Jan Borén

Author PubWeight™ 122.29‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Subendothelial lipoprotein retention as the initiating process in atherosclerosis: update and therapeutic implications. Circulation 2007 4.62
2 Lipoprotein(a) as a cardiovascular risk factor: current status. Eur Heart J 2010 4.31
3 Subendothelial retention of atherogenic lipoproteins in early atherosclerosis. Nature 2002 3.80
4 SNARE proteins mediate fusion between cytosolic lipid droplets and are implicated in insulin sensitivity. Nat Cell Biol 2007 3.69
5 Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of the European Atherosclerosis Society. Eur Heart J 2013 3.58
6 Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management. Eur Heart J 2011 3.00
7 Overproduction of very low-density lipoproteins is the hallmark of the dyslipidemia in the metabolic syndrome. Arterioscler Thromb Vasc Biol 2008 2.96
8 Transmembrane 6 superfamily member 2 gene variant disentangles nonalcoholic steatohepatitis from cardiovascular disease. Hepatology 2015 2.81
9 The gut microbiota modulates host energy and lipid metabolism in mice. J Lipid Res 2009 2.59
10 Requirement of JNK2 for scavenger receptor A-mediated foam cell formation in atherogenesis. Science 2004 2.38
11 Dual metabolic defects are required to produce hypertriglyceridemia in obese subjects. Arterioscler Thromb Vasc Biol 2011 1.78
12 PNPLA3 I148M (rs738409) genetic variant is associated with hepatocellular carcinoma in obese individuals. Dig Liver Dis 2012 1.70
13 PLD1 and ERK2 regulate cytosolic lipid droplet formation. J Cell Sci 2006 1.67
14 Cytosolic lipid droplets increase in size by microtubule-dependent complex formation. Arterioscler Thromb Vasc Biol 2005 1.62
15 Lipid droplets as dynamic organelles connecting storage and efflux of lipids. Biochim Biophys Acta 2008 1.60
16 Retracted The SNARE protein SNAP23 and the SNARE-interacting protein Munc18c in human skeletal muscle are implicated in insulin resistance/type 2 diabetes. Diabetes 2010 1.51
17 Overproduction of VLDL1 driven by hyperglycemia is a dominant feature of diabetic dyslipidemia. Arterioscler Thromb Vasc Biol 2005 1.50
18 Postnatal constriction, ATP depletion, and cell death in the mature and immature ductus arteriosus. Am J Physiol Regul Integr Comp Physiol 2005 1.49
19 Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development. Proc Natl Acad Sci U S A 2007 1.41
20 Hypoxia converts human macrophages into triglyceride-loaded foam cells. Arterioscler Thromb Vasc Biol 2006 1.40
21 SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis. Eur Heart J 2010 1.40
22 Adipocyte differentiation-related protein promotes fatty acid storage in cytosolic triglycerides and inhibits secretion of very low-density lipoproteins. Arterioscler Thromb Vasc Biol 2006 1.38
23 High-throughput shotgun lipidomics by quadrupole time-of-flight mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2009 1.37
24 The VLDL receptor promotes lipotoxicity and increases mortality in mice following an acute myocardial infarction. J Clin Invest 2011 1.36
25 Proteomics and lipids of lipoproteins isolated at low salt concentrations in D2O/sucrose or in KBr. J Lipid Res 2007 1.24
26 Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro. J Hepatol 2012 1.22
27 Diabetic dyslipidaemia. Curr Opin Lipidol 2006 1.20
28 Fatty liver, insulin resistance, and dyslipidemia. Curr Diab Rep 2008 1.17
29 Triglyceride containing lipid droplets and lipid droplet-associated proteins. Curr Opin Lipidol 2008 1.16
30 Apolipoproteins A-I and B: biosynthesis, role in the development of atherosclerosis and targets for intervention against cardiovascular disease. Vasc Health Risk Manag 2007 1.15
