Metabolic alterations and systemic inflammation in obstructive sleep apnea among nonobese and obese prepubertal children.

PubWeight™: 2.41‹?› | Rank: Top 2%

🔗 View Article (PMC 2383995)

Published in Am J Respir Crit Care Med on February 14, 2008

Authors

David Gozal1, Oscar Sans Capdevila, Leila Kheirandish-Gozal

Author Affiliations

1: Kosair Children's Hospital Research Institute, University of Louisville, 570 South Preston Street, Suite 204, Louisville, KY 40202, USA. david.gozal@louisville.edu

Articles citing this

(truncated to the top 100)

Pathophysiology of sleep apnea. Physiol Rev (2010) 4.69

Upper airway structure and body fat composition in obese children with obstructive sleep apnea syndrome. Am J Respir Crit Care Med (2010) 2.55

Association of adenotonsillectomy with asthma outcomes in children: a longitudinal database analysis. PLoS Med (2014) 2.13

Obstructive sleep apnea in poorly controlled asthmatic children: effect of adenotonsillectomy. Pediatr Pulmonol (2011) 1.72

Is Metabolic Syndrome Associated with Obstructive Sleep Apnea in Obese Adolescents? J Clin Sleep Med (2015) 1.40

Obstructive sleep apnea in children: relative contributions of body mass index and adenotonsillar hypertrophy. Chest (2009) 1.40

Obstructive Sleep Apnea Syndrome is Associated with Metabolic Syndrome among Adolescents and Youth in Beijing: data from Beijing Child and Adolescent Metabolic Syndrome Study. Chin Med J (Engl) (2015) 1.39

Endothelial progenitor cells and vascular dysfunction in children with obstructive sleep apnea. Am J Respir Crit Care Med (2010) 1.32

Intermittent hypoxia exacerbates metabolic effects of diet-induced obesity. Obesity (Silver Spring) (2011) 1.32

Association of short and long sleep durations with insulin sensitivity in adolescents. J Pediatr (2010) 1.27

Obstructive sleep apnea and dyslipidemia: implications for atherosclerosis. Curr Opin Endocrinol Diabetes Obes (2010) 1.27

Obesity in children & adolescents. Indian J Med Res (2010) 1.23

Childhood obesity and obstructive sleep apnea syndrome. J Appl Physiol (1985) (2009) 1.22

Inflammatory pathways in children with insufficient or disordered sleep. Respir Physiol Neurobiol (2011) 1.22

Serum adipocyte fatty acid-binding protein, retinol-binding protein 4, and adiponectin concentrations in relation to the development of the metabolic syndrome in Korean boys: a 3-y prospective cohort study. Am J Clin Nutr (2010) 1.20

Executive summary of respiratory indications for polysomnography in children: an evidence-based review. Sleep (2011) 1.18

Endothelial dysfunction in children without hypertension: potential contributions of obesity and obstructive sleep apnea. Chest (2011) 1.17

Two-dimensional differential in-gel electrophoresis proteomic approaches reveal urine candidate biomarkers in pediatric obstructive sleep apnea. Am J Respir Crit Care Med (2009) 1.13

Metabolic effects of intermittent hypoxia in mice: steady versus high-frequency applied hypoxia daily during the rest period. Am J Physiol Regul Integr Comp Physiol (2012) 1.13

Catecholamines, adiponectin, and insulin resistance as measured by HOMA in children with obstructive sleep apnea. Sleep (2010) 1.07

Childhood obesity and sleep: relatives, partners, or both?--a critical perspective on the evidence. Ann N Y Acad Sci (2012) 1.07

TNF-α gene polymorphisms and excessive daytime sleepiness in pediatric obstructive sleep apnea. J Pediatr (2010) 1.06

Increased cellular proliferation and inflammatory cytokines in tonsils derived from children with obstructive sleep apnea. Pediatr Res (2009) 1.05

The polymorphic and contradictory aspects of intermittent hypoxia. Am J Physiol Lung Cell Mol Physiol (2014) 1.04

Relationship between sleep apnea, fat distribution, and insulin resistance in obese children. J Clin Sleep Med (2011) 1.04

