Published in Dtsch Med Wochenschr on February 01, 2008
[Patients with mild cognition impairment should not be treated with antidementia agents, except in studies]. Dtsch Med Wochenschr (2008) 0.75
Genetic and physical maps of Saccharomyces cerevisiae. Nature (1997) 21.48
Current concepts in mild cognitive impairment. Arch Neurol (2001) 18.09
A new generation of the IMAGIC image processing system. J Struct Biol (1996) 12.57
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet (2013) 9.46
RPS2 of Arabidopsis thaliana: a leucine-rich repeat class of plant disease resistance genes. Science (1994) 8.99
Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection. Nat Med (2000) 7.48
Pathologic correlates of incidental MRI white matter signal hyperintensities. Neurology (1993) 5.72
Supplemental perioperative oxygen to reduce the incidence of surgical-wound infection. N Engl J Med (2000) 5.22
Single-particle electron cryo-microscopy: towards atomic resolution. Q Rev Biophys (2000) 4.86
FCA, a gene controlling flowering time in Arabidopsis, encodes a protein containing RNA-binding domains. Cell (1997) 4.79
The Arabidopsis downy mildew resistance gene RPP5 shares similarity to the toll and interleukin-1 receptors with N and L6. Plant Cell (1997) 4.53
Discrimination between Alzheimer dementia and controls by automated analysis of multicenter FDG PET. Neuroimage (2002) 3.88
Histopathologic analysis of foci of signal loss on gradient-echo T2*-weighted MR images in patients with spontaneous intracerebral hemorrhage: evidence of microangiopathy-related microbleeds. AJNR Am J Neuroradiol (1999) 3.67
Specific C-receptors for itch in human skin. J Neurosci (1997) 3.51
Role of chromosome territories in the functional compartmentalization of the cell nucleus. Cold Spring Harb Symp Quant Biol (1993) 3.38
Cerebrospinal fluid tau and beta-amyloid 42 proteins identify Alzheimer disease in subjects with mild cognitive impairment. Arch Neurol (2002) 3.17
Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay. J Biol Chem (1996) 3.10
A novel zinc finger protein is encoded by the Arabidopsis LSD1 gene and functions as a negative regulator of plant cell death. Cell (1997) 2.91
Selective postoperative inhibition of gastrointestinal opioid receptors. N Engl J Med (2001) 2.89
Incident lacunes influence cognitive decline: the LADIS study. Neurology (2011) 2.81
Mild hypothermia increases blood loss and transfusion requirements during total hip arthroplasty. Lancet (1996) 2.70
Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways. Blood (2000) 2.70
Construction of an intron-containing marker gene: splicing of the intron in transgenic plants and its use in monitoring early events in Agrobacterium-mediated plant transformation. Mol Gen Genet (1990) 2.69
Effect of dexamethasone on the duration of interscalene nerve blocks with ropivacaine or bupivacaine. Br J Anaesth (2011) 2.63
Tumor initiators and promoters in the induction of Epstein-Barr virus. Proc Natl Acad Sci U S A (1979) 2.55
Forespore-specific transcription of a gene in the signal transduction pathway that governs Pro-sigma K processing in Bacillus subtilis. Genes Dev (1991) 2.53
Improvement of hepatorenal syndrome with extracorporeal albumin dialysis MARS: results of a prospective, randomized, controlled clinical trial. Liver Transpl (2000) 2.52
CSF soluble amyloid precursor proteins in the diagnosis of incipient Alzheimer disease. Neurology (2011) 2.41
Chemical response pattern of different classes of C-nociceptors to pruritogens and algogens. J Neurophysiol (2003) 2.39
Head injury and the risk of AD in the MIRAGE study. Neurology (2000) 2.34
Postnatal passive immunization of neonatal macaques with a triple combination of human monoclonal antibodies against oral simian-human immunodeficiency virus challenge. J Virol (2001) 2.30
Risk factors for progression of brain atrophy in aging: six-year follow-up of normal subjects. Neurology (2005) 2.24