31 Heparan sulfate in perlecan promotes mouse atherosclerosis: roles in lipid permeability, lipid retention, and smooth muscle cell proliferation. Circ Res 2008 1.15
32 Lack of complement factor C3, but not factor B, increases hyperlipidemia and atherosclerosis in apolipoprotein E-/- low-density lipoprotein receptor-/- mice. Arterioscler Thromb Vasc Biol 2004 1.12
33 ApoCIII-enriched LDL in type 2 diabetes displays altered lipid composition, increased susceptibility for sphingomyelinase, and increased binding to biglycan. Diabetes 2009 1.12
34 Retention of low-density lipoprotein in atherosclerotic lesions of the mouse: evidence for a role of lipoprotein lipase. Circ Res 2007 1.11
35 Novel rat model reveals important roles of β-adrenoreceptors in stress-induced cardiomyopathy. Int J Cardiol 2013 1.11
36 A new combined multicompartmental model for apolipoprotein B-100 and triglyceride metabolism in VLDL subfractions. J Lipid Res 2004 1.11
37 Ablation of the very-long-chain fatty acid elongase ELOVL3 in mice leads to constrained lipid storage and resistance to diet-induced obesity. FASEB J 2010 1.10
38 A phospholipase D-dependent process forms lipid droplets containing caveolin, adipocyte differentiation-related protein, and vimentin in a cell-free system. J Biol Chem 2003 1.09
39 ATP depletion in macrophages in the core of advanced rabbit atherosclerotic plaques in vivo. Atherosclerosis 2006 1.09
40 Atherosclerotic mice exhibit systemic inflammation in periadventitial and visceral adipose tissue, liver, and pancreatic islets. Atherosclerosis 2009 1.06
41 Filamins in cardiovascular development. Trends Cardiovasc Med 2007 1.06
42 PARP1 is required for adhesion molecule expression in atherogenesis. Cardiovasc Res 2007 1.06
43 Filamin a mediates HGF/c-MET signaling in tumor cell migration. Int J Cancer 2011 1.05
44 Identification of the proteoglycan binding site in apolipoprotein B48. J Biol Chem 2002 1.04
45 Paradoxical lower serum triglyceride levels and higher type 2 diabetes mellitus susceptibility in obese individuals with the PNPLA3 148M variant. PLoS One 2012 1.02
46 Histamine H1 receptor promotes atherosclerotic lesion formation by increasing vascular permeability for low-density lipoproteins. Arterioscler Thromb Vasc Biol 2010 1.01
47 Targeting GGTase-I activates RHOA, increases macrophage reverse cholesterol transport, and reduces atherosclerosis in mice. Circulation 2013 1.01
48 Mechanism of lipoprotein retention by the extracellular matrix. Curr Opin Lipidol 2004 1.00
49 PAQR-2 regulates fatty acid desaturation during cold adaptation in C. elegans. PLoS Genet 2013 1.00
50 Cadmium exposure is accompanied by increased prevalence and future growth of atherosclerotic plaques in 64-year-old women. J Intern Med 2012 0.97
51 The endogenous estradiol metabolite 2-methoxyestradiol reduces atherosclerotic lesion formation in female apolipoprotein E-deficient mice. Endocrinology 2007 0.96
52 Endothelial cells are activated during hypoxia via endoglin/ALK-1/SMAD1/5 signaling in vivo and in vitro. Biochem Biophys Res Commun 2010 0.96
53 Molecular mechanism for changes in proteoglycan binding on compositional changes of the core and the surface of low-density lipoprotein-containing human apolipoprotein B100. Arterioscler Thromb Vasc Biol 2004 0.94
54 Rapid quantification of yeast lipid using microwave-assisted total lipid extraction and HPLC-CAD. Anal Chem 2013 0.94
55 ApoE-/- PGC-1α-/- mice display reduced IL-18 levels and do not develop enhanced atherosclerosis. PLoS One 2010 0.91
56 Postprandial accumulation of chylomicrons and chylomicron remnants is determined by the clearance capacity. Atherosclerosis 2012 0.91
57 Protein disulfide isomerase increases in myocardial endothelial cells in mice exposed to chronic hypoxia: a stimulatory role in angiogenesis. Am J Physiol Heart Circ Physiol 2009 0.90