Does sleep duration predict metabolic risk in obese adolescents attending tertiary services? A cross-sectional study. Sleep (2011) 1.01

Adenotonsillectomy in obese children with obstructive sleep apnea syndrome: magnetic resonance imaging findings and considerations. Sleep (2013) 1.00

Obstructive sleep apnea in children: a critical update. Nat Sci Sleep (2013) 1.00

Metabolic and glycemic sequelae of sleep disturbances in children and adults. Curr Diab Rep (2015) 0.99

Endothelial dysfunction in obese non-hypertensive children without evidence of sleep disordered breathing. BMC Pediatr (2010) 0.97

Peripheral blood leukocyte gene expression patterns and metabolic parameters in habitually snoring and non-snoring children with normal polysomnographic findings. Sleep (2011) 0.97

Lipopolysaccharide-binding protein plasma levels in children: effects of obstructive sleep apnea and obesity. J Clin Endocrinol Metab (2013) 0.95

Autonomic cardiovascular tests in children with obstructive sleep apnea syndrome. Sleep (2010) 0.94

The Effect of Adenotonsillectomy for Childhood Sleep Apnea on Cardiometabolic Measures. Sleep (2015) 0.94

Obesity and Altered Sleep: A Pathway to Metabolic Derangements in Children? Semin Pediatr Neurol (2015) 0.94

Endothelial dysfunction in children with obstructive sleep apnea is associated with epigenetic changes in the eNOS gene. Chest (2013) 0.94

Paediatric sleep resources in Canada: The scope of the problem. Paediatr Child Health (2014) 0.92

TREM-1 and pentraxin-3 plasma levels and their association with obstructive sleep apnea, obesity, and endothelial function in children. Sleep (2013) 0.91

Obstructive sleep apnea in obese community-dwelling children: the NANOS study. Sleep (2014) 0.91

Anthropometric and Dental Measurements in Children with Obstructive Sleep Apnea. J Clin Sleep Med (2016) 0.90

Chronic sleep fragmentation induces endothelial dysfunction and structural vascular changes in mice. Sleep (2014) 0.90

Physiological effects of obstructive sleep apnea syndrome in childhood. Respir Physiol Neurobiol (2013) 0.90

Neurocognitive performance and behavior before and after treatment for sleep-disordered breathing in children. Nat Sci Sleep (2010) 0.89

Chemoreceptors, baroreceptors, and autonomic deregulation in children with obstructive sleep apnea. Respir Physiol Neurobiol (2012) 0.88

A mixed cell culture model for assessment of proliferation in tonsillar tissues from children with obstructive sleep apnea or recurrent tonsillitis. Laryngoscope (2009) 0.88

Obstructive sleep apnea syndrome: natural history, diagnosis, and emerging treatment options. Nat Sci Sleep (2010) 0.87

Sleep problems in urban, minority, early-school-aged children more prevalent than previously recognized. Clin Pediatr (Phila) (2013) 0.86

Transcriptomic analysis identifies phosphatases as novel targets for adenotonsillar hypertrophy of pediatric obstructive sleep apnea. Am J Respir Crit Care Med (2010) 0.86

Fatty-acid binding protein 4 gene polymorphisms and plasma levels in children with obstructive sleep apnea. Sleep Med (2011) 0.86

Habitual snoring in school-aged children: environmental and biological predictors. Respir Res (2010) 0.86

Role of sleep quality in the metabolic syndrome. Diabetes Metab Syndr Obes (2016) 0.86

Impact of Adenotonsillectomy on Insulin Resistance and Lipoprotein Profile in Nonobese and Obese Children. Chest (2016) 0.85

Variants in C-reactive protein and IL-6 genes and susceptibility to obstructive sleep apnea in children: a candidate-gene association study in European American and Southeast European populations. Sleep Med (2013) 0.85

Childhood obesity and obstructive sleep apnea. J Nutr Metab (2012) 0.85

Genotype-phenotype interactions in pediatric obstructive sleep apnea. Respir Physiol Neurobiol (2013) 0.85

A brief primer on sleep for pediatric and child clinical neuropsychologists. Child Neuropsychol (2011) 0.84

Current treatment of selected pediatric sleep disorders. Neurotherapeutics (2012) 0.84

