Published in Cell Microbiol on February 19, 2008
Quantification of the infectious dose of Leishmania major transmitted to the skin by single sand flies. Proc Natl Acad Sci U S A (2008) 1.98
Leishmania development in sand flies: parasite-vector interactions overview. Parasit Vectors (2012) 1.52
Leishmania sand fly interaction: progress and challenges. Curr Opin Microbiol (2008) 1.30
Experimental transmission of Leishmania infantum by two major vectors: a comparison between a viscerotropic and a dermotropic strain. PLoS Negl Trop Dis (2011) 1.07
Peritrophic matrix of Phlebotomus duboscqi and its kinetics during Leishmania major development. Cell Tissue Res (2009) 1.05
The role of leishmania proteophosphoglycans in sand fly transmission and infection of the Mammalian host. Front Microbiol (2012) 1.03
Inhibition of trypsin expression in Lutzomyia longipalpis using RNAi enhances the survival of Leishmania. Parasit Vectors (2009) 1.03
Proteophosophoglycans regurgitated by Leishmania-infected sand flies target the L-arginine metabolism of host macrophages to promote parasite survival. PLoS Pathog (2009) 1.01
Proteophosphoglycan confers resistance of Leishmania major to midgut digestive enzymes induced by blood feeding in vector sand flies. Cell Microbiol (2010) 0.99
Stage-specific adhesion of Leishmania promastigotes to sand fly midguts assessed using an improved comparative binding assay. PLoS Negl Trop Dis (2010) 0.98
Evidence that intracellular stages of Leishmania major utilize amino sugars as a major carbon source. PLoS Pathog (2010) 0.97
The importance of chitin in the marine environment. Mar Biotechnol (NY) (2011) 0.96
Colonisation resistance in the sand fly gut: Leishmania protects Lutzomyia longipalpis from bacterial infection. Parasit Vectors (2014) 0.96
Targeting the midgut secreted PpChit1 reduces Leishmania major development in its natural vector, the sand fly Phlebotomus papatasi. PLoS Negl Trop Dis (2010) 0.94
Sand fly-Leishmania interactions: long relationships are not necessarily easy. Open Parasitol J (2010) 0.92
Bacterial feeding, Leishmania infection and distinct infection routes induce differential defensin expression in Lutzomyia longipalpis. Parasit Vectors (2013) 0.92
The effects of ingested mammalian blood factors on vector arthropod immunity and physiology. Microbes Infect (2013) 0.91
An investigation into the protein composition of the teneral Glossina morsitans morsitans peritrophic matrix. PLoS Negl Trop Dis (2014) 0.88
Characterization of Phlebotomus papatasi peritrophins, and the role of PpPer1 in Leishmania major survival in its natural vector. PLoS Negl Trop Dis (2013) 0.86
Mammalian African trypanosome VSG coat enhances tsetse's vector competence. Proc Natl Acad Sci U S A (2016) 0.82
Perpetuation of Leishmania: some novel insight into elegant developmental programs. Vet Res (2009) 0.81
Ecotin-like serine peptidase inhibitor ISP1 of Leishmania major plays a role in flagellar pocket dynamics and promastigote differentiation. Cell Microbiol (2012) 0.78
The flagellar protein FLAG1/SMP1 is a candidate for Leishmania-sand fly interaction. Vector Borne Zoonotic Dis (2015) 0.78
Leishmania donovani development in Phlebotomus argentipes: comparison of promastigote- and amastigote-initiated infections. Parasitology (2016) 0.77
VSG overcomes an early barrier to survival of African trypanosomes in tsetse flies. Proc Natl Acad Sci U S A (2016) 0.76
An integrated overview of the midgut bacterial flora composition of Phlebotomus perniciosus, a vector of zoonotic visceral leishmaniasis in the Western Mediterranean Basin. PLoS Negl Trop Dis (2017) 0.75
Experimental infection and transmission of Leishmania by Lutzomyia cruzi (Diptera: Psychodidae): Aspects of the ecology of parasite-vector interactions. PLoS Negl Trop Dis (2017) 0.75
Recombinant Forms of Leishmania amazonensis Excreted/Secreted Promastigote Surface Antigen (PSA) Induce Protective Immune Responses in Dogs. PLoS Negl Trop Dis (2016) 0.75
Identification of an infective stage of Leishmania promastigotes. Science (1984) 4.00
Peritrophic matrix structure and function. Annu Rev Entomol (1997) 2.57
