Published in Neuron on March 27, 2008
Normal gut microbiota modulates brain development and behavior. Proc Natl Acad Sci U S A (2011) 6.16
Behavioural phenotyping assays for mouse models of autism. Nat Rev Neurosci (2010) 5.27
A computational framework for ultrastructural mapping of neural circuitry. PLoS Biol (2009) 4.22
The interplay between the intestinal microbiota and the brain. Nat Rev Microbiol (2012) 2.83
Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice. Neuron (2009) 2.43
A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Cell (2010) 2.37
Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spinal and bulbar muscular atrophy. Neuron (2009) 2.26
Removing obstacles in neuroscience drug discovery: the future path for animal models. Neuropsychopharmacology (2008) 2.16
Prkcz null mice show normal learning and memory. Nature (2013) 2.06
Oxytocin enables maternal behaviour by balancing cortical inhibition. Nature (2015) 2.04
Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory study. Physiol Genomics (2008) 1.76
Modeling autism by SHANK gene mutations in mice. Neuron (2013) 1.64
The therapeutic mode of action of 4-aminopyridine in cerebellar ataxia. J Neurosci (2010) 1.60
Zebrafish models for translational neuroscience research: from tank to bedside. Trends Neurosci (2014) 1.51
MeCP2-mediated transcription repression in the basolateral amygdala may underlie heightened anxiety in a mouse model of Rett syndrome. J Neurosci (2009) 1.50
Mice with altered serotonin 2C receptor RNA editing display characteristics of Prader-Willi syndrome. Neurobiol Dis (2010) 1.46
Translational approaches to treatment-induced symptoms in cancer patients. Nat Rev Clin Oncol (2012) 1.38
Altered ultrasonic vocalization and impaired learning and memory in Angelman syndrome mouse model with a large maternal deletion from Ube3a to Gabrb3. PLoS One (2010) 1.37
An essential role for histone deacetylase 4 in synaptic plasticity and memory formation. J Neurosci (2012) 1.35
KCa channels as therapeutic targets in episodic ataxia type-2. J Neurosci (2010) 1.27
The apical complex couples cell fate and cell survival to cerebral cortical development. Neuron (2010) 1.22
Fractalkine regulation of microglial physiology and consequences on the brain and behavior. Front Cell Neurosci (2014) 1.20
Cytisine-based nicotinic partial agonists as novel antidepressant compounds. J Pharmacol Exp Ther (2009) 1.18
A novel social proximity test suggests patterns of social avoidance and gaze aversion-like behavior in BTBR T+ tf/J mice. Behav Brain Res (2010) 1.17
A novel high-throughput imaging system for automated analyses of avoidance behavior in zebrafish larvae. Behav Brain Res (2011) 1.15
Inhibition of GSK3 by lithium, from single molecules to signaling networks. Front Mol Neurosci (2012) 1.14
Serotonin-prefrontal cortical circuitry in anxiety and depression phenotypes: pivotal role of pre- and post-synaptic 5-HT1A receptor expression. Front Behav Neurosci (2014) 1.12
What does CNTNAP2 reveal about autism spectrum disorder? Trends Mol Med (2012) 1.12
Astrocyte control of synaptic NMDA receptors contributes to the progressive development of temporal lobe epilepsy. Proc Natl Acad Sci U S A (2013) 1.03
The surveillance state of behavioral automation. Curr Opin Neurobiol (2011) 1.01
Rapid assessment of sleep-wake behavior in mice. J Biol Rhythms (2012) 1.01
Maternal antibodies from mothers of children with autism alter brain growth and social behavior development in the rhesus monkey. Transl Psychiatry (2013) 1.00
Neonatal catch up growth increases diabetes susceptibility but improves behavioral and cardiovascular outcomes of low birth weight male mice. Pediatr Res (2009) 0.99
Modulation of CGRP-induced light aversion in wild-type mice by a 5-HT(1B/D) agonist. J Neurosci (2012) 0.98
Comprehensive behavioral characterization of an APP/PS-1 double knock-in mouse model of Alzheimer's disease. Alzheimers Res Ther (2013) 0.97