Tumor circulating DNA profiling in xenografted mice exposed to intermittent hypoxia. Oncotarget (2015) 0.84

Effects of adenotonsillectomy on plasma inflammatory biomarkers in obese children with obstructive sleep apnea: A community-based study. Int J Obes (Lond) (2015) 0.84

The underlying interactome of childhood obesity: the potential role of sleep. Child Obes (2012) 0.82

Vitamin D levels and obstructive sleep apnoea in children. Sleep Med (2014) 0.82

Inefficient or insufficient encoding as potential primary deficit in neurodevelopmental performance among children with OSA. Dev Neuropsychol (2009) 0.82

Increased systemic inflammation overnight correlates with insulin resistance among children evaluated for obstructive sleep apnea. Sleep Breath (2011) 0.81

Effects of adenoidectomy on markers of endothelial function and inflammation in normal-weight and overweight prepubescent children with sleep apnea. J Res Med Sci (2011) 0.81

Inflammatory markers and obstructive sleep apnea in obese children: the NANOS study. Mediators Inflamm (2014) 0.81

Biological plausibility linking sleep apnoea and metabolic dysfunction. Nat Rev Endocrinol (2016) 0.81

Polymorphisms in nitric oxide synthase and endothelin genes among children with obstructive sleep apnea. BMC Med Genomics (2013) 0.80

Craniofacial syndromes and sleep-related breathing disorders. Sleep Med Rev (2015) 0.80

Obstructive sleep apnea and asthma. J Bras Pneumol (2013) 0.79

Mr. Pickwick and his child went on a field trip and returned almost empty handed...What we do not know and imperatively need to learn about obesity and breathing during sleep in children! Sleep Med Rev (2008) 0.79

Acute sleep fragmentation induces tissue-specific changes in cytokine gene expression and increases serum corticosterone concentration. Am J Physiol Regul Integr Comp Physiol (2015) 0.79

Sleep, sleep-disordered breathing and lipid homeostasis: translational evidence from murine models and children. Clin Lipidol (2012) 0.79

Resveratrol attenuates intermittent hypoxia-induced macrophage migration to visceral white adipose tissue and insulin resistance in male mice. Endocrinology (2014) 0.79

Sleep: important considerations for the prevention of cardiovascular disease. Curr Opin Cardiol (2016) 0.79

Obesity in children with different risk factors for obstructive sleep apnea: a community-based study. Eur J Pediatr (2015) 0.78

Growth after adenotonsillectomy for obstructive sleep apnea: an RCT. Pediatrics (2014) 0.78

The use of sub-mental ultrasonography for identifying patients with severe obstructive sleep apnea. PLoS One (2013) 0.78

Treatment alternatives for sleep-disordered breathing in the pediatric population. Curr Opin Pulm Med (2008) 0.78

Guidelines for diagnosing and treating sleep related breathing disorders in adults and children (Part 3: obstructive sleep apnea in children, diagnosis and treatment). Hippokratia (2010) 0.78

Pediatric OSAS Morbidity Biomarkers: The Hunt is Finally On! Chest (2016) 0.78

Perinatal Risk Factors Associated with the Obstructive Sleep Apnea Syndrome in School-Aged Children Born Preterm. Sleep (2016) 0.78

Insulin Resistance and Hypertension in Obese Youth With Sleep-Disordered Breathing Treated With Positive Airway Pressure: A Prospective Multicenter Study. J Clin Sleep Med (2017) 0.78

Respiratory cortical processing to inspiratory resistances during wakefulness in children with the obstructive sleep apnea syndrome. J Appl Physiol (1985) (2014) 0.77

Contextualised urinary biomarker analysis facilitates diagnosis of paediatric obstructive sleep apnoea. Sleep Med (2014) 0.77

Macrophage migration inhibitory factor gene polymorphisms and plasma levels in children with obstructive sleep apnea. Pediatr Pulmonol (2012) 0.77

Update on paediatric obstructive sleep apnoea. J Thorac Dis (2016) 0.77

Obstructive sleep apnea and obesity are associated with reduced GPR 120 plasma levels in children. Sleep (2014) 0.77

