Loss of cholinergic neurons in the pedunculopontine nucleus in Parkinson's disease is related to disability of the patients.

PubWeight™: 1.10‹?› | Rank: Top 10%

🔗 View Article (PMID 18329941)

Published in Parkinsonism Relat Disord on March 10, 2008

Authors

Juha O Rinne1, Shuang Yong Ma, Myung Sik Lee, Yrjö Collan, Matias Röyttä

Author Affiliations

1: Department of Neurology, University of Turku and Turku University Hospital, FIN-20520 Turku, Finland.Turku, Finland. juha.rinne@tyks.fi

Articles citing this

Missing pieces in the Parkinson's disease puzzle. Nat Med (2010) 2.90

Effects of a central cholinesterase inhibitor on reducing falls in Parkinson disease. Neurology (2010) 2.14

Cholinergic mesencephalic neurons are involved in gait and postural disorders in Parkinson disease. J Clin Invest (2010) 1.64

The neurobiological basis of cognitive impairment in Parkinson's disease. Mov Disord (2014) 1.17

Thalamic cholinergic innervation and postural sensory integration function in Parkinson's disease. Brain (2013) 1.12

Alpha oscillations in the pedunculopontine nucleus correlate with gait performance in parkinsonism. Brain (2012) 1.02

Deep Brain Stimulation for Movement Disorders of Basal Ganglia Origin: Restoring Function or Functionality? Neurotherapeutics (2016) 0.96

Vestibular responses in the macaque pedunculopontine nucleus and central mesencephalic reticular formation. Neuroscience (2012) 0.89

Mapping track density changes in nigrostriatal and extranigral pathways in Parkinson's disease. Neuroimage (2014) 0.88

Our first decade of experience in deep brain stimulation of the brainstem: elucidating the mechanism of action of stimulation of the ventrolateral pontine tegmentum. J Neural Transm (Vienna) (2016) 0.86

The serendipity case of the pedunculopontine nucleus low-frequency brain stimulation: chasing a gait response, finding sleep, and cognition improvement. Front Neurol (2013) 0.86

Cell type specific sequestration of choline acetyltransferase and tyrosine hydroxylase within Lewy bodies. Acta Neuropathol (2010) 0.83

Functional Neuroanatomy for Posture and Gait Control. J Mov Disord (2017) 0.82

Deep brain stimulation of different pedunculopontine targets in a novel rodent model of parkinsonism. J Neurosci (2015) 0.81

Brainstem control of locomotion and muscle tone with special reference to the role of the mesopontine tegmentum and medullary reticulospinal systems. J Neural Transm (Vienna) (2015) 0.81

The ReSPonD trial--rivastigmine to stabilise gait in Parkinson's disease a phase II, randomised, double blind, placebo controlled trial to evaluate the effect of rivastigmine on gait in patients with Parkinson's disease who have fallen. BMC Neurol (2013) 0.80

The primate pedunculopontine nucleus region: towards a dual role in locomotion and waking state. J Neural Transm (Vienna) (2016) 0.78

The pedunculopontine tegmental nucleus: implications for a role in modulating spinal cord motoneuron excitability. J Neural Transm (Vienna) (2010) 0.78

Effect of augmenting cholinergic function on gait and balance. BMC Neurol (2015) 0.78

Involvement of cholinergic system in hyperactivity in dopamine-deficient mice. Neuropsychopharmacology (2015) 0.77

Models of α-synuclein aggregation in Parkinson's disease. Acta Neuropathol Commun (2014) 0.77

Mitochondrial abnormality associates with type-specific neuronal loss and cell morphology changes in the pedunculopontine nucleus in Parkinson disease. Am J Pathol (2013) 0.77

Pedunculopontine stimulation from primate to patient. J Neural Transm (Vienna) (2011) 0.77

The relationship between hippocampal volume and static postural sway: results from the GAIT study. Age (Dordr) (2016) 0.75

Maintaining balance against force perturbations: impaired mechanisms unresponsive to levodopa in Parkinson's disease. J Neurophysiol (2016) 0.75

The Serotonin Receptor 6 Antagonist Idalopirdine and Acetylcholinesterase Inhibitor Donepezil Have Synergistic Effects on Brain Activity-A Functional MRI Study in the Awake Rat. Front Pharmacol (2017) 0.75

Deep Brain Stimulation in Parkinson's Disease: New and Emerging Targets for Refractory Motor and Nonmotor Symptoms. Parkinsons Dis (2017) 0.75

Dopamine and the Brainstem Locomotor Networks: From Lamprey to Human. Front Neurosci (2017) 0.75

Articles by these authors

(truncated to the top 100)