Genetic dissection of the role of cannabinoid type-1 receptors in the emotional consequences of repeated social stress in mice. Neuropsychopharmacology (2012) 0.95
Forebrain HCN1 channels contribute to hypnotic actions of ketamine. Anesthesiology (2013) 0.95
Transgenic APP expression during postnatal development causes persistent locomotor hyperactivity in the adult. Mol Neurodegener (2012) 0.94
Memory, mood, dopamine, and serotonin in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse model of basal ganglia injury. Neurobiol Dis (2008) 0.93
Translational research in bipolar disorder: emerging insights from genetically based models. Mol Psychiatry (2010) 0.91
Radioprotection of the brain white matter by Mn(III) n-Butoxyethylpyridylporphyrin-based superoxide dismutase mimic MnTnBuOE-2-PyP5+. Mol Cancer Ther (2014) 0.90
Removing the cloak of invisibility: phenotyping the mouse. Dis Model Mech (2008) 0.90
Anxiety in mice and men: a comparison. J Neural Transm (Vienna) (2009) 0.90
Resistance to early-life stress in mice: effects of genetic background and stress duration. Front Behav Neurosci (2011) 0.90
Post-training dephosphorylation of eEF-2 promotes protein synthesis for memory consolidation. PLoS One (2009) 0.89
The clinical implications of mouse models of enhanced anxiety. Future Neurol (2011) 0.89
Genetic disruption of Met signaling impairs GABAergic striatal development and cognition. Neuroscience (2010) 0.89
α4β2 nicotinic acetylcholine receptor partial agonists with low intrinsic efficacy have antidepressant-like properties. Behav Pharmacol (2011) 0.88
Cerebellar associative sensory learning defects in five mouse autism models. Elife (2015) 0.87
Anxiety- and depression-like behavior in mice lacking the CD157/BST1 gene, a risk factor for Parkinson's disease. Front Behav Neurosci (2014) 0.86
Plasma neurofilament heavy chain levels correlate to markers of late stage disease progression and treatment response in SOD1(G93A) mice that model ALS. PLoS One (2012) 0.86
A fully automated high-throughput training system for rodents. PLoS One (2013) 0.86
Microglia contribute to circuit defects in Mecp2 null mice independent of microglia-specific loss of Mecp2 expression. Elife (2016) 0.86
Evaluation of study design variables and their impact on food-maintained operant responding in mice. Behav Brain Res (2009) 0.85
Neurobehavioral phenotype of C57BL/6J mice prenatally and neonatally exposed to cigarette smoke. Neurotoxicol Teratol (2013) 0.85
SYNGAP1: Mind the Gap. Front Cell Neurosci (2016) 0.84
Age-related changes in behavior in C57BL/6J mice from young adulthood to middle age. Mol Brain (2016) 0.83
Mice and rats achieve similar levels of performance in an adaptive decision-making task. Front Syst Neurosci (2014) 0.82
Bad light stops play. EMBO Rep (2011) 0.82
Sex-dependent changes in metabolism and behavior, as well as reduced anxiety after eliminating ventromedial hypothalamus excitatory output. Mol Metab (2015) 0.81
Behavioral assessment of NIH Swiss mice acutely intoxicated with tetramethylenedisulfotetramine. Neurotoxicol Teratol (2014) 0.81
Data calibration and reduction allows to visualize behavioural profiles of psychosocial influences in mice towards clinical domains. Eur Arch Psychiatry Clin Neurosci (2014) 0.81
Effects of background mutations and single nucleotide polymorphisms (SNPs) on the Disc1 L100P behavioral phenotype associated with schizophrenia in mice. Behav Brain Funct (2014) 0.80
Using the Morris water maze to assess spatial learning and memory in weanling mice. PLoS One (2015) 0.80
New insights into behaviour using mouse ENU mutagenesis. Hum Mol Genet (2012) 0.80
Intermittent hypoxia can aggravate motor neuronal loss and cognitive dysfunction in ALS mice. PLoS One (2013) 0.79
Clinical testing and spinal cord removal in a mouse model for amyotrophic lateral sclerosis (ALS). J Vis Exp (2012) 0.79
Hitchhiking of host biology by beneficial symbionts enhances transmission. Sci Rep (2014) 0.79