The Endothelium as a Target in Pediatric OSA. Front Neurol (2012) 0.77

Influence of obesity on nocturnal oxygen saturation in young children. Eur J Pediatr (2012) 0.75

Sleep-disordered breathing in children with asthma: a systematic review on the impact of treatment. J Asthma Allergy (2016) 0.75

When it Comes to Children, Are We Really that Cautious? J Clin Sleep Med (2015) 0.75

Metabolic disease in sleep disordered breathing: puberty! puberty! Sleep (2010) 0.75

Utilizing inspiratory airflows during standard polysomnography to assess pharyngeal function in children during sleep. Pediatr Pulmonol (2015) 0.75

Indications for tonsillectomy stratified by the level of evidence. GMS Curr Top Otorhinolaryngol Head Neck Surg (2016) 0.75

Biomarkers of Alzheimer Disease in Children with Obstructive Sleep Apnea: Effect of Adenotonsillectomy. Sleep (2016) 0.75

Pupillometric findings in children with obstructive sleep apnea. Sleep Med (2015) 0.75

Metabolic consequences of snoring in adolescents and younger adults: a population study in Chile. Int J Obes (Lond) (2016) 0.75

Endothelial Dysfunction in Children With Obstructive Sleep Apnea Is Associated With Elevated Lipoprotein-Associated Phospholipase A2 Plasma Activity Levels. J Am Heart Assoc (2017) 0.75

PAP Therapy's Effect on Cardiometabolic Risk Markers in Pediatric Patients. J Clin Sleep Med (2017) 0.75

Effect of Obstructive Sleep Apnea Treatment on Lipids in Obese Children. Children (Basel) (2017) 0.75

Articles cited by this

CDC growth charts: United States. Adv Data (2000) 38.32

EEG arousals: scoring rules and examples: a preliminary report from the Sleep Disorders Atlas Task Force of the American Sleep Disorders Association. Sleep (1992) 11.58

The relation of overweight to cardiovascular risk factors among children and adolescents: the Bogalusa Heart Study. Pediatrics (1999) 11.20

Adipocytes as regulators of energy balance and glucose homeostasis. Nature (2006) 9.52

Mechanisms linking obesity with cardiovascular disease. Nature (2006) 9.07

Adrenocortical, autonomic, and inflammatory causes of the metabolic syndrome: nested case-control study. Circulation (2002) 3.63

Polysomnographic characteristics in normal preschool and early school-aged children. Pediatrics (2006) 3.27

Effects of continuous positive airway pressure on early signs of atherosclerosis in obstructive sleep apnea. Am J Respir Crit Care Med (2007) 3.07

Predictability of childhood adiposity and insulin for developing insulin resistance syndrome (syndrome X) in young adulthood: the Bogalusa Heart Study. Diabetes (2002) 2.89

Association between inadequate sleep and insulin resistance in obese children. J Pediatr (2007) 2.76

Intermittent hypoxia increases insulin resistance in genetically obese mice. J Physiol (2003) 2.71

Sleep and neurobehavioral characteristics of 5- to 7-year-old children with parentally reported symptoms of attention-deficit/hyperactivity disorder. Pediatrics (2003) 2.69

Persistence of obstructive sleep apnea syndrome in children after adenotonsillectomy. J Pediatr (2006) 2.57

Hyperlipidemia and lipid peroxidation are dependent on the severity of chronic intermittent hypoxia. J Appl Physiol (1985) (2006) 2.39

Twenty-four-hour ambulatory blood pressure in children with sleep-disordered breathing. Am J Respir Crit Care Med (2004) 2.34

Fasting insulin and apolipoprotein B levels and low-density lipoprotein particle size as risk factors for ischemic heart disease. JAMA (1998) 2.28

Intermittent hypoxia induces hyperlipidemia in lean mice. Circ Res (2005) 2.21

Metabolic correlates with obstructive sleep apnea in obese subjects. J Pediatr (2002) 2.16

Apolipoprotein B: a clinically important apolipoprotein which assembles atherogenic lipoproteins and promotes the development of atherosclerosis. J Intern Med (2005) 2.14

Chronic intermittent hypoxia upregulates genes of lipid biosynthesis in obese mice. J Appl Physiol (1985) (2005) 2.09

