| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
A near-infrared fluorophore for live-cell super-resolution microscopy of cellular proteins.
|
Nat Chem
|
2013
|
2.61
|
|
2
|
Selective fluorescence labeling of lipids in living cells.
|
Angew Chem Int Ed Engl
|
2009
|
1.89
|
|
3
|
Amino acids for Diels-Alder reactions in living cells.
|
Angew Chem Int Ed Engl
|
2012
|
1.83
|
|
4
|
Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate.
|
Nature
|
2013
|
1.59
|
|
5
|
Simultaneous recording of multiple cellular events by FRET.
|
ACS Chem Biol
|
2008
|
1.57
|
|
6
|
Membrane-permeant phosphoinositide derivatives as modulators of growth factor signaling and neurite outgrowth.
|
Chem Biol
|
2009
|
1.53
|
|
7
|
Switching heterotrimeric G protein subunits with a chemical dimerizer.
|
Chem Biol
|
2011
|
1.53
|
|
8
|
How do patients with rare diseases experience the medical encounter? Exploring role behavior and its impact on patient-physician interaction.
|
Health Policy
|
2012
|
1.39
|
|
9
|
Live-cell imaging of enzyme-substrate interaction reveals spatial regulation of PTP1B.
|
Science
|
2007
|
1.36
|
|
10
|
Genetically encoded copper-free click chemistry.
|
Angew Chem Int Ed Engl
|
2011
|
1.35
|
|
11
|
Principles for designing fluorescent sensors and reporters.
|
Nat Chem Biol
|
2011
|
1.33
|
|
12
|
Genetic encoding of a bicyclo[6.1.0]nonyne-charged amino acid enables fast cellular protein imaging by metal-free ligation.
|
Chembiochem
|
2012
|
1.25
|
|
13
|
The ENaC-overexpressing mouse as a model of cystic fibrosis lung disease.
|
J Cyst Fibros
|
2011
|
1.20
|
|
14
|
Minimal tags for rapid dual-color live-cell labeling and super-resolution microscopy.
|
Angew Chem Int Ed Engl
|
2014
|
1.20
|
|
15
|
Does cellular hydrogen peroxide diffuse or act locally?
|
Antioxid Redox Signal
|
2010
|
1.19
|
|
16
|
Protein translocation as a tool: The current rapamycin story.
|
FEBS Lett
|
2012
|
1.16
|
|
17
|
HyPer-3: a genetically encoded H(2)O(2) probe with improved performance for ratiometric and fluorescence lifetime imaging.
|
ACS Chem Biol
|
2013
|
1.13
|
|
18
|
Calcium-dependent regulation of NF-(kappa)B activation in cystic fibrosis airway epithelial cells.
|
Cell Signal
|
2005
|
1.09
|
|
19
|
Membrane-bound FRET probe visualizes MMP12 activity in pulmonary inflammation.
|
Nat Chem Biol
|
2009
|
1.07
|
|
20
|
Airway surface liquid volume regulation determines different airway phenotypes in liddle compared with betaENaC-overexpressing mice.
|
J Biol Chem
|
2010
|
1.05
|
|
21
|
Rapid development of genetically encoded FRET reporters.
|
ACS Chem Biol
|
2011
|
1.05
|
|
22
|
In vivo profiling and visualization of cellular protein-lipid interactions using bifunctional fatty acids.
|
Angew Chem Int Ed Engl
|
2013
|
1.01
|
|
23
|
Lack of neutrophil elastase reduces inflammation, mucus hypersecretion, and emphysema, but not mucus obstruction, in mice with cystic fibrosis-like lung disease.
|
Am J Respir Crit Care Med
|
2014
|
1.01
|
|
24
|
Annexin A4 self-association modulates general membrane protein mobility in living cells.
|
Mol Biol Cell
|
2006
|
0.99
|
|
25
|
A dual parameter FRET probe for measuring PKC and PKA activity in living cells.
|
J Am Chem Soc
|
2006
|
0.96
|
|
26
|
A small-molecule FRET probe to monitor phospholipase A2 activity in cells and organisms.
|
Angew Chem Int Ed Engl
|
2006
|
0.92
|
|
27
|
Activation of membrane-permeant caged PtdIns(3)P induces endosomal fusion in cells.