A comparative linkage map of oilseed rape and its use for QTL analysis of seed oil and erucic acid content. Theor Appl Genet (2006) 2.21
Identification and map position of YAC clones comprising one-third of the Arabidopsis genome. Plant J (1991) 2.17
Expression of the RET/PTC fusion gene as a marker for papillary carcinoma in Hashimoto's thyroiditis. Laryngoscope (1997) 2.15
Heat flow and distribution during induction of general anesthesia. Anesthesiology (1995) 2.12
Intravenous immunoglobulins containing antibodies against beta-amyloid for the treatment of Alzheimer's disease. J Neurol Neurosurg Psychiatry (2004) 2.12
Tau and Abeta42 protein in CSF of patients with frontotemporal degeneration. Neurology (2002) 2.12
Determinants of brain iron in multiple sclerosis: a quantitative 3T MRI study. Neurology (2011) 2.11
Net costs of dementia by disease stage. Acta Psychiatr Scand (2011) 2.11
ClpS is an essential component of the N-end rule pathway in Escherichia coli. Nature (2006) 2.09
Criteria for an increased specificity of MRI interpretation in elderly subjects with suspected multiple sclerosis. Neurology (1988) 2.03
Effect of APOE genotype on amyloid plaque load and gray matter volume in Alzheimer disease. Neurology (2009) 1.99
Human adeno-associated virus type 5 is only distantly related to other known primate helper-dependent parvoviruses. J Virol (1999) 1.94
Examination of the current top candidate genes for AD in a genome-wide association study. Mol Psychiatry (2009) 1.89
Efficient transformation of Arabidopsis thaliana using direct gene transfer to protoplasts. Mol Gen Genet (1989) 1.86
Identification of mutants in metabolically regulated gene expression. Plant J (1997) 1.86
Risk of dementia among relatives of Alzheimer's disease patients in the MIRAGE study: What is in store for the oldest old? Neurology (1996) 1.85
White matter signal abnormalities in normal individuals: correlation with carotid ultrasonography, cerebral blood flow measurements, and cerebrovascular risk factors. Stroke (1988) 1.85
Mild intraoperative hypothermia prolongs postanesthetic recovery. Anesthesiology (1997) 1.84
Multidrug resistance in Candida albicans: disruption of the BENr gene. Antimicrob Agents Chemother (1995) 1.84
CT and MRI rating of white matter lesions. Cerebrovasc Dis (2002) 1.83
Neuropsychological studies of asymptomatic human immunodeficiency virus-type-1 infected individuals. The HNRC Group. HIV Neurobehavioral Research Center. J Int Neuropsychol Soc (1995) 1.81
Comparative sequence analysis reveals extensive microcolinearity in the lateral suppressor regions of the tomato, Arabidopsis, and Capsella genomes. Plant Cell (2001) 1.79
Plasma creatinine determination in mice and rats: an enzymatic method compares favorably with a high-performance liquid chromatography assay. Kidney Int (2006) 1.79
Surfactant alterations in severe pneumonia, acute respiratory distress syndrome, and cardiogenic lung edema. Am J Respir Crit Care Med (1996) 1.79
Biomarker validation of a cued recall memory deficit in prodromal Alzheimer disease. Neurology (2012) 1.78
Visual rating of age-related white matter changes on magnetic resonance imaging: scale comparison, interrater agreement, and correlations with quantitative measurements. Stroke (2003) 1.78
Ondansetron is no more effective than supplemental intraoperative oxygen for prevention of postoperative nausea and vomiting. Anesth Analg (2001) 1.78
Association of an interleukin 1 alpha polymorphism with Alzheimer's disease. Neurology (2000) 1.76
Risk factors for incident mild cognitive impairment--results from the German Study on Ageing, Cognition and Dementia in Primary Care Patients (AgeCoDe). Acta Psychiatr Scand (2009) 1.76
Comparative genome analysis reveals extensive conservation of genome organisation for Arabidopsis thaliana and Capsella rubella. Plant J (2000) 1.74
Evidence for a nuclear compartment of transcription and splicing located at chromosome domain boundaries. Chromosome Res (1993) 1.72