The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes. Acta Neuropathol (2010) 2.42

Herpesviruses in brains in Alzheimer's and Parkinson's diseases. Ann Neurol (2003) 1.70

Acute liver failure after valproate exposure in patients with POLG1 mutations and the prognosis after liver transplantation. Liver Transpl (2014) 1.48

Immunohistochemical staining of estrogen and progesterone receptors: aspects for evaluating positivity and defining the cutpoints. Anticancer Res (2005) 1.25

Movement disorders associated with moyamoya disease: a report of 4 new cases and a review of literatures. Mov Disord (2010) 1.11

VEGF-1 expression in colorectal cancer is associated with disease localization, stage, and long-term disease-specific survival. Anticancer Res (2009) 1.06

Topographical distribution of cerebral cortical thinning in patients with mild Parkinson's disease without dementia. Mov Disord (2010) 1.05

Analysis of PARK genes in a Korean cohort of early-onset Parkinson disease. Neurogenetics (2008) 1.05

Diagnosis delay in Libyan female breast cancer. BMC Res Notes (2012) 1.05

MMP-9 (gelatinase B) expression is associated with disease-free survival and disease-specific survival in colorectal cancer patients. Cancer Invest (2010) 1.04

Analysis of cyclins A, B1, D1 and E in breast cancer in relation to tumour grade and other prognostic factors. BMC Res Notes (2009) 1.03

Homozygous W748S mutation in the POLG1 gene in patients with juvenile-onset Alpers syndrome and status epilepticus. Epilepsia (2008) 1.03

Correlation of nuclear morphometry of breast cancer in histological sections with clinicopathological features and prognosis. Anticancer Res (2009) 1.01

Psychogenic paroxysmal dyskinesia: the role of placebo in the diagnosis and management. Mov Disord (2009) 0.96

Neuropathic symptoms and findings in women with Fabry disease. Clin Neurophysiol (2008) 0.94

Association of mutations in the glucocerebrosidase gene with Parkinson disease in a Korean population. Neurosci Lett (2012) 0.94

A herpes simplex virus-derived replicative vector expressing LIF limits experimental demyelinating disease and modulates autoimmunity. PLoS One (2013) 0.94

Scoliosis in patients with Parkinson's disease. J Clin Neurol (2009) 0.94

Reconstruction of critical size calvarial bone defects in rabbits with glass-fiber-reinforced composite with bioactive glass granule coating. J Biomed Mater Res B Appl Biomater (2008) 0.93

Transgenic mice overexpressing neuropeptide Y in noradrenergic neurons: a novel model of increased adiposity and impaired glucose tolerance. Diabetes (2008) 0.93

Breast cancer patients in Libya: Comparison with European and central African patients. Oncol Lett (2011) 0.93

Nuclear morphometry in FNABs of breast disease in Libyans. Anticancer Res (2009) 0.92

Contralateral non-operated nerve to transected rat sciatic nerve shows increased expression of IL-1beta, TGF-beta1, TNF-alpha, and IL-10. J Neuroimmunol (2002) 0.91

Stereological study of the neuronal number and volume of 38 brain subdivisions of subjects diagnosed with autism reveals significant alterations restricted to the striatum, amygdala and cerebellum. Acta Neuropathol Commun (2014) 0.90

Primary progressive freezing gait in a patient with CO-induced parkinsonism. Mov Disord (2010) 0.89

Abnormal intracellular accumulation and extracellular Aβ deposition in idiopathic and Dup15q11.2-q13 autism spectrum disorders. PLoS One (2012) 0.89

Immunohistochemically detectable bcl-2 expression in metastatic melanoma: association with survival and treatment response. Oncology (2002) 0.88

Differences between the pattern of developmental abnormalities in autism associated with duplications 15q11.2-q13 and idiopathic autism. J Neuropathol Exp Neurol (2012) 0.88

Prognostic value of proliferation markers: immunohistochemical ki-67 expression and cytometric s-phase fraction of women with breast cancer in libya. J Cancer (2012) 0.87

Neuronal nucleus and cytoplasm volume deficit in children with autism and volume increase in adolescents and adults. Acta Neuropathol Commun (2015) 0.87

Loss of E-cadherin expression predicts disease recurrence and shorter survival in colorectal carcinoma. APMIS (2012) 0.87

High cyclooxygenase-2 expression is associated with advanced stages in colorectal cancer. Anticancer Res (2013) 0.87

Cytokine responses during chronic denervation. J Neuroinflammation (2005) 0.86

Prognostic significance of matrix metalloproteinase-9 (MMP-9) in stage II colorectal carcinoma. J Gastrointest Cancer (2009) 0.86