Intermittent hypoxia causes insulin resistance in lean mice independent of autonomic activity. Am J Respir Crit Care Med (2007) 2.09

Relationship between insulin resistance and abnormal lipid profile in obese adolescents. J Pediatr (1995) 2.06

Variation of C-reactive protein levels in adolescents: association with sleep-disordered breathing and sleep duration. Circulation (2005) 1.99

Association between metabolic syndrome and sleep-disordered breathing in adolescents. Am J Respir Crit Care Med (2007) 1.98

Changes in intra-abdominal visceral fat and serum leptin levels in patients with obstructive sleep apnea syndrome following nasal continuous positive airway pressure therapy. Circulation (1999) 1.90

Snoring and sleep-disordered breathing in young children: subjective and objective correlates. Sleep (2004) 1.90

Plasma C-reactive protein levels among children with sleep-disordered breathing. Pediatrics (2004) 1.88

Blood pressure in children with obstructive sleep apnea. Am J Respir Crit Care Med (1998) 1.79

Obstructive sleep-disordered breathing and fasting insulin levels in nonobese children. Pediatr Pulmonol (2005) 1.70

C-reactive protein, obstructive sleep apnea, and cognitive dysfunction in school-aged children. Am J Respir Crit Care Med (2007) 1.68

Outcome of adenotonsillectomy for obstructive sleep apnea in obese and normal-weight children. Otolaryngol Head Neck Surg (2007) 1.64

Effects of exercise training and its cessation on components of the insulin resistance syndrome in obese children. Int J Obes Relat Metab Disord (1999) 1.64

Systemic inflammation in non-obese children with obstructive sleep apnea. Sleep Med (2007) 1.58

Persistent elevation of plasma insulin levels is associated with increased cardiovascular risk in children and young adults. The Bogalusa Heart Study. Circulation (1996) 1.54

Obstructive sleep apnea and endothelial function in school-aged nonobese children: effect of adenotonsillectomy. Circulation (2007) 1.54

Apolipoprotein A-I and B levels and the risk of ischemic heart disease during a five-year follow-up of men in the Québec cardiovascular study. Circulation (1996) 1.54

Child overweight and obesity in the USA: prevalence rates according to IOTF definitions. Int J Pediatr Obes (2007) 1.51

Determinants of early atherosclerosis in obese children and adolescents. J Clin Endocrinol Metab (2007) 1.42

Sleep-disordered breathing in 3,680 Greek children. Pediatr Pulmonol (2004) 1.41

HDL dysfunction in obstructive sleep apnea. Atherosclerosis (2005) 1.33

Insulin resistance: cellular and clinical concepts. Exp Biol Med (Maywood) (2001) 1.33

Obesity rather than severity of sleep-disordered breathing as the major determinant of insulin resistance and altered lipidemia in snoring children. Pediatrics (2005) 1.32

Aerobic fitness attenuates the metabolic syndrome score in normal-weight, at-risk-for-overweight, and overweight children. Pediatrics (2007) 1.32

Autonomic dysfunction in children with sleep-disordered breathing. Sleep (2005) 1.31

Television, computer use, physical activity, diet and fatness in Australian adolescents. Int J Pediatr Obes (2006) 1.30

Plasma C-reactive protein in nonobese children with obstructive sleep apnea before and after adenotonsillectomy. J Clin Sleep Med (2006) 1.29

Heart rate variability in children with obstructive sleep apnea. Sleep (1997) 1.27

Blood pressure elevation associated with sleep-related breathing disorder in a community sample of white and Hispanic children: the Tucson Children's Assessment of Sleep Apnea study. Arch Pediatr Adolesc Med (2003) 1.26

Sleep-disordered breathing and the metabolic syndrome in overweight and obese children and adolescents. J Pediatr (2007) 1.21

Hypoxemia and obesity modulate plasma C-reactive protein and interleukin-6 levels in sleep-disordered breathing. Sleep Breath (2007) 1.17

Plasma adhesion molecules in children with sleep-disordered breathing. Chest (2006) 1.13

Left ventricular function in children with sleep-disordered breathing. Am J Cardiol (2005) 1.10

