis in pulmonary artery smooth muscle cells. Am J Physiol Lung Cell Mol Physiol (2010) 0.86
5-hydroxytryptamine (5-HT) reduces total peripheral resistance during chronic infusion: direct arterial mesenteric relaxation is not involved. BMC Pharmacol (2012) 0.86
Pleiotropic effects of hydrogen peroxide in arteries and veins from normotensive and hypertensive rats. Hypertension (2006) 0.85
Genetic diversity and phylogenetic analysis of glycoprotein GP85 of ALV-J isolates from Mainland China between 1999 and 2010: coexistence of two extremely different subgroups in layers. Vet Microbiol (2011) 0.85
Lack of the serotonin transporter (SERT) reduces the ability of 5-hydroxytryptamine to lower blood pressure. Naunyn Schmiedebergs Arch Pharmacol (2011) 0.85
Upregulated function of phosphatidylinositol-3-kinase in genetically hypertensive rats: a moderator of arterial hypercontractility. Clin Exp Pharmacol Physiol (2005) 0.85
5-Hydroxytryptamine(2B) receptor function is enhanced in the N(omega)-nitro-L-arginine hypertensive rat. J Pharmacol Exp Ther (2002) 0.84
Modification of proteins by norepinephrine is important for vascular contraction. Front Physiol (2010) 0.84
Development and application of real-time PCR for detection of subgroup J avian leukosis virus. J Clin Microbiol (2012) 0.84
One-month serotonin infusion results in a prolonged fall in blood pressure in the deoxycorticosterone acetate (DOCA) salt hypertensive rat. ACS Chem Neurosci (2012) 0.84
Endothelin-1-induced contraction in veins is independent of hydrogen peroxide. Am J Physiol Heart Circ Physiol (2005) 0.84
A comparison of reactive oxygen species metabolism in the rat aorta and vena cava: focus on xanthine oxidase. Am J Physiol Heart Circ Physiol (2008) 0.83
Haemangiomas, leiomyosarcoma and myeloma caused by subgroup J avian leukosis virus in a commercial layer flock. Acta Vet Hung (2010) 0.83
Iron-induced necrotic brain cell death in rats with different aerobic capacity. Transl Stroke Res (2015) 0.83
Body distribution of infused serotonin in rats. Clin Exp Pharmacol Physiol (2009) 0.83
Pharmacological endothelin receptor interaction does not occur in veins from ET(B) receptor deficient rats. Vascul Pharmacol (2008) 0.83
Needle-like Co3O4 anchored on the graphene with enhanced electrochemical performance for aqueous supercapacitors. ACS Appl Mater Interfaces (2014) 0.82
Steroidal saponins with antimicrobial activity from stems and leaves of Paris polyphylla var. yunnanensis. Steroids (2012) 0.82
Temporal changes in the expression of TGF-beta 1 and EGF in the ventral horn of the spinal cord and associated precentral gyrus in adult Rhesus monkeys subjected to cord hemisection. J Neurol Sci (2008) 0.82
Serotonin (5-HT) in veins: not all in vain. J Pharmacol Exp Ther (2007) 0.82
Tigliane-type diterpenoid glycosides from Euphorbia fischeriana. J Nat Prod (2011) 0.81
Role of redox signaling and poly (adenosine diphosphate-ribose) polymerase activation in vascular smooth muscle cell growth inhibition by nitric oxide and peroxynitrite. J Vasc Surg (2008) 0.81
Outcome in adult patients with hemorrhagic moyamoya disease after combined extracranial-intracranial bypass. J Neurosurg (2014) 0.81
Efficacy of extracranial-intracranial revascularization for non-moyamoya steno-occlusive cerebrovascular disease in a series of 66 patients. J Clin Neurosci (2012) 0.81
PI3-kinase-induced hyperreactivity in DOCA-salt hypertension is independent of GSK-3 activity. Hypertension (2003) 0.80
Roles of platelet-derived growth factor-B expression in the ventral horn and motor cortex in the spinal cord-hemisected rhesus monkey. J Neurotrauma (2009) 0.80
Preferential myosin heavy chain isoform B Expression may contribute to the faster velocity of contraction in veins versus arteries. J Vasc Res (2007) 0.80
A potent Brucella abortus 2308 Δery live vaccine allows for the differentiation between natural and vaccinated infection. J Microbiol (2014) 0.80
C(22)-steroidal lactone glycosides from stems and leaves of Paris polyphylla var. yunnanensis. Fitoterapia (2012) 0.80
Steroidal saponins with induced platelet aggregation activity from the aerial parts of Paris verticillata. Steroids (2014) 0.80
Interaction between GABA and norepinephrine in interleukin-1beta-induced suppression of the luteinizing hormone surge. Brain Res (2008) 0.80
Sleeping Beauty-mediated knockdown of sheep myostatin by RNA interference. Biotechnol Lett (2011) 0.80
(+)-Norfenfluramine-induced arterial contraction is not dependent on endogenous 5-hydroxytryptamine or 5-hydroxytryptamine transporter. J Pharmacol Exp Ther (2005) 0.79
The fenfluramine metabolite (+)-norfenfluramine is vasoactive. J Pharmacol Exp Ther (2004) 0.79
bta-miR-29b attenuates apoptosis by directly targeting caspase-7 and NAIF1 and suppresses bovine viral diarrhea virus replication in MDBK cells. Can J Microbiol (2014) 0.79
Endothelin in the splanchnic vascular bed of DOCA-salt hypertensive rats. Am J Physiol Heart Circ Physiol (2004) 0.79
Reverse-mode Na+/Ca2+ exchange is an important mediator of venous contraction. Pharmacol Res (2012) 0.78
Vasoconstriction caused by the ATP synthase subunit-coupling factor 6: a new function for a historical enzyme. Hypertension (2005) 0.78
The cytochrome p450 inhibitor ketoconazole potentiates 5-hydroxytryptamine-induced contraction in rat aorta. J Pharmacol Exp Ther (2007) 0.78
Uric acid does not affect the acetylcholine-induced relaxation of aorta from normotensive and deoxycorticosterone acetate-salt hypertensive rats. J Pharmacol Exp Ther (2010) 0.78
A new neolignan glycoside from the leaves of Acer truncatum. Molecules (2006) 0.78
Cloning, expression and molecular characterization of a 14-3-3 gene from a parasitic ciliate, Cryptocaryon irritans. Vet Parasitol (2013) 0.77
Allopurinol does not decrease blood pressure or prevent the development of hypertension in the deoxycorticosterone acetate-salt rat model. J Cardiovasc Pharmacol (2010) 0.77
Cloning and functional analysis of sheep U6 promoters. Anim Biotechnol (2011) 0.77
Taccasubosides A-D, four new steroidal glycosides from Tacca subflabellata. Steroids (2011) 0.77
Five new withanolides from Tacca plantaginea. Chem Pharm Bull (Tokyo) (2006) 0.77