Cerebral glucose metabolism of Parkinson's disease patients with mild cognitive impairment. Eur Neurol (2010) 0.86

Contribution of olivofloccular circuitry developmental defects to atypical gaze in autism. Brain Res (2013) 0.85

Apoptosis in breast cancer: Nigerian vs. Finnish material. Anal Quant Cytol Histol (2002) 0.84

Herpes simplex virus type 1 infection induces upregulation of interleukin-23 (p19) mRNA expression in trigeminal ganglia of BALB/c mice. J Interferon Cytokine Res (2002) 0.84

Interaction between matrix metalloproteinase 3 and the epsilon4 allele of apolipoprotein E increases the risk of Alzheimer's disease in Finns. Neurosci Lett (2004) 0.84

[(11)C]PIB-, [(18)F]FDG-PET and MRI imaging in patients with Parkinson's disease with and without dementia. Parkinsonism Relat Disord (2010) 0.84

Bilateral ballism after herpes encephalitis with thalamic lesion. Parkinsonism Relat Disord (2009) 0.84

Nuclear morphometry in prognostication of breast cancer in Saudi Arabian patients: comparison with European and African breast cancer. Anticancer Res (2010) 0.84

Loss of MUC2 expression predicts disease recurrence and poor outcome in colorectal carcinoma. Tumour Biol (2012) 0.84

Rhabdomyolysis induced by severe levodopa induced dyskinesia in a patient with Parkinson's disease. J Neurol (2011) 0.83

Sonographic abnormalities in idiopathic restless legs syndrome (RLS) and RLS in Parkinson's disease. Parkinsonism Relat Disord (2010) 0.83

Different cerebral cortical areas influence the effect of subthalamic nucleus stimulation on parkinsonian motor deficits and freezing of gait. Mov Disord (2007) 0.83

A rare mitochondrial DNA haplotype observed in Koreans. Hum Biol (2002) 0.83

Hox genes from the earthworm Perionyx excavatus. Dev Genes Evol (2003) 0.83

Altered expression of Autism-associated genes in the brain of Fragile X mouse model. Biochem Biophys Res Commun (2009) 0.82

Brain-region-specific alterations of the trajectories of neuronal volume growth throughout the lifespan in autism. Acta Neuropathol Commun (2014) 0.82

Downregulation of the LAR protein tyrosine phosphatase receptor is associated with increased dentate gyrus neurogenesis and an increased number of granule cell layer neurons. Mol Cell Neurosci (2006) 0.82

Prognostic value of necrosis in Nigerian breast cancer. Adv Clin Path (2002) 0.82

Prognostic value of various staging and grading systems in proximal colon cancer. Eur J Surg (2002) 0.81

Image DNA cytometry in FNABs of Libyan breast disease. Anticancer Res (2010) 0.81

Cerebral cortical areas in which thickness correlates with severity of motor deficits of Parkinson's disease. J Neurol (2011) 0.80

Estrogen receptor, progesterone receptor, and nuclear size features in female breast cancer in Libya: correlation with clinical features and survival. Anticancer Res (2012) 0.80

Anticholinergic-responsive gait freezing in a patient with pantothenate kinase-associated neurodegeneration. Mov Disord (2008) 0.80

Abnormal temporal discrimination threshold in patients with multiple system atrophy. Mov Disord (2007) 0.80

Up-regulation of alpha-catenin is associated with increased lymph node involvement in colorectal cancer. World J Gastroenterol (2008) 0.79

In Vivo and In Vitro Study of a Polylactide-Fiber-Reinforced β-Tricalcium Phosphate Composite Cage in an Ovine Anterior Cervical Intercorporal Fusion Model. Int J Biomater (2011) 0.79

Group IIA phospholipase A(2) concentration of tears in patients with ocular rosacea. Acta Ophthalmol Scand (2005) 0.79

Bactericidal/permeability-increasing protein in lacrimal gland and in tears of healthy subjects. Graefes Arch Clin Exp Ophthalmol (2005) 0.79

Imaging evidence of nigral damage in dystonia secondary to disulfiram intoxication. Mov Disord (2011) 0.78

Brain glucose metabolism in neuropathologically confirmed multiple system atrophy. J Neurol (2013) 0.78

Normal dopamine transporter SPECT in neuropathologically confirmed corticobasal degeneration. J Neurol (2013) 0.78

Absence of association between an intercellular adhesion molecule 1 gene E469K polymorphism and Alzheimer's disease in Finnish patients. Neurosci Lett (2003) 0.78