58 Influence of peroxisome proliferator-activated receptor alpha agonists on the intracellular turnover and secretion of apolipoprotein (Apo) B-100 and ApoB-48. J Biol Chem 2002 0.89
59 The assembly of lipid droplets and its relation to cellular insulin sensitivity. Biochem Soc Trans 2009 0.89
60 15-Lipoxygenase-2 expression in human macrophages induces chemokine secretion and T cell migration. Atherosclerosis 2007 0.89
61 Role of ADP ribosylation factor 1 in the assembly and secretion of ApoB-100-containing lipoproteins. Arterioscler Thromb Vasc Biol 2004 0.88
62 Hypoxia-induced and calpain-dependent cleavage of filamin A regulates the hypoxic response. Proc Natl Acad Sci U S A 2014 0.87
63 Apolipoprotein B secretory regulation by degradation. Arterioscler Thromb Vasc Biol 2012 0.86
64 The minor allele of the missense polymorphism Ser251Pro in perilipin 2 (PLIN2) disrupts an α-helix, affects lipolysis, and is associated with reduced plasma triglyceride concentration in humans. FASEB J 2013 0.85
65 Targeting filamin A reduces K-RAS-induced lung adenocarcinomas and endothelial response to tumor growth in mice. Mol Cancer 2012 0.85
66 Tissue-specific targeting for cardiovascular gene transfer. Potential vectors and future challenges. Curr Gene Ther 2004 0.85
67 Arachidonate 15-lipoxygenase type B knockdown leads to reduced lipid accumulation and inflammation in atherosclerosis. PLoS One 2012 0.84
68 Establishment of a transgenic mouse model specifically expressing human serum amyloid A in adipose tissue. PLoS One 2011 0.84
69 Rip2 deficiency leads to increased atherosclerosis despite decreased inflammation. Circ Res 2011 0.84
70 Relation of the size and intracellular sorting of apoB to the formation of VLDL 1 and VLDL 2. J Lipid Res 2004 0.84
71 Increased expression of the very low-density lipoprotein receptor mediates lipid accumulation in clear-cell renal cell carcinoma. PLoS One 2012 0.84
72 A mouse model reveals an important role for catecholamine-induced lipotoxicity in the pathogenesis of stress-induced cardiomyopathy. Eur J Heart Fail 2012 0.83
73 Cholesteryl esters accumulate in the heart in a porcine model of ischemia and reperfusion. PLoS One 2013 0.83
74 Epigallocatechin gallate increases the formation of cytosolic lipid droplets and decreases the secretion of apoB-100 VLDL. J Lipid Res 2005 0.83
75 Innate immune receptor NOD2 promotes vascular inflammation and formation of lipid-rich necrotic cores in hypercholesterolemic mice. Eur J Immunol 2014 0.82
76 Dietary α-linolenic acid diminishes experimental atherogenesis and restricts T cell-driven inflammation. Eur Heart J 2011 0.82
77 Increased expression of STK25 leads to impaired glucose utilization and insulin sensitivity in mice challenged with a high-fat diet. FASEB J 2013 0.82
78 Disturbed cholesterol homeostasis in hormone-sensitive lipase-null mice. Am J Physiol Endocrinol Metab 2008 0.81
79 The COBLL1 C allele is associated with lower serum insulin levels and lower insulin resistance in overweight and obese children. Diabetes Metab Res Rev 2013 0.81
80 Paradoxical dissociation between hepatic fat content and de novo lipogenesis due to PNPLA3 sequence variant. J Clin Endocrinol Metab 2015 0.81
81 Deletion of L-selectin increases atherosclerosis development in ApoE-/- mice. PLoS One 2011 0.80
82 A non-conservative polymorphism in the IL-6 signal transducer (IL6ST)/gp130 is associated with myocardial infarction in a hypertensive population. Regul Pept 2007 0.80
83 Allele-specific regulation of MTTP expression influences the risk of ischemic heart disease. J Lipid Res 2010 0.80
84 Cadmium exposure, intercellular adhesion molecule-1 and peripheral artery disease: a cohort and an experimental study. BMJ Open 2013 0.79