Transmission of cutaneous leishmaniasis by sand flies is enhanced by regurgitation of fPPG. Nature (2004) 2.36
Phlebotomine sand flies and Leishmania parasites: friends or foes? Trends Parasitol (2006) 2.27
Molecular aspects of parasite-vector and vector-host interactions in leishmaniasis. Annu Rev Microbiol (2001) 2.23
The role of promastigote secretory gel in the origin and transmission of the infective stage of Leishmania mexicana by the sandfly Lutzomyia longipalpis. Parasitology (2002) 2.04
Leishmania manipulation of sand fly feeding behavior results in enhanced transmission. PLoS Pathog (2007) 1.72
Sand flies and Leishmania: specific versus permissive vectors. Trends Parasitol (2007) 1.47
Complete developmental cycle of Leishmania mexicana in axenic culture. Parasitology (1994) 1.44
A novel role for the peritrophic matrix in protecting Leishmania from the hydrolytic activities of the sand fly midgut. Parasitology (1997) 1.43
Knockout of the rodent malaria parasite chitinase pbCHT1 reduces infectivity to mosquitoes. Infect Immun (2001) 1.41
Two separate growth phases during the development of Leishmania in sand flies: implications for understanding the life cycle. Int J Parasitol (2003) 1.39
New insights into the developmental biology and transmission mechanisms of Leishmania. Curr Mol Med (2004) 1.38
Leishmania infections damage the feeding mechanism of the sandfly vector and implement parasite transmission by bite. Proc Natl Acad Sci U S A (1992) 1.36
Chitinase secreted by Leishmania functions in the sandfly vector. Proc Biol Sci (1991) 1.30
Filamentous proteophosphoglycan secreted by Leishmania promastigotes forms gel-like three-dimensional networks that obstruct the digestive tract of infected sandfly vectors. Eur J Cell Biol (1999) 1.24
Development of different Leishmania major strains in the vector sandflies Phlebotomus papatasi and P. duboscqi. Ann Trop Med Parasitol (1997) 1.23
Characterization of a blood activated chitinolytic system in the midgut of the sand fly vectors Lutzomyia longipalpis and Phlebotomus papatasi. Insect Mol Biol (2005) 1.20
Blocked stomodeal valve of the insect vector: similar mechanism of transmission in two trypanosomatid models. Int J Parasitol (2004) 1.18
Leishmania differentiation in natural and unnatural sand fly hosts. J Eukaryot Microbiol (1993) 1.17
Dissection of the functional domains of the Leishmania surface membrane 3'-nucleotidase/nuclease, a unique member of the class I nuclease family. J Biol Chem (2000) 1.13
Fluid mechanics of bloodmeal uptake by Leishmania-infected sandflies. Acta Trop (1986) 1.01
Ultrastructural development of Leishmania chagasi in its vector, Lutzomyia longipalpis (Diptera: Psychodidae). Am J Trop Med Hyg (1989) 1.01
Molecular characterization, expression, and in vivo analysis of LmexCht1: the chitinase of the human pathogen, Leishmania mexicana. J Biol Chem (2004) 0.99
Lutzomyia longipalpis peritrophic matrix: formation, structure, and chemical composition. J Med Entomol (2005) 0.94
Abortive infection of Lutzomyia longipalpis insect vectors by aflagellated LdARL-3A-Q70L overexpressing Leishmania amazonensis parasites. Cell Microbiol (2003) 0.94
The Ld Cht1 gene encodes the secretory chitinase of the human pathogen Leishmania donovani. Gene (1998) 0.92
The developmental biology of Leishmania promastigotes. Exp Parasitol (1994) 0.92
Pathogenic leishmania secrete antigenically related chitinases which are encoded by a highly conserved gene locus. Exp Parasitol (2000) 0.90
Formation and composition of the peritrophic membrane in the sand fly, Phlebotomus perniciosus (Diptera: Psychodidae). J Med Entomol (1993) 0.87
Haemoglobin inhibits the development of infective promastigotes and chitinase secretion in Leishmania major cultures. Parasitology (1994) 0.84
Down-regulation of gp63 in Leishmania amazonensis reduces its early development in Lutzomyia longipalpis. Microbes Infect (2004) 0.81
Global topological features of cancer proteins in the human interactome. Bioinformatics (2006) 4.17
Reversal of DNA alkylation damage by two human dioxygenases. Proc Natl Acad Sci U S A (2002) 3.62