Adipokines in children with sleep disordered breathing. Sleep (2007) 1.08

Movement/arousals. Description, classification, and relationship to sleep apnea in children. Am J Respir Crit Care Med (1994) 1.07

Follow-up on metabolic markers in children treated for obstructive sleep apnea. Am J Respir Crit Care Med (2006) 1.04

Apolipoprotein B and AI distributions in the United States, 1988-1991: results of the National Health and Nutrition Examination Survey III (NHANES III). Clin Chem (1997) 1.04

Insulin and obstructive sleep apnea in obese Chinese children. Pediatr Pulmonol (2006) 0.99

Pediatric reference intervals for lipids and apolipoproteins on the VITROS 5,1 FS Chemistry System. Clin Biochem (2006) 0.97

The German study on sleep-disordered breathing in primary school children: epidemiological approach, representativeness of study sample, and preliminary screening results. Paediatr Perinat Epidemiol (2004) 0.95

Worldwide distribution of blood lipids and lipoproteins in childhood and adolescence: a review study. Atherosclerosis (1998) 0.91

The development of snoring and sleep related breathing distress from 4 to 6 years in a cohort of Swedish children. Int J Pediatr Otorhinolaryngol (2007) 0.88

Multidimensional scaling of pediatric sleep breathing problems and bio-behavioral correlates. Sleep Med (2006) 0.88

Symptoms of sleep breathing disorders in children are underreported by parents at general practice visits. Sleep Breath (2003) 0.83

Serum apolipoprotein A1, B, CII, CIII, E, and lipoprotein (a) levels in children. Clin Biochem (1996) 0.81

Articles by these authors

Adenotonsillectomy outcomes in treatment of obstructive sleep apnea in children: a multicenter retrospective study. Am J Respir Crit Care Med (2010) 3.69

Cardiovascular morbidity in obstructive sleep apnea: oxidative stress, inflammation, and much more. Am J Respir Crit Care Med (2007) 2.62

DNA methylation in inflammatory genes among children with obstructive sleep apnea. Am J Respir Crit Care Med (2011) 1.92

C-reactive protein, obstructive sleep apnea, and cognitive dysfunction in school-aged children. Am J Respir Crit Care Med (2007) 1.68

Systemic inflammation in non-obese children with obstructive sleep apnea. Sleep Med (2007) 1.58

Plasma IGF-1 levels and cognitive dysfunction in children with obstructive sleep apnea. Sleep Med (2008) 1.57

Obstructive sleep apnea and endothelial function in school-aged nonobese children: effect of adenotonsillectomy. Circulation (2007) 1.54

Pediatric obstructive sleep apnea: complications, management, and long-term outcomes. Proc Am Thorac Soc (2008) 1.52

Diagnosis and management of restless legs syndrome in children. Sleep Med Rev (2009) 1.49

Neurocognitive and behavioral morbidity in children with sleep disorders. Curr Opin Pulm Med (2007) 1.41

Obstructive sleep apnea in children: relative contributions of body mass index and adenotonsillar hypertrophy. Chest (2009) 1.40

Cardiovascular complications of obstructive sleep apnea syndrome: evidence from children. Prog Cardiovasc Dis (2009) 1.31

Plasma C-reactive protein in nonobese children with obstructive sleep apnea before and after adenotonsillectomy. J Clin Sleep Med (2006) 1.29

Childhood Obstructive Sleep Apnea: One or Two Distinct Disease Entities? Sleep Med Clin (2007) 1.24

APOE epsilon 4 allele, cognitive dysfunction, and obstructive sleep apnea in children. Neurology (2007) 1.23

Inflammatory pathways in children with insufficient or disordered sleep. Respir Physiol Neurobiol (2011) 1.22

Obesity and obstructive sleep apnea syndrome in children: a tale of inflammatory cascades. Pediatr Pulmonol (2010) 1.19

Obesity and excessive daytime sleepiness in prepubertal children with obstructive sleep apnea. Pediatrics (2009) 1.18

Endothelial dysfunction in children without hypertension: potential contributions of obesity and obstructive sleep apnea. Chest (2011) 1.17