85 Expression of scavenger receptor class B type I in gallbladder columnar epithelium. J Gastroenterol Hepatol 2002 0.79
86 Genetic variation in SULF2 is associated with postprandial clearance of triglyceride-rich remnant particles and triglyceride levels in healthy subjects. PLoS One 2013 0.79
87 The importance of GLUT3 for de novo lipogenesis in hypoxia-induced lipid loading of human macrophages. PLoS One 2012 0.79
88 Impact of hypoxia, simulated ischemia and reperfusion in HL-1 cells on the expression of FKBP12/FKBP12.6 and intracellular calcium dynamics. Biochem Biophys Res Commun 2012 0.79
89 Treatment of hyaluronan accumulation ameliorates high-fat diet-induced insulin resistance in mice. Diabetes 2013 0.78
90 Optimization of N-methyl-N-[tert-butyldimethylsilyl]trifluoroacetamide as a derivatization agent for determining isotopic enrichment of glycerol in very-low density lipoproteins. Rapid Commun Mass Spectrom 2010 0.78
91 Hepatic lipogenesis and a marker of hepatic lipid oxidation, predict postprandial responses of triglyceride-rich lipoproteins. Obesity (Silver Spring) 2014 0.78
92 Endothelial dysfunction in growth hormone transgenic mice. Clin Sci (Lond) 2006 0.78
93 Augmented levels of CD44 in macrophages from atherosclerotic subjects: a possible IL-6-CD44 feedback loop? Atherosclerosis 2006 0.78
94 How does mutant proprotein convertase neural apoptosis-regulated convertase 1 induce autosomal dominant hypercholesterolemia? Arterioscler Thromb Vasc Biol 2004 0.78
95 Adiponectin receptor 2 deficiency results in reduced atherosclerosis in the brachiocephalic artery in apolipoprotein E deficient mice. PLoS One 2013 0.76
96 ARF6 regulates neuron differentiation through glucosylceramide synthase. PLoS One 2013 0.76
97 The formation of lipid droplets: possible role in the development of insulin resistance/type 2 diabetes. Prostaglandins Leukot Essent Fatty Acids 2011 0.76
98 ATP depletion and cell death in the neonatal lamb ductus arteriosus. Pediatr Res 2005 0.76
99 Electrophysiological effects of lysophosphatidylcholine on HL-1 cardiomyocytes assessed with a microelectrode array system. Cell Physiol Biochem 2012 0.76
100 Kinetics of plasma triglycerides in abdominal obesity. Curr Opin Lipidol 2016 0.76
101 Correction: Caenorhabditis elegans PAQR-2 and IGLR-2 Protect against Glucose Toxicity by Modulating Membrane Lipid Composition. PLoS Genet 2016 0.75
102 [A research assistant program in Gothenburg refutes the myth about medical students' lack of interest in research]. Lakartidningen 2007 0.75
103 Hypoxia-induced regulation of the very low density lipoprotein receptor. Biochem Biophys Res Commun 2013 0.75
104 [Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society]. Turk Kardiyol Dern Ars 2015 0.75
105 The IRS1 rs2943641 variant and risk of future cancer among morbidly obese individuals. J Clin Endocrinol Metab 2013 0.75
106 Statement of Retraction. The SNARE Protein SNAP23 and the SNARE-Interacting Protein Munc18c in Human Skeletal Muscle Are Implicated in Insulin Resistance/Type 2 Diabetes. Diabetes 2010;59:1870-1878. DOI: 10.2337/db09-1503. PMID: 20460426. Diabetes 2017 0.75
107 Postnatal essential fatty acid deficiency in mice affects lipoproteins, hepatic lipids, fatty acids and mRNA expression. Prostaglandins Leukot Essent Fatty Acids 2011 0.75
108 CD44-deficiency on hematopoietic cells limits T-cell number but does not protect against atherogenesis in LDL receptor-deficient mice. Atherosclerosis 2009 0.75
109 Overexpression of apolipoprotein B attenuates pathologic cardiac remodeling and hypertrophy in response to catecholamines and after myocardial infarction in mice. Scand J Clin Lab Invest 2012 0.75