|
Nat Chem Biol
|
2010
|
0.92
|
|
28
|
PLCβ isoforms differ in their subcellular location and their CT-domain dependent interaction with Gαq.
|
Cell Signal
|
2012
|
0.91
|
|
29
|
Genetically encoded FRET probe for PKC activity based on pleckstrin.
|
J Am Chem Soc
|
2004
|
0.91
|
|
30
|
Airway mucus obstruction triggers macrophage activation and matrix metalloproteinase 12-dependent emphysema.
|
Am J Respir Cell Mol Biol
|
2014
|
0.91
|
|
31
|
Spatially resolved monitoring of neutrophil elastase activity with ratiometric fluorescent reporters.
|
Angew Chem Int Ed Engl
|
2012
|
0.89
|
|
32
|
Plasma membrane phosphoinositide balance regulates cell shape during Drosophila embryo morphogenesis.
|
J Cell Biol
|
2014
|
0.89
|
|
33
|
Photoactivatable and cell-membrane-permeable phosphatidylinositol 3,4,5-trisphosphate.
|
Angew Chem Int Ed Engl
|
2011
|
0.88
|
|
34
|
The power of fluorogenic probes.
|
Angew Chem Int Ed Engl
|
2013
|
0.88
|
|
35
|
mCLCA3 does not contribute to calcium-activated chloride conductance in murine airways.
|
Am J Respir Cell Mol Biol
|
2012
|
0.88
|
|
36
|
A rapidly reversible chemical dimerizer system to study lipid signaling in living cells.
|
Angew Chem Int Ed Engl
|
2014
|
0.87
|
|
37
|
CFTR regulates early pathogenesis of chronic obstructive lung disease in βENaC-overexpressing mice.
|
PLoS One
|
2012
|
0.87
|
|
38
|
Tissue clearing for optical anatomy.
|
Angew Chem Int Ed Engl
|
2013
|
0.86
|
|
39
|
FRET-based and other fluorescent proteinase probes.
|
Biotechnol J
|
2014
|
0.86
|
|
40
|
Heterogeneity and timing of translocation and membrane-mediated assembly of different annexins.
|
Exp Cell Res
|
2007
|
0.86
|
|
41
|
Probing phospholipase a(2) with fluorescent phospholipid substrates.
|
Chembiochem
|
2007
|
0.86
|
|
42
|
Research performance of centers of expertise for rare diseases--the influence of network integration, internal resource access and operational experience.
|
Health Policy
|
2012
|
0.85
|
|
43
|
Visualization of intracellular hydrogen peroxide with HyPer, a genetically encoded fluorescent probe.
|
Methods Enzymol
|
2013
|
0.84
|
|
44
|
Investigation of the ligand spectrum of human sterol carrier protein 2 using a direct mass spectrometry assay.
|
Arch Biochem Biophys
|
2007
|
0.84
|
|
45
|
FluoQ: a tool for rapid analysis of multiparameter fluorescence imaging data applied to oscillatory events.
|
ACS Chem Biol
|
2013
|
0.83
|
|
46
|
Fluorescence and bioluminescence procedures for functional proteomics.
|
Proteomics
|
2008
|
0.83
|
|
47
|
Contribution of fluorophores to protein kinase C FRET probe performance.
|
Chembiochem
|
2008
|
0.83
|
|
48
|
In vivo imaging of mouse tumors by a lipidated cathepsin S substrate.
|
Angew Chem Int Ed Engl
|
2014
|
0.82
|
|
49
|
The fatty acid composition of diacylglycerols determines local signaling patterns.
|
Angew Chem Int Ed Engl
|
2013
|
0.82
|
|
50
|
Single- and dual-parameter FRET kinase probes based on pleckstrin.
|
Nat Protoc
|
2006
|
0.82
|
|
51
|
Analysis of protein complex hierarchy in living cells.
|
ACS Chem Biol
|
2008
|
0.82
|
|
52
|
PIP₃ induces the recycling of receptor tyrosine kinases.
|
Sci Signal
|
2014
|
0.81
|
|
53
|
Inositol polyphosphate derivative inhibits Na+ transport and improves fluid dynamics in cystic fibrosis airway epithelia.
|
Am J Physiol Cell Physiol
|
2005
|
0.81
|
|
54
|
Imaging lipids in living cells.