Genome-wide gene expression profiling in children with non-obese obstructive sleep apnea. Sleep Med (2008) 1.16

Prevalence of epileptiform activity in healthy children during sleep. Sleep Med (2007) 1.15

Neurocognitive and endothelial dysfunction in children with obstructive sleep apnea. Pediatrics (2010) 1.14

Two-dimensional differential in-gel electrophoresis proteomic approaches reveal urine candidate biomarkers in pediatric obstructive sleep apnea. Am J Respir Crit Care Med (2009) 1.13

Sleep measures and morning plasma TNF-alpha levels in children with sleep-disordered breathing. Sleep (2010) 1.11

Leukotriene pathways and in vitro adenotonsillar cell proliferation in children with obstructive sleep apnea. Chest (2008) 1.11

Adipokines in children with sleep disordered breathing. Sleep (2007) 1.08

Childhood obesity and sleep: relatives, partners, or both?--a critical perspective on the evidence. Ann N Y Acad Sci (2012) 1.07

TNF-α gene polymorphisms and excessive daytime sleepiness in pediatric obstructive sleep apnea. J Pediatr (2010) 1.06

Increased cellular proliferation and inflammatory cytokines in tonsils derived from children with obstructive sleep apnea. Pediatr Res (2009) 1.05

Circulating adropin concentrations in pediatric obstructive sleep apnea: potential relevance to endothelial function. J Pediatr (2013) 1.05

Dietary and physical activity patterns in children with obstructive sleep apnea. J Pediatr (2010) 1.03

Obstructive sleep apnea in children: a critical update. Nat Sci Sleep (2013) 1.00

Sympathetic and catecholaminergic alterations in sleep apnea with particular emphasis on children. Front Neurol (2012) 0.99

Algorithm for the diagnosis and treatment of pediatric OSA: a proposal of two pediatric sleep centers. Sleep Med (2012) 0.97

Endothelial dysfunction in obese non-hypertensive children without evidence of sleep disordered breathing. BMC Pediatr (2010) 0.97

New approaches to the diagnosis of sleep-disordered breathing in children. Sleep Med (2010) 0.97

Increased morning brain natriuretic peptide levels in children with nocturnal enuresis and sleep-disordered breathing: a community-based study. Pediatrics (2008) 0.97

Peripheral blood leukocyte gene expression patterns and metabolic parameters in habitually snoring and non-snoring children with normal polysomnographic findings. Sleep (2011) 0.97

Leukocyte telomere length and plasma catestatin and myeloid-related protein 8/14 concentrations in children with obstructive sleep apnea. Chest (2010) 0.97

The multiple challenges of obstructive sleep apnea in children: morbidity and treatment. Curr Opin Pediatr (2008) 0.96

Insulin sensitivity, serum lipids, and systemic inflammatory markers in school-aged obese and nonobese children. Int J Pediatr (2011) 0.95

C-reactive protein and obstructive sleep apnea syndrome in children. Front Biosci (Elite Ed) (2012) 0.94

Alterations in circulating T-cell lymphocyte populations in children with obstructive sleep apnea. Sleep (2013) 0.94

Cognitive function in prepubertal children with obstructive sleep apnea: a modifying role for NADPH oxidase p22 subunit gene polymorphisms? Antioxid Redox Signal (2011) 0.93

Catecholamine alterations in pediatric obstructive sleep apnea: effect of obesity. Pediatr Pulmonol (2009) 0.92

Fatty-acid binding protein 4 gene variants and childhood obesity: potential implications for insulin sensitivity and CRP levels. Lipids Health Dis (2010) 0.92

TREM-1 and pentraxin-3 plasma levels and their association with obstructive sleep apnea, obesity, and endothelial function in children. Sleep (2013) 0.91

The obesity epidemic and disordered sleep during childhood and adolescence. Adolesc Med State Art Rev (2010) 0.91

Nocturnal body position in sleeping children with and without obstructive sleep apnea. Pediatr Pulmonol (2007) 0.90

Chemoreceptors, baroreceptors, and autonomic deregulation in children with obstructive sleep apnea. Respir Physiol Neurobiol (2012) 0.88