Sympathetic nervous system-targeted neuropeptide Y overexpression in mice enhances neointimal formation in response to vascular injury. Peptides (2008) 0.78

Spread and replication of and immune response to gamma134.5-negative herpes simplex virus type 1 vectors in BALB/c mice. J Virol (2004) 0.78

Enhanced LH action in transgenic female mice expressing hCGbeta-subunit induces pituitary prolactinomas; the role of high progesterone levels. Endocr Relat Cancer (2010) 0.78

Nuclear size as prognostic determinant in stage II and stage III colorectal adenocarcinoma. Anticancer Res (2006) 0.78

Proliferative activity in Libyan breast cancer with comparison to European and Central African patients. Biomed Res Int (2013) 0.78

Factors related to outcomes of subthalamic deep brain stimulation in Parkinson's disease. J Korean Neurosurg Soc (2013) 0.77

Group IIA phospholipase A2 content of tears in patients with atopic blepharoconjunctivitis. Graefes Arch Clin Exp Ophthalmol (2004) 0.77

Prognostic significance of DNA image cytometry in Libyan breast cancer. Oncology (2012) 0.77

Prognostic value of mitotic counts in breast cancer of Saudi Arabian patients. Anticancer Res (2011) 0.77

The endoneurial response to microsurgically removed epi- and perineurium. J Peripher Nerv Syst (2002) 0.77

Mesencephalic midline change on transcranial sonography in early Parkinson's disease patients with depression. J Neurol Sci (2011) 0.77

Apoptotic activity in Libyan breast cancer. World J Surg Oncol (2012) 0.77

Microsatellite genotyping of chromosome 14q13.2-14q13 in the vicinity of proteasomal gene PSMA6 and association with Graves' disease in the Latvian population. Immunogenetics (2004) 0.77

Frequencies of single nucleotide polymorphism in alcohol dehydrogenase7 gene in patients with multiple system atrophy and controls. Mov Disord (2003) 0.77

Genomic changes of the 55 kDa subunit of DNA polymerase epsilon in human breast cancer. Cancer Genomics Proteomics (2009) 0.76

Progressive external ophthalmoplegia in southwestern Finland: a clinical and genetic study. Neuroepidemiology (2012) 0.76

Prognostic value of bcl-2 expression among women with breast cancer in Libya. Tumour Biol (2013) 0.76

Brain ¹⁸F-FDG and ¹¹C-PiB PET findings in two siblings with FTD/ALS associated with the C9ORF72 repeat expansion. Neurocase (2012) 0.76

Mutations/polymorphisms in the 55 kDa subunit of DNA polymerase epsilon in human colorectal cancer. Cancer Genomics Proteomics (2010) 0.76

Gene expression profile in the anterior regeneration of the earthworm using expressed sequence tags. Biosci Biotechnol Biochem (2009) 0.76

A patient with genetically confirmed myoclonus-dystonia responded to anticholinergic treatment and improved spontaneously. J Clin Neurol (2011) 0.75

Moyamoya disease presenting with paroxysmal exercise-induced dyskinesia. Parkinsonism Relat Disord (2006) 0.75

Genomic analysis of the 55 kDa subunit of DNA polymerase epsilon in human intracranial neoplasms. Cancer Genomics Proteomics (2010) 0.75

Effect of freezing on histologic grading of invasive ductal breast cancer. Anal Quant Cytol Histol (2003) 0.75

Nuclear area is a prognostic determinant in advanced colorectal cancer. Anticancer Res (2005) 0.75

The effect of combined neurolytic blocking agent 5% phenol-glycerol in rat sciatic nerve. Acta Neuropathol (2003) 0.75

Levodopa responsive hemidystonia associated with contralateral nigral lesion. J Neurol (2010) 0.75

Flexor tendon healing within the tendon sheath using bioabsorbable poly-L/D-lactide 96/4 suture. A histological in vivo study with rabbits. J Mater Sci Mater Med (2014) 0.75

The perineurium modifies the effects of phenol and glycerol in rat sciatic nerve. Acta Neuropathol (2004) 0.75

The influence of training level and surgical experience on survival in colorectal cancer. Langenbecks Arch Surg (2004) 0.75

Giant somatosensory evoked potential in a patient with shaking TIA. Mov Disord (2009) 0.75

Identification of an intronic TG repeat polymorphism in the human proteasome core particle PROS-27K gene. DNA Seq (2002) 0.75

Functional peak dose dyskinesia in patients with Parkinson's disease. Parkinsonism Relat Disord (2008) 0.75

A PCR-based analysis of Hox genes in an earthworm, Eisenia andrei (Annelida: Oligochaeta). Biochem Genet (2004) 0.75