Regional variability in the prevalence of cerebral white matter lesions: an MRI study in 9 European countries (CASCADE). Neuroepidemiology (2005) 1.70
Chilling sensitivity of Arabidopsis thaliana with genetically engineered membrane lipids. EMBO J (1992) 1.69
Transverse-momentum and pseudorapidity distributions of charged hadrons in pp collisions at square root of s = 7 TeV. Phys Rev Lett (2010) 1.67
Hippocampal atrophy in Alzheimer disease: age matters. Neurology (2006) 1.66
Corpus callosum atrophy as a predictor of age-related cognitive and motor impairment: a 3-year follow-up of the LADIS study cohort. J Neurol Sci (2011) 1.66
Familial de Lange syndrome with chromosome abnormalities. Pediatrics (1966) 1.64
Psychosocial work factors and dementia. Occup Environ Med (2004) 1.62
High prevalence of pathogenic mutations in patients with early-onset dementia detected by sequence analyses of four different genes. Am J Hum Genet (2000) 1.61
Functional attributes discriminating mechano-insensitive and mechano-responsive C nociceptors in human skin. J Neurosci (1999) 1.61
A genetic variation of cathepsin D is a major risk factor for Alzheimer's disease. Ann Neurol (2000) 1.61
Intracellular responses to light from cat pigment epithelium: origin of the electroretinogram c-wave. Nature (1970) 1.61
Obstructive uropathy in the mouse: role of osteopontin in interstitial fibrosis and apoptosis. Kidney Int (1999) 1.60
Which nerve fibers mediate the axon reflex flare in human skin? Neuroreport (2000) 1.60
Phospho-tau/total tau ratio in cerebrospinal fluid discriminates Creutzfeldt-Jakob disease from other dementias. Mol Psychiatry (2003) 1.58
Study of the mass and spin-parity of the Higgs boson candidate via its decays to Z boson pairs. Phys Rev Lett (2013) 1.56
[Consensus recommendations for the assessment of fitness to drive in cognitively impaired patients]. Praxis (Bern 1994) (2012) 1.55
Soluble amyloid precursor proteins in the cerebrospinal fluid as novel potential biomarkers of Alzheimer's disease: a multicenter study. Mol Psychiatry (2008) 1.54
Subacute dementia and imaging correlates in a case of Fahr's disease. J Neurol Neurosurg Psychiatry (2004) 1.53
Arabidopsis phosphoribosylanthranilate isomerase: molecular genetic analysis of triplicate tryptophan pathway genes. Plant Cell (1995) 1.52
TOM1, an Arabidopsis gene required for efficient multiplication of a tobamovirus, encodes a putative transmembrane protein. Proc Natl Acad Sci U S A (2000) 1.52
MRI evidence of past cerebral microbleeds in a healthy elderly population. Neurology (1999) 1.50
Cerebral metabolic patterns at early stages of frontotemporal dementia and semantic dementia. A PET study. Neurobiol Aging (2004) 1.48
Keloid excision and recurrence prophylaxis via intradermal interferon-gamma injections: a pilot study. Laryngoscope (1996) 1.47
A randomized, double-blind, dose-response comparison of epidural fentanyl versus sufentanil analgesia after cesarean section. Anesth Analg (1997) 1.47
Astroglial and fibroblast growth factors have neurotrophic functions for cultured peripheral and central nervous system neurons. Proc Natl Acad Sci U S A (1987) 1.47
New derivatives of rifamycin antibiotics. Antimicrob Agents Chemother (Bethesda) (1966) 1.46
Antidepressants in 'depressed' schizophrenic inpatients. A controlled trial. Arch Gen Psychiatry (1989) 1.46
IDEAL: a 6-month, double-blind, placebo-controlled study of the first skin patch for Alzheimer disease. Neurology (2007) 1.45
The effect of auricular acupuncture on anaesthesia with desflurane. Anaesthesia (2002) 1.44
Multicenter assessment of CSF-phosphorylated tau for the prediction of conversion of MCI. Neurology (2007) 1.43
Progression to dementia in clinical subtypes of mild cognitive impairment. Dement Geriatr Cogn Disord (2006) 1.42
Episodic memory changes are associated with the APOE-epsilon 4 allele in nondemented older adults. Neurology (1995) 1.42
[On phenylketonuria. Carrying out of phenylalanine-low diet]. Dtsch Med Wochenschr (1967) 1.42