Transmission of cutaneous leishmaniasis by sand flies is enhanced by regurgitation of fPPG. Nature (2004) 2.36
Repair of alkylated DNA: recent advances. DNA Repair (Amst) (2006) 2.34
Protein-protein binding affinity prediction on a diverse set of structures. Bioinformatics (2011) 2.29
Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania. Genome Res (2011) 1.90
Generation of Leishmania donovani axenic amastigotes: their growth and biological characteristics. Int J Parasitol (2004) 1.84
Matrix geometry determines optimal cancer cell migration strategy and modulates response to interventions. Nat Cell Biol (2013) 1.84
Planar polarization of the atypical myosin Dachs orients cell divisions in Drosophila. Genes Dev (2011) 1.82
A structure-based benchmark for protein-protein binding affinity. Protein Sci (2011) 1.81
OPCML at 11q25 is epigenetically inactivated and has tumor-suppressor function in epithelial ovarian cancer. Nat Genet (2003) 1.77
Mathematical modeling identifies Smad nucleocytoplasmic shuttling as a dynamic signal-interpreting system. Proc Natl Acad Sci U S A (2008) 1.75
Leishmania manipulation of sand fly feeding behavior results in enhanced transmission. PLoS Pathog (2007) 1.72
Distinct transmission cycles of Leishmania tropica in 2 adjacent foci, Northern Israel. Emerg Infect Dis (2006) 1.61
Discovery of markers of exposure specific to bites of Lutzomyia longipalpis, the vector of Leishmania infantum chagasi in Latin America. PLoS Negl Trop Dis (2010) 1.60
Agent-based simulation of notch-mediated tip cell selection in angiogenic sprout initialisation. J Theor Biol (2007) 1.60
A lipophosphoglycan-independent development of Leishmania in permissive sand flies. Microbes Infect (2007) 1.58
Outbreak of cutaneous leishmaniasis in northern Israel. J Infect Dis (2003) 1.57
Cluster analysis of networks generated through homology: automatic identification of important protein communities involved in cancer metastasis. BMC Bioinformatics (2006) 1.57
Proteomic analysis of the secretome of Leishmania donovani. Genome Biol (2008) 1.54
Leishmania development in sand flies: parasite-vector interactions overview. Parasit Vectors (2012) 1.52
Increased transmission potential of Leishmania major/Leishmania infantum hybrids. Int J Parasitol (2007) 1.48
Sand flies and Leishmania: specific versus permissive vectors. Trends Parasitol (2007) 1.47
The relationship between the flexibility of proteins and their conformational states on forming protein-protein complexes with an application to protein-protein docking. J Mol Biol (2005) 1.41
Cutaneous leishmaniasis caused by Leishmania infantum transmitted by Phlebotomus tobbi. Int J Parasitol (2008) 1.40
Community-wide assessment of protein-interface modeling suggests improvements to design methodology. J Mol Biol (2011) 1.40
Tipping the balance: robustness of tip cell selection, migration and fusion in angiogenesis. PLoS Comput Biol (2009) 1.40
Leishmania in sand flies: comparison of quantitative polymerase chain reaction with other techniques to determine the intensity of infection. J Med Entomol (2008) 1.40
Two separate growth phases during the development of Leishmania in sand flies: implications for understanding the life cycle. Int J Parasitol (2003) 1.39
SwarmDock: a server for flexible protein-protein docking. Bioinformatics (2013) 1.32
Measurement of recent exposure to Phlebotomus argentipes, the vector of Indian visceral Leishmaniasis, by using human antibody responses to sand fly saliva. Am J Trop Med Hyg (2010) 1.30
Characterization of a defensin from the sand fly Phlebotomus duboscqi induced by challenge with bacteria or the protozoan parasite Leishmania major. Infect Immun (2004) 1.29
Kinetics of canine antibody response to saliva of the sand fly Lutzomyia longipalpis. Vector Borne Zoonotic Dis (2008) 1.27
Evidence incriminating midges (Diptera: Ceratopogonidae) as potential vectors of Leishmania in Australia. Int J Parasitol (2011) 1.25
High degree of conservancy among secreted salivary gland proteins from two geographically distant Phlebotomus duboscqi sandflies populations (Mali and Kenya). BMC Genomics (2006) 1.20