A quantitative analysis of the effects of qualitatively different reinforcers on fixed ratio responding in inbred strains of mice. Neurobiol Learn Mem (2013) 0.79
Trial-unique, delayed nonmatching-to-location (TUNL) touchscreen testing for mice: sensitivity to dorsal hippocampal dysfunction. Psychopharmacology (Berl) (2015) 0.79
Schizophrenia and Depression Co-Morbidity: What We have Learned from Animal Models. Front Psychiatry (2015) 0.79
Deletion of the Chd6 exon 12 affects motor coordination. Mamm Genome (2010) 0.79
Fibroblast growth factor deficiencies impact anxiety-like behavior and the serotonergic system. Behav Brain Res (2014) 0.78
Effect of chronic glutathione deficiency on the behavioral phenotype of Gclm-/- knockout mice. Neurotoxicol Teratol (2012) 0.78
Complete or partial reduction of the Met receptor tyrosine kinase in distinct circuits differentially impacts mouse behavior. J Neurodev Disord (2015) 0.78
Nicotine withdrawal. Curr Top Behav Neurosci (2015) 0.78
Heterozygous deletion of α-neurexin I or α-neurexin II results in behaviors relevant to autism and schizophrenia. Behav Neurosci (2015) 0.77
Administration of Non-Absorbable Antibiotics to Pregnant Mice to Perturb the Maternal Gut Microbiota Is Associated with Alterations in Offspring Behavior. PLoS One (2016) 0.77
PX-RICS-deficient mice mimic autism spectrum disorder in Jacobsen syndrome through impaired GABAA receptor trafficking. Nat Commun (2016) 0.76
Behavioral characterization of mice overexpressing human dysbindin-1. Mol Brain (2014) 0.76
Region-Specific Disruption of Adenylate Cyclase Type 1 Gene Differentially Affects Somatosensorimotor Behaviors in Mice. eNeuro (2014) 0.76
Behavioral stress reduces RIP140 expression in astrocyte and increases brain lipid accumulation. Brain Behav Immun (2015) 0.76
Development and validation of a sensitive entropy-based measure for the water maze. Front Integr Neurosci (2009) 0.76
Emotional regulatory function of receptor interacting protein 140 revealed in the ventromedial hypothalamus. Brain Behav Immun (2014) 0.76
A new mouse model to study compensatory mechanisms that support normal motor function in Parkinson's disease. J Biochem Pharmacol Res (2014) 0.76
Mouse models of mutations and variations in autism spectrum disorder-associated genes: mice expressing Caps2/Cadps2 copy number and alternative splicing variants. Int J Environ Res Public Health (2013) 0.76
Partial rodent genetic models for bipolar disorder. Curr Top Behav Neurosci (2011) 0.76
Persistent post-stroke depression in mice following unilateral medial prefrontal cortical stroke. Transl Psychiatry (2016) 0.75
Region-Specific Disruption of Adenylate Cyclase Type 1 Gene Differentially Affects Somatosensorimotor Behaviors in Mice(1,2,3). eNeuro (2014) 0.75
Characterization of PTZ-induced seizure susceptibility in a down syndrome mouse model that overexpresses CSTB. PLoS One (2011) 0.75
Untapped resources for pharmacogenomic discovery in psychiatry. Curr Opin Mol Ther (2008) 0.75
Calcineurin downregulation in the amygdala is sufficient to induce anxiety-like and depression-like behaviors in C57BL/6J male mice. Biol Psychiatry (2014) 0.75
Comparison of In Vivo and Ex Vivo MRI for the Detection of Structural Abnormalities in a Mouse Model of Tauopathy. Front Neuroinform (2017) 0.75
Roundabout receptor 2 maintains inhibitory control of the adult midbrain. Elife (2017) 0.75
Behavioral and neuroanatomical abnormalities in pleiotrophin knockout mice. PLoS One (2014) 0.75
Genetically identified spinal interneurons integrating tactile afferents for motor control. J Neurophysiol (2015) 0.75
Optimization of a Clinically Relevant Model of White Matter Stroke in Mice: Histological and Functional Evidences. J Neurol Neurosurg (2015) 0.75
Selective chemical genetic inhibition of protein kinase C epsilon reduces ethanol consumption in mice. Neuropharmacology (2016) 0.75
Protein-restricted diet during pregnancy after insemination alters behavioral phenotypes of the progeny. Genes Nutr (2017) 0.75