A mixed cell culture model for assessment of proliferation in tonsillar tissues from children with obstructive sleep apnea or recurrent tonsillitis. Laryngoscope (2009) 0.88

Fatty-acid binding protein 4 gene polymorphisms and plasma levels in children with obstructive sleep apnea. Sleep Med (2011) 0.86

Transcriptomic analysis identifies phosphatases as novel targets for adenotonsillar hypertrophy of pediatric obstructive sleep apnea. Am J Respir Crit Care Med (2010) 0.86

Neurotrophins and tonsillar hypertrophy in children with obstructive sleep apnea. Pediatr Res (2007) 0.85

The promise of translational and personalised approaches for paediatric obstructive sleep apnoea: an 'Omics' perspective. Thorax (2014) 0.84

Nocturnal polysomnographic characteristics of habitually snoring children initially referred to pediatric ENT or sleep clinics. Sleep Med (2009) 0.84

Obesity, asthma, and sleep-disordered breathing. J Pediatr (2011) 0.84

Monocarboxylate transporter 2 and stroke severity in a rodent model of sleep apnea. J Neurosci (2011) 0.83

Uric acid excretion in North American and Southeast European children with obstructive sleep apnea. Sleep Med (2010) 0.83

Prevalence of recurrent otitis media in habitually snoring school-aged children. Sleep Med (2007) 0.83

Adherence to reduced-polluting biomass fuel stoves improves respiratory and sleep symptoms in children. BMC Pediatr (2014) 0.83

Fat and lymphadenoid tissues: a mutually obstructive combination. Am J Respir Crit Care Med (2011) 0.82

Inefficient or insufficient encoding as potential primary deficit in neurodevelopmental performance among children with OSA. Dev Neuropsychol (2009) 0.82

Effect of reductions in biomass fuel exposure on symptoms of sleep apnea in children living in the peruvian andes: a preliminary field study. Pediatr Pulmonol (2012) 0.80

Polymorphisms in nitric oxide synthase and endothelin genes among children with obstructive sleep apnea. BMC Med Genomics (2013) 0.80

Pediatric Home Sleep Apnea Testing: Slowly Getting There! Chest (2015) 0.79

T regulatory lymphocytes and endothelial function in pediatric obstructive sleep apnea. PLoS One (2013) 0.79

Genetic variance in nitric oxide synthase and endothelin genes among children with and without endothelial dysfunction. J Transl Med (2013) 0.79

Iron deficiency and periodic leg movement disorder of sleep. Sleep Med (2008) 0.78

Macrophage migration inhibitory factor gene polymorphisms and plasma levels in children with obstructive sleep apnea. Pediatr Pulmonol (2012) 0.77

Reliability of home respiratory polygraphy for the diagnosis of sleep apnea in children. Chest (2015) 0.77

Pediatric obstructive sleep apnea: a potential late consequence of respiratory syncitial virus bronchiolitis. Pediatr Pulmonol (2009) 0.77

Sleep-disordered breathing and verbal skills in school-aged community children. Dev Neuropsychol (2009) 0.76

Eye movement during REM sleep in children with attention deficit hyperactivity disorder. Dev Neuropsychol (2009) 0.76

Sleep apnea in children--treatment considerations. Paediatr Respir Rev (2006) 0.76

The injury theory, endothelial progenitors, and sleep apnea. Am J Respir Crit Care Med (2013) 0.75

Response. Chest (2014) 0.75

Automated analysis of nocturnal oximetry as screening tool for childhood obstructive sleep apnea-hypopnea syndrome. Conf Proc IEEE Eng Med Biol Soc (2015) 0.75

Substance P and neurokinin 1 receptors as potential therapeutic targets in children with OSA. Chest (2014) 0.75

Home sleep testing for the diagnosis of pediatric obstructive sleep apnea: the times they are a changing …! Curr Opin Pulm Med (2015) 0.75

Analysis and classification of oximetry recordings to predict obstructive sleep apnea severity in children. Conf Proc IEEE Eng Med Biol Soc (2015) 0.75

Usefulness of discrete wavelet transform in the analysis of oximetry signals to assist in childhood sleep apnea-hypopnea syndrome diagnosis. Conf Proc IEEE Eng Med Biol Soc (2017) 0.75