Community-wide evaluation of methods for predicting the effect of mutations on protein-protein interactions. Proteins (2013) 1.20
Different Smad2 partners bind a common hydrophobic pocket in Smad2 via a defined proline-rich motif. EMBO J (2002) 1.20
Synthetic glycovaccine protects against the bite of leishmania-infected sand flies. J Infect Dis (2006) 1.18
Sand fly saliva: effects on host immune response and Leishmania transmission. Folia Parasitol (Praha) (2006) 1.16
Recombinant HA1 produced in E. coli forms functional oligomers and generates strain-specific SRID potency antibodies for pandemic influenza vaccines. Vaccine (2011) 1.14
Experimental transmission of Leishmania tropica to hyraxes (Procavia capensis) by the bite of Phlebotomus arabicus. Microbes Infect (2006) 1.14
The stage-regulated HASPB and SHERP proteins are essential for differentiation of the protozoan parasite Leishmania major in its sand fly vector, Phlebotomus papatasi. Cell Microbiol (2010) 1.13
Analysis of salivary transcripts and antigens of the sand fly Phlebotomus arabicus. BMC Genomics (2009) 1.11
Sand fly specificity of saliva-mediated protective immunity in Leishmania amazonensis-BALB/c mouse model. Microbes Infect (2005) 1.11
Sergentomyia schwetzi is not a competent vector for Leishmania donovani and other Leishmania species pathogenic to humans. Parasit Vectors (2013) 1.11
Visualisation of Leishmania donovani fluorescent hybrids during early stage development in the sand fly vector. PLoS One (2011) 1.11
Canine antibody response to Phlebotomus perniciosus bites negatively correlates with the risk of Leishmania infantum transmission. PLoS Negl Trop Dis (2011) 1.10
Effect of temperature on metabolism of Phlebotomus papatasi (Diptera: Psychodidae). J Med Entomol (2007) 1.10
Implicit flexibility in protein docking: cross-docking and local refinement. Proteins (2007) 1.10
Serological markers of sand fly exposure to evaluate insecticidal nets against visceral leishmaniasis in India and Nepal: a cluster-randomized trial. PLoS Negl Trop Dis (2011) 1.08
In silico protein recombination: enhancing template and sequence alignment selection for comparative protein modelling. J Mol Biol (2003) 1.07
Experimental transmission of Leishmania infantum by two major vectors: a comparison between a viscerotropic and a dermotropic strain. PLoS Negl Trop Dis (2011) 1.07
Recognition of phosphorylated-Smad2-containing complexes by a novel Smad interaction motif. Mol Cell Biol (2004) 1.06
Peritrophic matrix of Phlebotomus duboscqi and its kinetics during Leishmania major development. Cell Tissue Res (2009) 1.05
A dyad of lymphoblastic lysosomal cysteine proteases degrades the antileukemic drug L-asparaginase. J Clin Invest (2009) 1.05
ITS 2 sequences heterogeneity in Phlebotomus sergenti and Phlebotomus similis (Diptera, Psychodidae): possible consequences in their ability to transmit Leishmania tropica. Int J Parasitol (2002) 1.05
Leishmania tropica in the black rat (Rattus rattus): persistence and transmission from asymptomatic host to sand fly vector Phlebotomus sergenti. Microbes Infect (2003) 1.05
Phlebotomus orientalis sand flies from two geographically distant Ethiopian localities: biology, genetic analyses and susceptibility to Leishmania donovani. PLoS Negl Trop Dis (2013) 1.04
Molecular homogeneity in diverse geographical populations of Phlebotomus papatasi (Diptera, Psychodidae) inferred from ND4 mtDNA and ITS2 rDNA Epidemiological consequences. Infect Genet Evol (2007) 1.04
Inhibition of trypsin expression in Lutzomyia longipalpis using RNAi enhances the survival of Leishmania. Parasit Vectors (2009) 1.03
Leishmania major glycosylation mutants require phosphoglycans (lpg2-) but not lipophosphoglycan (lpg1-) for survival in permissive sand fly vectors. PLoS Negl Trop Dis (2010) 1.02
Salivary gland transcriptomes and proteomes of Phlebotomus tobbi and Phlebotomus sergenti, vectors of leishmaniasis. PLoS Negl Trop Dis (2012) 1.02
Multilocus microsatellite typing (MLMT) of strains from Turkey and Cyprus reveals a novel monophyletic L. donovani sensu lato group. PLoS Negl Trop Dis (2012) 1.01