|
Cold Spring Harb Protoc
|
2010
|
0.81
|
|
55
|
Probing lipid- and drug-binding domains with fluorescent dyes.
|
Bioorg Med Chem
|
2007
|
0.81
|
|
56
|
A FlAsH-based cross-linker to study protein interactions in living cells.
|
Angew Chem Int Ed Engl
|
2011
|
0.80
|
|
57
|
Protein tango: the toolbox to capture interacting partners.
|
Angew Chem Int Ed Engl
|
2012
|
0.80
|
|
58
|
The chemical biology of phosphoinositide 3-kinases.
|
Chembiochem
|
2012
|
0.80
|
|
59
|
Antagonists of myo-inositol 3,4,5,6-tetrakisphosphate allow repeated epithelial chloride secretion.
|
Bioorg Med Chem
|
2003
|
0.78
|
|
60
|
Chemical activators of protein phosphatase-1 induce calcium release inside intact cells.
|
Chem Biol
|
2013
|
0.78
|
|
61
|
Shared communication processes within healthcare teams for rare diseases and their influence on healthcare professionals' innovative behavior and patient satisfaction.
|
Implement Sci
|
2011
|
0.78
|
|
62
|
Labeling lipids for imaging in live cells.
|
Cold Spring Harb Protoc
|
2010
|
0.77
|
|
63
|
Imaging H2O2 microdomains in receptor tyrosine kinases signaling.
|
Methods Enzymol
|
2013
|
0.77
|
|
64
|
Can we see PIP(3) and hydrogen peroxide with a single probe?
|
Antioxid Redox Signal
|
2012
|
0.77
|
|
65
|
Cellular uptake of PNA--terpyridine conjugates and its enhancement by Zn2+ ions.
|
J Am Chem Soc
|
2006
|
0.77
|
|
66
|
The impact of the board's strategy-setting role on board-management relations and hospital performance.
|
Health Care Manage Rev
|
2014
|
0.76
|
|
67
|
A new player in the game: epithelial cathepsin S in early cystic fibrosis lung disease.
|
Am J Respir Crit Care Med
|
2014
|
0.76
|
|
68
|
T-CrAsH: a heterologous chemical crosslinker.
|
Chembiochem
|
2014
|
0.76
|
|
69
|
Conformational analysis of a genetically encoded FRET biosensor by SAXS.
|
Biophys J
|
2012
|
0.76
|
|
70
|
Inositol pentakisphosphate isomers bind PH domains with varying specificity and inhibit phosphoinositide interactions.
|
BMC Struct Biol
|
2011
|
0.76
|
|
71
|
Chemical biologists gather in Heidelberg.
|
Nat Chem Biol
|
2009
|
0.75
|
|
72
|
Lipid-induced phenotypes.
|
Nat Chem Biol
|
2006
|
0.75
|
|
73
|
Focus on designing health care structures and services for rare diseases.
|
Health Policy
|
2012
|
0.75
|
|
74
|
Closing the gap between chemistry and biology.
|
Chembiochem
|
2005
|
0.75
|
|
75
|
Transfection of cells with DNA encoding a visible fluorescent protein-tagged lipid-binding domain.
|
Cold Spring Harb Protoc
|
2010
|
0.75
|
|
76
|
Labeling lipids for imaging in fixed cells.
|
Cold Spring Harb Protoc
|
2010
|
0.75
|
|
77
|
A global lipid map reveals host dependency factors conserved across SARS-CoV-2 variants.
|
bioRxiv
|
2022
|
0.75
|
|
78
|
The impact of health care professionals' service orientation on patients' innovative behavior.
|
Health Care Manage Rev
|
2014
|
0.75
|
|
79
|
Photo-Release of 2-Arachidonoylglycerol in Live Cells.
|
J Am Chem Soc
|
2019
|
0.75
|
|
80
|
Editorial. Interview by Adrian Neal.
|
Chembiochem
|
2012
|
0.75
|
|
81
|
The European Molecular Biology Laboratory (EMBL)--its anniversary and its chemistry.
|
Angew Chem Int Ed Engl
|
2014
|
0.75
|
|
82
|
Imaging probes--Introduction.
|
Bioorg Med Chem
|
2011
|
0.75
|
|
83
|
Hospitals' adoption of medical device registers: Evidence from the German Arthroplasty Register.
|
Health Care Manage Rev
|
2017
|
0.75
|