SwarmDock and the use of normal modes in protein-protein docking. Int J Mol Sci (2010) 1.01
A real-time PCR assay to estimate Leishmania chagasi load in its natural sand fly vector Lutzomyia longipalpis. Trans R Soc Trop Med Hyg (2008) 1.01
A Markov-chain model description of binding funnels to enhance the ranking of docked solutions. Proteins (2013) 1.01
Gene silencing in phlebotomine sand flies: Xanthine dehydrogenase knock down by dsRNA microinjections. Insect Biochem Mol Biol (2008) 1.00
Hyaluronidase of bloodsucking insects and its enhancing effect on leishmania infection in mice. PLoS Negl Trop Dis (2008) 0.99
Molecular characterization, expression, and in vivo analysis of LmexCht1: the chitinase of the human pathogen, Leishmania mexicana. J Biol Chem (2004) 0.99
Leishmania donovani and cutaneous leishmaniasis, Sri Lanka. Emerg Infect Dis (2007) 0.99
Stage-specific adhesion of Leishmania promastigotes to sand fly midguts assessed using an improved comparative binding assay. PLoS Negl Trop Dis (2010) 0.98
Modeling protein association mechanisms and kinetics. Curr Opin Struct Biol (2013) 0.96
Flexible relaxation of rigid-body docking solutions. Proteins (2007) 0.96
Colonisation resistance in the sand fly gut: Leishmania protects Lutzomyia longipalpis from bacterial infection. Parasit Vectors (2014) 0.96
Rational engineering of L-asparaginase reveals importance of dual activity for cancer cell toxicity. Blood (2010) 0.96
Can MM-PBSA calculations predict the specificities of protein kinase inhibitors? J Comput Chem (2006) 0.95
Evidence to support two conspecific cytological races on Anopheles aconitus in Thailand. J Vector Ecol (2005) 0.95
The scoring of poses in protein-protein docking: current capabilities and future directions. BMC Bioinformatics (2013) 0.95
Investigation of the bacterial communities associated with females of Lutzomyia sand fly species from South America. PLoS One (2012) 0.95
Blood meal identification and parasite detection in laboratory-fed and field-captured Lutzomyia longipalpis by PCR using FTA databasing paper. Acta Trop (2008) 0.95
The protective effect against Leishmania infection conferred by sand fly bites is limited to short-term exposure. Int J Parasitol (2011) 0.94
Novel use of a genetic algorithm for protein structure prediction: searching template and sequence alignment space. Proteins (2003) 0.94
Molecular and functional analyses of a novel class I secretory nuclease from the human pathogen, Leishmania donovani. J Biol Chem (2007) 0.93
Development of synchronous VHL syndrome tumors reveals contingencies and constraints to tumor evolution. Genome Biol (2014) 0.92
Alternating evolutionary pressure in a genetic algorithm facilitates protein model selection. BMC Struct Biol (2008) 0.92
Kinetics of antibody response in BALB/c and C57BL/6 mice bitten by Phlebotomus papatasi. PLoS Negl Trop Dis (2012) 0.92
Detection and refinement of encounter complexes for protein-protein docking: taking account of macromolecular crowding. Proteins (2010) 0.92
A link between sequence conservation and domain motion within the AAA+ family. J Struct Biol (2004) 0.91
Caspar-like gene depletion reduces Leishmania infection in sand fly host Lutzomyia longipalpis. J Biol Chem (2012) 0.91
Developmentally regulated expression of a cell surface class I nuclease in Leishmania mexicana. Int J Parasitol (2002) 0.91
The life cycle and host specificity of Psychodiella sergenti n. sp. and Ps. tobbi n. sp. (Protozoa: Apicomplexa) in sand flies Phlebotomus sergenti and Ph. tobbi (Diptera: Psychodidae). J Invertebr Pathol (2010) 0.90
Blind prediction of interfacial water positions in CAPRI. Proteins (2013) 0.90
Functional recycling of C2 domains throughout evolution: a comparative study of synaptotagmin, protein kinase C and phospholipase C by sequence, structural and modelling approaches. J Mol Biol (2003) 0.90
Molecular dissection and expression of the LdK39 kinesin in the human pathogen, Leishmania donovani. Mol Microbiol (2007) 0.89
Kinetic rate constant prediction supports the conformational selection mechanism of protein binding. PLoS Comput Biol (2012) 0.89